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Volumn 28, Issue 10, 2008, Pages 2495-2505

Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons

Author keywords

5 HT; Carbon dioxide; Chemoreception; Respiratory control; Temperature; Thermogenesis

Indexed keywords

CARBON DIOXIDE;

EID: 40449113428     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4729-07.2008     Document Type: Article
Times cited : (279)

References (79)
  • 1
    • 0037347924 scopus 로고    scopus 로고
    • Serotonin depletion increases respiratory variability in freely moving rats: Implications for panic disorder
    • Annerbrink K, Olsson M, Melchior LK, Hedner J, Eriksson E (2003) Serotonin depletion increases respiratory variability in freely moving rats: implications for panic disorder. Int J Neuropsychopharmacol 6:51-56.
    • (2003) Int J Neuropsychopharmacol , vol.6 , pp. 51-56
    • Annerbrink, K.1    Olsson, M.2    Melchior, L.K.3    Hedner, J.4    Eriksson, E.5
  • 2
    • 0037101635 scopus 로고    scopus 로고
    • Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis
    • Baker-Herman TL, Mitchell GS (2002) Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis. J Neurosci 22:6239-6246.
    • (2002) J Neurosci , vol.22 , pp. 6239-6246
    • Baker-Herman, T.L.1    Mitchell, G.S.2
  • 4
    • 0034456038 scopus 로고    scopus 로고
    • Role of the preoptic-anterior hypothalamus in thermoregulation and fever
    • Boulant JA (2000) Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clin Infect Dis 31 [Suppl 5]:S157-S161.
    • (2000) Clin Infect Dis , vol.31 , Issue.SUPPL. 5
    • Boulant, J.A.1
  • 5
    • 33646374657 scopus 로고    scopus 로고
    • Neuronal basis of Hammel's model for set-point thermoregulation
    • Boulant JA (2006) Neuronal basis of Hammel's model for set-point thermoregulation. J Appl Physiol 100:1347-1354.
    • (2006) J Appl Physiol , vol.100 , pp. 1347-1354
    • Boulant, J.A.1
  • 6
    • 0016167231 scopus 로고
    • The effect of spinal and skin temperatures on the firing rate and thermosensitivity of preoptic neurones
    • Boulant JA, Hardy JD (1974) The effect of spinal and skin temperatures on the firing rate and thermosensitivity of preoptic neurones. J Physiol (Lond) 240:639-660.
    • (1974) J Physiol (Lond) , vol.240 , pp. 639-660
    • Boulant, J.A.1    Hardy, J.D.2
  • 8
    • 0037414623 scopus 로고    scopus 로고
    • Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure
    • Cano G, Passerin AM, Schiltz JC, Card JP, Morrison SF, Sved AF (2003) Anatomical substrates for the central control of sympathetic outflow to interscapular adipose tissue during cold exposure. J Comp Neurol 460:303-326.
    • (2003) J Comp Neurol , vol.460 , pp. 303-326
    • Cano, G.1    Passerin, A.M.2    Schiltz, J.C.3    Card, J.P.4    Morrison, S.F.5    Sved, A.F.6
  • 9
    • 40449136664 scopus 로고    scopus 로고
    • Cooper KE, Veale WL (1986) Effects of temperature on breathing. In: Handbook of physiology, Sec 3, The respiratory system, II, Control of breathing (Cherniack NS, Widdicombe JG, eds), pp 691-702. Bethesda, MD: American Physiological Society.
    • Cooper KE, Veale WL (1986) Effects of temperature on breathing. In: Handbook of physiology, Sec 3, The respiratory system, Vol II, Control of breathing (Cherniack NS, Widdicombe JG, eds), pp 691-702. Bethesda, MD: American Physiological Society.
  • 10
    • 28844493032 scopus 로고    scopus 로고
    • Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins
    • Dailly E, Chenu F, Petit-Demouliere B, Bourin M (2006) Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins. J Neurosci Methods 150:111-115.
    • (2006) J Neurosci Methods , vol.150 , pp. 111-115
    • Dailly, E.1    Chenu, F.2    Petit-Demouliere, B.3    Bourin, M.4
  • 13
    • 0002834878 scopus 로고
    • A barometric method for measuring ventilation in newborn infants
    • Drorbaugh JE, Fenn WO (1955) A barometric method for measuring ventilation in newborn infants. Pediatrics 16:81-87.
