Adiponectin and AMP kinase activator stimulate proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1 cells

BMC Cell Biology

Volumn 8, Issue , 2007, Pages

  Kanazawa, Ippei ^a   Yamaguchi, Toru ^a   Yano, Shozo ^a   Yamauchi, Mika ^a   Yamamoto, Masahiro ^a   Sugimoto, Toshitsugu ^a  

^a SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE; ADENYLATE KINASE; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ALKALINE PHOSPHATASE; BROXURIDINE; COLLAGEN TYPE 1; MESSENGER RNA; OSTEOCALCIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; ADIPONECTIN RECEPTOR; ADIPONECTIN RECEPTOR 1, MOUSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; MINERALIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PARACRINE SIGNALING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BONE MINERALIZATION; CELL STRAIN 3T3; CYTOLOGY; DRUG ANTAGONISM; METABOLISM; OBESITY; PHYSIOLOGY;

3T3 CELLS; ADENYLATE KINASE; ADIPONECTIN; ANIMALS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL PROLIFERATION; MICE; OBESITY; OSTEOBLASTS; RECEPTORS, ADIPONECTIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 39349083877     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-8-51     Document Type: Article

References (47)

1. Stewart KJ Deregis JR Turner KL Bacher AC Sung J Hees PS Tayback M Ouyang P Fitness, fatness and activity as predictors of bone mineral density in older persons J Intern Med 2002, 252:381-388. 10.1046/ j.1365-2796.2002.01050.x 12528755
2. Lim S Joung H Shin CS Lee HK Kim KS Shin EK Kim HY Lim MK Cho SI Body composition changes with age have gender-specific impacts on bone mineral density Bone 2004, 35:792-798. 10.1016/j.bone.2004.05.016 15336618
3. Lindsay R Cosman F Herrington BS Himmelstein S Bone mass and body composition in normal women J Bone Miner Res 1992, 7:55-63. 1549959
4. Felson DT Zhang Y Hannan MT Anderson JJ Effects of weight, and body mass index on bone mineral density in men and women J Bone Miner Res 1993, 8:567-573. 8511983.
5. Glauber HS Vollmer WM Nevitt MC Ensrud KE Orwoll ES Body weight versus body fat distribution, adiposity, and frame size as predictors of bone density J Clin Endocrinol Metab 1995, 80:1118-1123. 10.1210/jc.80.4.1118 7714079
6. Khosla S Atkinson EJ Riggs BL Melton LJ 3rd Relationship between body composition and bone mass in women J Bone Miner Res 1996, 11:857-863. 8725184
7. Maeda K Okubo K Shimomura I Mizuno K Matsuzawa Y Matsubara K Analysis of an expression profile of genes in the human adipose tissue Gene 1997, 190:227-235. 10.1016/S0378-1119(96)00730-5 9197538
8. Arita Y Kihara S Ouchi N Takahashi M Maeda K Miyagawa J Hotta K Shimomura I Nakamura T Miyaoka K Kuriyama H Nishida M Yamashita S Okubo K Matsubara K Muraguchi M Ohmoto Y Funahashi T Matsuzawa Y Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity Biochem Biophys Res Commun 1999, 257:79-83. 10.1006/bbrc.1999.0255 10092513
9. Combs TP Berg AH Obici S Scherer PE Rossetti L Endogenous glucose production is inhibited by the adipose-derived protein Acrp30 J Clin Invest 2001, 108:1875-1881. 209474 11748271 10.1172/JCI200114120
10. Berg AH Combs TP Du X Brownlee M Scherer PE The adipocyte-secreted protein Acrp30 enhances hepatic insulin action Nat Med 2001, 7:947-953. 10.1038/90992 11479628
11. Fruebis J Tsao TS Javorschi S Ebbets-Reed D Erickson MR Yen FT Bihain BE Lodish HF Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice Proc Natl Acad Sci USA 2001, 98:2005-2010. 29372 11172066 10.1073/pnas.041591798
12. Yamauchi T Kamon J Ito Y Tsuchida A Yokomizo T Kita S Sugiyama T Miyagishi M Hara K Tsunoda M Murakami K Ohteki T Uchida S Takekawa S Waki H Tsuno NH Shibata Y Terauchi Y Frofuel P Tobe K Koyasu S Taira K Kitamura T Shimizu T Nagai R Kadowaki T Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 2003, 423:762-769. 10.1038/nature01705 12802337
13. Yamauchi T Kamon J Minokoshi Y Ito Y Waki H Uchida S Yamashita S Noda M Kita S Ueki K Eto K Akanuma Y Froguel P Foufelle F Ferre P Carling D Kimura S Nagai R Kahn BB Kadowaki T Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase Nat Med 2002, 8:1288-1295. 10.1038/nm788 12368907
14. Tomas E Tsao TS Saha AK Murrey HE Zhang CC Itani SI Lodish HF Ruderman NB Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation Proc Natl Acad Sci USA 2002, 99:16309-16313. 138607 12456889 10.1073/pnas.222657499
15. Kadowaki T Yamauchi T Adiponectin and adiponectin receptors Endocr Rev 2005, 26:439-451. 10.1210/er.2005-0005 15897298
16. Hara K Horikoshi M Kitazato H Yamauchi T Ito C Noda M Ohashi J Froguel P Tokunaga K Nagai R Kadowaki T Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes Diabetologia 2005, 48:1307-1314. 10.1007/s00125-005-1806-3 15918014
17. Berner HS Lyngstadaas SP Spahr A Monjo M Thommesen L Drevon CA Syversen U Reseland JE Adiponectin and its receptors are expressed in bone-forming cells Bone 2004, 35:842-849. 10.1016/j.bone.2004.06.008 15454091
