Functionality maps of the ATP binding site of DNA gyrase B: Generation of a consensus model of ligand binding

Journal of Medicinal Chemistry

Volumn 47, Issue 18, 2004, Pages 4373-4390

  Schechner, Martina ^a   Sirockin, Finton ^a,c   Stote, Roland H ^b   Dejaegere, Annick P ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ LOUIS PASTEUR   (France)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; COUMARIN; DNA TOPOISOMERASE (ATP HYDROLYSING) B; LIGAND; SOLVENT;

ARTICLE; BINDING SITE; CHEMICAL MODEL; CLUSTER ANALYSIS; CONFORMATIONAL TRANSITION; DIELECTRIC CONSTANT; DIELECTRIC MODEL; ENZYME ACTIVE SITE; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROCESSING;

ADENOSINE TRIPHOSPHATE; BINDING SITES; COMPUTER SIMULATION; COUMARINS; DNA GYRASE; ESCHERICHIA COLI PROTEINS; LIGANDS; MODELS, MOLECULAR; PLIABILITY; PROTEIN BINDING; PYRROLES; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4143144121     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0311184     Document Type: Article

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