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Volumn 11, Issue 14, 2004, Pages 1146-1154

Multi-subtype gp160 DNA immunization induces broadly neutralizing anti-HIV antibodies

Author keywords

Antibody neutralization; DNA immunization; GM CSF; gp160; HIV 1

Indexed keywords

ALUMINUM HYDROXIDE; DNA VACCINE; EPITOPE; GLYCOPROTEIN GP 160; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY; OLIGODEOXYNUCLEOTIDE; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; VIRUS ENVELOPE PROTEIN; IMMUNOGLOBULIN G; VIRUS ANTIBODY;

EID: 4243109693     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302275     Document Type: Article
Times cited : (43)

References (52)
  • 1
    • 4344695558 scopus 로고    scopus 로고
    • UNAIDS/WHO. AIDS epidemic update: December 2003. UNAIDS/WHO, (www.unaids.org)
    • UNAIDS/WHO. AIDS epidemic update: December 2003. UNAIDS/WHO, (www.unaids.org) 2003.
    • (2003)
  • 2
    • 0034988459 scopus 로고    scopus 로고
    • HIV in Europe - A growing threat
    • Wahren B. HIV in Europe - a growing threat. J Clin Virol 2001; 21: 171-173.
    • (2001) J. Clin. Virol. , vol.21 , pp. 171-173
    • Wahren, B.1
  • 3
    • 0032906836 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 subtypes differ in disease progression
    • Kanki PJ et al. Human immunodeficiency virus type 1 subtypes differ in disease progression. J Infect Dis 1999; 179: 68-73.
    • (1999) J. Infect. Dis. , vol.179 , pp. 68-73
    • Kanki, P.J.1
  • 4
    • 0038638590 scopus 로고    scopus 로고
    • HIV vaccines 1983-2003
    • McMichael AJ, Hanke T. HIV vaccines 1983-2003. Nat Med 2003; 9: 874-880.
    • (2003) Nat. Med. , vol.9 , pp. 874-880
    • McMichael, A.J.1    Hanke, T.2
  • 5
    • 0037029939 scopus 로고    scopus 로고
    • HIV vaccine strategies
    • Nabel GJ. HIV vaccine strategies. Vaccine 2002; 20: 1945-1947.
    • (2002) Vaccine , vol.20 , pp. 1945-1947
    • Nabel, G.J.1
  • 6
    • 28644444280 scopus 로고    scopus 로고
    • VaxGen Announces Results of its Phase III HIV Vaccine Trial in Thailand: Vaccine Fails to Meet Endpoints
    • Announces Results of its Phase III HIV Vaccine Trial in Thailand: Vaccine Fails to Meet Endpoints, http://www.vaxgen.com/pressroom/index.html>
    • Berman PW VaxGen Announces Results of its Phase III HIV Vaccine Trial in Thailand: Vaccine Fails to Meet Endpoints, http://www.vaxgen.com/pressroom/index.htmlVaxGen Announces Results of its Phase III HIV Vaccine Trial in Thailand: Vaccine Fails to Meet Endpoints, http://www.vaxgen.com/pressroom/index.html> 2003.
    • (2003)
    • Berman, P.W.1
  • 7
    • 0033826855 scopus 로고    scopus 로고
    • Design and construction of an experimental HIV-1 vaccine for a year - 2000 clinical trial in Kenya
    • Hanke T, McMichael AJ. Design and construction of an experimental HIV-1 vaccine for a year - 2000 clinical trial in Kenya. Nat Med 2000; 6: 951-955.
    • (2000) Nat. Med. , vol.6 , pp. 951-955
    • Hanke, T.1    McMichael, A.J.2
  • 8
    • 0037122719 scopus 로고    scopus 로고
    • Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity
    • Shiver JW et al. Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 2002; 415: 331-335.
    • (2002) Nature , vol.415 , pp. 331-335
    • Shiver, J.W.1
  • 9
    • 0033566813 scopus 로고    scopus 로고
    • Immune responses in asymptomatic HIV-1-infected patients after HIV-DNA immunization followed by highly active antiretroviral treatment
    • Calarota SA et al. Immune responses in asymptomatic HIV-1-infected patients after HIV-DNA immunization followed by highly active antiretroviral treatment. J Immunol 1999; 163: 2330-2338.
