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Volumn 289, Issue 2, 2003, Pages 384-395

Caspase activity is not sufficient to execute cell death

Author keywords

Apoptosis; Caspases; Cdk2; Colony formation; Cytofluorimetry; Death commitment; Physiological cell death; Protein kinases

Indexed keywords

CASPASE; CASPASE DEPENDENT NUCLEAR CYCLIN DEPENDENT KINASE 2; UNCLASSIFIED DRUG;

EID: 0141565212     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00289-1     Document Type: Article
Times cited : (11)

References (63)
  • 1
    • 0018843454 scopus 로고
    • Mechanisms of immune lysis I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement
    • Russell J.H., Masakowski V.R., Dobos C.B. Mechanisms of immune lysis I. Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement. J. Immunol. 124:1980;1100-1105.
    • (1980) J. Immunol. , vol.124 , pp. 1100-1105
    • Russell, J.H.1    Masakowski, V.R.2    Dobos, C.B.3
  • 2
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie A.H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature. 284:1980;555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 3
    • 0026645504 scopus 로고
    • Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes
    • Ucker D.S., Obermiller P.S., Eckhart W., Apgar J.R., Berger N.A., Meyers J. Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes. Mol. Cell. Biol. 12:1992;3060-3069.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3060-3069
    • Ucker, D.S.1    Obermiller, P.S.2    Eckhart, W.3    Apgar, J.R.4    Berger, N.A.5    Meyers, J.6
  • 4
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis A basic biological phenomenon with wide-ranging implications in tissue kinetics . Br. J. Cancer. 26:1972;239-256.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-256
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 5
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., Henson P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:1992;2207-2216.
    • (1992) J. Immunol. , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 6
    • 0030785790 scopus 로고    scopus 로고
    • The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
    • Susin S.A., Zamzami N., Castedo M., Daugas E., Wang H.-G., Geley S., Fassy F., Reed J.C., Kroemer G. The central executioner of apoptosis multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis . J. Exp. Med. 186:1997;25-37.
    • (1997) J. Exp. Med. , vol.186 , pp. 25-37
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3    Daugas, E.4    Wang, H.-G.5    Geley, S.6    Fassy, F.7    Reed, J.C.8    Kroemer, G.9
  • 8
    • 0025754446 scopus 로고
    • Death by suicide: One way to go in mammalian cellular development?
    • Ucker D.S. Death by suicide one way to go in mammalian cellular development? New Biol. 3:1991;103-109.
    • (1991) New Biol. , vol.3 , pp. 103-109
    • Ucker, D.S.1
  • 9
    • 0029779280 scopus 로고    scopus 로고
    • Cdc25 cell-cycle phosphatase as a target of c-myc
    • Galaktionov K., Chen X., Beach D. Cdc25 cell-cycle phosphatase as a target of c-myc. Nature. 382:1996;511-517.
    • (1996) Nature , vol.382 , pp. 511-517
    • Galaktionov, K.1    Chen, X.2    Beach, D.3
  • 11
    • 0026557171 scopus 로고
    • Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice
    • Al-Ubaidi M.R., Hollyfield J.G., Overbeek P.A., Baehr W. Photoreceptor degeneration induced by the expression of simian virus 40 large tumor antigen in the retina of transgenic mice. Proc. Natl. Acad. Sci. USA. 89:1992;1194-1198.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1194-1198
    • Al-Ubaidi, M.R.1    Hollyfield, J.G.2    Overbeek, P.A.3    Baehr, W.4
  • 12
    • 0026492630 scopus 로고
    • Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice
    • Feddersen R.M., Ehlenfeldt R., Yunis W.S., Clark H.B., Orr H.T. Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice. Neuron. 9:1992;955-966.
    • (1992) Neuron , vol.9 , pp. 955-966
    • Feddersen, R.M.1    Ehlenfeldt, R.2    Yunis, W.S.3    Clark, H.B.4    Orr, H.T.5
  • 13
    • 0030585701 scopus 로고    scopus 로고
    • Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis
    • Radvanyi L.G., Shi Y., Mills G.B., Miller R.G. Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis. Cell. Immunol. 170:1996;260-273.
