-
1
-
-
0034646779
-
Down-regulation of orexin gene expression by severe obesity in the rats: Studies in Zucker fatty and Zucker diabetic fatty rats and effects of rosiglitazone
-
Cai X.J., Lister C.A., Buckingham R.E., Pickavance L., Wilding J., Arch J.R.et al. Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and Zucker diabetic fatty rats and effects of rosiglitazone. Brain Res. Mol. Brain Res. 77:2000;131-137.
-
(2000)
Brain Res. Mol. Brain Res.
, vol.77
, pp. 131-137
-
-
Cai, X.J.1
Lister, C.A.2
Buckingham, R.E.3
Pickavance, L.4
Wilding, J.5
Arch, J.R.6
-
2
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H., Charlat O., Tartaglia L.A., Woolf E.A., Weng X., Ellis S.J.et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell. 84:1996;491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
-
3
-
-
0033588184
-
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
-
Chemelli R.M., Willie J.T., Sinton C.M., Elmquist J.K., Scammell T., Lee C.et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell. 98:1999;437-451.
-
(1999)
Cell
, vol.98
, pp. 437-451
-
-
Chemelli, R.M.1
Willie, J.T.2
Sinton, C.M.3
Elmquist, J.K.4
Scammell, T.5
Lee, C.6
-
4
-
-
0026072307
-
Food deprivation and hypothalamic neuropeptide gene expression: Effects of strain background and the diabetes mutation
-
Chua S.C. Jr., Brown A.W., Kim J., Hennessey K.L., Leibel R.L., Hirsch J. Food deprivation and hypothalamic neuropeptide gene expression: effects of strain background and the diabetes mutation. Brain Res. Mol. Brain Res. 11:1991;291-299.
-
(1991)
Brain Res. Mol. Brain Res.
, vol.11
, pp. 291-299
-
-
Chua S.C., Jr.1
Brown, A.W.2
Kim, J.3
Hennessey, K.L.4
Leibel, R.L.5
Hirsch, J.6
-
5
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor
-
Chua S.C. Jr., Chung W.K., Wu-Peng X.S., Zhang Y., Liu S.M., Tartaglia L.et al. Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor. Science. 271:1996;994-996.
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua S.C., Jr.1
Chung, W.K.2
Wu-Peng, X.S.3
Zhang, Y.4
Liu, S.M.5
Tartaglia, L.6
-
6
-
-
0031761827
-
Functional properties of leptin receptor isoforms containing the gln → pro extracellular domain mutation of the fatty rat
-
da Silva B.A., Bjorbaek C., Uotani S., Flier J.S. Functional properties of leptin receptor isoforms containing the gln → pro extracellular domain mutation of the fatty rat. Endocrinology. 139:1998;3681-3690.
-
(1998)
Endocrinology
, vol.139
, pp. 3681-3690
-
-
Da Silva, B.A.1
Bjorbaek, C.2
Uotani, S.3
Flier, J.S.4
-
7
-
-
0008390266
-
The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
-
de Lecea L., Kilduff T.S., Peyron C., Gao X., Foye P.E., Danielson P.E.et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. U.S.A. 95:1998;322-327.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 322-327
-
-
De Lecea, L.1
Kilduff, T.S.2
Peyron, C.3
Gao, X.4
Foye, P.E.5
Danielson, P.E.6
-
8
-
-
0029985448
-
The serotonergic agent fluoxetine reduces neuropeptide Y levels and neuropeptide Y secretion in the hypothalamus of lean and obese rats
-
Dryden S., Frankish H.M., Wang Q., Pickavance L., Williams G. The serotonergic agent fluoxetine reduces neuropeptide Y levels and neuropeptide Y secretion in the hypothalamus of lean and obese rats. Neuroscience. 72:1996;557-566.
-
(1996)
Neuroscience
, vol.72
, pp. 557-566
-
-
Dryden, S.1
Frankish, H.M.2
Wang, Q.3
Pickavance, L.4
Williams, G.5
-
9
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson J.C., Hollopeter G., Palmiter R.D. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science. 274:1996;1704-1707.
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
10
-
-
0033071540
-
Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity
-
Funahashi T., Nakamura T., Shimomura I., Maeda K., Kuriyama H., Takahashi M.et al. Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity. Intern. Med. 38:1999;202-206.
-
(1999)
Intern. Med.
, vol.38
, pp. 202-206
-
-
Funahashi, T.1
Nakamura, T.2
Shimomura, I.3
Maeda, K.4
Kuriyama, H.5
Takahashi, M.6
-
11
-
-
0029737514
-
Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction
-
Gautvik K.M., de Lecea L., Gautvik V.T., Danielson P.E., Tranque P., Dopazo A.et al. Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction. Proc. Natl. Acad. Sci. U.S.A. 93:1996;8733-8738.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 8733-8738
-
-
Gautvik, K.M.1
De Lecea, L.2
Gautvik, V.T.3
Danielson, P.E.4
Tranque, P.5
Dopazo, A.6
-
12
-
-
0034678677
-
ARC POMC mRNA and PVN α-MSH are lower in obese relative to lean Zucker rats
-
Kim E.M., O'Hare E., Grace M.K., Welch C.C., Billington C.J., Levine A.S. ARC POMC mRNA and PVN α-MSH are lower in obese relative to lean Zucker rats. Brain Res. 862:2000;11-16.