    • (1955) Pediatrics , vol.16 , pp. 81-87
    • Drorbaugh, J.E.1    Fenn, W.O.2
  • 14
    • 0023932137 scopus 로고
    • Hypothermia and sudden infant death syndrome
    • Dunne KP, Matthews TG (1988) Hypothermia and sudden infant death syndrome. Arch Dis Child 63:438-440.
    • (1988) Arch Dis Child , vol.63 , pp. 438-440
    • Dunne, K.P.1    Matthews, T.G.2
  • 15
    • 34548828248 scopus 로고    scopus 로고
    • Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges
    • Erickson JT, Shafer G, Rossetti MD, Wilson CG, Deneris ES (2007) Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges. Respir Physiol Neurobiol 159:85-101.
    • (2007) Respir Physiol Neurobiol , vol.159 , pp. 85-101
    • Erickson, J.T.1    Shafer, G.2    Rossetti, M.D.3    Wilson, C.G.4    Deneris, E.S.5
  • 17
    • 0026583307 scopus 로고
    • Metabolism during normoxia, hyperoxia, and recovery in newborn rats
    • Frappell PB, Dotta A, Mortola JP (1992) Metabolism during normoxia, hyperoxia, and recovery in newborn rats. Can J Physiol Pharmacol 70:408-411.
    • (1992) Can J Physiol Pharmacol , vol.70 , pp. 408-411
    • Frappell, P.B.1    Dotta, A.2    Mortola, J.P.3
  • 18
    • 15244344433 scopus 로고    scopus 로고
    • Spinal synaptic enhancement with acute intermittent hypoxia improves respiratory function after chronic cervical spinal cord injury
    • Golder FJ, Mitchell GS (2005) Spinal synaptic enhancement with acute intermittent hypoxia improves respiratory function after chronic cervical spinal cord injury. J Neurosci 25:2925-2932.
    • (2005) J Neurosci , vol.25 , pp. 2925-2932
    • Golder, F.J.1    Mitchell, G.S.2
  • 19
    • 0021794102 scopus 로고
    • Relationship between autonomic and behavioral thermoregulation in the mouse
    • Gordon CJ (1985) Relationship between autonomic and behavioral thermoregulation in the mouse. Physiol Behav 34:687-690.
    • (1985) Physiol Behav , vol.34 , pp. 687-690
    • Gordon, C.J.1
  • 20
    • 0029924012 scopus 로고    scopus 로고
    • Cellular mechanisms for neuronal thermosensitivity in the rat hypothalamus
    • Griffin JD, Kaple ML, Chow AR, Boulant JA (1996) Cellular mechanisms for neuronal thermosensitivity in the rat hypothalamus. J Physiol (Lond) 492:231-242.
    • (1996) J Physiol (Lond) , vol.492 , pp. 231-242
    • Griffin, J.D.1    Kaple, M.L.2    Chow, A.R.3    Boulant, J.A.4
  • 21
    • 18844424364 scopus 로고    scopus 로고
    • Retrotrapezoid nucleus: A litmus test for the identification of central chemoreceptors
    • Guyenet PG, Stornetta RL, Bayliss DA, Mulkey DK (2005) Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors. Exp Physiol 90:247-253.
    • (2005) Exp Physiol , vol.90 , pp. 247-253
    • Guyenet, P.G.1    Stornetta, R.L.2    Bayliss, D.A.3    Mulkey, D.K.4
  • 23
    • 0344541954 scopus 로고    scopus 로고
    • Ventilatory and metabolic responses to cold and hypoxia in conscious rats with discrete hypothalamic lesions
    • Hinrichsen CF, Maskrey M, Mortola JP (1998) Ventilatory and metabolic responses to cold and hypoxia in conscious rats with discrete hypothalamic lesions. Respir Physiol 111:247-256.
    • (1998) Respir Physiol , vol.111 , pp. 247-256
    • Hinrichsen, C.F.1    Maskrey, M.2    Mortola, J.P.3
  • 24
    • 9244258595 scopus 로고    scopus 로고
    • Effects on breathing of focal acidosis at multiple medullary raphe sites in awake goats
    • Hodges MR, Martino P, Davis S, Opansky C, Pan LG, Forster HV (2004a) Effects on breathing of focal acidosis at multiple medullary raphe sites in awake goats. J Appl Physiol 97:2303-2309.