    • (1996) Cell. Immunol. , vol.170 , pp. 260-273
    • Radvanyi, L.G.1    Shi, Y.2    Mills, G.B.3    Miller, R.G.4
  • 15
    • 0033559980 scopus 로고    scopus 로고
    • The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis
    • Hakem A., Sasaki T., Kozieradzki I., Penninger J.M. The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis. J. Exp. Med. 189:1999;957-967.
    • (1999) J. Exp. Med. , vol.189 , pp. 957-967
    • Hakem, A.1    Sasaki, T.2    Kozieradzki, I.3    Penninger, J.M.4
  • 16
    • 0034949255 scopus 로고    scopus 로고
    • The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1 (ASK1)
    • Zou X., Tsutsui T., Ray D., Blomquist J.F., Ichijo H., Ucker D.S., Kiyokawa H. The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1 (ASK1). Mol. Cell. Biol. 21:2001;4818-4828.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4818-4828
    • Zou, X.1    Tsutsui, T.2    Ray, D.3    Blomquist, J.F.4    Ichijo, H.5    Ucker, D.S.6    Kiyokawa, H.7
  • 17
    • 0037034870 scopus 로고    scopus 로고
    • The subcellular localization of cyclin dependent kinase 2 determines the fate of mesangial cells: Role in apoptosis and proliferation
    • Hiromura K., Pippin J.W., Blonski M.J., Roberts J.M., Shankland S.J. The subcellular localization of cyclin dependent kinase 2 determines the fate of mesangial cells role in apoptosis and proliferation . Oncogene. 21:2002;1750-1758.
    • (2002) Oncogene , vol.21 , pp. 1750-1758
    • Hiromura, K.1    Pippin, J.W.2    Blonski, M.J.3    Roberts, J.M.4    Shankland, S.J.5
  • 18
    • 0027999537 scopus 로고
    • Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death
    • Casciola-Rosen L.A., Miller D.K., Anhalt G.J., Rosen A. Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death. J. Biol. Chem. 269:1994;30757-30760.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30757-30760
    • Casciola-Rosen, L.A.1    Miller, D.K.2    Anhalt, G.J.3    Rosen, A.4
  • 19
    • 0028102478 scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature. 371:1994;346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 21
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
    • Casciola-Rosen L., Nicholson D.W., Chong T., Rowan K.R., Thomberry N.A., Miller D.K., Rosen A. Apopain/CPP32 cleaves proteins that are essential for cellular repair a fundamental principle of apoptotic death . J. Exp. Med. 183:1996;1957-1964.
    • (1996) J. Exp. Med. , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.1    Nicholson, D.W.2    Chong, T.3    Rowan, K.R.4    Thomberry, N.A.5    Miller, D.K.6    Rosen, A.7
  • 23
    • 0030465544 scopus 로고    scopus 로고
    • Lamin proteolysis facilitates nuclear events during apoptosis
    • Rao L., Perez D., White E. Lamin proteolysis facilitates nuclear events during apoptosis. J. Cell Biol. 135:1996;1441-1455.
    • (1996) J. Cell Biol. , vol.135 , pp. 1441-1455
    • Rao, L.1    Perez, D.2    White, E.3
  • 24
    • 0030890790 scopus 로고    scopus 로고
    • Processing/activation of at least four interleukin-1β converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells
    • MacFarlane M., Cain K., Sun X.-M., Alnemri E.S., Cohen G.M. Processing/activation of at least four interleukin-1β converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells. J. Cell Biol. 137:1997;469-479.
