메뉴 건너뛰기




Volumn 14, Issue 5, 2008, Pages 1502-1509

Evaluation of the antiangiogenic potential of AQ4N

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BIS[[2 (DIMETHYLAMINO N OXIDE)ETHYL]AMINO] 5,8 DIHYDROXYANTHRAQUINONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; DYNEIN ADENOSINE TRIPHOSPHATASE; FUMAGILLIN; MATRIGEL; PHALLOIDIN; TUBULIN; VIMENTIN;

EID: 40949106780     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-1262     Document Type: Article
Times cited : (13)

References (48)
  • 1
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 2
    • 0035254648 scopus 로고    scopus 로고
    • Angiogenesis: Regulators and clinical applications
    • Liekens S, De Clercq E, Neyts J. Angiogenesis: regulators and clinical applications. Biochem Pharmacol 2001;61:253-70.
    • (2001) Biochem Pharmacol , vol.61 , pp. 253-270
    • Liekens, S.1    De Clercq, E.2    Neyts, J.3
  • 3
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 5
    • 0037449461 scopus 로고    scopus 로고
    • Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential
    • Tan WF, Lin LP, Li MH, et al. Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential. Eur J Pharmacol 2003;459:255-62.
    • (2003) Eur J Pharmacol , vol.459 , pp. 255-262
    • Tan, W.F.1    Lin, L.P.2    Li, M.H.3
  • 6
    • 0020508740 scopus 로고
    • Shark cartilage contains inhibitors of tumor angiogenesis
    • Lee A, Langer R. Shark cartilage contains inhibitors of tumor angiogenesis. Science 1983;221:1185-7.
    • (1983) Science , vol.221 , pp. 1185-1187
    • Lee, A.1    Langer, R.2
  • 7
    • 0036179582 scopus 로고    scopus 로고
    • Snake venom disintegrin, saxatilin, inhibits platelet aggregation, human umbilical vein endothelial cell proliferation, and smooth muscle cell migration
    • Hong SY, Koh YS, Chung KH, Kim DS. Snake venom disintegrin, saxatilin, inhibits platelet aggregation, human umbilical vein endothelial cell proliferation, and smooth muscle cell migration. Thromb Res 2002;105:79-86.
    • (2002) Thromb Res , vol.105 , pp. 79-86
    • Hong, S.Y.1    Koh, Y.S.2    Chung, K.H.3    Kim, D.S.4
  • 8
    • 0035943444 scopus 로고    scopus 로고
    • Antiangiogenic potential of 10-hydroxycamptothecin
    • Xiao D, Tan W, Li M, Ding J. Antiangiogenic potential of 10-hydroxycamptothecin. Life Sci 2001;69:1619-28.
    • (2001) Life Sci , vol.69 , pp. 1619-1628
    • Xiao, D.1    Tan, W.2    Li, M.3    Ding, J.4
  • 9
    • 0037267664 scopus 로고    scopus 로고
    • Combining bioreductive drugs and radiation for the treatment of solid tumors
    • Stratford IJ, Williams KJ, Cowen RL, Jaffar M. Combining bioreductive drugs and radiation for the treatment of solid tumors. Semin Radiat Oncol 2003;13:42-52.
    • (2003) Semin Radiat Oncol , vol.13 , pp. 42-52
    • Stratford, I.J.1    Williams, K.J.2    Cowen, R.L.3    Jaffar, M.4
  • 11
    • 0345303905 scopus 로고    scopus 로고
    • Antiangiogenic hypoxic cytotoxin TX-402 inhibits hypoxia-inducible factor 1signaling pathway
    • Nagasawa H, Mikamo N, Nakajima Y, Matsumoto H, Uto Y, Hori H. Antiangiogenic hypoxic cytotoxin TX-402 inhibits hypoxia-inducible factor 1signaling pathway. Anticancer Res 2003;23:4427-34.
