HIV-1 protecting CCR5-Δ32 allele in medieval Poland

Infection, Genetics and Evolution

Volumn 8, Issue 2, 2008, Pages 146-151

  Zawicki, Przemysław ^a   Witas, Henryk W ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

AIDS; Ancient DNA (aDNA); Black death; C C chemokine receptor 5 (CCR5); CCR5 32; HIV

Indexed keywords

CHEMOKINE RECEPTOR CCR5; DNA;

ALLELE; ARCHEOLOGY; ARTICLE; DNA DETERMINATION; DNA ISOLATION; EUROPE; GENE FREQUENCY; GENE MAPPING; GENE MUTATION; HOMOZYGOSITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; NONHUMAN; PANDEMIC; POLAND; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ALLELES; BASE SEQUENCE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HISTORY, MEDIEVAL; HIV-1; HUMANS; IMMUNITY, NATURAL; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; POLAND; RECEPTORS, CCR5;

HUMAN IMMUNODEFICIENCY VIRUS 1; VARIOLA VIRUS;

EID: 39649095853     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2007.11.003     Document Type: Article

References (48)

1. Ansari-Lari M.A., Liu X.M., Metzker M.L., Rut A.R., and Gibbs R.A. The extent of genetic variation in the CCR5 gene. Nat. Genet. 16 (1997) 221-222
2. Balanovsky O., Pocheshkhova E., Pshenichnov A., Solovieva D., Kuznetsova M., Voronko O., Churnosov M., Tegako O., Atramentova L., Lavryashina M., Evseeva I., Borinska S., Boldyreva M., Dubova N., and Balanovska E. Is spatial distribution of the HIV-1-resistant CCR5Delta32 allele formed by ecological factors?. J. Physiol. Anthropol. Appl. Hum. Sci. 24 (2005) 375-382
3. Blanpain C., Libert F., Vassart G., and Parmentier M. CCR5 and HIV infection. Recept. Channels 8 (2002) 19-31
4. Carrington M., Kissner T., Gerrard B., Ivanov S., O'Brien S.J., and Dean M. Novel alleles of the chemokine-receptor gene CCR5. Am. J. Hum. Genet. 61 (1997) 1261-1267
5. Chen Z., Kwon D., Jin Z., Monard S., Telfer P., Jones M.S., Lu C.Y., Aguilar R.F., Ho D.D., and Marx P.A. Natural infection of a homozygous delta24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus. J. Exp. Med. 188 11 (1998) 2057-2065
6. Collins M.J., and Galley P. Towards an optimal method of archaeological collagen extraction; the influence of pH and grinding. Anc. Biomol. 2 (1998) 209-222
7. Dean M., Carrington M., Winkler C., Huttley G.A., Smith M.W., Allikmets R., Goedert J.J., Buchbinder S.P., Vittinghoff E., Gomperts E., Donfield S., Vlahov D., Kaslow R., Saah A., Rinaldo C., Detels R., and O'Brien S.J. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science 273 (1996) 1856-1862
8. Duncan C.J., and Scott S. What caused Black Death?. Postgrad. Med. J. 81 (2005) 315-320
9. Elvin S.J., Williamson E.D., Scott J.C., Smith J.N., Perez De Lema G., Chilla S., Clapham P., Pfeffer K., Schlondorff D., and Luckow B. Evolutionary genetics: ambiguous role of CCR5 in Y. pestis infection. Nature 430 (2004) 417
10. Floto R.A., MacAry P.A., Boname J.M., Mien T.S., Kampmann B., Hair J.R., Huey O.S., Houben E.N., Pieters J., Day C., Oehlmann W., Singh M., Smith K.G., and Lehner P.J. Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5. Science 314 (2006) 454-458
11. Galvani A.P., and Slatkin M. Evaluating plague and smallpox as historical selective pressures for the CCR5-Δ32 HIV-resistance allele. PNAS 100 (2003) 15276-15279
12. Galvani A.P., and Novembre J. The evolutionary history of the CCR5-Delta32 HIV-resistance mutation. Microbes Infect. 7 2 (2005) 302-309
13. Glass W.G., McDermott D.H., Lim J.K., Lekhong S., Yu S.F., Frank W.A., Pape J., Cheshier R.C., and Murphy P.M. CCR5 deficiency increases risk of symptomatic West Nile virus infection. J. Exp. Med. 203 (2006) 35-40
14. Hedrick P.W., and Verrelli B.C. "Ground truth" for selection on CCR5-Delta32. Trends Genet. 22 6 (2006) 293-296
15. Hummel S. Ancient DNA typing: methods, strategies, and applications (2003), Springer-Verlag, Berlin Heidelberg, Germany p. 236
