Probing the binding of coumarins and cyclothialidines to DNA gyrase

Biochemistry

Volumn 38, Issue 7, 1999, Pages 1967-1976

  Kampranis, Sotirios C ^c   Gormley, Niall A ^a,c   Tranter, Rebecca ^a,c   Orphanides, George ^b,c   Maxwell, Anthony ^c  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ASPARAGINE; ASPARTIC ACID; CLOROBIOCIN; COUMARIN DERIVATIVE; CYCLOTHIALIDINE DERVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); GR 122222X; GYRASE INHIBITOR; LEUCINE; NOVOBIOCIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG DNA BINDING; DRUG TARGETING; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATE; ARGININE; ASPARAGINE; ASPARTIC ACID; BINDING SITES; COUMARINS; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; HYDROLYSIS; KINETICS; MUTAGENESIS, SITE-DIRECTED; PEPTIDES, CYCLIC; SURFACE PLASMON RESONANCE; TRYPSIN;

EID: 0033573856     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982320p     Document Type: Article

References (38)

1. Maxwell, A. (1997) Trends Microbiol. 5, 102-109.
2. Drlica, K., and Zhao, X. (1997) Microbiol. Mol. Biol. Rev. 61, 377-392.
3. Maxwell, A., and Critchlow, S. E. (1997) Mode of action, in Handbook of Experimental Pharmacology - Quinolone Anti-bacterials (Kuhlmann, J., Dalhoff, A., and Zeiler, H.-J., Eds.) Vol. 127, pp 119-166, Springer-Verlag, Berlin, Germany.
4. Reece, R. J., and Maxwell, A. (1991) CRC Crit. Rev. Biochem. Mol. Biol. 26, 335-375.
5. Wigley, D. B. (1995) Annu. Rev. Biophys. Biomol. Struct. 24, 185-208.
6. Morais Cabral, J. H., Jackson, A. P., Smith, C. V., Shikotra, N., Maxwell, A., and Liddington, R. C. (1997) Nature 388, 903-906.
7. Wigley, D. B., Davies, G. J., Dodson, E. J., Maxwell, A., and Dodson, G. (1991) Nature 351, 624-629.
8. Mizuuchi, K., O'Dea, M. H., and Gellert, M. (1978) Proc. Natl. Acad. Sci. U.S.A. 75, 5960-5963.
9. Sugino, A., Higgins, N. P., Brown, P. O., Peebles, C. L., and Cozzarelli, N. R. (1978) Proc. Natl. Acad. Sci. U.S.A. 75, 4838-4842.
10. del Castillo, I., Vizan, J., Rodriguez-Sainz, M., and Moreno, F. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 8860-8864.
11. Contreras, A., and Maxwell, A. (1992) Mol. Microbiol. 6, 1617-1624.
12. Gilbert, E. J., and Maxwell, A. (1994) Mol. Microbiol. 12, 365-373.
13. Nakada, N., Gmünder, H., Hirata, T., and Arisawa, M. (1994) Antimicrob. Agents Chemother. 38, 1966-1973.
14. Stieger, M., Angehrn, P., Wohlgensinger, B., and Gmünder, H. (1996) Antimicrob. Agents Chemother. 40, 1060-1062.
15. Nakada, N., Gmünder, H., Hirata, T., and Arisawa, M. (1995) J. Biol. Chem. 270, 14286-14291.
16. Oram, M., Dosanjh, B., Gormley, N. A., Smith, C. V., Fisher, L. M., Maxwell, A., and Duncan, K. (1996) Antimicrob. Agents Chemother. 40, 473-476.
17. Lewis, R. J., Singh, O. M. P., Smith, C. V., Skarynski, T., Maxwell, A., Wonacott, A. J., and Wigley, D. B. (1996) EMBO J. 15, 1412-1420.
18. Tsai, F. T. F., Singh, O. M. P., Skarzynski, T., Wonacott, A. J., Weston, S., Tucker, A., Pauptit, R. A., Breeze, A. L., Poyser, J. P., O'Brien, R., Ladbury, J. E., and Wigley, D. B. (1997) Proteins: Struct., Funct., Genet. 28, 41-52.
19. Holdgate, G. A., Tunnicliffe, A., Ward, W. H. J., Weston, S. A., Rosenbrock, G., Barth, P. T., Taylor, I. W. F., Pauptit, R. A., and Timms, D. (1997) Biochemistry 36, 9663-9673.
20. Maxwell, A. (1993) Mol. Microbiol. 9, 681-686.
21. Orr, E., Fairweather, N. F., Holland, I. B., and Pritchard, R. H. (1979) Mol. Gen. Genet. 177, 103-112.
22. Holmes, M. L., and Dyall-Smith, M. L. (1991) J. Bacteriol. 173, 642-648.
23. Sugino, A., and Cozzarelli, N. R. (1980) J. Biol. Chem. 255, 6299-6306.
24. Staudenbauer, W. L., and Orr. E. (1981) Nucleic Acids Res. 9, 3589-3603.
25. Ali, J. A., Orphanides, G., and Maxwell, A. (1995) Biochemistry 34, 9801-9808.
26. Kampranis, S. C., and Maxwell, A. (1998) J. Biol. Chem. 273, 22606-22614.
27. Ali, J. A., Jackson, A. P., Howells, A. J., and Maxwell, A. (1993) Biochemistry 32, 2717-2724.
28. Maxwell, A., and Howells, A. J. (1998) Overexpression and purification of bacterial DNA gyrase, in Protocols for DNA topoisomerases I. DNA topology and enzyme purification (Bjornsti, M.-A., and Osheroff, N., Eds.) pp 135-144, Humana Press, Towata, New Jersey.
29. Gormley, N. A., Orphanides, G., Meyer, A., Cullis, P. M., and Maxwell, A. (1996) Biochemistry 35, 5083-5092.
30. Samuels, D. S., Marconi, R. T., Huang, W. M., and Garon, C. F. (1994) J. Bacteriol. 176, 3072-3075.
31. Reece, R. J., and Maxwell, A. (1989) J. Biol. Chem. 264, 19648-19653.
32. Jackson, A. P., and Maxwell, A. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 11232-11236.
33. Kampranis, S. C., and Maxwell. A. (1998) J. Biol. Chem. 273, 26305-26309.
34. Lindsley, J. E., and Wang, J. C. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 10485-10489.
35. Lindsley, J. E., and Wang, J. C. (1993) Nature 361, 749-750.
36. Harkins, T. T., and Lindsley, J. E. (1998) Biochemistry 37, 7292-7298.
37. Harkins, T. T., Lewis, T. J., and Lindsley, J. E. (1998) Biochemistry 37, 7299-7312.
38. Szabo, A., Stolz, L., and Granzow. R. (1995) Curr. Opin. Struct. Biol. 5, 699-705.