    • (2003) Anticancer Res , vol.23 , pp. 4427-4434
    • Nagasawa, H.1    Mikamo, N.2    Nakajima, Y.3    Matsumoto, H.4    Uto, Y.5    Hori, H.6
  • 12
    • 0027220811 scopus 로고
    • Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: A new class of bioreductive agent
    • Patterson LH. Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent. Cancer Metastasis Rev 1993;12:119-34.
    • (1993) Cancer Metastasis Rev , vol.12 , pp. 119-134
    • Patterson, L.H.1
  • 13
    • 0029054994 scopus 로고
    • AQ4N: An alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo
    • McKeown SR, Hejmadi MV, McIntyre IA, McAleer JJ, Patterson LH. AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo. Br J Cancer 1995;72:76-81.
    • (1995) Br J Cancer , vol.72 , pp. 76-81
    • McKeown, S.R.1    Hejmadi, M.V.2    McIntyre, I.A.3    McAleer, J.J.4    Patterson, L.H.5
  • 15
    • 0034024671 scopus 로고    scopus 로고
    • Enhancement of the anti-tumor effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine
    • Friery OP, Gallagher R, Murray MM, et al. Enhancement of the anti-tumor effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine. Br J Cancer 2000;82:1469-73.
    • (2000) Br J Cancer , vol.82 , pp. 1469-1473
    • Friery, O.P.1    Gallagher, R.2    Murray, M.M.3
  • 16
    • 0035902851 scopus 로고    scopus 로고
    • The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N
    • Gallagher R, Hughes CM, Murray MM, et al. The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N. Br J Cancer 2001;85:625-9.
    • (2001) Br J Cancer , vol.85 , pp. 625-629
    • Gallagher, R.1    Hughes, C.M.2    Murray, M.M.3
  • 17
    • 0029113394 scopus 로고
    • Characteristics of the inhibitory effect of mitoxantrone and pirarubicin on lung metastases of colon carcinoma 26
    • Iigo M, Shimamura M, Sagawa K, Tsuda H. Characteristics of the inhibitory effect of mitoxantrone and pirarubicin on lung metastases of colon carcinoma 26. Jpn J Cancer Res 1995;86:867-72.
    • (1995) Jpn J Cancer Res , vol.86 , pp. 867-872
    • Iigo, M.1    Shimamura, M.2    Sagawa, K.3    Tsuda, H.4
  • 18
    • 0036741259 scopus 로고    scopus 로고
    • Jeong SJ, Higuchi R, Miyamoto T, Ono M, Kuwano M, Mawatari SF. Bryoanthrathiophene, a new antiangiogenic constituent from the bryozoan Watersipora subtorquata (d'orbigny, 1852). J Nat Prod 2002;65:1344-5.
    • Jeong SJ, Higuchi R, Miyamoto T, Ono M, Kuwano M, Mawatari SF. Bryoanthrathiophene, a new antiangiogenic constituent from the bryozoan Watersipora subtorquata (d'orbigny, 1852). J Nat Prod 2002;65:1344-5.
  • 19
    • 4444273038 scopus 로고    scopus 로고
    • Inhibitory effects of emodin on angiogenesis
    • Wang XH, Wu SY, Zhen YS. Inhibitory effects of emodin on angiogenesis. Yao Xue Xue Bao 2004;39:254-8.
    • (2004) Yao Xue Xue Bao , vol.39 , pp. 254-258
    • Wang, X.H.1    Wu, S.Y.2    Zhen, Y.S.3
  • 20
    • 7444223476 scopus 로고    scopus 로고
    • Inhibition of endothelial cell functions by novel potential cancer chemopreventive agents
    • Bertl E, Becker H, Eicher T, et al. Inhibition of endothelial cell functions by novel potential cancer chemopreventive agents. Biochem Biophys Res Commun 2004;325:287-95.
    • (2004) Biochem Biophys Res Commun , vol.325 , pp. 287-295
    • Bertl, E.1    Becker, H.2    Eicher, T.3
  • 21
    • 0035182269 scopus 로고    scopus 로고
    • Structure and function of a vimentin-associated matrix adhesion in endothelial cells
    • Gonzales M, Weksler B, Tsuruta D, et al. Structure and function of a vimentin-associated matrix adhesion in endothelial cells. Mol Biol Cell 2001;12:85-100.
