A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities

Leukemia

Volumn 14, Issue 2, 2000, Pages 255-261

  Duprez, E ^a   Benoit, G ^a   Flexor, M ^a   Lillehaug, J R ^b   Lanotte, M ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Acute promyelocytic leukemia (APL); Maturation; Mutated receptor; NB4 R2; PML RARA; Retinoid resistance

Indexed keywords

CHIMERIC PROTEIN; GLUTAMINE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID;

ACUTE MYELOBLASTIC LEUKEMIA; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CLONE; CONTROLLED STUDY; DRUG RESISTANCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BLOCKING; STOP CODON; TRANSACTIVATION;

EID: 0033962657     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401683     Document Type: Article

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