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Volumn 205, Issue 3, 2008, Pages 669-684

A gammaherpesvirus-secreted activator of Vβ4+ CD8 + T cells regulates chronic infection and immunopathology

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; PROTEIN M1; SUPERANTIGEN; UNCLASSIFIED DRUG;

EID: 41149141391     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20071135     Document Type: Article
Times cited : (55)

References (78)
  • 1
    • 0004250845 scopus 로고    scopus 로고
    • Knipe, D.M, P.M. Howley, D.E. Griffin, R.A. Lamb, S.E. Straus, M.A. Martin, and B. Roizman, editors, Lippincott Williams and Wilkins, Philadelphia
    • Knipe, D.M., P.M. Howley, D.E. Griffin, R.A. Lamb, S.E. Straus, M.A. Martin, and B. Roizman, editors. 2007. Fields Virology. Lippincott Williams and Wilkins, Philadelphia.
    • (2007) Fields Virology
  • 3
    • 13644265957 scopus 로고    scopus 로고
    • On phylogenetic relationships among major lineages of the Gammaherpesvirinae
    • McGeoch, D.J., D. Gatherer, and A. Dolan. 2005. On phylogenetic relationships among major lineages of the Gammaherpesvirinae. J. Gen. Virol. 86:307-316.
    • (2005) J. Gen. Virol , vol.86 , pp. 307-316
    • McGeoch, D.J.1    Gatherer, D.2    Dolan, A.3
  • 4
    • 0033179090 scopus 로고    scopus 로고
    • Host and viral genetics of chronic infection: A mouse model of gamma-herpesvirus pathogenesis
    • Speck, S.H., and H.W. Virgin. 1999. Host and viral genetics of chronic infection: a mouse model of gamma-herpesvirus pathogenesis. Curr. Opin. Microbiol. 2:403-409.
    • (1999) Curr. Opin. Microbiol , vol.2 , pp. 403-409
    • Speck, S.H.1    Virgin, H.W.2
  • 5
    • 0033178351 scopus 로고    scopus 로고
    • Unraveling immunity to gamma-herpesviruses: A new model for understanding the role of immunity in chronic virus infection
    • Virgin, H.W., and S.H. Speck. 1999. Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection. Curr. Opin. Immunol. 11:371-379.
    • (1999) Curr. Opin. Immunol , vol.11 , pp. 371-379
    • Virgin, H.W.1    Speck, S.H.2
  • 6
    • 0030979780 scopus 로고    scopus 로고
    • Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: A role for CD8 T cells
    • Dutia, B.M., C.J. Clarke, D.J. Allen, and A.A. Nash. 1997. Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: a role for CD8 T cells. J. Virol. 71:4278-4283.
    • (1997) J. Virol , vol.71 , pp. 4278-4283
    • Dutia, B.M.1    Clarke, C.J.2    Allen, D.J.3    Nash, A.A.4
  • 8
    • 34249785699 scopus 로고    scopus 로고
    • Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner
    • Steed, A., T. Buch, A. Waisman, and H.W. Virgin. 2007. Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner. J. Virol. 81:6134-6140.
    • (2007) J. Virol , vol.81 , pp. 6134-6140
    • Steed, A.1    Buch, T.2    Waisman, A.3    Virgin, H.W.4
  • 9
    • 0034970621 scopus 로고    scopus 로고
    • Murine gammaherpesvirus-68 infection causes multi-organ fibrosis and alters leukocyte trafficking in interferon-gamma receptor knockout mice
    • Ebrahimi, B., B.M. Dutia, D.G. Brownstein, and A.A. Nash. 2001. Murine gammaherpesvirus-68 infection causes multi-organ fibrosis and alters leukocyte trafficking in interferon-gamma receptor knockout mice. Am. J. Pathol. 158:2117-2125.
    • (2001) Am. J. Pathol , vol.158 , pp. 2117-2125
    • Ebrahimi, B.1    Dutia, B.M.2    Brownstein, D.G.3    Nash, A.A.4
  • 13
    • 0031464609 scopus 로고    scopus 로고
    • Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: A new model for virus-induced vascular disease
    • Weck, K.E., A.J. Dal Canto, J.D. Gould, A.K. O'Guin, K.A. Roth, J.E. Saffitz, S.H. Speck, and H.W. Virgin. 1997. Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Nat. Med. 3:1346-1353.
