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Volumn 2, Issue 6, 2000, Pages 596-601

T-cell suicide gene therapy for organ transplantation: Induction of long-lasting tolerance to allogeneic heart without generalized immunosuppression

Author keywords

Allotransplantation; Ganciclovir; Graft; HSV1 TK; Mice; Suicide gene; Therapy; Transgenic; Vascularized

Indexed keywords

HERPES; HUMAN HERPESVIRUS 1; MUS MUSCULUS;

EID: 0034571645     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0208     Document Type: Article
Times cited : (9)

References (28)
  • 1
    • 0026503434 scopus 로고
    • Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A
    • Fruman, D. A., Klee, C. B., Bierer, B. E., and Burakoff, S. J. (1992). Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc. Natl. Acad. Sci. USA 89: 3686-3690.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3686-3690
    • Fruman, D.A.1    Klee, C.B.2    Bierer, B.E.3    Burakoff, S.J.4
  • 2
    • 0031027777 scopus 로고    scopus 로고
    • Infections in solid-organ transplant recipients
    • Patel, R., and Paya, C. V. (1997). Infections in solid-organ transplant recipients. Clin. Microbiol. Rev. 10: 86-124.
    • (1997) Clin. Microbiol. Rev. , vol.10 , pp. 86-124
    • Patel, R.1    Paya, C.V.2
  • 3
    • 0028000108 scopus 로고
    • Impact of immunosuppressants on host tissues and tolerance
    • Calne, R. (1994). Impact of immunosuppressants on host tissues and tolerance. Transplant. Proc. 26: 3065-3070.
    • (1994) Transplant. Proc. , vol.26 , pp. 3065-3070
    • Calne, R.1
  • 4
    • 0030915659 scopus 로고    scopus 로고
    • Chronic allograft failure: The clinical problem
    • Nagano, H., and Tilney, N. L. (1997). Chronic allograft failure: The clinical problem. Am. J. Med. Sci. 313: 305-309.
    • (1997) Am. J. Med. Sci. , vol.313 , pp. 305-309
    • Nagano, H.1    Tilney, N.L.2
  • 5
    • 0029881881 scopus 로고    scopus 로고
    • Induction of tolerance to cardiac allografts
    • Wood, K. J. (1996). Induction of tolerance to cardiac allografts. Curr. Opin. Cardiol. 11: 208-213.
    • (1996) Curr. Opin. Cardiol. , vol.11 , pp. 208-213
    • Wood, K.J.1
  • 6
    • 0029868668 scopus 로고    scopus 로고
    • New concepts in tolerance
    • Wood, K. J. (1996). New concepts in tolerance. Clin. Transplant. 10: 93-99.
    • (1996) Clin. Transplant. , vol.10 , pp. 93-99
    • Wood, K.J.1
  • 7
    • 0028702018 scopus 로고
    • Drug sensitivity ("suicide") genes for selective cancer chemotherapy
    • Moolten, F. L. (1994). Drug sensitivity ("suicide") genes for selective cancer chemotherapy. Cancer Gene Ther. 1: 279-287.
    • (1994) Cancer Gene Ther. , vol.1 , pp. 279-287
    • Moolten, F.L.1
  • 8
    • 0018251481 scopus 로고
    • Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine
    • Fyfe, J. A., Keller, P. M., Furman, P. A., Miller, R. L., and Elion, G. B. (1978). Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine. J. Biol. Chem. 253: 8721-8727.
    • (1978) J. Biol. Chem. , vol.253 , pp. 8721-8727
    • Fyfe, J.A.1    Keller, P.M.2    Furman, P.A.3    Miller, R.L.4    Elion, G.B.5
  • 9
    • 0023183303 scopus 로고
    • Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information
    • St. Clair, M. H., Lambe, C. U., and Furman, P. A. (1987). Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information. Antimicrob. Agents Chemother. 31: 844-849.
    • (1987) Antimicrob. Agents Chemother. , vol.31 , pp. 844-849
    • St. Clair, M.H.1    Lambe, C.U.2    Furman, P.A.3
  • 10