16. Hummel S., Schmidt D., Kremeyer B., Herrmann B., and Oppermann M. Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons. Genes Immun. 6 (2005) 371-374
17. Husain S., Goila R., Shahi S., and Banerjea A. First report of a healthy Indian heterozygous for delta 32 mutant of HIV-1 co-receptor-CCR5 gene. Gene 207 2 (1998) 141-147
18. Jagodziński P.P., Lecybyl R., Ignacak M., Juszczyk J., and Trzeciak W.H. Distribution of 32 alelle of the CCR5 gene in the population of Poland. J. Hum. Genet. 45 (2000) 271-274
19. Khan I.A., Thomas S.Y., Moretto M.M., Lee F.S., Islam S.A., Combe C., Schwartzman J.D., and Luster A.D. CCR5 is essential for NK cell trafficking and host survival following Toxoplasmagondii infection. PLoS Pathog. 2 (2006) e49
20. Klitz W., Brautbar C., Schito A.M., Barcellos L.F., and Oksenberg J.R. Evolution of the CCR5 Delta32 mutation based on haplotype variation in Jewish and Northern European population samples. Hum. Immunol. 62 (2001) 530-538
21. Kremeyer B., Hummel S., and Herrmann B. Frequency analysis of the delta32ccr5 HIV resistance allele in a medieval plague mass grave. Anthropol. Anz. 63 (2005) 13-22
22. Kurashima K., Mukaida N., Fujimura M., Yasui M., Nakazumi Y., Matsuda T., and Matsushima K. Elevated chemokine levels in bronchoalveolar lavage fluid of tuberculosis patients. Am. J. Respir. Crit. Care. Med. 155 4 (1997) 1474-1477
23. Leboute A.P., de Carvalho M.W., and Simoes A.L. Absence of the deltaccr5 mutation in indigenous populations of the Brazilian Amazon. Hum. Genet. 105 (1999) 442-443
24. Libert F., Cochaux P., Beckman G., Samson M., Aksenova M., Cao A., Czeizel A., Claustres M., de la Rua C., Ferrari M., Ferrec C., Glover G., Grinde B., Guran S., Kucinskas V., Lavinha J., Mercier B., Ogur G., Peltonen L., Rosatelli C., Schwartz M., Spitsyn V., Timar L., Beckman L., Parmentier M., and Vassart G. The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in North Eastern Europe. Hum. Mol. Genet. 7 (1998) 399-406
25. Limborska S.A., Balanovsky O.P., Balanovskaya E.V., Slominsky P.A., Schadrina M.I., Livshits L.A., Kravchenko S.A., Pampuha V.M., Khusnutdinova E.K., and Spitsyn V.A. Analysis of CCR5Delta32 geographic distribution and its correlation with some climatic and geographic factors. Hum. Hered. 53 (2002) 49-54
26. Liu R., Paxton W.A., Choe S., Ceradini D., Martin S.R., Horuk R., MacDonald M.E., Stuhlmann H., Koup R.A., and Landau N.R. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86 (1996) 367-377
27. Lu Y., Nerurkar V.R., Dashwood W.M., Woodward C.L., Ablan S., Shikuma C.M., Grandinetti A., Chang H., Nguyen H.T., Wu Z., Yamamura Y., Boto W.O., Merriwether A., Kurata T., Detels R., and Yanagihara R. Genotype and allele frequency of a 32-base pair deletion mutation in the CCR5 gene in various ethnic groups: absence of mutation among Asians and Pacific Islanders. Int. J. Infect. Dis. 3 4 (1999) 186-191
28. Lucotte G., and Dieterlen F. More about the Viking hypothesis of origin of the delta32 mutation in the CCR5 gene conferring resistance to HIV-1 infection. Infect. Genet. Evol. 3 (2003) 293-295
29. Lucotte G., and Mercier G. Distribution of the CCR5 gene 32-bp deletion in Europe. J. Acquir. Immune. Defic. Syndr. Hum. Retrovirol. 19 (1998) 174-177
30. Martinson J.J., Chapman N.H., Rees D.C., Liu Y.T., and Clegg J.B. Global distribution of the CCR5 gene 32-basepair deletion. Nat. Genet. 16 (1997) 100-103
31. McEvedy C. The bubonic plague. Sci. Am. 258 (1988) 118-123
32. Mecsas J., Franklin G., Kuziel W.A., Brubaker R.R., Falkow S., and Mosier D.E. Evolutionary genetics: CCR5 mutation and plague protection. Nature 427 (2004) 606
33. Philpott S., Weiser B., Tarwater P., Vermund S.H., Kleeberger C.A., Gange S.J., Anastos K., Cohen M., Greenblatt R.M., Kovacs A., Minkoff H., Young M.A., Miotti P., Dupuis M., Chen C.H., and Burger H. CC chemokine receptor 5 genotype and susceptibility to transmission of human immunodeficiency virus type 1 in women. J. Infect. Dis. 187 (2003) 569-575
