Enhanced immune responses after DNA vaccination with combined envelope genes from different HIV-1 subtypes

Virology

Volumn 302, Issue 1, 2002, Pages 44-57

  Ljungberg, Karl ^a   Rollman, Erik ^a   Eriksson, Lars ^a   Hinkula, Jorma ^a   Wahren, Britta ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

DNA vaccine; Gp160; HIV 1

Indexed keywords

DNA VACCINE;

ARTICLE; CONTROLLED STUDY; ENVELOPE GENE; GENE; GP 160 GENE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; VACCINATION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036434328     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2002.1547     Document Type: Article

References (49)

1. Abacioglu, Y. H., Fouts, T. R., Laman, J. D., Claassen, E., Pincus, S. H., Moore, J. P., Roby, C. A., Kamin-Lewis, R., and Lewis, G. K. (1994). Epitope mapping and topology of baculovirus-expressed HIV-1 gp160 determined with a panel of murine monoclonal antibodies. AIDS Res. Hum. Retroviruses 10(4), 371-381.
2. Åkerblom, L., Hinkula, J., Broliden, P. A., Mäkitalo, B., Fridberger, T., Rosen, J., Villacres-Eriksson, M., Morein, B., and Wahren, B. (1990). Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120. AIDS 4(10), 953-960.
3. Amara, R. R., Villinger, F., Altman, J. D., Lydy, S. L., O'Neil, S. P., Staprans, S. I., Montefiori, D. C., Xu, Y., Herndon, J. G., Wyatt, L. S., Candido, M. A., Kozyr, N. L., Earl, P. L., Smith, J. M., Ma, H. L., Grimm, B. D., Hulsey, M. L., Miller, J., McClure, H. M., McNicholl, J. M., Moss, B., and Robinson, H. L. (2001). Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 292(5514), 69-74.
4. Andäng, M., Hinkula, J., Hotchkiss, G., Larsson, S., Britton, S., Wong-Staal, F., Wahren, B., and Ährlund-Richter, L. (1999). Dose-response resistance to HIV-1/MuLV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model. Proc. Natl. Acad. Sci. USA 96(22), 12749-12753.
5. Attanasio, R., Pehler, K., and Scinicariello, F. (1997). DNA-based immunization induces anti-CD4 antibodies directed primarily to native epitopes. FEMS Immunol. Med. Microbiol. 17(4), 207-215.
6. Barouch, D. H., Craiu, A., Santra, S., Egan, M. A., Schmitz, J. E., Kuroda, M. J., Fu, T. M., Nam, J. H., Wyatt, L. S., Lifton, M. A., Krivulka, G. R., Nickerson, C. E., Lord, C. I., Moss, B., Lewis, M. G., Hirsch, V. M., Shiver, J. W., and Letvin, N. L. (2001). Elicitation of high-frequency cytotoxic T-lymphocyte responses against both dominant and subdominant simian-human immunodeficiency virus epitopes by DNA vaccination of rhesus monkeys. J. Virol. 75(5), 2462-2467.
7. Berman, P. W., Huang, W., Riddle, L., Gray, A. M., Wrin, T., Vennari, J., Johnson, A., Klaussen, M., Prashad, H., Kohne, C., DeWit, C., and Gregory, T. J. (1999). Development of bivalent (B/E) vaccines able to neutralize CCR5-dependent viruses from the United States and Thailand. Virology 265(1), 1-9.
8. Bubeck, P., Winkler, M., and Bautsch, W. (1993). Rapid cloning by homologous recombination in vivo. Nucleic Acids Res. 21(15), 3601-3602.
9. Calarota, S. A., Leandersson, A. C., Bratt, G., Hinkula, J., Klinman, D. M., Weinhold, K. J., Sandström, E., and Wahren, B. (1999). Immune responses in asymptomatic HIV-1-infected patients after HIV-DNA immunization followed by highly active antiretroviral treatment. J. Immunol. 163(4), 2330-2338.
10. Chun, T. W., Davey, R. T., Jr., Engel, D., Lane, H. C., and Fauci, A. S. (1999). Re-emergence of HIV after stopping therapy. Nature 401(6756), 874-875.
11. Chun, T. W., and Fauci, A. S. (1999). Latent reservoirs of HIV: Obstacles to the eradication of virus. Proc. Natl. Acad. Sci. USA 96(20), 10958-10961.
12. Davis, H. L., Weeratna, R., Waldschmidt, T. J., Tygrett, L., Schorr, J., Krieg, A. M., and Weeranta, R. (1998). CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J. Immunol. 160(2), 870-876.
13. Deck, R. R., DeWitt, C. M., Donnelly, J. J., Liu, M. A., and Ulmer, J. B. (1997). Characterization of humoral immune responses induced by an influenza hemagglutinin DNA vaccine. Vaccine 15(1), 71-78.
