메뉴 건너뛰기




Volumn 9, Issue 2, 2007, Pages

Nanosystems for simultaneous imaging and drug delivery to T cells

Author keywords

Drug delivery; Nanoparticles; Noninvasive imaging; T cells

Indexed keywords

ALBUMIN; BOVINE SERUM ALBUMIN; CONTRAST MEDIUM; DENDRIMER; DOXORUBICIN; FLUOROCHROME; FLUORODEOXYGLUCOSE F 18; FOLIC ACID; GADOLINIUM; GADOLINIUM PENTETATE; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; IMMUNOSUPPRESSIVE AGENT; INDIUM 111; IRON OXIDE; LIGAND; LIPOSOME; MACROGOL; MANGANESE CHLORIDE; NANOPARTICLE; POLYAMIDOAMINE; POLYGLACTIN; POLYGLYCOLIC ACID; POLYLACTIC ACID; STREPTAVIDIN; SUPERPARAMAGNETIC IRON OXIDE; T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE RECEPTOR; TECHNETIUM 99M; TRANSACTIVATOR PROTEIN; UNINDEXED DRUG;

EID: 34250685362     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/aapsj0902019     Document Type: Review
Times cited : (78)

References (89)
  • 1
    • 0027328370 scopus 로고
    • Autoimmune-disease
    • Steinman L. Autoimmune-disease. Sci Am. 1993;269:106.
    • (1993) Sci Am , vol.269 , pp. 106
    • Steinman, L.1
  • 2
    • 33744762212 scopus 로고    scopus 로고
    • Biological therapies directed against cells in autoimmune disease
    • Hasler P. Biological therapies directed against cells in autoimmune disease. Springer Semin Immunopathol. 2006;27:443-456.
    • (2006) Springer Semin Immunopathol , vol.27 , pp. 443-456
    • Hasler, P.1
  • 3
    • 3543109183 scopus 로고    scopus 로고
    • T-cell immunotherapy of allergic disease: The role of CD8+ T cells
    • Ogg GS. T-cell immunotherapy of allergic disease: the role of CD8+ T cells. Curr Opin Allergy Clin Immunol. 2003;3:475-479.
    • (2003) Curr Opin Allergy Clin Immunol , vol.3 , pp. 475-479
    • Ogg, G.S.1
  • 4
    • 0033166771 scopus 로고    scopus 로고
    • Distribution of activated T cells migrating through the body: A matter of life and death
    • Westermann J, Bode U. Distribution of activated T cells migrating through the body: a matter of life and death. Immunol Today. 1999;20:302-306.
    • (1999) Immunol Today , vol.20 , pp. 302-306
    • Westermann, J.1    Bode, U.2
  • 5
    • 0035706160 scopus 로고    scopus 로고
    • Migration of naive, effector and memory T cells: Implications for the regulation of immune responses
    • Westermann J, Ehlers EM, Exton MS, Kaiser M, Bode U. Migration of naive, effector and memory T cells: implications for the regulation of immune responses. Immunol Rev. 2001;184:20-37.
    • (2001) Immunol Rev , vol.184 , pp. 20-37
    • Westermann, J.1    Ehlers, E.M.2    Exton, M.S.3    Kaiser, M.4    Bode, U.5
  • 6
    • 0035928636 scopus 로고    scopus 로고
    • Migration of T cells in vivo: Molecular mechanisms and clinical implications
    • Westermann J, Engelhardt B, Hoffmann JC. Migration of T cells in vivo: molecular mechanisms and clinical implications. Ann Intern Med. 2001;135:279-295.
    • (2001) Ann Intern Med , vol.135 , pp. 279-295
    • Westermann, J.1    Engelhardt, B.2    Hoffmann, J.C.3
  • 8
    • 0038731005 scopus 로고    scopus 로고
    • Migration and T-lymphocyte effector function
    • Bradley LM. Migration and T-lymphocyte effector function. Curr Opin Immunol. 2003; 15:343-348.
    • (2003) Curr Opin Immunol , vol.15 , pp. 343-348
    • Bradley, L.M.1
  • 9
    • 0035846910 scopus 로고    scopus 로고
    • T cell receptor-MHC interactions up close
    • Hennecke J, Wiley DC. T cell receptor-MHC interactions up close. Cell 2001;104:1-4.
