32 bp CCR-5 gene deletion and resistance to fast progression in HIV-1 infected heterozygotes [3]

Lancet

Volumn 349, Issue 9056, 1997, Pages 922-923

  Rappaport, Jay ^b   Cho, Yi Yun ^b   Hendel, Houria ^b   Schwartz, Elissa J ^b   Schachter, François ^b   Zagury, Jean François ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR;

BASE PAIRING; GENE DELETION; GENE SEQUENCE; HETEROZYGOSITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; PRIORITY JOURNAL;

EID: 0030894132     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)62697-9     Document Type: Article

References (5)

1. Cocchi F, DeVico AL, Garzino-Demi A, Arya SK, Gallo RC, Lusso P. Identification of RANTES, MIP-1A, and MIP-1B as a major HIV-suppressive factors produced by CD8+ T cells. Science 1995; 270: 1811-15.
2. Samson M, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996; 382: 722-25.
3. Liu R, Paxton WA, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996; 86: 367-77.
4. Dean M, Carrington M, Winkler C, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CCR-5 strctural gene. Science 1996; 273: 1856-62.
5. Hendel H, Cho Y-Y, Gauthier N, Rappaport J, Schachter F, Zagury J-F. Contribution of cohort studies in understanding HIV pathogenesis: introduction of the GRIV cohort and preliminary results. Biomed Pharmacother 1996; 50: 480-87.