14. Devito, C., Levi, M., Broliden, K., and Hinkula, J. (2000). Mapping of B-cell epitopes in rabbits immunised with various gag antigens for the production of HIV-1 gag capture ELISA reagents. J. Immunol. Methods 238(1-2), 69-80.
15. Geijtenbeek, T. B., Kwon, D. S., Torensma, R., van Vliet, S. J., van Duijnhoven, G. C., Middel, J., Cornelissen, I. L., Nottet, H. S., Kewal-Ramani, V. N., Littman, D. R., Figdor, C. G., and van Kooyk, Y. (2000). DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100(5), 587-597.
16. Gilljam, G. (1993). Envelope glycoproteins of HIV-1, HIV-2, and SIV purified with Galanthus nivalis agglutinin induce strong immune responses. AIDS Res. Hum. Retroviruses 9(5), 431-438.
17. Hinkula, J., Bratt, G., Gilljam, G., Nordlund, S., Broliden, P. A., Holmberg, V., Olausson-Hansson, E., Albert, J., Sandström, E., and Wahren, B. (1994). Immunological and virological interactions in patients receiving passive immunotherapy with HIV-1 neutralizing monoclonal antibodies. J. Acquir. Immune Defic. Syndr. 7(9), 940-951.
18. Isaguliants, M. G., Petrakova, N. N., Zuber, B., Pokrovskaya, K., Gizatullin, R., Kostyuk, D. A., Kjerrstrom, A., Winberg, G., Kochetkov, S. N., Hinkula, J., and Wahren, B. (2000). DNA-encoding enzymatically active HIV-1 reverse transcriptase, but not the inactive mutant, confers resistance to experimental hiv-1 challenge. Intervirology 43(4-6), 288-293.
19. Ishii, N., Fukushima, J., Kaneko, T., Okada, E., Tani, K., Tanaka, S. I., Hamajima, K., Xin, K. Q., Kawamoto, S., Koff, W., Nishioka, K., Yasuda, T., and Okuda, K. (1997). Cationic liposomes are a strong adjuvant for a DNA vaccine of human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses 13(16), 1421-1428.
20. Krieg, A. M., Yi, A. K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A., and Klinman, D. M. (1995). CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374(6522), 546-549.
21. Kuiken, C., Foley, B., Hahn, B., Marx, P., McCutchan, F., Mellors, J., Mullins, J., Wolinsky, S., Korber, B., Ed. (2000). "Human Retroviruses and AIDS 1999." Los Alamos: Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM.
22. Leandersson, A. C., Gilljam, G., Fredriksson, M., Hinkula, J., Alaeus, A., Lidman, K., Albert, J., Bratt, G., Sandström, E., and Wahren, B. (2000). Cross-reactive T-helper responses in patients infected with different subtypes of human immunodeficiency virus type 1. J. Virol. 74(10), 4888-4890.
23. Levi, M., Ruden, U., Birx, D., Loomis, L., Redfield, R., Lövgren, K., Åkerblom, L., Sandström, E., and Wahren, B. (1993). Effects of adjuvants and multiple antigen peptides on humoral and cellular immune responses to gp160 of HIV-1. J. Acquir. Immune Defic. Syndr. 6(8), 855-864.
24. Ljungberg, K., Wahren, B., Almqvist, J., Hinkula, J., Linde, A., and Win-berg, G. (2000). Effective construction of DNA vaccines against variable influenza genes by homologous recombination. Virology 268(2), 244-250.
25. Lundholm, P., Asakura, Y., Hinkula, J., Lucht, E., and Wahren, B. (1999). Induction of mucosal IgA by a novel jet delivery technique for HIV-1 DNA. Vaccine 17(15-16), 2036-2042.
26. Lusso, P., Di Marzo Veronese, F., Ensoli, B., Franchini, G., Jemma, C., DeRocco, S. E., Kalyanaraman, V. S., and Gallo, R. C. (1990). Expanded HIV-1 cellular tropism by phenotypic mixing with murine endogenous retroviruses. Science 247(4944), 848-852.
27. Moore, J. P., Sattentau, Q. J., Wyatt, R., and Sodroski, J. (1994). Probing the structure of the human immunodeficiency virus surface glyco-protein gp120 with a panel of monoclonal antibodies. J. Virol. 68(1), 469-484.
28. Moulard, M., Chaloin, L., Canarelli, S., Mabrouk, K., Darbon, H., and Challoin, L. (1998). Retroviral envelope glycoprotein processing: Structural investigation of the cleavage site [published erratum appears in Biochemistry 37(27), 9870 (1998)]. Biochemistry 37(13), 4510-4517.
29. Nguyen, D. H., and Hildreth, J. E. (2000). Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J. Virol. 74(7), 3264-3272.