-
(2000)
Brain Res.
, vol.862
, pp. 11-16
-
-
Kim, E.M.1
O'Hare, E.2
Grace, M.K.3
Welch, C.C.4
Billington, C.J.5
Levine, A.S.6
-
13
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee G.H., Proenca R., Montez J.M., Carroll K.M., Darvishzadeh J.G., Lee J.I.et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature. 379:1996;632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
-
14
-
-
0033529520
-
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
-
Lin L., Faraco J., Li R., Kadotani H., Rogers W., Lin X.et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell. 98:1999;365-376.
-
(1999)
Cell
, vol.98
, pp. 365-376
-
-
Lin, L.1
Faraco, J.2
Li, R.3
Kadotani, H.4
Rogers, W.5
Lin, X.6
-
15
-
-
0030991606
-
Analysis of an expression profile of genes in the human adipose tissue
-
Maeda K., Okubo K., Shimomura I., Mizuno K., Matsuzawa Y., Matsubara K. Analysis of an expression profile of genes in the human adipose tissue. Gene. 190:1997;227-235.
-
(1997)
Gene
, vol.190
, pp. 227-235
-
-
Maeda, K.1
Okubo, K.2
Shimomura, I.3
Mizuno, K.4
Matsuzawa, Y.5
Matsubara, K.6
-
16
-
-
0025612094
-
Localization of insulin receptor mRNA in rat brain by in situ hybridization
-
Marks J.L., Porte D. Jr., Stahl W.L., Baskin D.G. Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology. 127:1990;3234-3236.
-
(1990)
Endocrinology
, vol.127
, pp. 3234-3236
-
-
Marks, J.L.1
Porte D., Jr.2
Stahl, W.L.3
Baskin, D.G.4
-
17
-
-
0032779351
-
Molecular mechanism of metabolic syndrome X: Contribution of adipocytokines adipocyte-derived bioactive substances
-
Matsuzawa Y., Funahashi T., Nakamura T. Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann. N.Y. Acad. Sci. 892:1999;146-154.
-
(1999)
Ann. N.Y. Acad. Sci.
, vol.892
, pp. 146-154
-
-
Matsuzawa, Y.1
Funahashi, T.2
Nakamura, T.3
-
18
-
-
0032857104
-
Characterization of orexin-A and orexin-B in the microdissected rat brain nuclei and their contents in two obese rat models
-
Mondal M.S., Nakazato M., Date Y., Murakami N., Hanada R., Sakata T.et al. Characterization of orexin-A and orexin-B in the microdissected rat brain nuclei and their contents in two obese rat models. Neurosci. Lett. 273:1999;45-48.
-
(1999)
Neurosci. Lett.
, vol.273
, pp. 45-48
-
-
Mondal, M.S.1
Nakazato, M.2
Date, Y.3
Murakami, N.4
Hanada, R.5
Sakata, T.6
-
19
-
-
0019445983
-
Insulin acting as a modulator of feeding through the hypothalamus
-
Oomura Y., Kita H. Insulin acting as a modulator of feeding through the hypothalamus. Diabetologia. 20(Suppl.):1981;290-298.
-
(1981)
Diabetologia
, vol.20
, Issue.SUPPL.
, pp. 290-298
-
-
Oomura, Y.1
Kita, H.2
-
20
-
-
0016191102
-
Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus
-
Oomura Y., Ooyama H., Sugimori M., Nakamura T., Yamada Y. Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus. Nature. 247:1974;284-286.
-
(1974)
Nature
, vol.247
, pp. 284-286
-
-
Oomura, Y.1
Ooyama, H.2
Sugimori, M.3
Nakamura, T.4
Yamada, Y.5
-
22
-
-
0031913829
-
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat
-
Pick A., Clark J., Kubstrup C., Levisetti M., Pugh W., Bonner-Weir S.et al. Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes. 47:1998;358-364.
-
(1998)
Diabetes
, vol.47
, pp. 358-364
-
-
Pick, A.1
Clark, J.2
Kubstrup, C.3
Levisetti, M.4
Pugh, W.5
Bonner-Weir, S.6
-
23
-
-
0032489093
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H.et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 92:1998;573-585.
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
-
24
-
-
0025072899
-
Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation
-
Sanacora G., Kershaw M., Finkelstein J.A., White J.D. Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation. Endocrinology. 127:1990;730-737.