    • (2004) J Appl Physiol , vol.97 , pp. 2303-2309
    • Hodges, M.R.1    Martino, P.2    Davis, S.3    Opansky, C.4    Pan, L.G.5    Forster, H.V.6
  • 27
    • 0019403679 scopus 로고
    • Diminished hypoxic ventilatory responses in near-miss sudden infant death syndrome
    • Hunt CE, McCulloch K, Brouillette RT (1981) Diminished hypoxic ventilatory responses in near-miss sudden infant death syndrome. J Appl Physiol 50:1313-1317.
    • (1981) J Appl Physiol , vol.50 , pp. 1313-1317
    • Hunt, C.E.1    McCulloch, K.2    Brouillette, R.T.3
  • 28
    • 0024160418 scopus 로고
    • Temperature-related release of serotonin from unrestrained rats' pre-optic area perfused with ethanol
    • Huttunen P, Lapinlampi T, Myers RD (1988) Temperature-related release of serotonin from unrestrained rats' pre-optic area perfused with ethanol. Alcohol 5:189-193.
    • (1988) Alcohol , vol.5 , pp. 189-193
    • Huttunen, P.1    Lapinlampi, T.2    Myers, R.D.3
  • 30
    • 22344433287 scopus 로고    scopus 로고
    • Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats
    • Johnson PL, Hollis JH, Moratalla R, Lightman SL, Lowry CA (2005) Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats. J Psychopharmacol 19:327-341.
    • (2005) J Psychopharmacol , vol.19 , pp. 327-341
    • Johnson, P.L.1    Hollis, J.H.2    Moratalla, R.3    Lightman, S.L.4    Lowry, C.A.5
  • 31
    • 0032841171 scopus 로고    scopus 로고
    • Sleep and serotonin: An unfinished story
    • Jouvet M (1999) Sleep and serotonin: an unfinished story. Neuropsychopharmacology 21:24S-27S.
    • (1999) Neuropsychopharmacology , vol.21
    • Jouvet, M.1
  • 32
    • 34547631039 scopus 로고    scopus 로고
    • Compensatory airway dilation and additive ventilatory augmentation mediated by dorsomedial medullary 5-hydroxytryptamine 2 receptor activity and hypercapnia
    • Kanamaru M, Homma I (2007) Compensatory airway dilation and additive ventilatory augmentation mediated by dorsomedial medullary 5-hydroxytryptamine 2 receptor activity and hypercapnia. Am J Physiol Regul Integr Comp Physiol 293:R854-R860.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Kanamaru, M.1    Homma, I.2
  • 33
    • 0013986153 scopus 로고
    • p-Chlorophenylalanine: A specific depletor of brain serotonin
    • Koe BK, Weissman A (1966) p-Chlorophenylalanine: a specific depletor of brain serotonin. J Pharmacol Exp Ther 154:499-516.
    • (1966) J Pharmacol Exp Ther , vol.154 , pp. 499-516
    • Koe, B.K.1    Weissman, A.2
  • 34
    • 0016765831 scopus 로고
    • Stimulus interaction in the responses of carotid body chemoreceptor single afferent fibers
    • Lahiri S, DeLaney RG (1975) Stimulus interaction in the responses of carotid body chemoreceptor single afferent fibers. Respir Physiol 24:249-266.
    • (1975) Respir Physiol , vol.24 , pp. 249-266
    • Lahiri, S.1    DeLaney, R.G.2
  • 35
    • 0022923919 scopus 로고
    • Serotoninergic and non-serotoninergic responses of phrenic motoneurones to raphe stimulation in the cat
    • Lalley PM (1986) Serotoninergic and non-serotoninergic responses of phrenic motoneurones to raphe stimulation in the cat. J Physiol (Lond) 380:373-385.
    • (1986) J Physiol (Lond) , vol.380 , pp. 373-385
    • Lalley, P.M.1
  • 36
    • 0026701881 scopus 로고
    • Ionic mechanisms mediating 5-hydroxytryptamine- and noradrenaline-evoked depolarization of adult rat facial motoneurones
    • Larkman PM, Kelly JS (1992) Ionic mechanisms mediating 5-hydroxytryptamine- and noradrenaline-evoked depolarization of adult rat facial motoneurones. J Physiol (Lond) 456:473-490.
    • (1992) J Physiol (Lond) , vol.456 , pp. 473-490
    • Larkman, P.M.1    Kelly, J.S.2
  • 37
    • 0028325754 scopus 로고
    • c-fos-like immunoreactivity in the cat's neuraxis following moderate hypoxia or hypercapnia
    • Larnicol N, Wallois F, Berquin P, Gros F, Rose D (1994) c-fos-like immunoreactivity in the cat's neuraxis following moderate hypoxia or hypercapnia. J Physiol (Paris) 88:81-88.