    • (1997) Nat. Med , vol.3 , pp. 1346-1353
    • Weck, K.E.1    Dal Canto, A.J.2    Gould, J.D.3    O'Guin, A.K.4    Roth, K.A.5    Saffitz, J.E.6    Speck, S.H.7    Virgin, H.W.8
  • 14
    • 0035143510 scopus 로고    scopus 로고
    • IFN-gamma action in the media of the great elastic arteries, a novel immunoprivileged site
    • Dal Canto, A.J., P.E. Swanson, A.K. O'Guin, S.H. Speck, and H.W. Virgin. 2001. IFN-gamma action in the media of the great elastic arteries, a novel immunoprivileged site. J. Clin. Invest. 107:R15-R22.
    • (2001) J. Clin. Invest , vol.107
    • Dal Canto, A.J.1    Swanson, P.E.2    O'Guin, A.K.3    Speck, S.H.4    Virgin, H.W.5
  • 15
    • 0034468078 scopus 로고    scopus 로고
    • Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage
    • Dal Canto, A.J., H.W. Virgin, and S.H. Speck. 2000. Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage. J. Virol. 74:11304-11310.
    • (2000) J. Virol , vol.74 , pp. 11304-11310
    • Dal Canto, A.J.1    Virgin, H.W.2    Speck, S.H.3
  • 16
    • 0033948614 scopus 로고    scopus 로고
    • Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency
    • Clambey, E.T., H.W. Virgin, and S.H. Speck. 2000. Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency. J. Virol. 74:1973-1984.
    • (2000) J. Virol , vol.74 , pp. 1973-1984
    • Clambey, E.T.1    Virgin, H.W.2    Speck, S.H.3
  • 17
    • 0036281954 scopus 로고    scopus 로고
    • Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpes-virus 68 reveals tissue-specific genetic requirements for latency
    • Clambey, E.T., H.W. Virgin, and S.H. Speck. 2002. Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpes-virus 68 reveals tissue-specific genetic requirements for latency. J. Virol. 76:6532-6544.
    • (2002) J. Virol , vol.76 , pp. 6532-6544
    • Clambey, E.T.1    Virgin, H.W.2    Speck, S.H.3
  • 18
    • 30144443612 scopus 로고    scopus 로고
    • The M4 gene of gammaHV68 encodes a secreted glycoprotein and is required for the efficient establishment of splenic latency
    • Evans, A.G., N.J. Moorman, D.O. Willer, and S.H. Speck. 2006. The M4 gene of gammaHV68 encodes a secreted glycoprotein and is required for the efficient establishment of splenic latency. Virology. 344:520-531.
    • (2006) Virology , vol.344 , pp. 520-531
    • Evans, A.G.1    Moorman, N.J.2    Willer, D.O.3    Speck, S.H.4
  • 19
    • 13444266320 scopus 로고    scopus 로고
    • The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells
    • Herskowitz, J., M.A. Jacoby, and S.H. Speck. 2005. The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells. J. Virol. 79:2261-2273.
    • (2005) J. Virol , vol.79 , pp. 2261-2273
    • Herskowitz, J.1    Jacoby, M.A.2    Speck, S.H.3
  • 20
    • 0036146179 scopus 로고    scopus 로고
    • Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation
    • Jacoby, M.A., H.W. Virgin, and S.H. Speck. 2002. Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation. J. Virol. 76:1790-1801.
    • (2002) J. Virol , vol.76 , pp. 1790-1801
    • Jacoby, M.A.1    Virgin, H.W.2    Speck, S.H.3
  • 22
    • 0036218112 scopus 로고    scopus 로고
    • Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis
    • van Berkel, V., B. Levine, S.B. Kapadia, J.E. Goldman, S.H. Speck, and H.W. Virgin. 2002. Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis. J. Clin. Invest. 109:905-914.
    • (2002) J. Clin. Invest , vol.109 , pp. 905-914
    • van Berkel, V.1    Levine, B.2    Kapadia, S.B.3    Goldman, J.E.4    Speck, S.H.5    Virgin, H.W.6
  • 23
    • 0347319105 scopus 로고    scopus 로고
    • The m4 gene of murine gammaherpesvirus modulates productive and latent infection in vivo
    • Townsley, A.C., B.M. Dutia, and A.A. Nash. 2004. The m4 gene of murine gammaherpesvirus modulates productive and latent infection in vivo. J. Virol. 78:758-767.