    • (2001) Mol Biol Cell , vol.12 , pp. 85-100
    • Gonzales, M.1    Weksler, B.2    Tsuruta, D.3
  • 22
    • 0033544876 scopus 로고    scopus 로고
    • Inhibition of endothelial cellmigration, intercellular communication, and vascular tube formation by thromboxane A(2)
    • Ashton AW, Yokota R, John G, et al. Inhibition of endothelial cellmigration, intercellular communication, and vascular tube formation by thromboxane A(2). J Biol Chem 1999;274:35562-70.
    • (1999) J Biol Chem , vol.274 , pp. 35562-35570
    • Ashton, A.W.1    Yokota, R.2    John, G.3
  • 23
    • 11244262363 scopus 로고    scopus 로고
    • Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration
    • Suchting S, Heal P, Tahtis K, Stewart LM, Bicknell R. Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration. FASEB J 2005;19:121-3.
    • (2005) FASEB J , vol.19 , pp. 121-123
    • Suchting, S.1    Heal, P.2    Tahtis, K.3    Stewart, L.M.4    Bicknell, R.5
  • 25
    • 0242637170 scopus 로고    scopus 로고
    • Targeting angiogenesis: A review of angiogenesis inhibitors in the treatment of lung cancer
    • Sridhar SS, Shepherd FA. Targeting angiogenesis: a review of angiogenesis inhibitors in the treatment of lung cancer. Lung Cancer 2003;42 Suppl 1:S81-91.
    • (2003) Lung Cancer , vol.42 , Issue.SUPPL. 1
    • Sridhar, S.S.1    Shepherd, F.A.2
  • 26
    • 0035865363 scopus 로고    scopus 로고
    • Redefining the target: Chemotherapeutics as antiangiogenics
    • Miller KD, Sweeney CJ, Sledge GW, Jr. Redefining the target: chemotherapeutics as antiangiogenics. J Clin Oncol 2001;19:1195-206.
    • (2001) J Clin Oncol , vol.19 , pp. 1195-1206
    • Miller, K.D.1    Sweeney, C.J.2    Sledge Jr., G.W.3
  • 27
    • 0034120430 scopus 로고    scopus 로고
    • TNP-470: An angiogenesis inhibitor in clinical development for cancer
    • Kruger EA, Figg WD. TNP-470: an angiogenesis inhibitor in clinical development for cancer. Expert Opin Investig Drugs 2000;9:1383-96.
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 1383-1396
    • Kruger, E.A.1    Figg, W.D.2
  • 28
    • 0036673761 scopus 로고    scopus 로고
    • In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cellmigration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton
    • Hayot C, Farinelle S, De Decker R, et al. In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cellmigration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton. Int J Oncol 2002;21:417-25.
    • (2002) Int J Oncol , vol.21 , pp. 417-425
    • Hayot, C.1    Farinelle, S.2    De Decker, R.3
  • 29
    • 0025204095 scopus 로고
    • Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth
    • Ingber D, Fujita T, Kishimoto S, et al. Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth. Nature 1990;348:555-7.
    • (1990) Nature , vol.348 , pp. 555-557
    • Ingber, D.1    Fujita, T.2    Kishimoto, S.3
  • 30
    • 0024434199 scopus 로고
    • Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro
    • Grant DS, Tashiro K, Segui-Real B, Yamada Y, Martin GR, Kleinman HK. Two different laminin domains mediate the differentiation of human endothelial cells into capillary-like structures in vitro. Cell 1989;58:933-43.
    • (1989) Cell , vol.58 , pp. 933-943
    • Grant, D.S.1    Tashiro, K.2    Segui-Real, B.3    Yamada, Y.4    Martin, G.R.5    Kleinman, H.K.6
  • 31
    • 0034652379 scopus 로고    scopus 로고
    • Hypoxia-dependent retinal toxicity of bioreductive anticancer prodrugs in mice
    • Lee AE, Wilson WR. Hypoxia-dependent retinal toxicity of bioreductive anticancer prodrugs in mice. Toxicol Appl Pharmacol 2000;163:50-9.