    • (2001) Cell , vol.104 , pp. 1-4
    • Hennecke, J.1    Wiley, D.C.2
  • 10
    • 0028120414 scopus 로고
    • T cell receptor-MHC class I peptide interactions: Affinity, kinetics, and specificity
    • Corr M, Slanetz AE, Boyd LF, et al. T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity. Science. 1994;265:946-949.
    • (1994) Science , vol.265 , pp. 946-949
    • Corr, M.1    Slanetz, A.E.2    Boyd, L.F.3
  • 11
    • 0028410566 scopus 로고
    • Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes
    • Sykulev Y, Brumnark A, Jackson M, Cohen RJ, Peterson PA, Eisen HN. Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity 1994; 1:15-22.
    • (1994) Immunity , vol.1 , pp. 15-22
    • Sykulev, Y.1    Brumnark, A.2    Jackson, M.3    Cohen, R.J.4    Peterson, P.A.5    Eisen, H.N.6
  • 12
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman JD, Moss PA, Goulder PJ, et al. Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996;274:94-96.
    • (1996) Science , vol.274 , pp. 94-96
    • Altman, J.D.1    Moss, P.A.2    Goulder, P.J.3
  • 13
  • 14
    • 0032938860 scopus 로고    scopus 로고
    • MHC-based diagnostics and therapeutics - clinical applications for disease-linked genes
    • Howard MC, Spack EG, Choudhury K, Greten TF, Schneck JP. MHC-based diagnostics and therapeutics - clinical applications for disease-linked genes. Immunol Today. 1999;20:161-165.
    • (1999) Immunol Today , vol.20 , pp. 161-165
    • Howard, M.C.1    Spack, E.G.2    Choudhury, K.3    Greten, T.F.4    Schneck, J.P.5
  • 15
    • 0036549509 scopus 로고    scopus 로고
    • Tracking T cells with tetramers: New tales from new tools
    • Klenerman P, Cerundolo V, Dunbar PR. Tracking T cells with tetramers: new tales from new tools. Nat Rev Immunol. 2002;2:263-272.
    • (2002) Nat Rev Immunol , vol.2 , pp. 263-272
    • Klenerman, P.1    Cerundolo, V.2    Dunbar, P.R.3
  • 17
    • 0035129284 scopus 로고    scopus 로고
    • Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II-peptide chimera
    • Casares S, Stan AC, Bona CA, Brumeanu TD. Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II-peptide chimera. Nat Biotechnol. 2001;19:142-147.
    • (2001) Nat Biotechnol , vol.19 , pp. 142-147
    • Casares, S.1    Stan, A.C.2    Bona, C.A.3    Brumeanu, T.D.4
  • 18
    • 33745405518 scopus 로고    scopus 로고
    • Imaging the choreography of lymphocyte trafficking and the immune response
    • Cahalan MD, Parker I. Imaging the choreography of lymphocyte trafficking and the immune response. Curr Opin Immunol. 2006;18:476-482.
    • (2006) Curr Opin Immunol , vol.18 , pp. 476-482
    • Cahalan, M.D.1    Parker, I.2
  • 20
    • 0042405137 scopus 로고    scopus 로고
    • Whole-body analysis of T cell responses
    • Reinhardt RL, Jenkins MK. Whole-body analysis of T cell responses. Curr Opin Immunol. 2003; 15:366-371.
    • (2003) Curr Opin Immunol , vol.15 , pp. 366-371
    • Reinhardt, R.L.1    Jenkins, M.K.2
  • 21
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK. Visualizing the generation of memory CD4 T cells in the whole body. Nature. 2001;410:101-105.
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 22
    • 0036831870 scopus 로고    scopus 로고
    • 2-photon tissue imaging: Seeing the immune system in a fresh light
    • Cahalan MD, Parker I, Wei SH, Miller MJ. 2-photon tissue imaging: seeing the immune system in a fresh light. Nat Rev Immunol. 2002;2:872-880.
