-
1
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 2001;411:599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
2
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
-
3
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin SE, Boneca IG, Viala J, et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem. 2003;278:8869-8872.
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
-
4
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe T, Chamaillard M, Ogura Y, et al. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J. 2004;23:1587-1597.
-
(2004)
EMBO J
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
-
5
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Abbott DW, Wilkins A, Asara JM, Cantley LC. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 2004;14:2217-27.
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Abbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
6
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003;278:5509-5512.
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
-
7
-
-
33745556685
-
Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation
-
Kramer M, Netea MG, de Jong DJ, Kullberg BJ, Adema GJ. Impaired dendritic cell function in Crohn's disease patients with NOD2 3020insC mutation. J Leukoc Biol. 2006;79:860-866.
-
(2006)
J Leukoc Biol
, vol.79
, pp. 860-866
-
-
Kramer, M.1
Netea, M.G.2
de Jong, D.J.3
Kullberg, B.J.4
Adema, G.J.5
-
8
-
-
20844454920
-
Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release
-
Netea MG, Ferwerda G, de Jong DJ, et al. Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release. J Immunol 2005;174:6518-6523.
-
(2005)
J Immunol
, vol.174
, pp. 6518-6523
-
-
Netea, M.G.1
Ferwerda, G.2
de Jong, D.J.3
-
9
-
-
27444444603
-
Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease
-
van Heel DA, Ghosh S, Hunt KA, et al. Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease. Gut. 2005;54:1553-1557.
-
(2005)
Gut
, vol.54
, pp. 1553-1557
-
-
van Heel, D.A.1
Ghosh, S.2
Hunt, K.A.3
-
11
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe T, Kitani A, Murray PJ, Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 2004;5:800-808.
-
(2004)
Nat Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
12
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
Maeda S, Hsu LC, Liu H, et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 2005;307:734-738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
-
13
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression
-
Wehkamp J, Harder J, Weichenthal M, et al. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut. 2004;53:1658-1664.
-
(2004)
Gut
, vol.53
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
-
14
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 2005;307:731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
-
15
-
-
23844495249
-
Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients
-
Braat H, Stokkers P, Hommes T, et al. Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients. J Mol Med. 2005;83:601-609.
-
(2005)
J Mol Med
, vol.83
, pp. 601-609
-
-
Braat, H.1
Stokkers, P.2
Hommes, T.3
-
16
-
-
0028289244
-
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
-
Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med. 1994;179:1109-1118.
-
(1994)
J Exp Med
, vol.179
, pp. 1109-1118
-
-
Sallusto, F.1
Lanzavecchia, A.2
-
17
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5:R80.
-
(2004)
Genome Biol
, vol.5
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
-
19
-
-
39649110427
-
-
Technical note. Rosetta Biosoftware. Re-ratio and Ratio Split Processing: Supplement User Information. Rosetta, Seattle, WA; 2003
-
Technical note. Rosetta Biosoftware. Re-ratio and Ratio Split Processing: Supplement User Information. Rosetta, Seattle, WA; 2003
-
-
-
-
20
-
-
39649113151
-
-
Stoughton R, Hongyue DH. Statistical Combining of Cell Expression Profiles. U.S. Pat. 6,351,712. February 26, 2002.
-
Stoughton R, Hongyue DH. Statistical Combining of Cell Expression Profiles. U.S. Pat. 6,351,712. February 26, 2002.
-
-
-
-
21
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B. 1995;57:289-300.
-
(1995)
J R Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
22
-
-
2942550697
-
GOTree Machine (GOTM): A web-based platform for interpreting sets of interesting genes using gene ontology hierarchies
-
Zhang B, Schmoyer D, Kirov S, et al. GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using gene ontology hierarchies. BMC Bioinformatics. 2004;5:16.
-
(2004)
BMC Bioinformatics
, vol.5
, pp. 16
-
-
Zhang, B.1
Schmoyer, D.2
Kirov, S.3
-
23
-
-
0004252445
-
-
4th ed. Upper Saddle River, NJ: Prentice Hall;
-
Zar JH. Biostatistical Analysis. 4th ed. Upper Saddle River, NJ: Prentice Hall; 1998.
