Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells

Journal of Neuroscience Research

Volumn 59, Issue 5, 2000, Pages 601-611

  Pasquini, Laura A ^a   Besio Moreno, Marcos ^a   Adamo, Ana M ^a   Pasquini, Juana M ^a   Soto, Eduardo F ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Apoptosis; Cell cycle; Cerebellar granule cells; Proteasome inhibition; Ubiquitin

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; DNA FRAGMENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTACYSTIN; PROTEASOME; PROTEIN C FOS; PROTEIN C JUN; PROTEIN P27; PROTEIN P53; UBIQUITIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CEREBELLUM; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GRANULE CELL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; GENE EXPRESSION; MULTIENZYME COMPLEXES; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, WISTAR; UBIQUITINS;

EID: 0342393043     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(20000301)59:5<601::AID-JNR3>3.0.CO;2-1     Document Type: Article

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