    • (2002) Nat Rev Immunol , vol.2 , pp. 872-880
    • Cahalan, M.D.1    Parker, I.2    Wei, S.H.3    Miller, M.J.4
  • 24
    • 0037418183 scopus 로고    scopus 로고
    • Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy
    • Miller MJ, Wei SH, Cahalan MD, Parker I. Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy. Proc Natl Acad Sci USA. 2003; 100:2604-2609.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2604-2609
    • Miller, M.J.1    Wei, S.H.2    Cahalan, M.D.3    Parker, I.4
  • 25
    • 0026814613 scopus 로고
    • The use of 2-[18F]fluoro-2-deoxy-D-glucose as a potential in vitro agent for labelling human granulocytes for clinical studies by positron emission tomography
    • Osman S, Danpure HJ. The use of 2-[18F]fluoro-2-deoxy-D-glucose as a potential in vitro agent for labelling human granulocytes for clinical studies by positron emission tomography. Int J Rad Appl Instrum B. 1992; 19:183-190.
    • (1992) Int J Rad Appl Instrum B , vol.19 , pp. 183-190
    • Osman, S.1    Danpure, H.J.2
  • 26
    • 0023830096 scopus 로고
    • Inflammation: Imaging with Tc-99m HMPAO-labeled leukocytes
    • Roddie ME, Peters AM, Danpure HJ, et al. Inflammation: imaging with Tc-99m HMPAO-labeled leukocytes. Radiology. 1988;166:767-772.
    • (1988) Radiology , vol.166 , pp. 767-772
    • Roddie, M.E.1    Peters, A.M.2    Danpure, H.J.3
  • 27
    • 0036839884 scopus 로고    scopus 로고
    • Advancing animal models of neoplasia through in vivo bioluminescence imaging
    • Edinger M, Cao YA, Hornig YS, et al. Advancing animal models of neoplasia through in vivo bioluminescence imaging. Eur J Cancer. 2002;38:2128-2136.
    • (2002) Eur J Cancer , vol.38 , pp. 2128-2136
    • Edinger, M.1    Cao, Y.A.2    Hornig, Y.S.3
  • 28
  • 29
    • 0035881597 scopus 로고    scopus 로고
    • Adoptive immuno-therapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p4O subunit
    • Costa GL, Sandora MR, Nakajima A, et al. Adoptive immuno-therapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p4O subunit. J Immunol. 2001;167:2379-2387.
    • (2001) J Immunol , vol.167 , pp. 2379-2387
    • Costa, G.L.1    Sandora, M.R.2    Nakajima, A.3
  • 30
    • 0035003202 scopus 로고    scopus 로고
    • Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis
    • Nakajima A, Seroogy CM, Sandora MR, et al. Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. J Clin Invest. 2001;107:1293-1301.
    • (2001) J Clin Invest , vol.107 , pp. 1293-1301
    • Nakajima, A.1    Seroogy, C.M.2    Sandora, M.R.3
  • 31
    • 0042242608 scopus 로고    scopus 로고
    • Micro-PET imaging and small animal models of disease
    • Herschman HR. Micro-PET imaging and small animal models of disease. Curr Opin Immunol. 2003; 15:378-384.
    • (2003) Curr Opin Immunol , vol.15 , pp. 378-384
    • Herschman, H.R.1
  • 32
    • 27644443674 scopus 로고    scopus 로고
    • Magnetic resonance and fluorescence based molecular imaging technologies
    • Sosnovik D, Weissleder R. Magnetic resonance and fluorescence based molecular imaging technologies. Prog Drug Res. 2005;62:83-115.
    • (2005) Prog Drug Res , vol.62 , pp. 83-115
    • Sosnovik, D.1    Weissleder, R.2
  • 34
    • 0036009638 scopus 로고    scopus 로고
    • Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles
    • Wunderbaldinger P, Josephson L, Weissleder R. Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles. Bioconjug Chem. 2002;13:264-268.
    • (2002) Bioconjug Chem , vol.13 , pp. 264-268
    • Wunderbaldinger, P.1    Josephson, L.2    Weissleder, R.3
  • 35
    • 33748370299 scopus 로고    scopus 로고
    • In vivo cellular imaging of lymphocyte trafficking by MRI: A tumor model approach to cell-based anticancer therapy
    • Smimov P, Lavergne E, Gazeau F, et al. In vivo cellular imaging of lymphocyte trafficking by MRI: a tumor model approach to cell-based anticancer therapy. Magn Reson Med. 2006;56:498-508.
