Galactan biosynthesis in Mycobacterium tuberculosis: Identification of a bifunctional UDP-galactofuranosyltransferase

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26430-26440

  Kremer, Laurent ^a,e   Dover, Lynn G ^a   Morehouse, Caroline ^a   Hitchin, Paul ^b,c   Everett, Martin ^c   Morris, Howard R ^b   Dell, Ann ^b   Brennan, Patrick J ^d   McNeil, Michael R ^d   Flaherty, Christopher ^a   Duncan, Ken ^c   Besra, Gurdyal S ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d Department of Environmental and Radiological Health Sciences   (United States)

^e INSTITUT PASTEUR DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOASSAY; BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CATALYSIS; CELLS; ENZYME KINETICS; ESCHERICHIA COLI; POLYMERIZATION;

MYCOBACTERIAL INFECTIONS; TUBERCULOSIS;

BIOCHEMISTRY;

GALACTAN; GALACTOSYLTRANSFERASE; MYCOLIC ACID; PEPTIDOGLYCAN; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; URIDINE DIPHOSPHATE GALACTOFURANOSYLTRANSFERASE; BACTERIAL PROTEIN;

ARTICLE; AUTORADIOGRAPHY; BACTERIAL CELL WALL; BIOSYNTHESIS; CATALYSIS; ESCHERICHIA COLI; GAS CHROMATOGRAPHY; GENE OVEREXPRESSION; HYDROPHOBICITY; MASS SPECTROMETRY; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; ENZYME SPECIFICITY; METABOLISM;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

BACTERIAL PROTEINS; GALACTANS; GALACTOSYLTRANSFERASES; MYCOBACTERIUM TUBERCULOSIS; SUBSTRATE SPECIFICITY;

EID: 0035854786     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102022200     Document Type: Article

References (60)