    • (1994) J Physiol (Paris) , vol.88 , pp. 81-88
    • Larnicol, N.1    Wallois, F.2    Berquin, P.3    Gros, F.4    Rose, D.5
  • 39
    • 33751313602 scopus 로고    scopus 로고
    • Serotonin potentiates sympathetic responses evoked by spinal NMDA
    • Madden CJ, Morrison SF (2006) Serotonin potentiates sympathetic responses evoked by spinal NMDA. J Physiol (Lond) 577:525-537.
    • (2006) J Physiol (Lond) , vol.577 , pp. 525-537
    • Madden, C.J.1    Morrison, S.F.2
  • 41
    • 0343092041 scopus 로고    scopus 로고
    • Single-unit responses of serotonergic medullary and pontine raphe neurons to environmental cooling in freely moving cats
    • Martin-Cora FJ, Fornal CA, Metzler CW, Jacobs BL (2000) Single-unit responses of serotonergic medullary and pontine raphe neurons to environmental cooling in freely moving cats. Neuroscience 98:301-309.
    • (2000) Neuroscience , vol.98 , pp. 301-309
    • Martin-Cora, F.J.1    Fornal, C.A.2    Metzler, C.W.3    Jacobs, B.L.4
  • 43
    • 1942455273 scopus 로고    scopus 로고
    • Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesis
    • Morrison SF (2004a) Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesis. Am J Physiol Regul Integr Comp Physiol 286:R832-R837.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Morrison, S.F.1
  • 44
    • 2342574895 scopus 로고    scopus 로고
    • Central pathways controlling brown adipose tissue thermogenesis
    • Morrison SF (2004b) Central pathways controlling brown adipose tissue thermogenesis. News Physiol Sci 19:67-74.
    • (2004) News Physiol Sci , vol.19 , pp. 67-74
    • Morrison, S.F.1
  • 45
    • 0032423056 scopus 로고    scopus 로고
    • On the barometric method for measurements of ventilation, and its use in small animals
    • Mortola JP, Frappell PB (1998) On the barometric method for measurements of ventilation, and its use in small animals. Can J Physiol Pharmacol 76:937-944.
    • (1998) Can J Physiol Pharmacol , vol.76 , pp. 937-944
    • Mortola, J.P.1    Frappell, P.B.2
  • 46
    • 0021227930 scopus 로고
    • Supersensitivity to the respiratory stimulatory effect of TRH in 5,7-dihydroxytryptamine-treated rats
    • Mueller RA, Towle AC, Breese GR (1984) Supersensitivity to the respiratory stimulatory effect of TRH in 5,7-dihydroxytryptamine-treated rats. Brain Res 298:370-373.
    • (1984) Brain Res , vol.298 , pp. 370-373
    • Mueller, R.A.1    Towle, A.C.2    Breese, G.R.3
  • 48
    • 38449118278 scopus 로고    scopus 로고
    • Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism
    • Mulkey DK, Rosin DL, West G, Takakura AC, Moreira TS, Bayliss DA, Guyenet PG (2007) Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. J Neurosci 27:14128-14138.
    • (2007) J Neurosci , vol.27 , pp. 14128-14138
    • Mulkey, D.K.1    Rosin, D.L.2    West, G.3    Takakura, A.C.4    Moreira, T.S.5    Bayliss, D.A.6    Guyenet, P.G.7
  • 49
    • 32544435087 scopus 로고    scopus 로고
    • Medullary raphe neurons facilitate brown adipose tissue activation
    • Nason Jr MW, Mason P (2006) Medullary raphe neurons facilitate brown adipose tissue activation. J Neurosci 26:1190-1198.
    • (2006) J Neurosci , vol.26 , pp. 1190-1198
    • Nason Jr, M.W.1    Mason, P.2
  • 50
    • 0035185242 scopus 로고    scopus 로고
    • Central chemosensitivity, sleep, and wakefulness
    • Nattie EE (2001) Central chemosensitivity, sleep, and wakefulness. Respir Physiol 129:257-268.
    • (2001) Respir Physiol , vol.129 , pp. 257-268
    • Nattie, E.E.1
  • 51
    • 1942485936 scopus 로고    scopus 로고
    • Medullary serotonergic neurones and adjacent neurones that express neurokinin-1 receptors are both involved in chemoreception in vivo
    • Nattie EE, Li A, Richerson G, Lappi DA (2004) Medullary serotonergic neurones and adjacent neurones that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol (Lond) 556:235-253.