    • (2006) Magn Reson Med , vol.56 , pp. 498-508
    • Smimov, P.1    Lavergne, E.2    Gazeau, F.3
  • 36
    • 20144388029 scopus 로고    scopus 로고
    • Cell tagging with clinically approved iron oxides: Feasibility and effect of lipofection, particle size, and surface coating on labeling efficiency
    • Matuszewski L, Persigehl T, Wall A, et al. Cell tagging with clinically approved iron oxides: feasibility and effect of lipofection, particle size, and surface coating on labeling efficiency. Radiology. 2005;235:155-161.
    • (2005) Radiology , vol.235 , pp. 155-161
    • Matuszewski, L.1    Persigehl, T.2    Wall, A.3
  • 38
    • 0019463519 scopus 로고
    • Targeting of drugs: Implications in medicine
    • Gregoriadis G. Targeting of drugs: implications in medicine. Lancet. 1981;318:241-246.
    • (1981) Lancet , vol.318 , pp. 241-246
    • Gregoriadis, G.1
  • 39
    • 34250651095 scopus 로고
    • The carrier potential of liposomes in biology and medicine
    • Gregoriadis G. The carrier potential of liposomes in biology and medicine. N Engl J Med. 1976;704:110.
    • (1976) N Engl J Med , vol.704 , pp. 110
    • Gregoriadis, G.1
  • 40
    • 0015899008 scopus 로고
    • Drug entrapment in liposomes
    • Gregoriadis G. Drug entrapment in liposomes. FEBS Lett. 1973;36:292-296.
    • (1973) FEBS Lett , vol.36 , pp. 292-296
    • Gregoriadis, G.1
  • 43
    • 0030161222 scopus 로고    scopus 로고
    • Liposomes as delivery agents for medical imaging
    • Torchilin VP. Liposomes as delivery agents for medical imaging. Mol Med Today. 1996;2:242-249.
    • (1996) Mol Med Today , vol.2 , pp. 242-249
    • Torchilin, V.P.1
  • 45
    • 0027514941 scopus 로고
    • Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases
    • Haran G, Cohen R, Bar LY, Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim Biophys Acta. 1993; 1151:201-215.
    • (1993) Biochim Biophys Acta , vol.1151 , pp. 201-215
    • Haran, G.1    Cohen, R.2    Bar, L.Y.3    Barenholz, Y.4
  • 46
    • 0038797831 scopus 로고    scopus 로고
    • Ligand-targeted liposomal anticancer drugs
    • Sapra P, Allen TM. Ligand-targeted liposomal anticancer drugs. Prog Lipid Res. 2003;42:439-462.
    • (2003) Prog Lipid Res , vol.42 , pp. 439-462
    • Sapra, P.1    Allen, T.M.2
  • 48
    • 0034031080 scopus 로고    scopus 로고
    • Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump
    • Goren D, Horowitz AT, Tzemach D, Tarshish M, Zalipsky S, Gabizon A. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump. Clin Cancer Res. 2000;6:1949-1957.
    • (2000) Clin Cancer Res , vol.6 , pp. 1949-1957
    • Goren, D.1    Horowitz, A.T.2    Tzemach, D.3    Tarshish, M.4    Zalipsky, S.5    Gabizon, A.6
  • 49
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov. 2005;4:145-160.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 145-160
    • Torchilin, V.P.1
  • 51
    • 0036161575 scopus 로고    scopus 로고
    • Selective in vitro labeling of white blood cells using 99mTc-labeled liposomes
    • Andreopoulos D, Kasi LP, Asimacopoulos PJ, et al. Selective in vitro labeling of white blood cells using 99mTc-labeled liposomes. Nucl Med Biol. 2002;29:185-190.
    • (2002) Nucl Med Biol , vol.29 , pp. 185-190
    • Andreopoulos, D.1    Kasi, L.P.2    Asimacopoulos, P.J.3
  • 52
    • 0035127410 scopus 로고    scopus 로고
    • Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes
    • Harrington KJ, Mohammadtaghi S, Uster PS, et al. Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes. Clin Cancer Res. 2001;7:243-254.
    • (2001) Clin Cancer Res , vol.7 , pp. 243-254
    • Harrington, K.J.1    Mohammadtaghi, S.2    Uster, P.S.3
  • 53
    • 0020654390 scopus 로고
    • Tumor-imaging potential of liposomes loaded with In-111-NTA: Biodistribution in mice
    • Proffitt RT, Williams LE, Presant CA, et al. Tumor-imaging potential of liposomes loaded with In-111-NTA: biodistribution in mice. J Nucl Med. 1983;24:45-51.