    • (1999) J. Immunol. , vol.163 , pp. 2330-2338
    • Calarota, S.A.1
  • 10
    • 0033811377 scopus 로고    scopus 로고
    • Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids
    • Boyer JD et al. Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids. AIDS 2000; 14: 1515-1522.
    • (2000) AIDS , vol.14 , pp. 1515-1522
    • Boyer, J.D.1
  • 11
    • 4344602052 scopus 로고    scopus 로고
    • Diversity considerations in HIV-1 vaccine selection
    • Gaschen B. Diversity considerations in HIV-1 vaccine selection. Science 2003; 299: 1515-1518.
    • (2003) Science , vol.299 , pp. 1515-1518
    • Gaschen, B.1
  • 12
    • 0034978733 scopus 로고    scopus 로고
    • Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development
    • Moore JP, Parren PW, Burton DR. Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development. J Virol 2001; 75: 5721-5729.
    • (2001) J. Virol. , vol.75 , pp. 5721-5729
    • Moore, J.P.1    Parren, P.W.2    Burton, D.R.3
  • 13
    • 0141680277 scopus 로고    scopus 로고
    • Novel engineered HIV-1 East African Clade-A gp160 plasmid construct induces strong humoral and cell-mediated immune responses in vivo
    • Muthumani K ZD et al. Novel engineered HIV-1 East African Clade-A gp160 plasmid construct induces strong humoral and cell-mediated immune responses in vivo. Virology 2003; 15: 134-146.
    • (2003) Virology , vol.15 , pp. 134-146
    • Muthumani, K.Z.D.1
  • 14
    • 0037122796 scopus 로고    scopus 로고
    • Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphoctes
    • Barouch DH et al. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphoctes. Nature 2002; 415: 335-339.
    • (2002) Nature , vol.415 , pp. 335-339
    • Barouch, D.H.1
  • 15
    • 0033766645 scopus 로고    scopus 로고
    • Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination
    • Barouch DH et al. Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 2000; 290: 486-492.
    • (2000) Science , vol.290 , pp. 486-492
    • Barouch, D.H.1
  • 16
    • 0037080035 scopus 로고    scopus 로고
    • Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CFE
    • Barouch DH et al. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CFE. J Immunol 2002; 168: 562-568.
    • (2002) J. Immunol. , vol.168 , pp. 562-568
    • Barouch, D.H.1
  • 17
    • 0033104744 scopus 로고    scopus 로고
    • IL-12 gene as a DNA vaccine adjuvant in a herpes mouse model: IL-12 enhances Th1-type CD4+ T cell-mediated protective immunity against herpes simplex virus-2 challenge
    • Sin JI et al. IL-12 gene as a DNA vaccine adjuvant in a herpes mouse model: IL-12 enhances Th1-type CD4+ T cell-mediated protective immunity against herpes simplex virus-2 challenge. J Immunol 1999; 162: 2912-2921.
    • (1999) J. Immunol. , vol.162 , pp. 2912-2921
    • Sin, J.I.1
  • 18
    • 0033823762 scopus 로고    scopus 로고
    • Interleukin 7 can enhance antigen-specific cytotoxic-T-lymphocyte and/or Th2-type immune responses in vivo
    • Sin JI et al. Interleukin 7 can enhance antigen-specific cytotoxic-T-lymphocyte and/or Th2-type immune responses in vivo. Clin Diagn Lab Immunol 2000; 7: 751-758.
    • (2000) Clin. Diagn. Lab. Immunol. , vol.7 , pp. 751-758
    • Sin, J.I.1
  • 19
    • 19244367476 scopus 로고    scopus 로고
    • Rectal and vaginal immunization with a macromolecular multicomponent peptide vaccine candidate for HIV-1 infection induces HIV-specific protective immune responses
    • Kato H et al. Rectal and vaginal immunization with a macromolecular multicomponent peptide vaccine candidate for HIV-1 infection induces HIV-specific protective immune responses. Vaccine 2000; 18: 1151-1160.