    • (2004) J. Virol , vol.78 , pp. 758-767
    • Townsley, A.C.1    Dutia, B.M.2    Nash, A.A.3
  • 24
    • 0029811734 scopus 로고    scopus 로고
    • Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells
    • Cardin, R.D., J.W. Brooks, S.R. Sarawar, and P.C. Doherty. 1996. Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells. J. Exp. Med. 184:863-871.
    • (1996) J. Exp. Med , vol.184 , pp. 863-871
    • Cardin, R.D.1    Brooks, J.W.2    Sarawar, S.R.3    Doherty, P.C.4
  • 25
    • 0027179405 scopus 로고
    • Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells
    • Ehtisham, S., N.P. Sunil-Chandra, and A.A. Nash. 1993. Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells. J. Virol. 67:5247-5252.
    • (1993) J. Virol , vol.67 , pp. 5247-5252
    • Ehtisham, S.1    Sunil-Chandra, N.P.2    Nash, A.A.3
  • 27
    • 0032751735 scopus 로고    scopus 로고
    • T-cell vaccination alters the course of murine herpesvirus 68 infection and the establishment of viral latency in mice
    • Liu, L., E.J. Usherwood, M.A. Blackman, and D.L. Woodland. 1999. T-cell vaccination alters the course of murine herpesvirus 68 infection and the establishment of viral latency in mice. J. Virol. 73:9849-9857.
    • (1999) J. Virol , vol.73 , pp. 9849-9857
    • Liu, L.1    Usherwood, E.J.2    Blackman, M.A.3    Woodland, D.L.4
  • 29
    • 1642536435 scopus 로고    scopus 로고
    • Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection
    • Obar, J.J., S.G. Crist, D.C. Gondek, and E.J. Usherwood. 2004. Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection. J. Immunol. 172:1213-1219.
    • (2004) J. Immunol , vol.172 , pp. 1213-1219
    • Obar, J.J.1    Crist, S.G.2    Gondek, D.C.3    Usherwood, E.J.4
  • 30
    • 33748482479 scopus 로고    scopus 로고
    • Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection
    • Obar, J.J., S. Fuse, E.K. Leung, S.C. Bellfy, and E.J. Usherwood. 2006. Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. J. Virol. 80:8303-8315.
    • (2006) J. Virol , vol.80 , pp. 8303-8315
    • Obar, J.J.1    Fuse, S.2    Leung, E.K.3    Bellfy, S.C.4    Usherwood, E.J.5
  • 31
    • 0032938752 scopus 로고    scopus 로고
    • Changing patterns of dominance in the CD8+ T cell response during acute and persistent murine gamma-herpesvirus infection
    • Stevenson, P.G., G.T. Belz, J.D. Altman, and P.C. Doherty. 1999. Changing patterns of dominance in the CD8+ T cell response during acute and persistent murine gamma-herpesvirus infection. Eur. J. Immunol. 29:1059-1067.
    • (1999) Eur. J. Immunol , vol.29 , pp. 1059-1067
    • Stevenson, P.G.1    Belz, G.T.2    Altman, J.D.3    Doherty, P.C.4
  • 35
    • 0033674936 scopus 로고    scopus 로고
    • Murine gamma-herpesvirus-68: A mouse model for infectious mononucleosis?
    • Blackman, M.A., E. Flano, E. Usherwood, and D.L. Woodland. 2000. Murine gamma-herpesvirus-68: a mouse model for infectious mononucleosis? Mol. Med. Today. 6:488-490.
    • (2000) Mol. Med. Today , vol.6 , pp. 488-490
    • Blackman, M.A.1    Flano, E.2    Usherwood, E.3    Woodland, D.L.4
  • 36
    • 0032862286 scopus 로고    scopus 로고
    • Requirement for CD40 ligand, CD4(+) T cells, and B cells in an infectious mononucleosis-like syndrome
    • Brooks, J.W., A.M. Hamilton-Easton, J.P. Christensen, R.D. Cardin, C.L. Hardy, and P.C. Doherty. 1999. Requirement for CD40 ligand, CD4(+) T cells, and B cells in an infectious mononucleosis-like syndrome. J. Virol. 73:9650-9654.