34. Poinar H.N., Hofreiter M., Spaulding W.G., Martin P.S., Stankiewicz B.A., Bland H., Evershed R.P., Possnert G., and Pääbo S. Molecular coproscopy: dung and diet of the extinct ground sloth Nothrotheriops shastensis. Science 281 (1998) 402-406
35. Premack B.A., and Schall T.J. Chemokine receptors: gateways to inflammation and infection. Nat. Med. 2 (1996) 1174-1178
36. Rappaport J., Cho Y.Y., Hendel H., Schwartz E.J., Schachter F., and Zagury J.F. 32 bp CCR-5 gene deletion and resistance to fast progression in HIV-1 infected heterozygotes. Lancet 349 (1997) 922-923
37. Rasmussen H.B., Timm S., Wang A.G., Søeby K., Lublin H., Fenger M., Hemmingsen R., and Werge T. Association between the CCR5 32-bp deletion allele and late onset of schizophrenia. Am. J. Psychiatry 163 3 (2006) 507-511
38. Sabeti P.C., Walsh E., Schaffner S.F., Varilly P., Fry B., Hutcheson H.B., Cullen M., Mikkelsen T.S., Roy J., Patterson N., Cooper R., Reich D., Altshuler D., O'Brien S., and Lander E.S. The case for selection at CCR5-Delta32. PLoS Biol. 3 (2005) e378
39. Salas-Alanis J.C., Mellerio J.E., Ashton G.H., and McGrath J.A. Frequency of the CCR5 gene 32 basepair deletion in Hispanic Mexicans. Clin. Exp. Dermatol. 24 (1999) 127-129
40. Samson M., Libert F., Doranz B.J., Rucker J., Liesnard C., Farber C.M., Saragosti S., Lapoumeroulie C., Cognaux J., Forceille C., Muyldermans G., Verhofstede C., Burtonboy G., Georges M., Imai T., Rana S., Yi Y., Smyth R.J., Collman R.G., Doms R.W., Vassart G., and Parmentier M. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382 (1996) 722-725
41. Schliekelman P., Garner C., and Slatkin M. Natural selection and resistance to HIV. Nature 411 6837 (2001) 545-546
42. Smoljanović M., Ristić S., and Hayward C. Historic exposure to plague and present-day frequency of CCR5del32 in two isolated islands communities of Dalmatia, Croatia. Croat. Med. J. 47 (2006) 579-584
43. Stephens J.C., Reich D.E., Goldstein D.B., Shin H.D., Smith M.W., Carrington M., Winkler C., Huttley G.A., Allikmets R., Schriml L., Gerrard B., Malasky M., Ramos M.D., Morlot S., Tzetis M., Oddoux C., di Giovine F.S., Nasioulas G., Chandler D., Aseev M., Hanson M., Kalaydjieva L., Glavac D., Gasparini P., Kanavakis E., Claustres M., Kambouris M., Ostrer H., Duff G., Baranov V., Sibul H., Metspalu A., Goldman D., Martin N., Duffy D., Schmidtke J., Estivill X., O'Brien S.J., and Dean M. Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes. Am. J. Hum. Genet. 62 (1998) 1507-1515
44. Vasan S., Zhang X., Zhang X., Kapurniotu A., Bernhagen J., Teichberg S., Basgen J., Wagle D., Shih D., Terlecky I., Bucala R., Cerami A., Egan J., and Ulrich P. An agent cleaving glucose derived protein crosslinks in vitro and in vivo. Nature 382 (1996) 275-278
45. Winkler C., An P., and O'Brien S.J. Patterns of ethnic diversity among the genes that influence AIDS. Hum. Mol. Genet. 13 (2004) R9-R19
46. Witas H.W., and Zawicki P. Allele protecting against HIV (CCR5-Δ32) identified in early medieval specimens from Central Poland. Preliminary results. Prz. Antropol. Anthropol. Rev. 69 (2006) 49-53
47. Zhang C., Fu S., Xue Y., Wang Q., Huang X., Wang B., Liu A., Ma L., Yu Y., Shi R., Lv F., Shi Z., Zhang Y., Cheng W., Ai Q., Xu F., Huang C., Chen B., Kang X., Sun Y., Zhang G., and Li P. Distribution of the CCR5 gene 32-basepair deletion in 11 Chinese populations. Anthropol. Anz. 60 3 (2002) 267-271
48. Zimmerman P.A., Buckler-White A., Alkhatib G., Spalding T., Kubofcik J., Combadiere C., Weissman D., Cohen O., Rubbert A., Lam G., Vaccarezza M., Kennedy P.E., Kumaraswami V., Giorgi J.V., Detels R., Hunter J., Chopek M., Berger E.A., Fauci A.S., Nutman T.B., and Murphy P.M. Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes, defined racial background, and quantified risk. Mol. Med. 3 (1997) 23-36