Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy

Journal of Biological Chemistry

Volumn 281, Issue 7, 2006, Pages 4364-4370

  Milne, Jacqueline L S ^a   Wu, Xiongwu ^b   Borgnia, Mario J ^a   Lengyel, Jeffrey S ^a,c   Brooks, Bernard R ^b   Shi, Dan ^a   Perham, Richard N ^c   Subramaniam, Sriram ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; DIMERS; ELECTRON MICROSCOPY; ENZYMES; SYNTHESIS (CHEMICAL);

DEHYDROGENASE; DITHIOLANE RING; MULTIENZYME COMPLEXES;

MOLECULAR STRUCTURE;

ACETYL COENZYME A; ACYLTRANSFERASE; DIHYDROLIPOAMIDE DEHYDROGENASE; DIHYDROLIPOYLACETYLTRANSFERASE; ENZYME; PYRUVATE DECARBOXYLASE; PYRUVATE DEHYDROGENASE; UNCLASSIFIED DRUG; PYRUVATE DEHYDROGENASE COMPLEX;

ARTICLE; BINDING SITE; CRYOELECTRON MICROSCOPY; ENZYME STRUCTURE; ENZYME SYNTHESIS; ESCHERICHIA COLI; PRIORITY JOURNAL; PROTEIN DOMAIN; REGENERATION; STOICHIOMETRY; THREE DIMENSIONAL IMAGING; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; ENZYMOLOGY; GEOBACILLUS STEAROTHERMOPHILUS; PROTEIN TERTIARY STRUCTURE;

GEOBACILLUS STEAROTHERMOPHILUS;

BACILLUS STEAROTHERMOPHILUS; BINDING SITES; CRYOELECTRON MICROSCOPY; DIMERIZATION; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 33645234725     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M504363200     Document Type: Article

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