    • (1983) J Nucl Med , vol.24 , pp. 45-51
    • Proffitt, R.T.1    Williams, L.E.2    Presant, C.A.3
  • 54
    • 0027532504 scopus 로고
    • Selective MR imaging of labeled human peripheral blood mononuclear cells by liposome mediated incorporation of dextran-magnetite particles
    • Bulte JW, Ma LD, Magin RL, et al. Selective MR imaging of labeled human peripheral blood mononuclear cells by liposome mediated incorporation of dextran-magnetite particles. Magn Reson Med. 1993;29:32-37.
    • (1993) Magn Reson Med , vol.29 , pp. 32-37
    • Bulte, J.W.1    Ma, L.D.2    Magin, R.L.3
  • 55
    • 23044472885 scopus 로고    scopus 로고
    • Generation of superparamagnetic liposomes revealed as highly efficient MRI contrast agents for in vivo imaging
    • Martina MS, Fortin JP, Menager C, et al. Generation of superparamagnetic liposomes revealed as highly efficient MRI contrast agents for in vivo imaging. J Am Chem Soc. 2005;127:10676-10685.
    • (2005) J Am Chem Soc , vol.127 , pp. 10676-10685
    • Martina, M.S.1    Fortin, J.P.2    Menager, C.3
  • 57
    • 0036707316 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug delivery and targeting
    • Hans ML, Lowman AM. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci. 2002;6:319-327. '
    • (2002) Curr Opin Solid State Mater Sci , vol.6 , pp. 319-327
    • Hans, M.L.1    Lowman, A.M.2
  • 59
    • 0027957863 scopus 로고
    • Dendrimer-based metal chelates: A new class of magnetic resonance imaging contrast agents
    • Wiener EC, Brechbiel MW, Brothers H, et al. Dendrimer-based metal chelates: a new class of magnetic resonance imaging contrast agents. Magn Reson Med. 1994;31:1-8.
    • (1994) Magn Reson Med , vol.31 , pp. 1-8
    • Wiener, E.C.1    Brechbiel, M.W.2    Brothers, H.3
  • 62
    • 0035342007 scopus 로고    scopus 로고
    • Esfand R, Tomalia DA. Poly(amidoamine) (PAMAM) dendrimers from biomimicry to drug delivery and biomedical applications. Drug Discov Today. 200 1;6:427-436.
    • Esfand R, Tomalia DA. Poly(amidoamine) (PAMAM) dendrimers from biomimicry to drug delivery and biomedical applications. Drug Discov Today. 200 1;6:427-436.
  • 63
  • 64
    • 0035229874 scopus 로고    scopus 로고
    • Dendrimers: Properties and applications
    • Klajnert B, Bryszewska M. Dendrimers: properties and applications. Acta Biochim Pol. 2001;48:199-208.
    • (2001) Acta Biochim Pol , vol.48 , pp. 199-208
    • Klajnert, B.1    Bryszewska, M.2
  • 65
    • 0032637389 scopus 로고    scopus 로고
    • Water-soluble dendrimer-poly(ethylene glycol) starlike conjugates as potential drug carriers
    • Liu MJ, Kono K, Frechet JMJ. Water-soluble dendrimer-poly(ethylene glycol) starlike conjugates as potential drug carriers. J Polym Sci A. 2000;37:3492-3503.
    • (2000) J Polym Sci A , vol.37 , pp. 3492-3503
    • Liu, M.J.1    Kono, K.2    Frechet, J.M.J.3
  • 66
    • 0033657796 scopus 로고    scopus 로고
    • Synthesis of polyamidoaminedendrimers having poly(ethyleneglycol) grafts and their ability to encapsulate anticaner drugs
    • Kojima C, Kono K, Maruyama K, Takagishi T. Synthesis of polyamidoaminedendrimers having poly(ethyleneglycol) grafts and their ability to encapsulate anticaner drugs. Bioconjugate Chem. 2000;11:910-917.
    • (2000) Bioconjugate Chem , vol.11 , pp. 910-917
    • Kojima, C.1    Kono, K.2    Maruyama, K.3    Takagishi, T.4
  • 68
    • 0037161405 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery
    • Luo D, Haverstick K, Belcheva N, Han E, Saltzman WM. Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery. Macromolecules. 2002;35:3456-3462.