    • (1999) J. Virol , vol.73 , pp. 9650-9654
    • Brooks, J.W.1    Hamilton-Easton, A.M.2    Christensen, J.P.3    Cardin, R.D.4    Hardy, C.L.5    Doherty, P.C.6
  • 38
    • 1642421746 scopus 로고    scopus 로고
    • Forced lytic replication impairs host colonization by a latencydefi cient mutant of murine gammaherpesvirus-68
    • May, J.S., H.M. Coleman, B. Smillie, S. Efstathiou, and P.G. Stevenson. 2004. Forced lytic replication impairs host colonization by a latencydefi cient mutant of murine gammaherpesvirus-68. J. Gen. Virol. 85: 137-146.
    • (2004) J. Gen. Virol , vol.85 , pp. 137-146
    • May, J.S.1    Coleman, H.M.2    Smillie, B.3    Efstathiou, S.4    Stevenson, P.G.5
  • 39
  • 40
    • 0033858509 scopus 로고    scopus 로고
    • Murine gamma-herpesvirus infection causes V(beta)4-specific CDR3-restricted clonal expansions within CD8(+) peripheral blood T lymphocytes
    • Hardy, C.L., S.L. Silins, D.L. Woodland, and M.A. Blackman. 2000. Murine gamma-herpesvirus infection causes V(beta)4-specific CDR3-restricted clonal expansions within CD8(+) peripheral blood T lymphocytes. Int. Immunol. 12:1193-1204.
    • (2000) Int. Immunol , vol.12 , pp. 1193-1204
    • Hardy, C.L.1    Silins, S.L.2    Woodland, D.L.3    Blackman, M.A.4
  • 42
    • 0030808292 scopus 로고    scopus 로고
    • Murine gammaherpesvirus 68 encodes tRNA-like sequences which are expressed during latency
    • Bowden, R.J., J.P. Simas, A.J. Davis, and S. Efstathiou. 1997. Murine gammaherpesvirus 68 encodes tRNA-like sequences which are expressed during latency. J. Gen. Virol. 78( Pt 7 ):1675-1687.
    • (1997) J. Gen. Virol , vol.78 , Issue.PART 7 , pp. 1675-1687
    • Bowden, R.J.1    Simas, J.P.2    Davis, A.J.3    Efstathiou, S.4
  • 43
    • 0031963624 scopus 로고    scopus 로고
    • Four tRNA-like sequences and a serpin homologue encoded by murine gammaherpesvirus 68 are dispensable for lytic replication in vitro and latency in vivo
    • Simas, J.P., R.J. Bowden, V. Paige, and S. Efstathiou. 1998. Four tRNA-like sequences and a serpin homologue encoded by murine gammaherpesvirus 68 are dispensable for lytic replication in vitro and latency in vivo. J. Gen. Virol. 79( Pt 1 ):149-153.
    • (1998) J. Gen. Virol , vol.79 , Issue.PART 1 , pp. 149-153
    • Simas, J.P.1    Bowden, R.J.2    Paige, V.3    Efstathiou, S.4
  • 45
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech, S.M., J.T. Tan, E.J. Wherry, B.T. Konieczny, C.D. Surh, and R. Ahmed. 2003. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4:1191-1198.
    • (2003) Nat. Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 46
    • 0036167033 scopus 로고    scopus 로고
    • CD94-NKG2A receptors regulate antiviral CD8(+) T cell responses
    • Moser, J.M., J. Gibbs, P.E. Jensen, and A.E. Lukacher. 2002. CD94-NKG2A receptors regulate antiviral CD8(+) T cell responses. Nat. Immunol. 3:189-195.
    • (2002) Nat. Immunol , vol.3 , pp. 189-195
    • Moser, J.M.1    Gibbs, J.2    Jensen, P.E.3    Lukacher, A.E.4
  • 48
    • 0032928080 scopus 로고    scopus 로고
    • Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein
    • van Berkel, V., K. Preiter, H.W. Virgin, and S.H. Speck. 1999. Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein. J. Virol. 73:4524-4529.
    • (1999) J. Virol , vol.73 , pp. 4524-4529
    • van Berkel, V.1    Preiter, K.2    Virgin, H.W.3    Speck, S.H.4
  • 50
    • 0029127646 scopus 로고
    • Enhanced HIV-1 replication in V beta 12 T cells due to human cytomegalovirus in monocytes: Evidence for a putative herpesvirus superantigen
    • Dobrescu, D., B. Ursea, M. Pope, A.S. Asch, and D.N. Posnett. 1995. Enhanced HIV-1 replication in V beta 12 T cells due to human cytomegalovirus in monocytes: evidence for a putative herpesvirus superantigen. Cell. 82:753-763.
