An antagonist of retinoic acid receptors more effectively inhibits growth of human prostate cancer cells than normal prostate epithelium

British Journal of Cancer

Volumn 91, Issue 3, 2004, Pages 580-588

  Keedwell, R G ^a   Zhao, Y ^b   Hammond, L A ^a   Wen, K ^a   Qin, S ^b   Atangan, L I ^b   Shurland, D L ^b   Wallace, D M A ^c   Bird, R ^a   Reitmair, A ^b   Chandraratna, R A S ^b   Brown, G ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^b ALLERGAN INC   (United States)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; Growth inhibition; Prostate cancer; RAR antagonists; Retinoic acid receptors

Indexed keywords

AGN 194310; AGN 194431; AGN 196996; ANTINEOPLASTIC AGENT; CASPASE; DNA FRAGMENT; LIPOCORTIN 5; PROTEIN P21; RECEPTOR BLOCKING AGENT; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROSTATE EPITHELIUM; PROTEIN BINDING;

APOPTOSIS; BENZOIC ACIDS; CARCINOMA; CASPASES; DNA DAMAGE; EPITHELIAL CELLS; HUMANS; MALE; PROSTATE; PROSTATIC NEOPLASMS; RECEPTORS, RETINOIC ACID; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 4143143324     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602024     Document Type: Article

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