1. Bloom, B. R., and Murray, C. J. (1992) Science 257, 1055-1064
2. Barry, C. E., III. Biochem. Pharmacol. (1997) 54, 1165-1172
3. Young, D. B., and Dunkan, K. (1995) Annu. Rev. Microbiol. 49, 641-673
4. Daffé, M., Brennan, P. J., and McNeil, M. (1990) J. Biol. Chem. 265, 6734-6743
5. McNeil, M., Daffé, M., and Brennan, P. J. (1990) J. Biol. Chem. 265, 18200-18206
6. McNeil, M. R. (1999) in Genetics of Bacterial Polysaccharides (J. Goldberg, ed) pp. 207-223, CRC Press, Boca Raton, FL
7. Besra, G. S., Khoo, K.-H., McNeil, M. R., Dell, A., Morris, H. R., and Brennan, P. J. (1995) Biochemistry 34, 4257-4266
8. Quémard, A., Lacave, C., and Lanéelle, G. (1991) Antimicrob. Agents Chemother. 35, 1035-1039
9. Banerjee, A., Dubnau, E., Quemard, A., Balasubramanian, V., Um, K. S., Wilson, T., Collins, D., de Lisle, G., and Jacobs, W. R., Jr. (1994) Science 263, 227-230
10. Kremer, L., Baulard, A. R., and Besra, G. S. (2000) in Molecular Genetics of Mycobacteria (Hatfull, G. F., and Jacobs, W. R., Jr., eds) pp. 173-190, ASM Press, Washington D. C.
11. Mdluli, K., Slayden, R. A., Zhu, Y. Q., Ramaswamy, S., Pan, X., Mead, D., Crane, D. D., Musser, J. M., and Barry, C. E., III. (1998) Science 280, 1607-1610
12. Kremer, L., Douglas, J. D., Baulard, A. R., Morehouse, C., Guy, M. R., Alland, D., Dover, L. G., Lakey, J. H., Jacobs, W. R., Jr., Brennan, P. J., Minnikin, D. E., and Besra, G. S. (2000) J. Biol. Chem. 275, 16857-16864
13. Slayden, R. A., Lee, R. E., and Barry, C. E. (2000) Mol. Microbiol. 38, 514-525
14. Takayama, K., Armstrong, E. L., Kunigi, K. A., and Kilburn, J. O. (1979) Antimicrob. Agents Chemother. 16, 240-242
15. Kilburn, J. O., and Takayama, K. (1981) Antimicrob. Agents Chemother. 20, 401-404
16. Takayama, K., and Kilburn, J. O. (1989). Antimicrob. Agents Chemother. 33, 1493-1499
17. Mikusova, K., Slayden, R. A., Besra, G. S., and Brennan P. J. (1995) Antimicrob. Agents Chemother. 39, 2484-2489
18. Belanger, A. E., Besra, G. S., Ford, M. E., Mikusova, K., Belisle, J. T., Brennan, P. J., and Inamine, J. M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11919-11924
19. Mikusova, K., Mikus, M., Besra, G. S., Hancock, I., and Brennan, P. J. (1996) J. Biol. Chem. 271, 7820-7828
20. Mikusova, K., Yagi, T., Stern, R., McNeil, M. R., Besra, G. S., Crick, D. C., and Brennan, P. J. (2000) J. Biol. Chem. 275, 33890-33897
21. Ma, Y., Mills, J. A., Belisle, J. T., Vissa, V., Howell, M., Bowlin, K., Scherman, M. S., and McNeil, M. (1997) Microbiology 143, 937-945
22. Hoang, T. T., Ma, Y., Stern, R. J., McNeil, M. R., and Schweizer, H. P. (1999) Gene 237, 361-371
23. Weston, A., Stern, R. J., Lee, R. E., Nassau, P. M., Monsey, D., Martin, S. L., Scherman, M. S., Besra, G. S., Duncan, K., and McNeil, M. R. (1998) Tuber. Lung Dis. 78, 123-131
24. Stern, R. J., Lee, T. Y., Lee, T. J., Yan, W., Scherman, M. S., Vissa, V. D., Kim, S. K., Wanner, B. L., and McNeil, M. R. (1999) Microbiology 145, 663-671
25. Ward, J. B. (1977) FEBS Lett. 78, 151-154
26. Ward, J. B., and Curtis, C. A. (1982) Eur. J. Biochem. 122, 125-132
27. Snapper, S. B., Melton, R. E., Mustafa, S., Kieser, T., and Jacobs, W. R., Jr. (1990) Mol. Microbiol. 4, 1911-1919
28. Kremer, L., Baulard, A., Estaquier, J., Content, J., Capron, A., and Locht, C. (1995) J. Bacteriol. 177, 642-653
29. Stover, C. K., de la Cruz, V. F., Fuerst, T. R., Burlein, J. E., Benson, L. A., Bansal, G. P., Young, J. F., Lee, M. H., Hatfull, G. F., Snapper, S. B., Barletta, R. G., Jacobs, W. R., Jr., and Bloom, B. R. (1991) Nature 351, 456-460
