-
1
-
-
0031758564
-
Checkpoints on the road to mitosis
-
Russell P. Checkpoints on the road to mitosis. Trends Biochem. Sci. 23 (1998) 399-402
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 399-402
-
-
Russell, P.1
-
2
-
-
17644432403
-
Chk1 is an essential kinase that is regulated by ATR and required for the G(2)/M DNA damage checkpoint
-
Liu Q., Guntuku S., Cui X.S., Matsuoka S., Cortez D., Tamai K., Luo G., Carattini_Rivera S., DeMayo F., Bradley A., Donehower L.A., and Elledge S.J. Chk1 is an essential kinase that is regulated by ATR and required for the G(2)/M DNA damage checkpoint. Genes Dev. 14 (2000) 1448-1459
-
(2000)
Genes Dev.
, vol.14
, pp. 1448-1459
-
-
Liu, Q.1
Guntuku, S.2
Cui, X.S.3
Matsuoka, S.4
Cortez, D.5
Tamai, K.6
Luo, G.7
Carattini-Rivera, S.8
DeMayo, F.9
Bradley, A.10
Donehower, L.A.11
Elledge, S.J.12
-
3
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao H., and Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol. Cell. Biol. 21 (2001) 4129-4139
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
4
-
-
0033634679
-
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
-
Kumagai A., and Dunphy W.G. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol. Cell 6 (2000) 839-849
-
(2000)
Mol. Cell
, vol.6
, pp. 839-849
-
-
Kumagai, A.1
Dunphy, W.G.2
-
5
-
-
0043032435
-
Human Claspin is required for replication checkpoint control
-
Chini C.C., and Chen J. Human Claspin is required for replication checkpoint control. J. Biol. Chem. 278 (2003) 30057-30062
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30057-30062
-
-
Chini, C.C.1
Chen, J.2
-
6
-
-
2342628449
-
Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation
-
Lin S.Y., Li K., Stewart G.S., and Elledge S.J. Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation. Proc. Natl. Acad. Sci. USA 101 (2004) 6484-6489
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6484-6489
-
-
Lin, S.Y.1
Li, K.2
Stewart, G.S.3
Elledge, S.J.4
-
7
-
-
33745860944
-
Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation
-
Bennett L.N., and Clarke P.R. Regulation of Claspin degradation by the ubiquitin-proteosome pathway during the cell cycle and in response to ATR-dependent checkpoint activation. FEBS Lett. 580 (2006) 4176-4781
-
(2006)
FEBS Lett.
, vol.580
, pp. 4176-4781
-
-
Bennett, L.N.1
Clarke, P.R.2
-
8
-
-
33746047485
-
Chk1 is required to maintain claspin stability
-
Chini C.C., Wood J., and Chen J. Chk1 is required to maintain claspin stability. Oncogene 25 (2006) 4165-4171
-
(2006)
Oncogene
, vol.25
, pp. 4165-4171
-
-
Chini, C.C.1
Wood, J.2
Chen, J.3
-
9
-
-
33746429958
-
Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress
-
Mailand N., Bekker-Jensen S., Bartek J., and Lukas J. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Mol. Cell 23 (2006) 307-318
-
(2006)
Mol. Cell
, vol.23
, pp. 307-318
-
-
Mailand, N.1
Bekker-Jensen, S.2
Bartek, J.3
Lukas, J.4
-
10
-
-
33749246225
-
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery
-
Mamely I., van Vugt M.A., Smits V.A., Semple J.I., Lemmens B., Perrakis A., Medema R.H., and Freire R. Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr. Biol. 16 (2006) 1950-1955
-
(2006)
Curr. Biol.
, vol.16
, pp. 1950-1955
-
-
Mamely, I.1
van Vugt, M.A.2
Smits, V.A.3
Semple, J.I.4
Lemmens, B.5
Perrakis, A.6
Medema, R.H.7
Freire, R.8
-
11
-
-
33746413746
-
SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response
-
Peschiaroli A., Dorrello N.V., Guardavaccaro D., Venere M., Halazonetis T., Sherman N.E., and Pagano M. SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol. Cell 23 (2006) 319-329
-
(2006)
Mol. Cell
, vol.23
, pp. 319-329
-
-
Peschiaroli, A.1
Dorrello, N.V.2
Guardavaccaro, D.3
Venere, M.4
Halazonetis, T.5
Sherman, N.E.6
Pagano, M.7
-
12
-
-
0037289840
-
Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
-
Kumagai A., and Dunphy W.G. Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1. Nat. Cell Biol. 5 (2003) 161-165
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 161-165
-
-
Kumagai, A.1
Dunphy, W.G.2
-
13
-
-
20544478438
-
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system
-
Clarke C.A.L., and Clarke P.R. DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. Biochem. J. 388 (2005) 705-712
-
(2005)
Biochem. J.