    • (2002) Macromolecules , vol.35 , pp. 3456-3462
    • Luo, D.1    Haverstick, K.2    Belcheva, N.3    Han, E.4    Saltzman, W.M.5
  • 69
    • 0036183447 scopus 로고    scopus 로고
    • Gene transfer into eukaryotic cells using activated polyamidoamine dendrimers
    • Dennig J, Duncan E. Gene transfer into eukaryotic cells using activated polyamidoamine dendrimers. J Biotechnol. 2002;90:339-347.
    • (2002) J Biotechnol , vol.90 , pp. 339-347
    • Dennig, J.1    Duncan, E.2
  • 70
    • 0000972145 scopus 로고    scopus 로고
    • In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates
    • Yoo HS, Lee KH, Oh JE, Park TG. In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates. J Control Release. 2000;68:419-431.
    • (2000) J Control Release , vol.68 , pp. 419-431
    • Yoo, H.S.1    Lee, K.H.2    Oh, J.E.3    Park, T.G.4
  • 71
    • 0032892747 scopus 로고    scopus 로고
    • Evaluation of the in vivo biodistribution of indium-111 and yttrium-88 labeled dendrimer-1B4M-DTPA and its conjugation with anti-Tac monoclonal antibody
    • Kobayashi H, Wu C, Kim MY, Paik CH, Carrasquillo JA, Brechbiel MW. Evaluation of the in vivo biodistribution of indium-111 and yttrium-88 labeled dendrimer-1B4M-DTPA and its conjugation with anti-Tac monoclonal antibody. Bioconjug Chem. 1999;10:103-111.
    • (1999) Bioconjug Chem , vol.10 , pp. 103-111
    • Kobayashi, H.1    Wu, C.2    Kim, M.Y.3    Paik, C.H.4    Carrasquillo, J.A.5    Brechbiel, M.W.6
  • 73
    • 23944435903 scopus 로고    scopus 로고
    • PAMAM dendrimer based macromolecules as improved contrast agents
    • Venditto VJ, Regino CA, Brechbiel MW. PAMAM dendrimer based macromolecules as improved contrast agents. Mol Pharm. 2005;2:302-311.
    • (2005) Mol Pharm , vol.2 , pp. 302-311
    • Venditto, V.J.1    Regino, C.A.2    Brechbiel, M.W.3
  • 74
    • 0142074730 scopus 로고    scopus 로고
    • Folic acid-conjugated nanostructured materials designed for cancer cell targeting
    • Pan D, Turner JL, Wooley KL. Folic acid-conjugated nanostructured materials designed for cancer cell targeting. Chem Commun (Camb). 2003; 19:2400-2401.
    • (2003) Chem Commun (Camb) , vol.19 , pp. 2400-2401
    • Pan, D.1    Turner, J.L.2    Wooley, K.L.3
  • 75
    • 0034075129 scopus 로고    scopus 로고
    • Recognition of human colon cancer by T cells transduced with a chimeric receptor gene
    • Daly T, Royal RE, Kershaw MH, et al. Recognition of human colon cancer by T cells transduced with a chimeric receptor gene. Cancer Gene Ther. 2000;7:284-291.
    • (2000) Cancer Gene Ther , vol.7 , pp. 284-291
    • Daly, T.1    Royal, R.E.2    Kershaw, M.H.3
  • 77
    • 0037436032 scopus 로고    scopus 로고
    • Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid
    • Wiwattanapatapee R, Lomlim L, Saramunee K. Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid. J Control Release. 2003;88:1-9.
    • (2003) J Control Release , vol.88 , pp. 1-9
    • Wiwattanapatapee, R.1    Lomlim, L.2    Saramunee, K.3
  • 78
    • 34250690091 scopus 로고    scopus 로고
    • A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells
    • In press
    • Fahmy T, Schneck J, Saltzman W. A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. Nanomedicine. In press.
    • Nanomedicine
    • Fahmy, T.1    Schneck, J.2    Saltzman, W.3
  • 79
    • 0031890618 scopus 로고    scopus 로고
    • Synthesis and characterization of polymer-(multi)-peptide conjugates for control of specific cell aggregation
    • Belcheva N, Baldwin SP, Saltzman WM. Synthesis and characterization of polymer-(multi)-peptide conjugates for control of specific cell aggregation. J Biomater Sci Polym Ed. 1998;9:207-226.