-
(1998)
Biostatistical Analysis
-
-
Zar, J.H.1
-
24
-
-
3442899939
-
NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: Implications for Crohn's disease
-
Netea MG, Kullberg BJ, de Jong DJ, et al. NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease. Eur J Immunol. 2004;34:2052-2059.
-
(2004)
Eur J Immunol
, vol.34
, pp. 2052-2059
-
-
Netea, M.G.1
Kullberg, B.J.2
de Jong, D.J.3
-
25
-
-
21144468350
-
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease
-
van Heel DA, Ghosh S, Butler M, et al. Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease. Lancet. 2005;365:1794-1796.
-
(2005)
Lancet
, vol.365
, pp. 1794-1796
-
-
van Heel, D.A.1
Ghosh, S.2
Butler, M.3
-
26
-
-
0037308263
-
The genetics of inflammatory bowel disease
-
Bonen DK, Cho JH. The genetics of inflammatory bowel disease. Gastroenterology. 2003;124:521-536.
-
(2003)
Gastroenterology
, vol.124
, pp. 521-536
-
-
Bonen, D.K.1
Cho, J.H.2
-
27
-
-
18144369681
-
The CATERPILLER family: An ancient family of immune/apoptotic proteins
-
Ting JP, Williams KL. The CATERPILLER family: an ancient family of immune/apoptotic proteins. Clin Immunol. 2005;115:33-37.
-
(2005)
Clin Immunol
, vol.115
, pp. 33-37
-
-
Ting, J.P.1
Williams, K.L.2
-
28
-
-
0033532091
-
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB
-
Bertin J, Nir WJ, Fischer CM, et al. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB. J Biol Chem. 1999;274:12955-129558.
-
(1999)
J Biol Chem
, vol.274
, pp. 12955-129558
-
-
Bertin, J.1
Nir, W.J.2
Fischer, C.M.3
-
29
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB
-
Inohara N, Koseki T, del Peso L, et al. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J Biol Chem. 1999;274:14560-14567.
-
(1999)
J Biol Chem
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
Koseki, T.2
del Peso, L.3
-
30
-
-
22344448660
-
Characteristics of intestinal dendritic cells in inflammatory bowel diseases
-
Hart AL, Al Hassi HO, Rigby RJ, et al. Characteristics of intestinal dendritic cells in inflammatory bowel diseases. Gastroenterology. 2005;129:50-65.
-
(2005)
Gastroenterology
, vol.129
, pp. 50-65
-
-
Hart, A.L.1
Al Hassi, H.O.2
Rigby, R.J.3
-
31
-
-
0037255218
-
Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease
-
te Velde AA, van Kooyk Y, Braat H, et al. Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease. Eur J Immunol. 2003;33:143-51.
-
(2003)
Eur J Immunol
, vol.33
, pp. 143-151
-
-
te Velde, A.A.1
van Kooyk, Y.2
Braat, H.3
-
32
-
-
33644502594
-
Dendritic cell apoptosis in the maintenance of immune tolerance
-
Chen M, Wang YH, Wang Y, et al. Dendritic cell apoptosis in the maintenance of immune tolerance. Science. 2006;311:1160-1164.
-
(2006)
Science
, vol.311
, pp. 1160-1164
-
-
Chen, M.1
Wang, Y.H.2
Wang, Y.3
-
33
-
-
26044460479
-
NOD2 3020insC mutation and the pathogenesis of Crohn's disease: Impaired IL-1beta production points to a loss-of-function phenotype
-
Netea MG, Ferwerda G, de Jong DJ, et al. NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype. Neth J Med. 2005;63:305-308.
-
(2005)
Neth J Med
, vol.63
, pp. 305-308
-
-
Netea, M.G.1
Ferwerda, G.2
de Jong, D.J.3
-
34
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon F, Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 2005;26:447-454.
-
(2005)
Trends Immunol
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
35
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
Martinon F, Agostini L, Meylan E, et al. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol. 2004;14:1929-1934.
-
(2004)
Curr Biol
, vol.14
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
|