, vol.388
, pp. 705-712
-
-
Clarke, C.A.L.1
Clarke, P.R.2
-
14
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim S.T., Lim D.S., Canman C.E., and Kastan M.B. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274 (1999) 37538-37543
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.T.1
Lim, D.S.2
Canman, C.E.3
Kastan, M.B.4
-
15
-
-
0033970743
-
Substrate specificity determinants of the checkpoint protein kinase Chk1
-
Hutchins J.R.A., Hughes M., and Clarke P.R. Substrate specificity determinants of the checkpoint protein kinase Chk1. FEBS Lett. 466 (2000) 91-95
-
(2000)
FEBS Lett.
, vol.466
, pp. 91-95
-
-
Hutchins, J.R.A.1
Hughes, M.2
Clarke, P.R.3
-
16
-
-
33845625801
-
Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function
-
Chini C.C., and Chen J. Repeated phosphopeptide motifs in human Claspin are phosphorylated by Chk1 and mediate Claspin function. J. Biol. Chem. 281 (2006) 33276-33282
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 33276-33282
-
-
Chini, C.C.1
Chen, J.2
-
17
-
-
0037415735
-
Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects
-
Zachos G., Rainey M.D., and Gillespie D.A. Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J. 22 (2003) 713-723
-
(2003)
EMBO J.
, vol.22
, pp. 713-723
-
-
Zachos, G.1
Rainey, M.D.2
Gillespie, D.A.3
-
18
-
-
0033581880
-
ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK
-
Hall-Jackson C.A., Cross D.A., Morrice N., and Smythe C. ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK. Oncogene 18 (1999) 6707-6713
-
(1999)
Oncogene
, vol.18
, pp. 6707-6713
-
-
Hall-Jackson, C.A.1
Cross, D.A.2
Morrice, N.3
Smythe, C.4
-
19
-
-
0034655281
-
The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1
-
Busby E.C., Leistritz D.F., Abraham R.T., Karnitz L.M., and Sarkaria J.N. The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. Cancer Res. 60 (2000) 2108-2112
-
(2000)
Cancer Res.
, vol.60
, pp. 2108-2112
-
-
Busby, E.C.1
Leistritz, D.F.2
Abraham, R.T.3
Karnitz, L.M.4
Sarkaria, J.N.5
-
20
-
-
0033975054
-
An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage
-
Jackson J.R., Gilmartin A., Imburgia C., Winkler J.D., Marshall L.A., and Roshak A. An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage. Cancer Res. 60 (2000) 566-572
-
(2000)
Cancer Res.
, vol.60
, pp. 566-572
-
-
Jackson, J.R.1
Gilmartin, A.2
Imburgia, C.3
Winkler, J.D.4
Marshall, L.A.5
Roshak, A.6
-
21
-
-
20244388673
-
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
-
Syljuasen R.G., Sorensen C.S., Hansen L.T., Fugger K., Lundin C., Johansson F., Helleday T., Sehested M., Lukas J., and Bartek J. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol. Cell. Biol. 25 (2005) 3553-3562
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3553-3562
-
-
Syljuasen, R.G.1
Sorensen, C.S.2
Hansen, L.T.3
Fugger, K.4
Lundin, C.5
Johansson, F.6
Helleday, T.7
Sehested, M.8
Lukas, J.9
Bartek, J.10
-
22
-
-
27444446948
-
Cleavage of Claspin by caspase-7 during apoptosis inhibits the Chk1 pathway
-
Clarke C.A.L., Bennett L.N., and Clarke P.R. Cleavage of Claspin by caspase-7 during apoptosis inhibits the Chk1 pathway. J. Biol. Chem. 280 (2005) 35337-35345
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35337-35345
-
-
Clarke, C.A.L.1
Bennett, L.N.2
Clarke, P.R.3
-
23
-
-
34250010317
-
Chk1 regulates the density of active replication origins during the vertebrate S phase
-
Maya-Mendoza A., Petermann E., Gillespie D.A., Caldecott K.W., and Jackson D.A. Chk1 regulates the density of active replication origins during the vertebrate S phase. EMBO J. 26 (2007) 2719-2731
-
(2007)
EMBO J.
, vol.26
, pp. 2719-2731
-
-
Maya-Mendoza, A.1
Petermann, E.2
Gillespie, D.A.3
Caldecott, K.W.4
Jackson, D.A.5
-
24
-
-
33846636785
-
Chk1 is required for spindle checkpoint function
-
Zachos G., Black E.J., Walker M., Scott M.T., Vagnarelli P., Earnshaw W.C., and Gillespie D.A. Chk1 is required for spindle checkpoint function. Dev. Cell 12 (2007) 247-260
-
(2007)
Dev. Cell
, vol.12
, pp. 247-260
-
-
Zachos, G.1
Black, E.J.2
Walker, M.3
Scott, M.T.4
Vagnarelli, P.5
Earnshaw, W.C.6
Gillespie, D.A.7
-
25
-
-
0042698315
-
Lethal errors in checkpoint control life without Chk1
-
Zachos G., Rainey M., and Gillespie D.A. Lethal errors in checkpoint control life without Chk1. Cell Cycle 2 (2003) 14-16
-
(2003)
Cell Cycle
, vol.2
, pp. 14-16
-
-
Zachos, G.1
Rainey, M.2
Gillespie, D.A.3
|