Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations

Journal of the American Chemical Society

Volumn 130, Issue 10, 2008, Pages 3157-3168

  Yuan, Yue ^a   Bleile, Dustin W ^a   Wen, Xin ^b   Sanders, David A R ^c   Itoh, Kenji ^d   Liu, Hung Wen ^d   Pinto, B Mario ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b NANKAI UNIVERSITY   (China)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KLEBSIELLA PNEUMONIAE; UDP-GALACTOPYRANOSE MUTASE (UGM);

BIOSYNTHESIS; COMPUTER SIMULATION; LIGANDS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ENZYME ACTIVITY;

ISOENZYME; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOPYRANOSE MUTASE; URIDINE DIPHOSPHATE GALACTOSE;

AB INITIO CALCULATION; ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SUBSTRATE; KLEBSIELLA PNEUMONIAE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SIMULATION;

COMPUTER SIMULATION; GALACTOSE; INTRAMOLECULAR TRANSFERASES; KLEBSIELLA PNEUMONIAE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MOLECULAR CONFORMATION; PROTEIN BINDING; REFERENCE STANDARDS; URIDINE DIPHOSPHATE;

EID: 41449091694     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja7104152     Document Type: Article

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