    • (2004) J Physiol (Lond) , vol.556 , pp. 235-253
    • Nattie, E.E.1    Li, A.2    Richerson, G.3    Lappi, D.A.4
  • 52
    • 0018775850 scopus 로고
    • Serotonin and the control of ventilation in awake rats
    • Olson Jr EB, Dempsey JA, McCrimmon DR (1979) Serotonin and the control of ventilation in awake rats. J Clin Invest 64:689-693.
    • (1979) J Clin Invest , vol.64 , pp. 689-693
    • Olson Jr, E.B.1    Dempsey, J.A.2    McCrimmon, D.R.3
  • 53
    • 0142062038 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine 1A receptors inhibit cold-induced sympathetically mediated cutaneous vasoconstriction in rabbits
    • Ootsuka Y, Blessing WW (2003) 5-Hydroxytryptamine 1A receptors inhibit cold-induced sympathetically mediated cutaneous vasoconstriction in rabbits. J Physiol (Lond) 552:303-314.
    • (2003) J Physiol (Lond) , vol.552 , pp. 303-314
    • Ootsuka, Y.1    Blessing, W.W.2
  • 54
    • 33644938792 scopus 로고    scopus 로고
    • Activation of 5-HT1A receptors in rostral medullary raphe inhibits cutaneous vasoconstriction elicited by cold exposure in rabbits
    • Ootsuka Y, Blessing WW (2006) Activation of 5-HT1A receptors in rostral medullary raphe inhibits cutaneous vasoconstriction elicited by cold exposure in rabbits. Brain Res 1073-1074:252-261.
    • (2006) Brain Res , vol.1073-1074 , pp. 252-261
    • Ootsuka, Y.1    Blessing, W.W.2
  • 55
    • 11244254968 scopus 로고    scopus 로고
    • Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1
    • Oshio K, Watanabe H, Song Y, Verkman AS, Manley GT (2005) Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1. FASEB J 19:76-78.
    • (2005) FASEB J , vol.19 , pp. 76-78
    • Oshio, K.1    Watanabe, H.2    Song, Y.3    Verkman, A.S.4    Manley, G.T.5
  • 56
    • 34147160256 scopus 로고    scopus 로고
    • Role of persistent sodium current in mouse preBotzinger Complex neurons and respiratory rhythm generation
    • Pace RW, Mackay DD, Feldman JL, Del Negro CA (2007) Role of persistent sodium current in mouse preBotzinger Complex neurons and respiratory rhythm generation. J Physiol (Lond) 580:485-496.
    • (2007) J Physiol (Lond) , vol.580 , pp. 485-496
    • Pace, R.W.1    Mackay, D.D.2    Feldman, J.L.3    Del Negro, C.A.4
  • 59
    • 0037114964 scopus 로고    scopus 로고
    • Endogenous activation of serotonin-2A receptors is required for respiratory rhythm generation in vitro
    • Pena F, Ramirez JM (2002) Endogenous activation of serotonin-2A receptors is required for respiratory rhythm generation in vitro. J Neurosci 22:11055-11064.
    • (2002) J Neurosci , vol.22 , pp. 11055-11064
    • Pena, F.1    Ramirez, J.M.2
  • 61
    • 0026640369 scopus 로고
    • The effect of p-chloroamphetamine and p-chlorophenylalanine on the level of thyrotropin-releasing hormone and its receptors in some brain structures and lumbar spinal cord of the rat
    • Przegalinski E, Jaworska L, Golembiowska K (1992) The effect of p-chloroamphetamine and p-chlorophenylalanine on the level of thyrotropin-releasing hormone and its receptors in some brain structures and lumbar spinal cord of the rat. Neuropeptides 23:19-25.
    • (1992) Neuropeptides , vol.23 , pp. 19-25
    • Przegalinski, E.1    Jaworska, L.2    Golembiowska, K.3
  • 62
    • 8644248306 scopus 로고    scopus 로고
    • Cellular mechanisms involved in CO(2) and acid signaling in chemosensitive neurons
    • Putnam RW, Filosa JA, Ritucci NA (2004) Cellular mechanisms involved in CO(2) and acid signaling in chemosensitive neurons. Am J Physiol Cell Physiol 287:C1493-C1526.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Putnam, R.W.1    Filosa, J.A.2    Ritucci, N.A.3
  • 63
    • 0021239580 scopus 로고
    • Catecholamines and serotonin in the rat central nervous system after 6-OHDA, 5-7-DHT and p-CPA
    • Reader TA, Gauthier P (1984) Catecholamines and serotonin in the rat central nervous system after 6-OHDA, 5-7-DHT and p-CPA. J Neural Transm 59:207-227.
