Transient depletion of dividing T lymphocytes in mice induces the emergence of regulatory T cells and dominant tolerance to islet allografts

American Journal of Transplantation

Volumn 8, Issue 5, 2008, Pages 942-953

  Giraud, S ^a,b,d   Barrou, B ^a,b,d   Sebillaud, S ^a,b,d   Debre P ^a,b,d   Klatzmann, D ^a,c,d   Thomas Vaslin, V ^a,c,d  

^a SORBONNE UNIVERSITÉ   (France)

^b Laboratoire d'Immunologie Cellulaire et Tissulaire CNRS URA 625   (France)

^c CNRS   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Diabetes; Rodent; T cells; Tolerance suppression; Transplantation

Indexed keywords

GANCICLOVIR; HYDROXYUREA; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GRAFT RECIPIENT; HOMEOSTASIS; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SUICIDE GENE; T CELL DEPLETION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; HYDROXYUREA; IMMUNE TOLERANCE; ISLETS OF LANGERHANS TRANSPLANTATION; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED STRAINS; MODELS, ANIMAL; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION, HOMOLOGOUS;

EID: 42149152757     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02195.x     Document Type: Article

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