    • (1995) Cell , vol.82 , pp. 753-763
    • Dobrescu, D.1    Ursea, B.2    Pope, M.3    Asch, A.S.4    Posnett, D.N.5
  • 51
    • 0025865438 scopus 로고
    • A superantigen encoded in the open reading frame of the 3′ - long terminal repeat of mouse mammary tumour virus
    • Choi, Y., J.W. Kappler, and P. Marrack. 1991. A superantigen encoded in the open reading frame of the 3′ - long terminal repeat of mouse mammary tumour virus. Nature. 350:203-207.
    • (1991) Nature , vol.350 , pp. 203-207
    • Choi, Y.1    Kappler, J.W.2    Marrack, P.3
  • 52
    • 0026029670 scopus 로고
    • A maternally inherited superantigen encoded by a mammary tumour virus
    • Marrack, P., E. Kushnir, and J. Kappler. 1991. A maternally inherited superantigen encoded by a mammary tumour virus. Nature. 349:524-526.
    • (1991) Nature , vol.349 , pp. 524-526
    • Marrack, P.1    Kushnir, E.2    Kappler, J.3
  • 54
    • 0029994686 scopus 로고    scopus 로고
    • Herpesvirus saimiri open reading frame 14, a protein encoded by T lymphotropic herpesvirus, binds to MHC class II molecules and stimulates T cell proliferation
    • Yao, Z., E. Maraskovsky, M.K. Spriggs, J.I. Cohen, R.J. Armitage, and M.R. Alderson. 1996. Herpesvirus saimiri open reading frame 14, a protein encoded by T lymphotropic herpesvirus, binds to MHC class II molecules and stimulates T cell proliferation. J. Immunol. 156:3260-3266.
    • (1996) J. Immunol , vol.156 , pp. 3260-3266
    • Yao, Z.1    Maraskovsky, E.2    Spriggs, M.K.3    Cohen, J.I.4    Armitage, R.J.5    Alderson, M.R.6
  • 56
    • 0028916686 scopus 로고
    • Direct binding of the Mtv7 superantigen (Mls-1) to soluble MHC class II molecules
    • Mottershead, D.G., P.N. Hsu, R.G. Urban, J.L. Strominger, and B.T. Huber. 1995. Direct binding of the Mtv7 superantigen (Mls-1) to soluble MHC class II molecules. Immunity. 2:149-154.
    • (1995) Immunity , vol.2 , pp. 149-154
    • Mottershead, D.G.1    Hsu, P.N.2    Urban, R.G.3    Strominger, J.L.4    Huber, B.T.5
  • 57
    • 33746025600 scopus 로고    scopus 로고
    • Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway
    • Bueno, C., C.D. Lemke, G. Criado, M.L. Baroja, S.S. Ferguson, A.K. Rahman, C.D. Tsoukas, J.K. McCormick, and J. Madrenas. 2006. Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. Immunity. 25:67-78.
    • (2006) Immunity , vol.25 , pp. 67-78
    • Bueno, C.1    Lemke, C.D.2    Criado, G.3    Baroja, M.L.4    Ferguson, S.S.5    Rahman, A.K.6    Tsoukas, C.D.7    McCormick, J.K.8    Madrenas, J.9
  • 58
    • 0033568586 scopus 로고    scopus 로고
    • Requirement for CD4+ T cells in V beta 4+CD8+ T cell activation associated with latent murine gammaherpesvirus infection
    • Flano, E., D.L. Woodland, and M.A. Blackman. 1999. Requirement for CD4+ T cells in V beta 4+CD8+ T cell activation associated with latent murine gammaherpesvirus infection. J. Immunol. 163:3403-3408.
    • (1999) J. Immunol , vol.163 , pp. 3403-3408
    • Flano, E.1    Woodland, D.L.2    Blackman, M.A.3
  • 59
    • 0036635343 scopus 로고    scopus 로고
    • Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus
    • Tibbetts, S.A., L.F. van Dyk, S.H. Speck, and H.W. Virgin. 2002. Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus. J. Virol. 76:7125-7132.