    • (2000) Toxicol Appl Pharmacol , vol.163 , pp. 50-59
    • Lee, A.E.1    Wilson, W.R.2
  • 32
    • 0025364195 scopus 로고
    • Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro
    • Nicosia RF, Ottinetti A. Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro. Lab Invest 1990;63:115-22.
    • (1990) Lab Invest , vol.63 , pp. 115-122
    • Nicosia, R.F.1    Ottinetti, A.2
  • 33
    • 0034607042 scopus 로고    scopus 로고
    • Endostatin inhibits microvessel formation in the ex vivo rat aortic ring angiogenesis assay
    • Kruger EA, Duray PH, Tsokos MG, et al. Endostatin inhibits microvessel formation in the ex vivo rat aortic ring angiogenesis assay. Biochem Biophys Res Commun 2000;268:183-91.
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 183-191
    • Kruger, E.A.1    Duray, P.H.2    Tsokos, M.G.3
  • 34
    • 0141842637 scopus 로고    scopus 로고
    • CEP-7055: A novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models
    • Ruggeri B, Singh J, Gingrich D, et al. CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. Cancer Res 2003;63:5978-91.
    • (2003) Cancer Res , vol.63 , pp. 5978-5991
    • Ruggeri, B.1    Singh, J.2    Gingrich, D.3
  • 35
    • 0035178210 scopus 로고    scopus 로고
    • Cell motility: Can rho GTPases and microtubules point the way?
    • Wittmann T, Waterman-Storer CM. Cell motility: can rho GTPases and microtubules point the way? J Cell Sci 2001;114:3795-803.
    • (2001) J Cell Sci , vol.114 , pp. 3795-3803
    • Wittmann, T.1    Waterman-Storer, C.M.2
  • 36
    • 0035204484 scopus 로고    scopus 로고
    • The social life of actin andmicrotubules: Interaction versus cooperation
    • Yarm F, Sagot I, Pellman D. The social life of actin andmicrotubules: interaction versus cooperation. Curr Opin Microbiol 2001;4:696-702.
    • (2001) Curr Opin Microbiol , vol.4 , pp. 696-702
    • Yarm, F.1    Sagot, I.2    Pellman, D.3
  • 37
    • 0032793783 scopus 로고    scopus 로고
    • Differential in vitro association of Vinca alkaloid-induced tubulin spiral filaments into aggregated spirals
    • Verdier-Pinard P, Gares M, Wright M. Differential in vitro association of Vinca alkaloid-induced tubulin spiral filaments into aggregated spirals. Biochem Pharmacol 1999;58:959-71.
    • (1999) Biochem Pharmacol , vol.58 , pp. 959-971
    • Verdier-Pinard, P.1    Gares, M.2    Wright, M.3
  • 38
    • 0032006059 scopus 로고    scopus 로고
    • Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
    • Jordan MA, Wilson L. Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr Opin Cell Biol 1998;10:123-30.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 123-130
    • Jordan, M.A.1    Wilson, L.2
  • 39
    • 0030063774 scopus 로고    scopus 로고
    • Modifications of vimentin filament architecture and vimentin-nuclear interactions by cholesterol oxides in 73/73 endothelial cells
    • Palladini G, Finardi G, Bellomo G. Modifications of vimentin filament architecture and vimentin-nuclear interactions by cholesterol oxides in 73/73 endothelial cells. Exp Cell Res 1996;223:83-90.
    • (1996) Exp Cell Res , vol.223 , pp. 83-90
    • Palladini, G.1    Finardi, G.2    Bellomo, G.3
  • 40
    • 12244257557 scopus 로고    scopus 로고
    • Vimentin intermediate filament reorganization by Cdc42: Involvement of PAK and p70 S6 kinase
    • Chan W, Kozma R, Yasui Y, et al. Vimentin intermediate filament reorganization by Cdc42: involvement of PAK and p70 S6 kinase. Eur J Cell Biol 2002;81:692-701.