30. Baulard, A., Jourdan, C., Mercenier, A., and Locht, C. (1992) Nucleic Acids Res. 20, 4105
31. Sambrook, J., Fritsch, F. E., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
32. Sugawara, F., Nakayama, H., and Ogawa, T. (1986) Agric. Biol. Chem. 50, 1557-1561
33. Veeneman, G. H., Notermans, S., Hoogerhout, P., and van Boom, J. H. (1989) Recl. Trav. Chim. Pays-Bas 108, 344-350
34. Wolfrom, M. L., McWain, P., Pagnucco, R., and Thompson, A. (1964) J. Org. Chem. 29, 454-457
35. Zurmond, H. M., vander Klein, P. A. M., Veeneman, G. H., and van Boom, J. H. (1990) Recl. Trav. Chim. Pays-Bas. 109, 437-441
36. Besra, G. S., Sievert, T., Lee, R. E., Slayden, R. A., Brennan, P. J., and Takayama, K. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12735-12739
37. Dell, A., Reason, A. J., Khoo, K. H., Panico, M., McDowell, R. A., and Morris, H. R. (1994) Methods Enzymol. 230, 108-132
38. Paulson, J. C., and Colley, K. J. (1989) J. Biol. Chem. 264, 17615-17618
39. Joziasse, D. H. (1992) Glycobiology 2, 271-277
40. Gaboriaud, C., Bissery, V., Benchetrit, T., and Mornon, J. P. (1987) FEBS Lett. 224, 149-155
41. Wiggins, C. A., and Munro, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7945-7950
42. Shibayama, K., Ohsuka, S., Tanaka, T., Arakawa, Y., and Ohta, M. (1998) J. Bacteriol. 180, 5313-5318
43. Breton, C., Bettler, E., Joziasse, D. H., Geremia, R. A., and Imberty, A. (1998) J. Biochem. (Tokyo) 123, 1000-1009
44. Hagen, F. K., Hazes, B., Raffo, R., deSa, D., and Tabak, L. A. (1999) J. Biol. Chem. 274, 6797-6803
45. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410
46. Lee, R. E., Brennan, P. J., and Besra, G. S. (1997) Glycobiology 7, 1121-1128
47. Barlow, J. N., and Blanchard, J. S. (2000) Carbohydr. Res. 328, 473-480
48. Whitfield, C. (1995) Trends Microbiol. 3, 178-185
49. Hagopian, A., and Eylar, E. H. (1968) Arch. Biochim. Biophys. 128, 422-433
50. Petit, C., Rigg, G. P., Pazzani, C., Smith, A., Sieberth, V., Stevens, M., Boulnois, G., Jann, K., and Roberts, I. S. (1995) Mol. Microbiol. 17, 611-620
51. Griffiths, G., Cook, N. J., Gottfridson, E., Lind, T., Lidholt, K., and Roberts, I. S. (1998) J. Biol. Chem. 273, 11752-11757
52. Weigel, P. H., Hascall, V. C., and Tammi, M. (1997) J. Biol. Chem. 272, 13997-14000
53. DeAngelis, P. L. (1999) J. Biol. Chem. 274, 26557-26562
54. Jing, W., and DeAngelis, P. L. (2000) Glycobiology 10, 883-889
55. Cartee R. T., Forsee, W. T., Schutzbach, J. S., and Yother, J. (2000) J. Biol. Chem. 275, 3907-3914
56. Clarke, B. R., Bronner, D., Kleenleyside, W. J., Severn, W. B., Richards, J. C., and Whitfield, C. (1995) J. Bacteriol. 177, 5411-5418
57. Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., III, Tekaia, F., Badcock, K., Basham, D., Brown, D., Chillingworth, T., Connor, R., Davies, R., Devlin, K., Feltwell, T., Gentles, S., Hamlin, N., Holroyd, S., Hornsby, T., Jagels, K., Krogh, A., McLean, J., Moule, S., Murphy, L., Oliver, K., Osborne, J., Quail, M. A., Rajandream, M. A., Rogers, J., Rutter, S., Seeger, K., Skelton, J., Squares, S., Squares, R., Sulston, J. E., Taylor, K., Whitehead, S., and Barrell, B. G. (1998) Nature 393, 537-544
58. Telenti, A., Philipp, W. J., Sreevatsan, S., Bernasconi, C., Stockbauer, K. E., Wieles, B., Musser, J. M., and Jacobs, W. R., Jr. (1997) Nat. Med. 3, 567-570
59. Belisle, J. T., Vissa, V. D., Sievert, T., Takayama, K., Brennan, P. J., and Besra, G. S. (1997) Science 276, 1420-1422
60. Saxena, I. M., Brown R. M., Jr., Fevre, M., Geremia, R. A., and Henrissat, B. (1995) J. Bacteriol. 177, 1419-1424