    • (2000) Vaccine , vol.18 , pp. 1151-1160
    • Kato, H.1
  • 20
    • 0032959691 scopus 로고    scopus 로고
    • Cytokine molecular adjuvants modulate immune responses induced by DNA vaccine constructs for HIV-1 and SIV
    • Kim JJ et al. Cytokine molecular adjuvants modulate immune responses induced by DNA vaccine constructs for HIV-1 and SIV. J Interferon Cytokine Res 1999; 19: 77-84.
    • (1999) J. Interferon. Cytokine. Res. , vol.19 , pp. 77-84
    • Kim, J.J.1
  • 21
    • 0036132847 scopus 로고    scopus 로고
    • Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice
    • Moore AC, Kong WP, Chakrabarti BK, Nabel GJ. Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice. J Virol 2002; 76: 243-250.
    • (2002) J. Virol. , vol.76 , pp. 243-250
    • Moore, A.C.1    Kong, W.P.2    Chakrabarti, B.K.3    Nabel, G.J.4
  • 22
    • 0034528144 scopus 로고    scopus 로고
    • Induction of immune responses and break of tolerance by DNA against the HIV-1 coreceptor CCR5 but no protection from SIVsm challenge
    • Zuber B et al. Induction of immune responses and break of tolerance by DNA against the HIV-1 coreceptor CCR5 but no protection from SIVsm challenge. Virology 2000; 278: 400-411.
    • (2000) Virology , vol.278 , pp. 400-411
    • Zuber, B.1
  • 23
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis HL et al. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol 1998; 160: 870-876.
    • (1998) J. Immunol. , vol.160 , pp. 870-876
    • Davis, H.L.1
  • 24
    • 0037032060 scopus 로고    scopus 로고
    • A novel potent strategy for induction of immunity to HIV-1 reverse transcriptase in primates
    • Zuber B, Mäkitalo B, Zuber AK, Wahren B. A novel potent strategy for induction of immunity to HIV-1 reverse transcriptase in primates. AIDS 2002; 16: 1839-1840.
    • (2002) AIDS , vol.16 , pp. 1839-1840
    • Zuber, B.1    Mäkitalo, B.2    Zuber, A.K.3    Wahren, B.4
  • 25
    • 0032944291 scopus 로고    scopus 로고
    • Immunostimulatory CpG motifs trigger a T helper-1 immune response to human immunodeficiency virus type-1 (HIV-1) gp 160 envelope proteins
    • Deml L et al. Immunostimulatory CpG motifs trigger a T helper-1 immune response to human immunodeficiency virus type-1 (HIV-1) gp 160 envelope proteins. Clin Chem Lab Med 1999; 37: 199-204.
    • (1999) Clin. Chem. Lab. Med. , vol.37 , pp. 199-204
    • Deml, L.1
  • 26
    • 0037726807 scopus 로고    scopus 로고
    • A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant
    • Halperin SAVNG et al. A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant. Vaccine 2003; 21: 2461-2467.
    • (2003) Vaccine , vol.21 , pp. 2461-2467
    • Halperin, S.A.V.N.G.1
  • 27
    • 0037128135 scopus 로고    scopus 로고
    • Parenteral and mucosal prime-boost immunization strategies in mice with hepatitis B surface antigen and CpG DNA
    • McCluskie MJ, Weeratna RD, Payette PJ, Davis HL. Parenteral and mucosal prime-boost immunization strategies in mice with hepatitis B surface antigen and CpG DNA. FEMS Immunol Med Microbiol 2002; 32: 179-185.
    • (2002) FEMS Immunol. Med. Microbiol. , vol.32 , pp. 179-185
    • McCluskie, M.J.1    Weeratna, R.D.2    Payette, P.J.3    Davis, H.L.4
  • 28
    • 0036720793 scopus 로고    scopus 로고
    • Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades
    • Gorny MK et al. Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades. J Virol 2002; 76: 9035-9045.
    • (2002) J. Virol. , vol.76 , pp. 9035-9045
    • Gorny, M.K.1
  • 29
    • 0036434328 scopus 로고    scopus 로고
    • Enhanced immune responses after DNA vaccination with combined envelope genes from different HIV-1 subtypes
    • Ljungberg K et al. Enhanced immune responses after DNA vaccination with combined envelope genes from different HIV-1 subtypes. Virology 2002; 302: 44-57.
