Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver

Xenobiotica

Volumn 28, Issue 4, 1998, Pages 349-360

  Olinga, P ^a   Merema, M T ^a   Hof, I H ^a   De Jager, M H ^a   De Jong, K P ^b   Slooff, M J H ^b   Meijer, D K F ^a   Groothuis, G M M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; COLORECTAL CANCER; DRUG METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER; LIVER CELL; LIVER METABOLISM; LIVER METASTASIS; LIVER SLICE; LIVER TRANSPLANTATION; MACACA; MONKEY; NONHUMAN;

ANIMALS; COLD; COUMARINS; CRYOPRESERVATION; HEAT; HUMANS; ISCHEMIA; LIDOCAINE; LIVER; MACACA FASCICULARIS; ORGAN PRESERVATION; TESTOSTERONE;

EID: 0031968984     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982598239461     Document Type: Article

References (39)

1. BARGETZI, M., AOYAMA, T., GONZALEZ, F. and MEYER, U., 1989, Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4. Clinical Pharmacology and Therapeutics, 46, 521-527.
2. BERTHOU, F., RATANASAVANH, D., RICHE, C., PICART, D., VOIRIN, T. and GUILLOUZO, A., 1989, Comparison of caffeine metabolism by slices, microsomes and hepatocyte cultures from adult human liver. Xenobiotica, 19, 401-417
3. BROUWERS, M. A. M., PEETERS, P. M. J. G., DE JONG, K. P., HAAGSMA, E. B., KLOMPMAKER, I. J., BIJLEVELD, C. M. A., ZWAVELING, J. H. and SLOOFF, M. J. H., 1997, Surgical treatment of giant hemangiomas of the liver. British Journal of Surgery, 84, 314-316.
4. CARACENI, P., GASBARRINI, A., NUSSLER, A., DI-SILVIO, M., BARTOLI, F., BORLE, A. B. and VANTHIEL, D. H., 1994, Human hepatocytes are more resistant than rat hepatocytes to anoxia-reoxygenation injury. Hepatology, 20, 1247-1254.
5. DE KANTER, R. and KOSTER, H. J., 1995, Cryopreservation of rat and monkey liver slices. Alternatives to Laboratory Animals, 23, 653-665.
6. DE KANTER, R., OLINGA, P., KOSTER, H. J., DE JAGER, M. H., SLOOFF, M. J. H., MEIJER, D. K. F. and GROOTHUIS, G. M. M., 1997, A simple method for the cryopreservation of liver slices from man and other species. In Animal Alternatives Welfare and Ethics, edited by L. F. M. Van Zutphen and M. Balls (Amsterdam: Elsevier), pp. 851-856.
7. EKINS, S., MURRAY, G. I., BURKE, M. D., WILLIAMS, J. A., MARCHANT, N. C. and HAWKSWORTH, G. M., 1995, Quantitative differences in phase I and II metabolism between rat precision-cut liver slices and isolated hepatocytes. Drug Metabolism Disposition, 23, 1274-1279.
8. FISHER, R., NAU, H., GANDOLFI, A. J., PUTNAM, C. W. and BRENDEL, K., 1991a, Valproic acid hepatotoxicity in human liver slices. Drug and Chemical Toxicology, 14, 375-394.
9. FISHER, R. L., HASAL, S. L., SANUIK, J. T., SCOTT, K. S., GANDOLFI, A. J. and BRENDEL, K., 1993, Cold and cryopreservation of human liver and kidney slices. Cryobiology, 30, 250-261.
10. FISHER, R. L., PUTNAM, C. W., KOEP, L. J., SIPES, I. G., GANDOLFI, A. J. and BRENDEL, K., 1991b, Cryopreservation of pig and human liver slices. Cryobiology, 28, 131-142.
11. GROOTHUIS, G. M. M., SANDKER, G. W., PRUIM, J., WEERT, B., SLOOFF, M. J. H. and MEIJER, D. K. F., 1995, Comparison of human hepatocytes isolated from livers accepted or discarded for orthotopic transplantation. Toxicology in Vitro, 9, 951-958.
