Cryopreserved rat, dog and monkey hepatocytes: Measurement of drug metabolozing enzymes in suspensions and cultures

Human and Experimental Toxicology

Volumn 23, Issue 6, 2004, Pages 307-316

  Hewitt, Nicola J ^a,c   Utesch, Dietmar ^b  

^a In Vitro Technologies Inc   (United States)

^b MERCK KGAA   (Germany)

^c In Vitro Technologies Inc   (Germany)

Author keywords

Cryopreserved; Dog; Hepatocytes; Metabolism; Monkey; Rat

Indexed keywords

4 NITROPHENOL; CYTOCHROME P450 2C; CYTOCHROME P450 2D; CYTOCHROME P450 3A; DEXTROMETHORPHAN; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE; MIDAZOLAM; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFOTRANSFERASE; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL METABOLISM; CELL SUSPENSION; CONTROLLED STUDY; CRYOPRESERVATION; DOG; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME SUBSTRATE; LIVER CELL; MEASUREMENT; METABOLIC RATE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ANIMALS; BIOTRANSFORMATION; CELLS, CULTURED; CRYOPRESERVATION; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; ENZYMES; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; MACACA FASCICULARIS; MALE; PHARMACEUTICAL PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY; SULFOTRANSFERASES;

CANIS FAMILIARIS;

EID: 4043117632     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327104ht453oa     Document Type: Article

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