-
1
-
-
0035895505
-
-
Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome [published correction appears in Science. 2001;292(5523):1838]. Science. 2001;291(5507):1304-1351.
-
Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome [published correction appears in Science. 2001;292(5523):1838]. Science. 2001;291(5507):1304-1351.
-
-
-
-
2
-
-
2042437650
-
-
Lander ES, Linton LM, Birren B, et al; International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome [published corrections appear in Nature. 2001;412(6846):565 and Nature. 2001;411(6838):720]. Nature. 2001;409(6822):860-922.
-
Lander ES, Linton LM, Birren B, et al; International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome [published corrections appear in Nature. 2001;412(6846):565 and Nature. 2001;411(6838):720]. Nature. 2001;409(6822):860-922.
-
-
-
-
3
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium
-
International HapMap Consortium. A haplotype map of the human genome. Nature. 2005;437(7063):1299-1320.
-
(2005)
Nature
, vol.437
, Issue.7063
, pp. 1299-1320
-
-
-
4
-
-
34547618083
-
Drinking from the fire hose: Statistical issues in genomewide association studies
-
Hunter DJ, Kraft P. Drinking from the fire hose: statistical issues in genomewide association studies. N Engl J Med. 2007;357(5):436-439.
-
(2007)
N Engl J Med
, vol.357
, Issue.5
, pp. 436-439
-
-
Hunter, D.J.1
Kraft, P.2
-
5
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet. 2006;38(3):320-323.
-
(2006)
Nat Genet
, vol.38
, Issue.3
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
-
6
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 2007;445(7130):881-885.
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
-
7
-
-
34249888775
-
Diabetes Genetics Initiative of Broad Institute of Harvard and MIT; Lund University; Novartis Institutes of BioMedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, et al; Diabetes Genetics Initiative of Broad Institute of Harvard and MIT; Lund University; Novartis Institutes of BioMedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 2007;316(5829):1331-1336.
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
-
8
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science. 2007;316(5829):1336-1341.
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
-
9
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science. 2007;316(5829):1341-1345.
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
-
10
-
-
0031595923
-
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, et al. A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet. 1998;20(3):284-287.
-
(1998)
Nat Genet
, vol.20
, Issue.3
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
-
11
-
-
0029995670
-
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
-
Saltiel AR, Olefsky JM. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 1996;45(12):1661-1669.
-
(1996)
Diabetes
, vol.45
, Issue.12
, pp. 1661-1669
-
-
Saltiel, A.R.1
Olefsky, J.M.2
-
12
-
-
36048954488
-
Zinc supplementation for the prevention of type 2 diabetes mellitus
-
CD005525
-
Beletate V, El Dib RP, Atallah AN. Zinc supplementation for the prevention of type 2 diabetes mellitus. Cochrane Database Syst Rev. 2007;(1):CD005525.
-
Cochrane Database Syst Rev
, vol.2007
, Issue.1
-
-
Beletate, V.1
El Dib, R.P.2
Atallah, A.N.3
-
13
-
-
34047272692
-
-
Coon KD, Myers AJ, Craig DW, et al. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry. 2007;68(4):613-618.
-
Coon KD, Myers AJ, Craig DW, et al. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry. 2007;68(4):613-618.
-
-
-
-
14
-
-
34147181052
-
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500 288 single-nucleotide polymorphisms
-
Melquist S, Craig DW, Huentelman MJ, et al. Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500 288 single-nucleotide polymorphisms. Am J Hum Genet. 2007;80(4):769-778.
-
(2007)
Am J Hum Genet
, vol.80
, Issue.4
, pp. 769-778
-
-
Melquist, S.1
Craig, D.W.2
Huentelman, M.J.3
-
15
-
-
34249745769
-
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
-
Reiman EM, Webster JA, Myers AJ, et al. GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron. 2007;54(5):713-720.
-
(2007)
Neuron
, vol.54
, Issue.5
, pp. 713-720
-
-
Reiman, E.M.1
Webster, J.A.2
Myers, A.J.3
-
16
-
-
34548083742
-
Whole-genome analysis of sporadic amyotrophic lateral sclerosis [published online ahead of print August 1, 2007]
-
Dunckley T, Huentelman MJ, Craig DW, et al. Whole-genome analysis of sporadic amyotrophic lateral sclerosis [published online ahead of print August 1, 2007]. N Engl J Med. 2007;357(8):775-788.
-
(2007)
N Engl J Med
, vol.357
, Issue.8
, pp. 775-788
-
-
Dunckley, T.1
Huentelman, M.J.2
Craig, D.W.3
-
17
-
-
33847622526
-
Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: First stage analysis and public release of data
-
Schymick JC, Scholz SW, Fung HC, et al. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol. 2007;6(4):322-328.
