Agonists activate Gi1α or Gi2α fused to the human mu opioid receptor differently

Journal of Neurochemistry

Volumn 81, Issue 6, 2002, Pages 1372-1382

  Massotte, Dominique ^a,c   Brillet, Karl ^a   Kieffer, Brigitte L ^a   Milligan, Graeme ^b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

ERK MAPK; Fusion protein; G protein coupled receptor; Gi proteins; Mu opioid receptor

Indexed keywords

BETA ENDORPHIN; BUPRENORPHINE; CYCLIC AMP; DERMORPHIN; DIPRENORPHINE; DYNORPHIN A; ENDOMORPHIN 1; ENDOMORPHIN 2; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 1ALPHA; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 2ALPHA; LIGAND; METENKEPHALIN; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; PERTUSSIS TOXIN; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; GNAI2 PROTEIN, HUMAN; ONCOPROTEIN;

ARTICLE; CELL KINETICS; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFICACY; DRUG RECEPTOR BINDING; ENZYME PHOSPHORYLATION; GENE CONSTRUCT; GENE FUSION; HUMAN; HUMAN CELL; NEUROMODULATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR UPREGULATION; REPORTER GENE; SIGNAL TRANSDUCTION; WILD TYPE; CELL LINE; DRUG POTENTIATION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ARTIFICIAL GENE FUSION; CELL LINE; GENES, REPORTER; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RECEPTORS, OPIOID, MU;

EID: 0035983601     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00946.x     Document Type: Article

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