    • (2002) Eur J Cell Biol , vol.81 , pp. 692-701
    • Chan, W.1    Kozma, R.2    Yasui, Y.3
  • 41
    • 0034647012 scopus 로고    scopus 로고
    • Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow
    • Helmke BP, Goldman RD, Davies PF. Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow. Circ Res 2000;86:745-52.
    • (2000) Circ Res , vol.86 , pp. 745-752
    • Helmke, B.P.1    Goldman, R.D.2    Davies, P.F.3
  • 42
    • 0025741269 scopus 로고
    • Pseudopodial activity at the active edge of migrating fibroblast is decreased after drug-induced microtubule depolymerization
    • Bershadsky AD, Vaisberg EA, Vasiliev JM. Pseudopodial activity at the active edge of migrating fibroblast is decreased after drug-induced microtubule depolymerization. Cell Motil Cytoskeleton 1991;19:152-8.
    • (1991) Cell Motil Cytoskeleton , vol.19 , pp. 152-158
    • Bershadsky, A.D.1    Vaisberg, E.A.2    Vasiliev, J.M.3
  • 43
    • 0033859762 scopus 로고    scopus 로고
    • Impaired wound healing in embryonic and adult mice lacking vimentin
    • Eckes B, Colucci-Guyon E, Smola H, et al. Impaired wound healing in embryonic and adult mice lacking vimentin. J Cell Sci 2000;113:2455-62.
    • (2000) J Cell Sci , vol.113 , pp. 2455-2462
    • Eckes, B.1    Colucci-Guyon, E.2    Smola, H.3
  • 44
    • 0035797905 scopus 로고    scopus 로고
    • Cdc42, dynein, and dynactin regulate MTOC reorientation independent of rho-regulated microtubule stabilization
    • Palazzo AF, Joseph HL, Chen YJ, et al. Cdc42, dynein, and dynactin regulate MTOC reorientation independent of rho-regulated microtubule stabilization. Curr Biol 2001;11:1536-41.
    • (2001) Curr Biol , vol.11 , pp. 1536-1541
    • Palazzo, A.F.1    Joseph, H.L.2    Chen, Y.J.3
  • 45
    • 0041519060 scopus 로고    scopus 로고
    • Centrosomal microtubule plus end tracking proteins and their role in dictyostelium cell dynamics
    • Hestermann A, Rehberg M, Graf R. Centrosomal microtubule plus end tracking proteins and their role in dictyostelium cell dynamics. J Muscle Res Cell Motil 2002;23:621-30.
    • (2002) J Muscle Res Cell Motil , vol.23 , pp. 621-630
    • Hestermann, A.1    Rehberg, M.2    Graf, R.3
  • 46
    • 0037182581 scopus 로고    scopus 로고
    • A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization
    • Helfand BT, Mikami A, Vallee RB, Goldman RD. A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. J Cell Biol 2002;157:795-806.
    • (2002) J Cell Biol , vol.157 , pp. 795-806
    • Helfand, B.T.1    Mikami, A.2    Vallee, R.B.3    Goldman, R.D.4
  • 47
    • 0030864069 scopus 로고    scopus 로고
    • Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: Implications for the generation of motile force
    • Cramer LP, Siebert M, Mitchison TJ. Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: implications for the generation of motile force. J Cell Biol 1997;136:1287-305.
    • (1997) J Cell Biol , vol.136 , pp. 1287-1305
    • Cramer, L.P.1    Siebert, M.2    Mitchison, T.J.3
  • 48
    • 0038348755 scopus 로고    scopus 로고
    • Small-molecule inhibitors of actin dynamics and cell motility
    • Fenteany G, Zhu S. Small-molecule inhibitors of actin dynamics and cell motility. Curr Top Med Chem 2003;3:593-616.
    • (2003) Curr Top Med Chem , vol.3 , pp. 593-616
    • Fenteany, G.1    Zhu, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.