    • (1997) J. Cell Biol. , vol.137 , pp. 469-479
    • MacFarlane, M.1    Cain, K.2    Sun, X.-M.3    Alnemri, E.S.4    Cohen, G.M.5
  • 25
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari M., Sakahira H., Yokoyama H., Okawa K., Iwamatsu A., Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 391:1998;43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 26
    • 0035831473 scopus 로고    scopus 로고
    • Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis
    • Slee E.A., Adrain C., Martin S.J. Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis. J. Biol. Chem. 276:2001;7320-7326.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7320-7326
    • Slee, E.A.1    Adrain, C.2    Martin, S.J.3
  • 27
    • 0031921562 scopus 로고    scopus 로고
    • Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2, caspase, and cyclin-dependent kinase activities
    • Harvey K.J., Blomquist J.F., Ucker D.S. Commitment and effector phases of the physiological cell death pathway elucidated with respect to Bcl-2, caspase, and cyclin-dependent kinase activities. Mol. Cell. Biol. 18:1998;2912-2922.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2912-2922
    • Harvey, K.J.1    Blomquist, J.F.2    Ucker, D.S.3
  • 29
    • 0032499702 scopus 로고    scopus 로고
    • Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells
    • Zhou B.-B., Li H., Yuan J., Kirschner M.W. Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells. Proc. Natl. Acad. Sci. USA. 95:1998;6785-6790.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6785-6790
    • Zhou, B.-B.1    Li, H.2    Yuan, J.3    Kirschner, M.W.4
  • 30
    • 0037063622 scopus 로고    scopus 로고
    • A role for G1/S cyclin-dependent protein kinases in the apoptotic response to ionizing radiation
    • Finkielstein C.V., Chen L.G., Maller J.L. A role for G1/S cyclin-dependent protein kinases in the apoptotic response to ionizing radiation. J. Biol. Chem. 277:2002;38476-38485.
    • (2002) J. Biol. Chem. , vol.277 , pp. 38476-38485
    • Finkielstein, C.V.1    Chen, L.G.2    Maller, J.L.3
  • 31
    • 0034627832 scopus 로고    scopus 로고
    • Caspase-dependent Cdk activity is a requisite effector of apoptotic death events
    • Harvey K.J., Lukovic D., Ucker D.S. Caspase-dependent Cdk activity is a requisite effector of apoptotic death events. J. Cell Biol. 148:2000;59-72.
    • (2000) J. Cell Biol. , vol.148 , pp. 59-72
    • Harvey, K.J.1    Lukovic, D.2    Ucker, D.S.3
  • 32
    • 0042829001 scopus 로고    scopus 로고
    • Membrane-targeted green fluorescent protein reliably and uniquely marks cells through apoptotic death
    • Harvey K.J., Lukovic D., Ucker D.S. Membrane-targeted green fluorescent protein reliably and uniquely marks cells through apoptotic death. Cytometry. 43:2001;273-278.
    • (2001) Cytometry , vol.43 , pp. 273-278
    • Harvey, K.J.1    Lukovic, D.2    Ucker, D.S.3
  • 33
    • 0034608386 scopus 로고    scopus 로고
    • Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates
    • Komoriya A., Packard B.Z., Brown M.J., Wu M.L., Henkart P.A. Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates. J. Exp. Med. 191:2000;1819-1828.
    • (2000) J. Exp. Med. , vol.191 , pp. 1819-1828
    • Komoriya, A.1    Packard, B.Z.2    Brown, M.J.3    Wu, M.L.4    Henkart, P.A.5
  • 34
    • 0029910914 scopus 로고    scopus 로고
    • Profluorescent protease substrates: Intramolecular dimers described by the exciton model
    • Packard B.Z., Toptygin D.D., Komoriya A., Brand L. Profluorescent protease substrates Intramolecular dimers described by the exciton model . Proc. Natl. Acad. Sci. USA. 93:1996;11640-11645.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11640-11645
    • Packard, B.Z.1    Toptygin, D.D.2    Komoriya, A.3    Brand, L.4
  • 35
    • 0024398164 scopus 로고
    • Activation-driven T cell death I. Requirements for de novo transcription and translation and association with genome fragmentation
    • Ucker D.S., Ashwell J.D., Nickas G. Activation-driven T cell death I. Requirements for de novo transcription and translation and association with genome fragmentation. J. Immunol. 143:1989;3461-3469.
