Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 4, 2008, Pages 1419-1429

  Huang, Peiyong ^a   Goff, Dane A ^a   Huang, Qi ^a   Martinez, Anthony ^a   Xu, Xiang ^a   Crowder, Scott ^a   Issakani, Sarkiz D ^a   Anderson, Emily ^a   Sheng, Ning ^a   Achacoso, Philip ^a   Yen, Ann ^a   Kinsella, Todd ^a   Darwish, Ihab S ^a   Kolluri, Rao ^a   Hong, Hui ^a   Qu, Kunbin ^a   Stauffer, Emily ^a   Goldstein, Eileen ^a   Singh, Rajinder ^a   Payan, Donald G ^a   Lu, H Henry ^a   more..

^a RIGEL PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; FURAPROFEN; HETEROCYCLIC COMPOUND; R 706; RIBAVIRIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BIOCHEMICAL COMPOSITION; CELL ASSAY; CHEMICAL STRUCTURE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPLICON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS REPLICATION; WESTERN BLOTTING;

ANTIVIRAL AGENTS; BENZOFURANS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG INTERACTIONS; DRUG RESISTANCE, VIRAL; GENOTYPE; HEPACIVIRUS; HETEROCYCLIC COMPOUNDS; HUMANS; INTERFERON-ALPHA; MICROBIAL SENSITIVITY TESTS; REPLICON; RNA, VIRAL; VIRUS REPLICATION;

EID: 42049092061     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00525-07     Document Type: Article

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