    • (2002) J. Virol , vol.76 , pp. 7125-7132
    • Tibbetts, S.A.1    van Dyk, L.F.2    Speck, S.H.3    Virgin, H.W.4
  • 61
    • 2942693575 scopus 로고    scopus 로고
    • An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection
    • Sparks-Thissen, R.L., D.C. Braaten, S. Kreher, S.H. Speck, and H.W. Virgin. 2004. An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection. J. Virol. 78:6827-6835.
    • (2004) J. Virol , vol.78 , pp. 6827-6835
    • Sparks-Thissen, R.L.1    Braaten, D.C.2    Kreher, S.3    Speck, S.H.4    Virgin, H.W.5
  • 63
    • 34247884612 scopus 로고    scopus 로고
    • The function of programmed cell death 1 and its ligands in regulating auto-immunity and infection
    • Sharpe, A.H., E.J. Wherry, R. Ahmed, and G.J. Freeman. 2007. The function of programmed cell death 1 and its ligands in regulating auto-immunity and infection. Nat. Immunol. 8:239-245.
    • (2007) Nat. Immunol , vol.8 , pp. 239-245
    • Sharpe, A.H.1    Wherry, E.J.2    Ahmed, R.3    Freeman, G.J.4
  • 64
    • 33746617565 scopus 로고    scopus 로고
    • Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses
    • McClellan, K.B., S. Gangappa, S.H. Speck, and H.W. Virgin. 2006. Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses. PLoS Pathog. 2:e58.
    • (2006) PLoS Pathog , vol.2
    • McClellan, K.B.1    Gangappa, S.2    Speck, S.H.3    Virgin, H.W.4
  • 65
    • 0038806366 scopus 로고    scopus 로고
    • Selective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes
    • Marques, S., S. Efstathiou, K.G. Smith, M. Haury, and J.P. Simas. 2003. Selective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes. J. Virol. 77:7308-7318.
    • (2003) J. Virol , vol.77 , pp. 7308-7318
    • Marques, S.1    Efstathiou, S.2    Smith, K.G.3    Haury, M.4    Simas, J.P.5
  • 66
    • 34249064632 scopus 로고    scopus 로고
    • Epstein-Barr virus
    • D.M. Knipe and P.M. Howley, editors. Lippincott Williams and Wilkins, Philadelphia. pp
    • Rickinson, A.B., and E. Kieff. 2007. Epstein-Barr virus. In Fields Virology. D.M. Knipe and P.M. Howley, editors. Lippincott Williams and Wilkins, Philadelphia. pp. 2655-2700.
    • (2007) Fields Virology , pp. 2655-2700
    • Rickinson, A.B.1    Kieff, E.2
  • 67
    • 0033061214 scopus 로고    scopus 로고
    • B cells regulate murine gammaherpesvirus 68 latency
    • Weck, K.E., S.S. Kim, H.I. Virgin, and S.H. Speck. 1999. B cells regulate murine gammaherpesvirus 68 latency. J. Virol. 73:4651-4661.
    • (1999) J. Virol , vol.73 , pp. 4651-4661
    • Weck, K.E.1    Kim, S.S.2    Virgin, H.I.3    Speck, S.H.4
  • 68
    • 37849044580 scopus 로고    scopus 로고
    • Murine gammaherpesvirus 68 genes both induce and suppress lymphoproliferative disease
    • Tarakanova, V.L., F. Kreisel, D.W. White, and H.W. Virgin. 2007. Murine gammaherpesvirus 68 genes both induce and suppress lymphoproliferative disease. J. Virol. 82:1034-1039.
    • (2007) J. Virol , vol.82 , pp. 1034-1039
    • Tarakanova, V.L.1    Kreisel, F.2    White, D.W.3    Virgin, H.W.4
  • 69
    • 0034750690 scopus 로고    scopus 로고
    • Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen
    • Sutkowski, N., B. Conrad, D.A. Thorley-Lawson, and B.T. Huber. 2001. Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen. Immunity. 15:579-589.
    • (2001) Immunity , vol.15 , pp. 579-589
    • Sutkowski, N.1    Conrad, B.2    Thorley-Lawson, D.A.3    Huber, B.T.4
  • 70
    • 3142767678 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen
    • Sutkowski, N., G. Chen, G. Calderon, and B.T. Huber. 2004. Epstein-Barr virus latent membrane protein LMP-2A is sufficient for transactivation of the human endogenous retrovirus HERV-K18 superantigen. J. Virol. 78:7852-7860.
