IFN-γ action in the media of the great elastic arteries, a novel immunoprivileged site

Journal of Clinical Investigation

Volumn 107, Issue 2, 2001, Pages

  Dal Canto, Albert J ^a   Swanson, Paul E ^a   O'Guin, Andrew K ^a   Speck, Samuel H ^a   Virgin, Herbert W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DISEASE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GREAT BLOOD VESSEL; HEMATOPOIETIC CELL; HERPES VIRUS; IMMUNE RESPONSE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE; SOMATIC CELL; T LYMPHOCYTE; TUNICA MEDIA; VIRUS INFECTION; VIRUS STRAIN;

EID: 0035143510     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI11540     Document Type: Article

References (42)

1. Murine gammaherpesvirus 68 causes large vessel arteritis in mice lacking interferon-gamma responsiveness: A new model for virus induced vascular disease
2. Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage
3. Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouse
4. Interferon-gamma deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts
5. IFN-gamma potentiates atherosclerosis in apoE knock-out mice
6. Interferon-gamma regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels
7. Interferon-gamma elicits arteriosclerosis in the absence of leukocytes
8. Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency
9. The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency
10. Functional role of type I and type II interferons in antiviral defense
11. Isolation of a cell line for rapid and sensitive hisrochemical assay for the detection of herpes simplex virus
12. Role of immune cells in protection against and control of teovitus infection in neonatal mice
13. F4/80, a monoclonal antibody directed specifically against the mouse macrophage
14. Immune response in mice that lack the interferon-gamma receptor
15. Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection
16. The T cell independent role of IFN-gamma and TNF-alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infection
17. Aortic endothelial and smooth muscle cell cultures
18. Functional angiotensin II receptors in cultured vascular smooth muscle cells
19. Autoimmune vasculitis resulting from in vitro immunization of lymphocytes to smooth muscle
20. Persistence of viruses
21. CTL access to tissue antigen is restricted in vivo
22. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
23. Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion
24. A lamellar unit of aortic medial structure and function in mammals
25. Nature of species differences in the medial distribution of aortic vasa vasorum in mammals
26. Comparison of abdominal and thoracic aortic medial structure in mammals. Deviation of man from the usual pattern
27. Immunohistochemical characterization of inflammatory cells associated with advanced atherosclerosis
28. Characterization of inflammatory cells in a patient with chronic periaortitis
29. The spectrum of chronic periaortitis
30. Interferon-gamma-producing T cells in giant cell vasculitis represent a minority of tissue-infiltrating cells and are located distant from the site of pathology
31. A broad spectrum secreted chemokine binding protein encoded by a herpesvirus
32. Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action
33. Murine gammaherpesvirus 68 encodes a functional regulator of complement activation
34. Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes
35. Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes
36. Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands
37. An essential role for type 1 interferon-gamma in terminating persistent viral infection
38. Low-affinity cytotoxic T-lymphocytes require IFN-gamma to clear an acute viral infection
39. A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers
40. Cyrokines in the generation of immune responses to, and resolution of, virus infection
41. How cells respond to interferons
42. Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)- alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii