Acetaminophen: Antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant

Prostaglandins and Other Lipid Mediators

Volumn 85, Issue 3-4, 2008, Pages 89-99

  Li, Shuxin ^a   Dou, Wenkai ^a,b   Tang, Ying ^a   Goorha, Sarita ^a,b   Ballou, Leslie R ^a,b   Blatteis, Clark M ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antioxidants; Antipyretics; Body (core) temperature; Fever; Glutamate; Lipopolysaccharide; NSAIDs; Pghs 1 gene ablated mice; PGHS 1 splice variant retaining intron 1 (PGHS 1b); Prostaglandin (PG)E2; Prostaglandin H2 synthase (PGHS) 3 (COX 3)

Indexed keywords

ANTIPYRETIC AGENT; CYCLOOXYGENASE 3; LIPOPOLYSACCHARIDE; PARACETAMOL; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PYROGEN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CATALYSIS; CONTROLLED STUDY; CORE TEMPERATURE; ESCHERICHIA COLI; FEVER; HYPOTHERMIA; LIPID BRAIN LEVEL; MOUSE; NONHUMAN; PROSTAGLANDIN BLOOD LEVEL; TREATMENT RESPONSE; UPREGULATION;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CYCLOOXYGENASE 1; DINOPROSTONE; HANDLING (PSYCHOLOGY); HYPOTHERMIA, INDUCED; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 39649118185     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2007.10.007     Document Type: Article

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