    • (2004) J. Virol , vol.78 , pp. 7852-7860
    • Sutkowski, N.1    Chen, G.2    Calderon, G.3    Huber, B.T.4
  • 71
    • 33746901071 scopus 로고    scopus 로고
    • Murine Vbeta3+ and Vbeta7+ T cell subsets are specific targets for the HERV-K18 Env superantigen
    • Tai, A.K., M. Lin, F. Chang, G. Chen, F. Hsiao, N. Sutkowski, and B.T. Huber. 2006. Murine Vbeta3+ and Vbeta7+ T cell subsets are specific targets for the HERV-K18 Env superantigen. J. Immunol. 177:3178-3184.
    • (2006) J. Immunol , vol.177 , pp. 3178-3184
    • Tai, A.K.1    Lin, M.2    Chang, F.3    Chen, G.4    Hsiao, F.5    Sutkowski, N.6    Huber, B.T.7
  • 72
    • 34247892632 scopus 로고    scopus 로고
    • Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules
    • Ma, C.S., K.E. Nichols, and S.G. Tangye. 2007. Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules. Annu. Rev. Immunol. 25:337-379.
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 337-379
    • Ma, C.S.1    Nichols, K.E.2    Tangye, S.G.3
  • 73
    • 33750385770 scopus 로고    scopus 로고
    • Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease
    • Crotty, S., M.M. McCausland, R.D. Aubert, E.J. Wherry, and R. Ahmed. 2006. Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease. Blood. 108:3085-3093.
    • (2006) Blood , vol.108 , pp. 3085-3093
    • Crotty, S.1    McCausland, M.M.2    Aubert, R.D.3    Wherry, E.J.4    Ahmed, R.5
  • 74
    • 23444433656 scopus 로고    scopus 로고
    • Signaling lymphocyte activation molecule-associated protein is a negative regulator of the CD8 T cell response in mice
    • Chen, G., A.K. Tai, M. Lin, F. Chang, C. Terhorst, and B.T. Huber. 2005. Signaling lymphocyte activation molecule-associated protein is a negative regulator of the CD8 T cell response in mice. J. Immunol. 175:2212-2218.
    • (2005) J. Immunol , vol.175 , pp. 2212-2218
    • Chen, G.1    Tai, A.K.2    Lin, M.3    Chang, F.4    Terhorst, C.5    Huber, B.T.6
  • 75
    • 0141535212 scopus 로고    scopus 로고
    • Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia
    • Yin, L., U. Al-Alem, J. Liang, W.M. Tong, C. Li, M. Badiali, J.J. Medard, J. Sumegi, Z.Q. Wang, and G. Romeo. 2003. Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia. J. Med. Virol. 71:446-455.
    • (2003) J. Med. Virol , vol.71 , pp. 446-455
    • Yin, L.1    Al-Alem, U.2    Liang, J.3    Tong, W.M.4    Li, C.5    Badiali, M.6    Medard, J.J.7    Sumegi, J.8    Wang, Z.Q.9    Romeo, G.10
  • 76
    • 0141856355 scopus 로고    scopus 로고
    • The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency
    • Moorman, N.J., D.O. Willer, and S.H. Speck. 2003. The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency. J. Virol. 77:10295-10303.
    • (2003) J. Virol , vol.77 , pp. 10295-10303
    • Moorman, N.J.1    Willer, D.O.2    Speck, S.H.3
  • 77
    • 0033912858 scopus 로고    scopus 로고
    • Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome
    • Adler, H., M. Messerle, M. Wagner, and U.H. Koszinowski. 2000. Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome. J. Virol. 74:6964-6974.
    • (2000) J. Virol , vol.74 , pp. 6964-6974
    • Adler, H.1    Messerle, M.2    Wagner, M.3    Koszinowski, U.H.4
  • 78
    • 0029817996 scopus 로고    scopus 로고
    • Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68
    • Weck, K.E., M.L. Barkon, L.I. Yoo, S.H. Speck, and H.I. Virgin. 1996. Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. J. Virol. 70:6775-6780.
    • (1996) J. Virol , vol.70 , pp. 6775-6780
    • Weck, K.E.1    Barkon, M.L.2    Yoo, L.I.3    Speck, S.H.4    Virgin, H.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.