    • 0032931846 scopus 로고    scopus 로고
    • Would suicide gene therapy solve the T-cell dilemma of allogeneic bone marrow transplantation?
    • Cohen, J. L., Boyer, O., and Klatzmann, D. (1999). Would suicide gene therapy solve the T-cell dilemma of allogeneic bone marrow transplantation? Immunol. Today 20: 172-176.
    • (1999) Immunol. Today , vol.20 , pp. 172-176
    • Cohen, J.L.1    Boyer, O.2    Klatzmann, D.3
  • 11
    • 0016803914 scopus 로고
    • Bone-marrow transplantation
    • Thomas, E., et al. (1975). Bone-marrow transplantation. N. Engl. J. Med. 292: 832-843.
    • (1975) N. Engl. J. Med. , vol.292 , pp. 832-843
    • Thomas, E.1
  • 12
    • 0029076989 scopus 로고
    • Allorecognition and graft-versus-host disease
    • Theobald, M. (1995). Allorecognition and graft-versus-host disease. Bone Marrow Transplant. 15: 489-498.
    • (1995) Bone Marrow Transplant. , vol.15 , pp. 489-498
    • Theobald, M.1
  • 13
    • 0030919862 scopus 로고    scopus 로고
    • Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes
    • Cohen, J. L., et al. (1997). Prevention of graft-versus-host disease in mice using a suicide gene expressed in T lymphocytes. Blood 89: 4636-4645.
    • (1997) Blood , vol.89 , pp. 4636-4645
    • Cohen, J.L.1
  • 14
    • 0031154829 scopus 로고    scopus 로고
    • Inhibition of graft-versus-host disease. Use of a T cell-controlled suicide gene
    • Helene, M., Lake-Bullock, V., Bryson, J. S., Jennings, C. D., and Kaplan, A. M. (1997). Inhibition of graft-versus-host disease. Use of a T cell-controlled suicide gene. J. Immunol. 158: 5079-5082.
    • (1997) J. Immunol. , vol.158 , pp. 5079-5082
    • Helene, M.1    Lake-Bullock, V.2    Bryson, J.S.3    Jennings, C.D.4    Kaplan, A.M.5
  • 15
    • 0028795530 scopus 로고
    • Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation
    • Bordignon, C., et al. (1995). Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation. Hum. Gene Ther. 6: 813-819.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 813-819
    • Bordignon, C.1
  • 16
    • 16944365744 scopus 로고    scopus 로고
    • Use of donor T-lymphocytes expressing herpes-simplex thymidine kinase in allogeneic bone marrow transplantation: A phase I-II study
    • Tiberghien, P., et al. (1997). Use of donor T-lymphocytes expressing herpes-simplex thymidine kinase in allogeneic bone marrow transplantation: A phase I-II study. Hum. Gene Ther. 8: 615-624.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 615-624
    • Tiberghien, P.1
  • 17
    • 0031975258 scopus 로고    scopus 로고
    • Adoptive immunotherapy for leukemia: Donor lymphocytes transduced with the herpes simplex thymidine kinase gene for remission induction
    • Link, C. J., et al. (1998). Adoptive immunotherapy for leukemia: Donor lymphocytes transduced with the herpes simplex thymidine kinase gene for remission induction. Hum. Gene Ther. 9: 115-134.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 115-134
    • Link, C.J.1
  • 18
    • 0034720613 scopus 로고    scopus 로고
    • Prolonged allograft survival through conditional and specific ablation of alloreactive T cells expressing a suicide gene
    • Thomas-Vaslin, V., et al. (2000). Prolonged allograft survival through conditional and specific ablation of alloreactive T cells expressing a suicide gene. Transplantation 69: 2154-2161.
    • (2000) Transplantation , vol.69 , pp. 2154-2161
    • Thomas-Vaslin, V.1
  • 19
    • 0033966814 scopus 로고    scopus 로고