    • (2002) Virology , vol.302 , pp. 44-57
    • Ljungberg, K.1
  • 30
    • 0036096976 scopus 로고    scopus 로고
    • Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization
    • Chakrabarti BK et al. Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization. J Virol 2002; 76: 5357-5368.
    • (2002) J. Virol. , vol.76 , pp. 5357-5368
    • Chakrabarti, B.K.1
  • 31
    • 0031569963 scopus 로고    scopus 로고
    • Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines
    • Iwasaki A et al. Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines. J Immunol 1997; 158: 4591-4601.
    • (1997) J. Immunol. , vol.158 , pp. 4591-4601
    • Iwasaki, A.1
  • 32
    • 0034654261 scopus 로고    scopus 로고
    • The timing of GM-CSF expression plasmid administration influences the Thl/Th2 response induced by an HIV-1-specific DNA vaccine
    • Kusakabe K et al. The timing of GM-CSF expression plasmid administration influences the Thl/Th2 response induced by an HIV-1-specific DNA vaccine. J Immunol 2000; 164: 3102-3111.
    • (2000) J. Immunol. , vol.164 , pp. 3102-3111
    • Kusakabe, K.1
  • 33
    • 0031093543 scopus 로고    scopus 로고
    • Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization
    • Feltquate DM, Heaney S, Webster RG, Robinson HL. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J Immunol 1997; 158: 2278-2284.
    • (1997) J. Immunol. , vol.158 , pp. 2278-2284
    • Feltquate, D.M.1    Heaney, S.2    Webster, R.G.3    Robinson, H.L.4
  • 34
    • 0037024759 scopus 로고    scopus 로고
    • Phase I/II trial of HIV-1 hyperimmune globulin for the prevention of HIV-1 vertical transmission in Uganda
    • Guay LA et al. Phase I/II trial of HIV-1 hyperimmune globulin for the prevention of HIV-1 vertical transmission in Uganda. AIDS 2002; 16: 1391-1400.
    • (2002) AIDS , vol.16 , pp. 1391-1400
    • Guay, L.A.1
  • 36
    • 0027284896 scopus 로고
    • Gene inoculation generates immune responses against human immunodeficiency virus type 1
    • Wang B et al. Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1993; 90: 4156-4160.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4156-4160
    • Wang, B.1
  • 37
    • 0032581491 scopus 로고    scopus 로고
    • Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
    • Klenerman P, Zinkernagel RM. Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature 1998; 394: 482-485.
    • (1998) Nature , vol.394 , pp. 482-485
    • Klenerman, P.1    Zinkernagel, R.M.2
  • 38
    • 0031695977 scopus 로고    scopus 로고
    • Role of preimmunization virus sequences in cellular immunity in HIV-infected patients during HIV type 1 MN recombinant gp160 immunization
    • Kundu SK et al. Role of preimmunization virus sequences in cellular immunity in HIV-infected patients during HIV type 1 MN recombinant gp160 immunization. AIDS Res Hum Retroviruses 1998; 14: 1669-1678.
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 1669-1678
    • Kundu, S.K.1
  • 39
    • 0036686398 scopus 로고    scopus 로고
    • CpG-DNA aided cross-presentation of soluble antigens by dendritic cells
    • Maurer T et al. CpG-DNA aided cross-presentation of soluble antigens by dendritic cells. Eur J Immunol 2002; 32: 2356-2364.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2356-2364
    • Maurer, T.1
  • 40
    • 0032533269 scopus 로고    scopus 로고
    • Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor
    • Liu HM et al. Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor. Blood 1998; 92: 3730-3736.
    • (1998) Blood , vol.92 , pp. 3730-3736
    • Liu, H.M.1
  • 41
    • 0034807171 scopus 로고    scopus 로고
    • Induction of antigen-specific Th1-biased immune responses by plasmid DNA in schistosoma-infected mice with a preexistent dominant Th2 immune profile
    • Ayash-Rashkovsky M et al. Induction of antigen-specific Th1-biased immune responses by plasmid DNA in schistosoma-infected mice with a preexistent dominant Th2 immune profile. Biochem Biophys Res Commun 2001; 282: 1169-1176.
