Understanding functional divergence in proteins by studying intragenomic homologues

Biochemistry

Volumn 47, Issue 8, 2008, Pages 2592-2600

  Spoonamore, James E ^a   Bandarian, Vahe ^b,c  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; ENZYME ACTIVITY; FUNCTIONAL GROUPS; REACTION KINETICS;

INTRAGENOMIC HOMOLOGUES; MULTISTEP TRANSFORMATIONS;

PROTEINS;

GUANOSINE TRIPHOSPHATE; METHIONINE; PYRIMIDINONE DERIVATIVE; TYROSINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENOME; CATALYSIS; GENETIC VARIABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STREPTOMYCES COELICOLOR;

BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CONSERVED SEQUENCE; GENOME, BACTERIAL; GTP CYCLOHYDROLASE; HYDROLYSIS; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID; STREPTOMYCES COELICOLOR; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); STREPTOMYCES COELICOLOR;

EID: 39749110672     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702263z     Document Type: Article

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