Structure-function relationships in the 2-oxo acid dehydrogenase family: Substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins

Proteins: Structure, Function and Genetics

Volumn 71, Issue 2, 2008, Pages 874-890

  Bunik, Victoria I ^a   Degtyarev, Dmitry ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

2 oxo acid dehydrogenase; 2 oxo 4 hydroxyglutarate; 2 oxoadipate; DHTKD1; Glyoxylate; Lipoic acid; Neurodegeneration; OGDHL; Thiamine diphosphate

Indexed keywords

2 OXOACID DEHYDROGENASE; 2 OXOGLUTARIC ACID; ACETALDEHYDE; CALCIUM ION; CARBOXYLIC ACID DERIVATIVE; GLYOXYLIC ACID; OXOGLUTARATE DEHYDROGENASE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; GENOMICS; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

3-METHYL-2-OXOBUTANOATE DEHYDROGENASE (LIPOAMIDE); AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL NUCLEUS; HUMANS; KETOGLUTARATE DEHYDROGENASE COMPLEX; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PYRUVATE DEHYDROGENASE (LIPOAMIDE); SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THIAMINE PYROPHOSPHATE;

ANIMALIA;

EID: 41149139014     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21766     Document Type: Article

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