12. HUGO-WISSEMANN, D., ANUNDI, I., LAUCHART, W., VIEBAHN, R. and DE GROOT, H., 1991, Differences in glycolytic capacity and hypoxia tolerance between hepatoma cells and hepatocytes. Hepatology, 13, 297-303.
13. KALAYOGLU, M., SOLLINGER, H. W., STRATTA, R. J., D'ALESSANDRO, A. M., HOFFMANN, R. M., PIRSCH, J. D. and BELZER, F. O., 1988, Extended preservation of the liver for clinical transplantation. Lancet, i, 617-619.
14. LORETZ, L. J., Li, A. P., FLYE, M. W. and WILSON, A. G. E., 1989, Optimization of cryopreservation procedures for rat and human hepatocytes. Xenobiotica, 19, 489-498.
15. MARSH, D. C., VREUGDENHIL, P. K., MACK, V. E., BELZER, F. O. and SOUTHARD, J. H., 1993, Glycine protects hepatocytes from injury caused by anoxia, cold ischaemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress. Hepatology, 17, 91-98.
16. MENNES, W. C., VAN-HOLSTEIJN, C. W., TIMMERMAN, A., NOORDHOEK, J. and BLAAUBOER, B. J., 1991, Biotransformation of scoparone used to monitor changes in cytochrome P450 activities in primary hepatocyte cultures derived from rats, hamsters and monkeys. Biochemical Pharmacology, 41, 1203-1208.
17. OLINGA, P., MEIJER, D. K. F., SLOOFF, M. J. H. and GROOTHUIS, G. M. M., 1998a, Liver slices in in vitro pharmacotoxicology with special reference to the use of human liver tissue. Toxicology in Vitro, 12, 77-100.
18. OLINGA, P., MEREMA, M. T., HOF, I. H., DE JONG, K. P., SLOOFF, M. J. H., MEIJER, D. K. F. and GROOTHUIS, G. M. M., 1998b, Effect of human liver source on the functionality of isolated hepatocytes and liver slices. Drug Metabolism and Disposition, 26.
19. OLINGA, P., MEREMA, M. T., MEIJER, D. K. F., SLOOFF, M. J. H. and GROOTHUIS, G. M. M., 1993, Human liver slices express the same lidocaine biotransformation rate as isolated human hepatocytes. Alternatives to Laboratory Animals, 21, 466-468.
20. OLINGA, P., MEREMA, M. T., SANDKER, G, W., SLOOFF, M. J. H., MEIJER, D. K. F. and GROOTHUIS, G. M. M., 1995, Use of human liver slices and hepatocytes in transport and metabolism studies. In The World Congress on Alternatives and Animal use in the Life Sciences : Education, Research, Testing, edited by A. M. Goldberg and L. F. M. Van Zutphen (New York : Liebert), pp. 197-203.
21. OLINGA, P., MEREMA, M. T., SLOOFF, M. J. H., MEIJER, D. K. F. and GROOTHUIS, G. M. M., 1997, The influence of 48 hours of cold storage in University of Wisconsin organ preservation solution on metabolic capacity of rat hepatocytes. Journal of Hepatology, 27, 738-743.
22. OUDE ELFERINK, R. P. J., MEIJER, D. K. F., KUIPERS, F., JANSEN, P. L. M., GROEN, A. K. and GROOTHUIS, G. M. M., 1995, Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport. Biochimica et Biophysica Acta, 1241, 215-268.
23. PARRISH, A. R., GANDOLFI, A. J. and BRENDEL, K., 1995, Precision cut liver slices: applications in pharmacology and toxicology. Life Science, 57, 1887-1901.
24. RIJNTJES, P. J. M., MOSHAGE, H. J., VAN GEMERT, P. J. L., DE WAAL, R. and YAP, S. H., 1986, Cryopreservation of adult human hepatocytes. The influence of deep freezing storage on the viability, cell seeding, survival, tine structures and albumin synthesis primary cultures. Journal of Hepatology, 3, 7-18.
25. SANDKER, G. W., SLOOF, M. J. H. and GROOTHUIS, G. M. M., 1992, Drug transport, viability and morphology of isolated rat hepatocytes preserved for 24 hours in University of Wisconsin solution. Biochemical Pharmacology, 43, 1479-1485.