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 1169-1176
    • Ayash-Rashkovsky, M.1
  • 43
    • 0032538597 scopus 로고    scopus 로고
    • Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
    • Wang R et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 1998; 282: 476-480.
    • (1998) Science , vol.282 , pp. 476-480
    • Wang, R.1
  • 44
    • 17444435761 scopus 로고    scopus 로고
    • Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients
    • Calarota S et al. Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients. Lancet 1998; 351: 1320-1325.
    • (1998) Lancet , vol.351 , pp. 1320-1325
    • Calarota, S.1
  • 45
    • 0005457558 scopus 로고    scopus 로고
    • First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: Safety and host response
    • MacGregor RR et al. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response. J Infect Dis 1998; 178: 92-100.
    • (1998) J. Infect. Dis. , vol.178 , pp. 92-100
    • MacGregor, R.R.1
  • 46
    • 0035947281 scopus 로고    scopus 로고
    • Interactions of single and combined human immunodeficiency virus type 1 (HIV-1) DNA vaccines
    • Kjerrström A et al. Interactions of single and combined human immunodeficiency virus type 1 (HIV-1) DNA vaccines. Virology 2001; 284: 46-61.
    • (2001) Virology , vol.284 , pp. 46-61
    • Kjerrström, A.1
  • 47
    • 0025092328 scopus 로고
    • Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120
    • Akerblom L et al. Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120. AIDS 1990; 4: 953-960.
    • (1990) AIDS , vol.4 , pp. 953-960
    • Akerblom, L.1
  • 48
    • 0026536582 scopus 로고
    • Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins
    • Broliden PA et al. Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins. Proc Natl Acad Sci USA 1992; 89: 461-465.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 461-465
    • Broliden, P.A.1
  • 49
    • 0029921050 scopus 로고    scopus 로고
    • Immunodominant glycoprotein 41 epitope identified by seroreactivity in HIV type 1-infected individuals
    • Calarota S et al. Immunodominant glycoprotein 41 epitope identified by seroreactivity in HIV type 1-infected individuals. AIDS Res Hum Retroviruses 1996; 12: 705-713.
    • (1996) AIDS. Res. Hum. Retroviruses , vol.12 , pp. 705-713
    • Calarota, S.1
  • 50
    • 0007253020 scopus 로고
    • Detection of antibodies to human T-lymphotropic virus type III by using a synthetic pepticle of 21 amino acid residues corresponding to a highly antigenic segment of gp4l envelope protein
    • Wang JJ, Steel S, Wisniewolski R, Wang CY. Detection of antibodies to human T-lymphotropic virus type III by using a synthetic pepticle of 21 amino acid residues corresponding to a highly antigenic segment of gp4l envelope protein. Proc Natl Acad Sci USA 1986; 83: 6159-6163.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6159-6163
    • Wang, J.J.1    Steel, S.2    Wisniewolski, R.3    Wang, C.Y.4
  • 51
    • 0028170085 scopus 로고
    • Immunological and virological interactions in patients receiving passive immunotherapy with HIV-1 neutralizing monoclonal antibodies
    • Hinkula J et al. Immunological and virological interactions in patients receiving passive immunotherapy with HIV-1 neutralizing monoclonal antibodies. J Acquir Immune Defic Syndr 1994; 7: 940-951.
    • (1994) J. Acquir. Immune. Defic. Syndr. , vol.7 , pp. 940-951
    • Hinkula, J.1
  • 52
    • 0034697215 scopus 로고    scopus 로고
    • Mapping of B-cell epitopes in rabbits immunised with various gag antigens for the production of HIV-1 gag capture ELISA reagents
    • Devito C, Levi M, Broliden K, Hinkula J. Mapping of B-cell epitopes in rabbits immunised with various gag antigens for the production of HIV-1 gag capture ELISA reagents. J Immunol Methods 2000; 238: 69-80.
    • (2000) J. Immunol. Methods , vol.238 , pp. 69-80
    • Devito, C.1    Levi, M.2    Broliden, K.3    Hinkula, J.4


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