Scale-up of Escherichia coli growth and recombinant protein expression conditions from microwell to laboratory and pilot scale based on matched k La

Biotechnology and Bioengineering

Volumn 99, Issue 5, 2008, Pages 1128-1139

  Islam, R S ^a   Tisi, D ^b   Levy, M S ^c   Lye, G J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ASTEX PHARMACEUTICALS   (United Kingdom)

^c Biogenesis Bago   (Argentina)

Author keywords

E. Coli; Fermentation; k La; Microwell plates; Scale up; Volumetric oxygen transfer coefficient

Indexed keywords

BIOREACTORS; CELL GROWTH; FERMENTATION; PROTEINS; SEWAGE AERATION;

AGITATION; MICROWELL PLATES; SCALE-UP; VOLUMETRIC OXYGEN TRANSFER COEFFICIENT;

ESCHERICHIA COLI;

RECOMBINANT PROTEIN; OXYGEN;

ARTICLE; BIOREACTOR; CELL GROWTH; ESCHERICHIA COLI; FERMENTATION; MICROWELL PLATE; PROTEIN EXPRESSION; SCALE UP; TECHNIQUE; VOLUMETRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; KINETICS; METABOLISM; PILOT STUDY;

ESCHERICHIA COLI;

BIOREACTORS; ESCHERICHIA COLI; FERMENTATION; KINETICS; OXYGEN; PILOT PROJECTS; RECOMBINANT PROTEINS;

EID: 41249099087     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21697     Document Type: Article

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