    • (1989) J. Immunol. , vol.143 , pp. 3461-3469
    • Ucker, D.S.1    Ashwell, J.D.2    Nickas, G.3
  • 36
    • 0026595539 scopus 로고
    • Susceptibility to cell death is a dominant phenotype: Triggering of activation-driven T-cell death independent of the T-cell antigen receptor complex
    • Nickas G., Meyers J., Hebshi L.D., Ashwell J.D., Gold D.P., Sydora B., Ucker D.S. Susceptibility to cell death is a dominant phenotype triggering of activation-driven T-cell death independent of the T-cell antigen receptor complex . Mol. Cell. Biol. 12:1992;379-385.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 379-385
    • Nickas, G.1    Meyers, J.2    Hebshi, L.D.3    Ashwell, J.D.4    Gold, D.P.5    Sydora, B.6    Ucker, D.S.7
  • 38
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den Heuvel S., Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science. 262:1993;2050-2054.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van den Heuvel, S.1    Harlow, E.2
  • 39
    • 0029905073 scopus 로고    scopus 로고
    • Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
    • Srinivasula S.M., Ahmad M., Fernandes-Alnemri T., Litwack G., Alnemri E.S. Molecular ordering of the Fas-apoptotic pathway the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases . Proc. Natl. Acad. Sci. USA. 93:1996;14486-14491.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14486-14491
    • Srinivasula, S.M.1    Ahmad, M.2    Fernandes-Alnemri, T.3    Litwack, G.4    Alnemri, E.S.5
  • 40
    • 0030977847 scopus 로고    scopus 로고
    • Target protease specificity of the viral serpin CrmA: Analysis of five caspases
    • Zhou Q., Snipas S., Orth K., Muzio M., Dixit V.M., Saivesen G.S. Target protease specificity of the viral serpin CrmA analysis of five caspases . J. Biol. Chem. 272:1997;7797-7800.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7797-7800
    • Zhou, Q.1    Snipas, S.2    Orth, K.3    Muzio, M.4    Dixit, V.M.5    Saivesen, G.S.6
  • 41
    • 0035500632 scopus 로고    scopus 로고
    • Caspase 8 activity in membrane blebs after anti-Fas ligation
    • Packard B.Z., Komoriya A., Brotz T.M., Henkart P.A. Caspase 8 activity in membrane blebs after anti-Fas ligation. J. Immunol. 167:2001;5061-5066.
    • (2001) J. Immunol. , vol.167 , pp. 5061-5066
    • Packard, B.Z.1    Komoriya, A.2    Brotz, T.M.3    Henkart, P.A.4
  • 42
    • 0036344061 scopus 로고    scopus 로고
    • The effector phase of physiological cell death relies exclusively on the post-translational activation of resident components
    • Chang S.H., Cvetanovic M., Harvey K.J., Komoriya A., Packard B.Z., Ucker D.S. The effector phase of physiological cell death relies exclusively on the post-translational activation of resident components. Exp. Cell Res. 277:2002;15-30.
    • (2002) Exp. Cell Res. , vol.277 , pp. 15-30
    • Chang, S.H.1    Cvetanovic, M.2    Harvey, K.J.3    Komoriya, A.4    Packard, B.Z.5    Ucker, D.S.6
  • 43
    • 0033618445 scopus 로고    scopus 로고
    • +, cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis
    • +, cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis. J. Biol. Chem. 274:1999;21953-21962.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21953-21962
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 44
    • 0035849886 scopus 로고    scopus 로고
    • Phagocytosis promotes programmed cell death in C. elegans
    • Reddien P.W., Cameron S., Horvitz H.R. Phagocytosis promotes programmed cell death in C. elegans. Nature. 412:2001;198-202.
    • (2001) Nature , vol.412 , pp. 198-202
    • Reddien, P.W.1    Cameron, S.2    Horvitz, H.R.3
  • 45
    • 0035849895 scopus 로고    scopus 로고
    • Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans
    • Hoeppner D.J., Hengartner M.O., Schnabel R. Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature. 412:2001;202-206.
    • (2001) Nature , vol.412 , pp. 202-206
    • Hoeppner, D.J.1    Hengartner, M.O.2    Schnabel, R.3
  • 47
    • 0011444717 scopus 로고    scopus 로고
    • Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types
    • Zhang X.D., Nguyen T., Thomas W.D., Sanders J.E., Hersey P. Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types. FEBS Lett. 482:2000;193-199.
    • (2000) FEBS Lett. , vol.482 , pp. 193-199
    • Zhang, X.D.1    Nguyen, T.2    Thomas, W.D.3    Sanders, J.E.4    Hersey, P.5
  • 49
    • 0035901479 scopus 로고    scopus 로고
    • Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage
    • Neuzil J., Schröder A., Weber T., von Hundelshausen P., Zernecke A., Gellert N., Weber C. Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage. Biochemistry. 40:2001;4686-4692.
