Changing patterns of dominance in the CD8+ T cell response during acute and persistent murine γ-herpesvirus infection

European Journal of Immunology

Volumn 29, Issue 4, 1999, Pages 1059-1067

  Stevenson, Philip G ^a   Belz, Gabrielle T ^a   Altman, John D ^b   Doherty, Peter C ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD8+ T cell; Epitope; Herpesvirus; Mononucleosis

Indexed keywords

CD8 ANTIGEN; EPITOPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; HERPES VIRUS; INFECTIOUS MONONUCLEOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0032938752     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199904)29:04<1059::AID-IMMU1059>3.0.CO;2-L     Document Type: Article

References (35)

1. Levitskaya, J., Coram, M., Levitsky, V., Imreh, S., Steigerwald-Mullen, P. M., Klein, G., Kurilla, M. G. and Masucci, M. G., Inhibition of antigen processing by the internal repeat of the Epstein-Barr virus nuclear antigen-1. Nature 1995. 375: 685-688.
2. Ploegh, H. L., Viral strategies of immune evasion. Science 1998. 280: 248-253.
3. Hsu, D. H., de Waal Malefyt, R., Florentino, D. F., Dang, M. N., Viera, P., de Vries, J., Spits, H., Mosmann, T. R. and Moore, K. W., Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science 1990. 250: 830-832.
4. Moore, P. S., Boshoff, C., Weiss, R. A. and Chang, Y., Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 1996. 274: 1739-1744.
5. + T cell during the primary immune response to Epstein-Barr virus in vivo. J. Exp. Med. 1998. 187: 1395-1402.
6. Rajcani, J., Blaskovic, D., Svobodova, J., Ciampor, F., Huckova, D. and Stanekova, D., Pathogenesis of acute and persistent murine herpesvirus infection in mice. Acta. Virol. 1985. 29: 51-60.
7. Efstathiou, S., Ho, Y. M., Hall, S., Styles, C. J., Scott, S. D. and Gompels, U. A., Murine herpesvirus 68 is genetically related to the γ-herpesviruses Epstein-Barr virus and Herpesvirus saimiri. J. Gen. Virol. 1990. 71: 1365-1372.
8. Virgin, H. W. IV, Latrielle, P., Wamsley, P., Hallsworth, K., Weck, K. E., Dal Canto, A. J. and Speck, S. H., Complete sequence and genomic analysis of murine γ-herpesvirus 68. J. Virol. 1997. 71: 589-5904.
9. Usherwood, E. J., Stewart, J. P., Robertson, K., Allen, D. J. and Nash, A. A., Absence of splenic latency in murine γ-herpesvirus 68-infected B cell-deficient mice. J. Gen. Virol. 1996. 77: 2819-2825.
10. Sunil-Chandra, N. P., Efstathiou, S. and Nash, A. A., Murine γ-herpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. J. Gen. Virol. 1992. 73: 3275-3279.
11. Ehtisham, S., Sunil-Chandra, N. P. and Nash, A. A., Pathogenesis of murine γ-herpesvirus infection in mice deficient in CD4 and CD8 T cells. J. Virol. 1993. 67: 5247-5252.
12. Weck, K. E., Barkon, M. L., Yoo, L. I., Speck, S. H. and Virgin, H. W. IV, Mature B cells are required for acute splenic infection but not for establishment of latency by murine γ-herpesvirus 68. J. Virol. 1996. 70: 6775-6780.
13. Nash, A. A. and Sunil-Chandra, N. P., Interactions of the murine γ-herpesvirus with the immune system. Curr. Opin. Immunol. 1994. 6: 560-563.
14. Doherty, P. C., Tripp, R. A., Hamilton-Easton, A. M., Cardin, R. D., Woodland, D. L. and Blackman, M. A., Tuning into immunological dissonance: an experimental model for infectious mononucleosis. Curr. Opin. Immunol. 1997. 9: 477-483.
15. Tripp, R. A., Hamilton-Easton, A. M., Cardin, R. D., Nguyen, P., Behm, F. G., Woodland, D. L., Doherty, P. C. and Blackman, M. A., Pathogenesis of an infectious mononucleosis-like disease induced by a murine γ-herpesvirus: role for a viral superantigen? J. Exp. Med. 1997. 185: 1641-1650.
16. Stevenson, P. G. and Doherty, P. C., Kinetic analysis of the host immune response to a murine γ-herpesvirus. J. Virol. 1998. 72: 943-949.
17. + T cells during an acute virus infection. Immunity 1998. 8: 167-175.
18. + T cells: a reevaluation of bystander activation during viral infection. Immunity 1998. 8: 177-187.
19. Sunil-Chandra, N. P., Efstathiou, S., Arno, J. and Nash, A. A., Virological and immunological features of mice infected with murine γ-herpesvirus 68. J. Gen. Virol. 1992. 73: 2347-2356.
20. + T cells. J. Exp. Med. 1996. 184: 863-871.
21. Raulet, D. H., MHC class I-deficient mice. Adv. Immunol. 1994. 55: 381-421.
22. Kieff, E., Epstein-Barr virus and its replication. In Fields, B. N., Knipe, D. M. and Harley, P. M. (Eds.) Virology. Lippincott-Raven, New York 1996, pp 2343-2396.
23. Steven, N. M., Leese, A. M., Annels, N. E., Lee, S. P. and Rickinson, A. B., Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory. J. Exp. Med. 1996. 184: 1801-1813.
24. Rickinson, A. B. and Moss, D. J., Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection. Annu. Rev. Immunol. 1997. 15: 405-431.
25. Steven, N. M., Annels, N. E., Kumar, A., Leese, A. M., Kurilla, M. G. and Rickinson, A. B., Immediate early and early lytic cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response. J. Exp. Med. 1997. 185: 1605-1617.
26. Nugent, C. T., McNally, J. M., Chervenak, P., Wolcott, R. M. and Jennings, S. R., Differences in the recognition of CTL epitopes during primary and secondary responses to herpex simplex virus infection in vivo. Cell. Immunol. 1995. 165: 55-64.
27. Koszinowski, U. H., Keil, G. M., Schwarz, H., Schikedanz, J. and Reddehase, M. J., A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolytic T lymphocytes. J. Exp. Med. 1987. 166: 289-294.
28. Borysiewicz, L. K., Hickling, J. K., Graham, S., Sinclair, J., Cranage, M. P., Smith, G. L. and Sissons, J. G., Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognising the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses. J. Exp. Med. 1988. 168: 919-931.
29. Tough, D. F., Borrow, P. and Sprent, J., Induction of bystander T cell proliferation by viruses and type 1 Interferon in vivo. Science 1996. 272: 1947-1950.
30. + T cells in acute infectious mononucleosis. Nature Med. 1996. 2: 906-911.
31. Kitamura, D. and Rajewsky, K., Targeted disruption of γ-chain transmembrane exon causes loss of heavy-chain allelic exclusion. Nature 1992. 356: 154-156.
32. + cytolytic T cells. Nature 1990. 344: 742-746.
33. Falk, K., Rötzschke, O., Stevanovic, S., Jung, G. and Rammensee, H.-G., Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991. 351: 290-296.
34. Altman, J. D., Moss, P. A. H., Goulder, P. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J. and Davis, M. M., Phenotypic analysis of antigen-specific T lymphocytes. Science 1996. 274: 94-96.
35. + T cells in primary and secondary influenza pneumonia. Immunity 1998. 8: 683-691.