    • (1998) J Biomater Sci Polym Ed , vol.9 , pp. 207-226
    • Belcheva, N.1    Baldwin, S.P.2    Saltzman, W.M.3
  • 80
    • 0033230001 scopus 로고    scopus 로고
    • Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate
    • Belcheva N, Woodrow-Mumford K, Mahoney MJ, Saltzman WM. Synthesis and biological activity of polyethylene glycol-mouse nerve growth factor conjugate. Bioconjug Chem. 1999;10:932-937.
    • (1999) Bioconjug Chem , vol.10 , pp. 932-937
    • Belcheva, N.1    Woodrow-Mumford, K.2    Mahoney, M.J.3    Saltzman, W.M.4
  • 81
    • 0027253357 scopus 로고
    • The conjugation of proteins with polyethylene glycol and other polymers altering properties of proteins to enhance their therapeutic potential
    • Katre NV. The conjugation of proteins with polyethylene glycol and other polymers altering properties of proteins to enhance their therapeutic potential. Adv Drug Deltv Rev. 1993;10:91-114.
    • (1993) Adv Drug Deltv Rev , vol.10 , pp. 91-114
    • Katre, N.V.1
  • 82
    • 10644287589 scopus 로고    scopus 로고
    • Dendrimer-based nanosized MRI contrast agents
    • Kobayashi H, Brechbiel MW. Dendrimer-based nanosized MRI contrast agents. Curr Pharm Biotechnol. 2004;5:539-549.
    • (2004) Curr Pharm Biotechnol , vol.5 , pp. 539-549
    • Kobayashi, H.1    Brechbiel, M.W.2
  • 83
    • 28744441712 scopus 로고    scopus 로고
    • Nano-sized MRI contrast agents with dendrimer cores
    • Kobayashi H, Brechbiel MW. Nano-sized MRI contrast agents with dendrimer cores. Adv Drug Deliv Rev. 2005;57:2271-2286.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 2271-2286
    • Kobayashi, H.1    Brechbiel, M.W.2
  • 84
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Anderson JM, Shive MS. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev. 1997;28:5-24.
    • (1997) Adv Drug Deliv Rev , vol.28 , pp. 5-24
    • Anderson, J.M.1    Shive, M.S.2
  • 85
    • 0017317645 scopus 로고
    • Polymers for the sustained release of proteins and other macromolecules
    • Langer R, Folkman J. Polymers for the sustained release of proteins and other macromolecules. Nature. 1976;263:797-800.
    • (1976) Nature , vol.263 , pp. 797-800
    • Langer, R.1    Folkman, J.2
  • 87
    • 0035997342 scopus 로고    scopus 로고
    • Sustained release chemotherapeutic microspheres provide superior efficacy over systemic therapy and local bolus infusions
    • Emerich DF, Snodgrass P, Lafreniere D, et al. Sustained release chemotherapeutic microspheres provide superior efficacy over systemic therapy and local bolus infusions. Pharm Res. 2002;19:1052-1060.
    • (2002) Pharm Res , vol.19 , pp. 1052-1060
    • Emerich, D.F.1    Snodgrass, P.2    Lafreniere, D.3
  • 88
    • 0029875854 scopus 로고    scopus 로고
    • On the mechanism of action of doxorubicin encapsulation in nanospheres for the reversal of multidrug resistance
    • Hu YP, Jarillon S, Dubernet C, Couvreur P, Robert J. On the mechanism of action of doxorubicin encapsulation in nanospheres for the reversal of multidrug resistance. Cancer Chemother Pharmacol. 1996;37:556-560.
    • (1996) Cancer Chemother Pharmacol , vol.37 , pp. 556-560
    • Hu, Y.P.1    Jarillon, S.2    Dubernet, C.3    Couvreur, P.4    Robert, J.5
  • 89
    • 14744290856 scopus 로고    scopus 로고
    • MR imaging of biodegradable polymeric microparticles: A potential method of monitoring local drug delivery
    • Chen HH, Le Visage C, Qiu B. et al. MR imaging of biodegradable polymeric microparticles: a potential method of monitoring local drug delivery. Magn Reson Med. 2005;53:614-620.
    • (2005) Magn Reson Med , vol.53 , pp. 614-620
    • Chen, H.H.1    Le Visage, C.2    Qiu, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.