    • (2001) Biochemistry , vol.40 , pp. 4686-4692
    • Neuzil, J.1    Schröder, A.2    Weber, T.3    Von Hundelshausen, P.4    Zernecke, A.5    Gellert, N.6    Weber, C.7
  • 50
    • 0031929815 scopus 로고    scopus 로고
    • Activation of caspase-3-like enzymes in non-apoptotic T cells
    • Wilhelm S., Wagner H., Häcker G. Activation of caspase-3-like enzymes in non-apoptotic T cells. Eur. J. Immunol. 28:1998;891-900.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 891-900
    • Wilhelm, S.1    Wagner, H.2    Häcker, G.3
  • 51
    • 0033386808 scopus 로고    scopus 로고
    • Caspase activation is required for T cell proliferation
    • Kennedy N.J., Kataoka T., Tschopp J., Budd R.C. Caspase activation is required for T cell proliferation. J. Exp. Med. 190:1999;1891-1895.
    • (1999) J. Exp. Med. , vol.190 , pp. 1891-1895
    • Kennedy, N.J.1    Kataoka, T.2    Tschopp, J.3    Budd, R.C.4
  • 52
    • 0033378016 scopus 로고    scopus 로고
    • Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells
    • Alam A., Cohen L.Y., Aouad S., Sékaly R.-P. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J. Exp. Med. 190:1999;1879-1890.
    • (1999) J. Exp. Med. , vol.190 , pp. 1879-1890
    • Alam, A.1    Cohen, L.Y.2    Aouad, S.3    Sékaly, R.-P.4
  • 55
    • 0029880622 scopus 로고    scopus 로고
    • Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases
    • Meikrantz W., Schlegel R. Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases. J. Biol. Chem. 271:1996; 10205-10209.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10205-10209
    • Meikrantz, W.1    Schlegel, R.2
  • 56
    • 0032529915 scopus 로고    scopus 로고
    • ICAD/DFF regulator of apoptotic nuclease is nuclear
    • Samejima K., Eamshaw W.C. ICAD/DFF regulator of apoptotic nuclease is nuclear. Exp. Cell Res. 243:1998;453-459.
    • (1998) Exp. Cell Res. , vol.243 , pp. 453-459
    • Samejima, K.1    Eamshaw, W.C.2
  • 57
    • 0033020265 scopus 로고    scopus 로고
    • Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosis
    • Buendia B., Santa-Maria A., Courvalin J.C. Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosis. J. Cell Sci. 112:1999;1743-1753.
    • (1999) J. Cell Sci. , vol.112 , pp. 1743-1753
    • Buendia, B.1    Santa-Maria, A.2    Courvalin, J.C.3
  • 58
    • 0034722379 scopus 로고    scopus 로고
    • Caspases disrupt the nuclear-cytoplasmic barrier
    • Faleiro L., Lazebnik Y. Caspases disrupt the nuclear-cytoplasmic barrier. J. Cell Biol. 151:2000;951-959.
    • (2000) J. Cell Biol. , vol.151 , pp. 951-959
    • Faleiro, L.1    Lazebnik, Y.2
  • 59
    • 0034757949 scopus 로고    scopus 로고
    • Sequential degradation of proteins from the nuclear envelope during apoptosis
    • Kihlmark M., Imreh G., Hallberg E. Sequential degradation of proteins from the nuclear envelope during apoptosis. J. Cell Sci. 114:2001;3643-3653.
    • (2001) J. Cell Sci. , vol.114 , pp. 3643-3653
    • Kihlmark, M.1    Imreh, G.2    Hallberg, E.3
  • 60
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Jänicke R.U., Sprengart M.L., Wati M.R., Porter A.G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273:1998;9357-9360.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9357-9360
    • Jänicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 61
    • 0035132464 scopus 로고    scopus 로고
    • Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis
    • Yang X.H., Sladek T.L., Liu X., Butler B.R., Froelich C.J., Thor A.D. Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis. Cancer Res. 61:2001;348-354.
    • (2001) Cancer Res. , vol.61 , pp. 348-354
    • Yang, X.H.1    Sladek, T.L.2    Liu, X.3    Butler, B.R.4    Froelich, C.J.5    Thor, A.D.6
  • 62
    • 0032563286 scopus 로고    scopus 로고
    • Cip1/Waf1 by caspases is an early event during DNA damage-induced apoptosis
    • Cip1/Waf1 by caspases is an early event during DNA damage-induced apoptosis. J. Biol. Chem. 273:1998;19207-19212.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19207-19212
    • Gervais, J.L.M.1    Seth, P.2    Zhang, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.