30. Ogg, G. S., Jin, X., Bonhoeffer, S., Dunbar, P. R., Nowak, M. A., Monard, S., Segal, J. P., Cao, Y., Rowland-Jones, S. L., Cerundolo, V., Hurley, A., Markowitz, M., Ho, D. D., Nixon, D. F., and McMichael, A. J. (1998). Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science 279(5359), 2103-2106.
31. Osterhaus, A. D., van Baalen, C. A., Gruters, R. A., Schutten, M., Sie-belink, C. H., Hulskotte, E. G., Tijhaar, E. J., Randall, R. E., van Amerongen, G., Fleuchaus, A., Erfle, V., and Sutter, G. (1999). Vaccination with Rev and Tat against AIDS. Vaccine 17(20-21), 2713-2714.
32. Pett, M. A. (1997). "Nonparametric Statistics for Health Care Research." SAGE Publications, Inc., Thousand Oaks, CA.
33. Putkonen, P., Quesada-Rolander, M., Leandersson, A. C., Schwartz, S., Thorstensson, R., Okuda, K., Wahren, B., and Hinkula, J. (1998). Immune responses but no protection against SHIV by gene-gun delivery of HIV-1 DNA followed by recombinant subunit protein boosts. Virology 250(2), 293-301.
34. Richard, N., Iacampo, S., and Cochrane, A. (1994). HIV-1 Rev is capable of shuttling between the nucleus and cytoplasm. Virology 204(1), 123-131.
35. Robinson, H. L., Hunt, L. A., and Webster, R. G. (1993). Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 11(9), 957-960.
36. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). Strategies for cloning in plasmid vectors. In "Molecular Cloning. A Laboratory Manual." 2nd Ed. (C. Nolan, Ed.), Cold Spring Harbor Laboratory Press, New York.
37. Schmitz, J. E., Kuroda, M. J., Santra, S., Sasseville, V. G., Simon, M. A., Lifton, M. A., Racz, P., Tenner-Racz, K., Dalesandro, M., Scallon, B. J., Ghrayeb, J., Forman, M. A., Montefiori, D. C., Rieber, E. P., Letvin, N. L., and Reimann, K. A. (1999). Control of viremia in simian immunodeficiency virus infection by CD83 lymphocytes. Science 283(5403), 857-860.
38. Shibata, R., Igarashi, T., Haigwood, N., Buckler-White, A., Ogert, R., Ross, W., Willey, R., Cho, M. W., and Martin, M. A. (1999). Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys [see comments]. Nat. Med. 5(2), 204-210.
39. Smith, B. A., Gartner, S., Liu, Y., Perelson, A. S., Stilianakis, N. I., Keele, B. F., Kerkering, T. M., Ferreira-Gonzalez, A., Szakal, A. K., Tew, J. G., and Burton, G. F. (2001). Persistence of infectious HIV on follicular dendritic cells. J. Immunol. 166(1), 690-696.
40. Speck, R. F., Wehrly, K., Platt, E. J., Atchison, R. E., Charo, I. F., Kabat, D., Chesebro, B., and Goldsmith, M. A. (1997). Selective employment of chemokine receptors as human immunodeficiency virus type 1 co-receptors determined by individual amino acids within the envelope V3 loop. J. Virol. 71(9), 7136-7139.
41. Spector, D. H., Wade, E., Wright, D. A., Koval, V., Clark, C., Jaquish, D., and Spector, S. A. (1990). Human immunodeficiency virus pseudotypes with expanded cellular and species tropism. J. Virol. 64 (5), 2298-2308.
42. Spetz, A. L., Patterson, B. K., Lore, K., Andersson, J., and Holmgren, L. (1999). Functional gene transfer of HIV DNA by an HIV receptor-independent mechanism. J. Immunol. 163(2), 736-742.
43. Stanfield, R., Cabezas, E., Satterthwait, A., Stura, E., Profy, A., and Wilson, I. (1999). Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Struct. Fold Des. 7(2), 131-142.
44. Towbin, H., Staehelin, T., and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76(9), 4350-4354.
45. Trono, D., and Baltimore, D. (1990). A human cell factor is essential for HIV-1 Rev action. EMBO J. 9(12), 4155-4160.
46. Ulmer, J. B., Donnelly, J. J., Parker, S. E., Rhodes, G. H., Felgner, P. L., Dwarki, V. J., Gromkowski, S. H., Deck, R. R., DeWitt, C. M., Friedman, A., et al. (1993). Heterologous protection against influenza by injection of DNA encoding a viral protein [see comments]. Science 259(5102), 1745-1749.
47. UNAIDS/WHO. (2000). AIDS Epidemic Update: December 2000. UNAIDS/WHO, Paris.
48. Wahren, B. (1994). New observations on functional and neutralizing humoral immune response to HIV. AIDS 8(Suppl. 1), 147-153.
49. Vitiello, A., Marchesini, D., Furze, J., Sherman, L. A., and Chesnut, R. W. (1991). Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex. J. Exp. Med. 173(4), 1007-1015.