-
(1990)
Endocrinology
, vol.127
, pp. 730-737
-
-
Sanacora, G.1
Kershaw, M.2
Finkelstein, J.A.3
White, J.D.4
-
25
-
-
0026710057
-
Inhibition of hypothalamic neuropeptide Y gene expression by insulin
-
Schwartz M.W., Sipols A.J., Marks J.L., Sanacora G., White J.D., Scheurink A.et al. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology. 130:1992;3608-3616.
-
(1992)
Endocrinology
, vol.130
, pp. 3608-3616
-
-
Schwartz, M.W.1
Sipols, A.J.2
Marks, J.L.3
Sanacora, G.4
White, J.D.5
Scheurink, A.6
-
26
-
-
0025808045
-
Insulin acts on the hypothalamic glucose-facilitated neurons to induce hyperglycemia and hyperinsulinemia in the rat
-
Shian L.R., Lin M.T. Insulin acts on the hypothalamic glucose-facilitated neurons to induce hyperglycemia and hyperinsulinemia in the rat. Experientia. 47:1991;942-944.
-
(1991)
Experientia
, vol.47
, pp. 942-944
-
-
Shian, L.R.1
Lin, M.T.2
-
27
-
-
0023102618
-
Gastric related properties of rat paraventricular neurons
-
Shiraishi T. Gastric related properties of rat paraventricular neurons. Brain Res. Bull. 18:1987;315-323.
-
(1987)
Brain Res. Bull.
, vol.18
, pp. 315-323
-
-
Shiraishi, T.1
-
28
-
-
0023102617
-
Central control of gastric acid secretion by extralateral hypothalamic nuclei
-
Shiraishi T., Simpson A. Central control of gastric acid secretion by extralateral hypothalamic nuclei. Brain Res. Bull. 18:1987;309-314.
-
(1987)
Brain Res. Bull.
, vol.18
, pp. 309-314
-
-
Shiraishi, T.1
Simpson, A.2
-
29
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M.et al. The hormone resistin links obesity to diabetes. Nature. 409:2001;307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
Brown, E.J.4
Banerjee, R.R.5
Wright, C.M.6
-
30
-
-
0032782975
-
Distribution and quantification of immunoreactive orexin A in rat tissues
-
Taheri S., Mahmoodi M., Opacka-Juffry J., Ghatei M.A., Bloom S.R. Distribution and quantification of immunoreactive orexin A in rat tissues. FEBS Lett. 457:1999;157-161.
-
(1999)
FEBS Lett.
, vol.457
, pp. 157-161
-
-
Taheri, S.1
Mahmoodi, M.2
Opacka-Juffry, J.3
Ghatei, M.A.4
Bloom, S.R.5
-
31
-
-
0032582716
-
Distribution of orexin receptor mRNA in the rat brain
-
Trivedi P., Yu H., MacNeil D.J., Van der Ploeg L.H., Guan X.M. Distribution of orexin receptor mRNA in the rat brain. FEBS Lett. 438:1998;71-75.
-
(1998)
FEBS Lett.
, vol.438
, pp. 71-75
-
-
Trivedi, P.1
Yu, H.2
MacNeil, D.J.3
Van der Ploeg, L.H.4
Guan, X.M.5
-
32
-
-
0027254553
-
Increases in neuropeptide Y content and gene expression in the hypothalamus of rats treated with dexamethasone are prevented by insulin
-
Wilding J.P., Gilbey S.G., Lambert P.D., Ghatei M.A., Bloom S.R. Increases in neuropeptide Y content and gene expression in the hypothalamus of rats treated with dexamethasone are prevented by insulin. Neuroendocrinology. 57:1993;581-587.
-
(1993)
Neuroendocrinology
, vol.57
, pp. 581-587
-
-
Wilding, J.P.1
Gilbey, S.G.2
Lambert, P.D.3
Ghatei, M.A.4
Bloom, S.R.5
-
33
-
-
0033582606
-
Down regulation of the prepro-orexin gene expression in genetically obese mice
-
Yamamoto Y., Ueta Y., Date Y., Nakazato M., Hara Y., Serino R.et al. Down regulation of the prepro-orexin gene expression in genetically obese mice. Brain Res. Mol. Brain Res. 65:1999;14-22.
-
(1999)
Brain Res. Mol. Brain Res.
, vol.65
, pp. 14-22
-
-
Yamamoto, Y.1
Ueta, Y.2
Date, Y.3
Nakazato, M.4
Hara, Y.5
Serino, R.6
-
34
-
-
0034065518
-
Effects of food restriction on the hypothalamic prepro-orexin gene expression in genetically obese mice
-
Yamamoto Y., Ueta Y., Serino R., Nomura M., Shibuya I., Yamashita H. Effects of food restriction on the hypothalamic prepro-orexin gene expression in genetically obese mice. Brain Res. Bull. 51:2000;515-521.
-
(2000)
Brain Res. Bull.
, vol.51
, pp. 515-521
-
-
Yamamoto, Y.1
Ueta, Y.2
Serino, R.3
Nomura, M.4
Shibuya, I.5
Yamashita, H.6
-
35
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature. 372:1994;425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
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