Antiangiogenic Hypoxic Cytotoxin TX-402 Inhibits Hypoxia-inducible Factor 1 Signaling Pathway

Anticancer Research

Volumn 23, Issue 6 A, 2003, Pages 4427-4434

  Nagasawa, Hideko ^a   Mikamo, Naoko ^a   Nakajima, Yoshimi ^a   Matsumoto, Hideki ^b   Uto, Yoshihiro ^a   Hori, Hitoshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

Author keywords

Angiogenesis inhibitor; Hypoxia; Hypoxia inducible factor 1 (HIF 1); Hypoxic cytotoxin; P53; TX 402; Vascular endothelial cell growth factors (VEGF)

Indexed keywords

CYTOTOXIN; GLUCOSE TRANSPORTER 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN P53; TIRAPAZAMINE; TX 402; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; CELL ASSAY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG EFFECT; DRUG POTENCY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HYPOXIC CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; WILD TYPE;

ANGIOGENESIS INHIBITORS; ANIMALS; CARCINOMA, NON-SMALL-CELL LUNG; CELL HYPOXIA; CELL LINE, TUMOR; CHICK EMBRYO; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG NEOPLASMS; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION; TRIAZINES;

EID: 0345303905     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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