GSK-3-specific inhibitor-supplemented hESC medium prevents the epithelial-mesenchymal transition process and the up-regulation of matrix metalloproteinases in hESCs cultured in feeder-free conditions

Molecular Human Reproduction

Volumn 14, Issue 3, 2008, Pages 169-179

  Ullmann, Urielle ^a   Gilles, C ^b   De Rycke, M ^a   Van de Velde, H ^a   Sermon, K ^a   Liebaers, I ^a  

^a UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Epithelial mesenchymal transition; Feeder free culture; GSK 3 inhibitor; Human embryonic stem cells; Matrix metalloproteinases

Indexed keywords

BETA CATENIN; CD147 ANTIGEN; GELATINASE A; GELATINASE B; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION;

CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; EPITHELIUM; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MESODERM; MICROSCOPY, ELECTRON, TRANSMISSION; OXIMES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

GASTROPODA;

EID: 40949148556     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gan001     Document Type: Article

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