26. SANDKER, G. W., VOS, R. M. E., DELBRESSINE, L. P. C., SLOOFF, M. J. H., MEIJER, D. K. F. and GROOTHUIS, G. M. M., 1994a, Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: analysis of interspecies variability and comparison with metabolism in vivo. Xenobiotica, 24, 143-155.
27. SANDKER, G. W., WEERT, B., OLINGA, P., WOLTERS, H., SLOOFF, M. J. H., MEIJER, D. K. F. and GROOTHUIS, G. M. M., 1994b, Characterization of transport in isolated human hepatocytes. A study with the bile acid taurocholic acid, the uncharged ouabain and the organic cations vecuronium and rocuronium. Biochemical Pharmacology, 47, 2193-2200.
28. SANDKER, G. W., WEERT, B., SLOOFF, M. J. H. and GROOTHUIS, G. M. M., 1990, Preservation of isolated rat and human hepatocytes in UW solution. Transplantation Proceedings, 22, 2204-2205.
29. SKETT, P., 1994, Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/ metabolism-based toxicity testing-solutions? Toxicology in Vitro, 3, 491-504.
30. STEENSMA, A., BEAMAND, J. A., WALTERS, D. G., PRICE, R. J. and LAKE, B. G., 1994, Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices. Xenobiotica, 24, 893-907.
31. STEVENS, J. C., SHIPLEY, L. A., CASHMAN, J. R., VANDENBRANDEN, M. and WRIGHTON, S. A., 1993, Comparison of human and rhesus monkey in vitro phase I and phase II hepatic drug metabolism activities. Drug Metabolism and Disposition, 21, 753-760.
32. UTESCH, D., DIENER, B., MOLITOR, E., OESCH, F. and PLATT, K. L., 1992, Characterization of cryopreserved rat liver parenchymal cells by metabolism of diagnostic substrates and activities of related enzymes. Biochemical Pharmacology, 44, 309-315.
33. VAN 'T KLOOSTER, G. A. E., BLAAUBOER, B. J., NOORDHOEK, J. and VAN MIERT, A. S. J. P. A. M., 1993, Cytochrome P450 induction and metabolism of alkoxyresofurins, ethylmorphine and testosterone in cultured hepatocytes from goats, sheep and cattle. Biochemical Pharmacology, 46, 1781-1790.
34. VREUGDENHIL, P. K., MARSH, D. C., MACK, V. E., BELZER, F. O. and SOUTHARD, J. H., 1993, Effect of fasting on hepatocytes cold stored in University of Wisconsin solution for 24 hours. Transplantation, 56, 1454-1459.
35. WALSH, J. S., PATANELLA, J. E., HALM, K. A. and FACCHINE, K. L., 1995, An improved HPLC assay for the assessment of liver slice metabolic viability using 7-ethoxycoumarine. Drug Metabolism and Disposition, 23, 869-874.
36. WISHNIES, S. M., PARRISH, A. R., SIPES, I. G., GANDOLFI, A. J., PUTNAM, C. W., KRUMDIECK, C. L. and BRENDEL, K., 1991, Biotransformation activity in vitrified human liver slices. Cryobiology, 28, 216-226.
37. WRIGHTON, S. A., BRIAN, W. R., SARI, M. A., IWASAKI, M., GUENGERICH, F. P., RAUCY, J. L., MOLOWA, D. T. and VANDENBRANDEN, M., 1990, Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3). Molecular Pharmacology, 38, 207-213.
38. YAMAZAKI, H., INOUE, K., MIMURA, M., ODA, Y., GUENGERICH, F. P. and SHIMADA, T., 1996, 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes. Biochemical Pharmacology, 51, 313-319.
39. ZALESKI, J., RICHBURG, J. and KAUFFMAN, F. C., 1993, Preservation of the rate and profile of xenobiotic metabolism in rat hepatocytes stored in liquid nitrogen. Biochemical Pharmacology, 46, 111-116.