-
(2007)
Lancet Neurol
, vol.6
, Issue.4
, pp. 322-328
-
-
Schymick, J.C.1
Scholz, S.W.2
Fung, H.C.3
-
18
-
-
33749667345
-
Genome-wide genotyping in Parkinson's disease and neurologically normal controls: First stage analysis and public release of data
-
Fung HC, Scholz S, Matarin M, et al. Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol. 2006;5(11):911-916.
-
(2006)
Lancet Neurol
, vol.5
, Issue.11
, pp. 911-916
-
-
Fung, H.C.1
Scholz, S.2
Matarin, M.3
-
19
-
-
34047274599
-
A genome-wide genotyping study in patients with ischaemic stroke: Initial analysis and data release
-
Matarín M, Brown WM, Scholz S, et al. A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Lancet Neurol. 2007;6(5):414-420.
-
(2007)
Lancet Neurol
, vol.6
, Issue.5
, pp. 414-420
-
-
Matarín, M.1
Brown, W.M.2
Scholz, S.3
-
20
-
-
33846531959
-
Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals
-
Simon-Sanchez J, Scholz S, Fung HC, et al. Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals. Hum Mol Genet. 2007;16(1):1-14.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.1
, pp. 1-14
-
-
Simon-Sanchez, J.1
Scholz, S.2
Fung, H.C.3
-
21
-
-
40849107398
-
-
Simon-Sanchez J, Scholz S, Del Mar Matarin M, et al. Genomewide SNP assay reveals mutations underlying Parkinson disease [published online ahead of print November 9, 2007]. Hum Mutat. 2007;(2).
-
Simon-Sanchez J, Scholz S, Del Mar Matarin M, et al. Genomewide SNP assay reveals mutations underlying Parkinson disease [published online ahead of print November 9, 2007]. Hum Mutat. 2007;(2).
-
-
-
-
22
-
-
85099526095
-
DYT16, a novel young-onset dystonia-parkinsonism disorder: Identification of a segregating mutation in the stress response protein prkra
-
In press
-
Camargos S, Scholz S, Simon-Sanchez J, et al. DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress response protein prkra. Lancet Neurol. In press.
-
Lancet Neurol
-
-
Camargos, S.1
Scholz, S.2
Simon-Sanchez, J.3
-
23
-
-
29444457877
-
International HapMap Consortium. Common deletion polymorphisms in the human genome
-
McCarroll SA, Hadnott TN, Perry GH, et al; International HapMap Consortium. Common deletion polymorphisms in the human genome. Nat Genet. 2006;38(1):86-92.
-
(2006)
Nat Genet
, vol.38
, Issue.1
, pp. 86-92
-
-
McCarroll, S.A.1
Hadnott, T.N.2
Perry, G.H.3
-
24
-
-
34347337686
-
Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans
-
doi:10.1371/journal.pgen.0030108
-
van de Leemput J, Chandran J, Knight MA, et al. Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS Genet. 2007;3(6):e108. doi:10.1371/journal.pgen.0030108.
-
(2007)
PLoS Genet
, vol.3
, Issue.6
-
-
van de Leemput, J.1
Chandran, J.2
Knight, M.A.3
-
25
-
-
33947220222
-
Structural variation in the human genome
-
Lupski JR. Structural variation in the human genome. N Engl J Med. 2007;356(11):1169-1171.
-
(2007)
N Engl J Med
, vol.356
, Issue.11
, pp. 1169-1171
-
-
Lupski, J.R.1
-
26
-
-
33847178181
-
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
-
Myers AJ, Pittman AM, Zhao AS, et al. The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts. Neurobiol Dis. 2007;25(3):561-570.
-
(2007)
Neurobiol Dis
, vol.25
, Issue.3
, pp. 561-570
-
-
Myers, A.J.1
Pittman, A.M.2
Zhao, A.S.3
-
27
-
-
3843056691
-
Multiple rare alleles contribute to low plasma levels of HDL cholesterol
-
Cohen JC, Kiss RS, Pertsemlidis A, Marcel YL, McPherson R, Hobbs HH. Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science. 2004;305(5685):869-872.
-
(2004)
Science
, vol.305
, Issue.5685
, pp. 869-872
-
-
Cohen, J.C.1
Kiss, R.S.2
Pertsemlidis, A.3
Marcel, Y.L.4
McPherson, R.5
Hobbs, H.H.6
-
28
-
-
34249949113
-
-
Kauwe JS, Jacquart S, Chakraverty S, et al. Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation. Ann Neurol. 2007;61(5):446-453.
-
Kauwe JS, Jacquart S, Chakraverty S, et al. Extreme cerebrospinal fluid amyloid beta levels identify family with late-onset Alzheimer's disease presenilin 1 mutation. Ann Neurol. 2007;61(5):446-453.
-
-
-
|