    • Tolerance induced without immunosuppression in a T-lymphocyte suicide-gene therapy cardiac allograft model in mice
    • Braunberger, E., et al. (2000). Tolerance induced without immunosuppression in a T-lymphocyte suicide-gene therapy cardiac allograft model in mice. J. Thorac. Cardiovasc. Surg. 119: 46-51.
    • (2000) J. Thorac. Cardiovasc. Surg. , vol.119 , pp. 46-51
    • Braunberger, E.1
  • 20
    • 0030022783 scopus 로고    scopus 로고
    • Characterization of an intronless CD4 minigene expressed in mature CD4 and CD8 T cells, but not expressed in immature thymocytes
    • Salmon, P., Boyer, O., Lores, P., Jami, J., and Klatzmann, D. (1996). Characterization of an intronless CD4 minigene expressed in mature CD4 and CD8 T cells, but not expressed in immature thymocytes. J. Immunol. 156: 1873-1879.
    • (1996) J. Immunol. , vol.156 , pp. 1873-1879
    • Salmon, P.1    Boyer, O.2    Lores, P.3    Jami, J.4    Klatzmann, D.5
  • 21
    • 7844225923 scopus 로고    scopus 로고
    • Fertile homozygous transgenic mice expressing a functional truncated herpes simplex thymidine kinase ΔTK gene
    • Cohen, J. L., et al. (1998). Fertile homozygous transgenic mice expressing a functional truncated herpes simplex thymidine kinase ΔTK gene. Transgenic Res. 7: 321-330.
    • (1998) Transgenic Res. , vol.7 , pp. 321-330
    • Cohen, J.L.1
  • 22
    • 0015866545 scopus 로고
    • Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection
    • Corry, R. J., Winn, H. J., and Russell, P. S. (1973). Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection. Transplantation 16: 343-350.
    • (1973) Transplantation , vol.16 , pp. 343-350
    • Corry, R.J.1    Winn, H.J.2    Russell, P.S.3
  • 23
    • 0033592304 scopus 로고    scopus 로고
    • FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation
    • Hwang, M. W., et al. (1999). FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation. Circulation 100: 1322-1329.
    • (1999) Circulation , vol.100 , pp. 1322-1329
    • Hwang, M.W.1
  • 24
    • 0028318927 scopus 로고
    • Split tolerance induced by orthotopic liver transplantation in mice
    • Dahmen, U., et al. (1994). Split tolerance induced by orthotopic liver transplantation in mice. Transplantation 58: 1-8.
    • (1994) Transplantation , vol.58 , pp. 1-8
    • Dahmen, U.1
  • 25
    • 0030659068 scopus 로고    scopus 로고
    • Species differences in the expression of major histocompatibility complex class II antigens on coronary artery endothelium: Implications for cell-mediated xenoreactivity
    • Choo, J. K., et al. (1997). Species differences in the expression of major histocompatibility complex class II antigens on coronary artery endothelium: Implications for cell-mediated xenoreactivity. Transplantation 64: 1315-1322.
    • (1997) Transplantation , vol.64 , pp. 1315-1322
    • Choo, J.K.1
  • 26
    • 0032872566 scopus 로고    scopus 로고
    • Tolerance to vascularized organ allografts in large-animal models
    • Kawai, T., Sachs, D. H., and Cosimi, A. B. (1999). Tolerance to vascularized organ allografts in large-animal models. Curr. Opin. Immunol. 11: 516-520.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 516-520
    • Kawai, T.1    Sachs, D.H.2    Cosimi, A.B.3
  • 27
    • 0030843493 scopus 로고    scopus 로고
    • HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia
    • Bonini, C., et al. (1997). HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia. Science 276: 1719-1724.
    • (1997) Science , vol.276 , pp. 1719-1724
    • Bonini, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.