    • (1984) J Neural Transm , vol.59 , pp. 207-227
    • Reader, T.A.1    Gauthier, P.2
  • 65
    • 0028988336 scopus 로고
    • Response to CO2 of neurons in the rostral ventral medulla in vitro
    • Richerson GB (1995) Response to CO2 of neurons in the rostral ventral medulla in vitro. J Neurophysiol 73:933-944.
    • (1995) J Neurophysiol , vol.73 , pp. 933-944
    • Richerson, G.B.1
  • 66
    • 2642547405 scopus 로고    scopus 로고
    • Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis
    • Richerson GB (2004) Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 5:449-461.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 449-461
    • Richerson, G.B.1
  • 67
    • 0035185087 scopus 로고    scopus 로고
    • Chemosensitivity of serotonergic neurons in the rostral ventral medulla
    • Richerson GB, Wang W, Tiwari J, Bradley SR (2001) Chemosensitivity of serotonergic neurons in the rostral ventral medulla. Respir Physiol 129:175-189.
    • (2001) Respir Physiol , vol.129 , pp. 175-189
    • Richerson, G.B.1    Wang, W.2    Tiwari, J.3    Bradley, S.R.4
  • 70
    • 0017761004 scopus 로고
    • Abnormal regulation of ventilation in infants at risk for sudden-infant-death syndrome
    • Shannon DC, Kelly DH, O'Connell K (1977) Abnormal regulation of ventilation in infants at risk for sudden-infant-death syndrome. N Engl J Med 297:747-750.
    • (1977) N Engl J Med , vol.297 , pp. 747-750
    • Shannon, D.C.1    Kelly, D.H.2    O'Connell, K.3
  • 71
    • 22744440628 scopus 로고    scopus 로고
    • Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats
    • Taylor NC, Li A, Nattie EE (2005) Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats. J Physiol (Lond) 566:543-557.
    • (2005) J Physiol (Lond) , vol.566 , pp. 543-557
    • Taylor, N.C.1    Li, A.2    Nattie, E.E.3
  • 73
    • 0029051506 scopus 로고
    • Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats
    • Veasey SC, Fornal CA, Metzler CW, Jacobs BL (1995) Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats. J Neurosci 15:5346-5359.
    • (1995) J Neurosci , vol.15 , pp. 5346-5359
    • Veasey, S.C.1    Fornal, C.A.2    Metzler, C.W.3    Jacobs, B.L.4
  • 74
    • 0025368354 scopus 로고
    • Tryptophan hydroxylase inhibition increases preprotachykinin mRNA in developing and adult medullary raphe nuclei
    • Walker PD, Schotland S, Hart RP, Jonakait GM (1990) Tryptophan hydroxylase inhibition increases preprotachykinin mRNA in developing and adult medullary raphe nuclei. Brain Res Mol Brain Res 8:113-119.
    • (1990) Brain Res Mol Brain Res , vol.8 , pp. 113-119
    • Walker, P.D.1    Schotland, S.2    Hart, R.P.3    Jonakait, G.M.4
  • 77
    • 34147151295 scopus 로고    scopus 로고
    • Carbon dioxide and pH effects on temperature-sensitive and -insensitive hypothalamic neurons
    • Wright CL, Boulant JA (2007) Carbon dioxide and pH effects on temperature-sensitive and -insensitive hypothalamic neurons. J Appl Physiol 102:1357-1366.
    • (2007) J Appl Physiol , vol.102 , pp. 1357-1366
    • Wright, C.L.1    Boulant, J.A.2
  • 79
    • 33845423914 scopus 로고    scopus 로고
    • Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity
    • Zhao ZQ, Scott M, Chiechio S, Wang JS, Renner KJ, Gereau RW, Johnson RL, Deneris ES, Chen ZF (2006) Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci 26:12781-12788.
    • (2006) J Neurosci , vol.26 , pp. 12781-12788
    • Zhao, Z.Q.1    Scott, M.2    Chiechio, S.3    Wang, J.S.4    Renner, K.J.5    Gereau, R.W.6    Johnson, R.L.7    Deneris, E.S.8    Chen, Z.F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.