18. Oshima K Nampei A Matsuda M Iwaki M Fukuhara A Hashimoto J Yoshikawa H Shimomura I Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast Biochem Biophys Res Commun 2005, 331:520-526. 10.1016/j.bbrc.2005.03.210 15850790
19. Luo XH Guo LJ Yuan LQ Xie H Zhou HD Wu XP Liao EY Adiponectin stimulates human osteoblasts proliferation and differentiation via the MAPK signaling pathway Exp Cell Res 2005, 309:99-109. 10.1016/ j.yexcr.2005.05.021 15963981
20. Shinoda Y Yamaguchi M Ogata N Akune T Kubota N Yamauchi T Terauchi Y Kadowaki T Takeuchi Y Fukumoto S Ikeda T Hoshi K Chung U Nakamura K Kawaguchi H Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways J Cell Biochem 2006, 99:196-208. 10.1002/jcb.20890 16598753
21. Corton JM Gillespie JG Hawley SA Hardie DG 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem 1995, 229:558-565. 10.1111/j.1432-1033.1995.tb20498.x 7744080
22. Giri S Nath N Smith B Viollet B Singh AK Singh I 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: A possible role of AMP-activated protein kinase J Neurosci 2004, 24:479-487. 10.1523/ JNEUROSCI.4288-03.2004 14724246
23. Yang S Wei D Wang D Phimphilai M Krebsbach PH Franceschi RT In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation J Bone Miner Res 2003, 18:705-715. 10.1359/ jbmr.2003.18.4.705 12674331
24. Yokota T Meka CS Kouro T Medina KL Igarashi H Takahashi M Oritani K Funahashi T Tomiyama Y Matsuzawa Y Kincade PW Adiponectin, a fat cell product, influences the earliest lymphocyte precursors in bone marrow cultures by activation of the cyclooxygenase-prostaglandin pathway in stromal cells J Immunol 2003, 171:5091-5099. 14607907
25. Yokota T Meka CS Medina KL Igarashi H Comp PC Takahashi M Nishida M Oritani K Miyagawa J Funahashi T Tomiyama Y Matsuzawa Y Kincade PW Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins J Clin Invest 2002, 109:1303-1310. 10.1172/JCI200214506 12021245
26. Xiao G Jiang D Gopalakrishnan R Franceschi RT Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2 J Biol Chem 2002, 277:36181-36187. 10.1074/jbc.M206057200 12110689
27. Ge C Xiao G Jiang D Franceschi RT Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development J Cell Biol 2007, 176:709-718. 2064027 17325210 10.1083/jcb.200610046
28. Cheng SL Shao JS Charlton-Kachigian N Loewy AP Towler DA MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors J Biol Chem 2003, 278:45969-45977. 10.1074/ jbc.M306972200 12925529
29. Lee MH Kwon TG Park HS Wozney JM Ryoo HM BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2 Biochem Biophys Res Comm 2003, 309:689-694. 10.1016/j.bbrc.2003.08.058 12963046
30. Winder WW Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle J Appl Physiol 2001, 91:1017-1028. 11509493
31. Ruderman NB Saha AK Vavvas D Witters LA Malonyl-CoA, fuel sensing, and insulin resistance Am J Physiol 1999, 276(1 Pt 1):E1-E18. 9886945
32. Mu J Brozinick JT Jr Valladares O Bucan M Birnbaum MJ A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle Mol Cell 2001, 7:1085-1094. 10.1016/ S1097-2765(01)00251-9 11389854
33. Fryer LG Foufelle F Barnes K Baldwin SA Woods A Carling D Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells Biochem J 2002, 363:167-174. 1222463 11903059 10.1042/0264-6021:3630167
34. Minokoshi Y Kim YB Peroni OD Fryer LG Muller C Carling D Kahn BB Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase Nature 2002, 415:339-343. 10.1038/415339a 11797013
35. Goldstein JL Brown MS Regulation of the mevalonate pathway Nature 1990, 343:425-430. 10.1038/343425a0 1967820
36. Mundy G Garrett R Harris S Chan J Chen D Rossini G Boyce B Zhao M Gutierrez G Stimulation of bone formation in vitro and in rodents by statins Science 1999, 286:1946-1949. 10.1126/science.286.5446.1946 10583956
37. Garrett IR Mundy GR The role of statins as potential targets for bone formation Arthritis Res 2002, 4:237-240. 128929 12106493 10.1186/ar413
38. Kefas BA Cai Y Ling Z Heimberg H Hue L Pipeleers D Van de Casteele M AMP-activated protein kinase can induce apoptosis of insulin-producing MIN 6 cells through stimulation of c-Jun-N-terminal kinase J Mol Endocrinol 2003, 30:151-161. 10.1677/jme.0.0300151 12683939
39. Kefas BA Heimberg H Vaulont S Meisse D Hue L Pipeleers D Van de Casteele M AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase Diabetologia 2003, 46:250-254. 12627324
40. Sudo H Kodama HA Amagai Y Yamamoto S Kassai S In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria J Cell Biol 1983, 96:191-198. 10.1083/ jcb.96.1.191 6826647
41. Winzell MS Nogueiras R Dieguez C Ahren B Dual action of adiponectin on insulin secretion in insulin-resistant mice Biochem Biophys Res Commun 2004, 321:154-160. 10.1016/j.bbrc.2004.06.130 15358228
42. Yano S Mentaverri R Kanuparthi D Bandyopadhyay S Riverda A Brown EM Chattopadhyay N Functional expression of beta-chemokine receptors in osteoblasts: Role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts Endocrinology 2005, 146:2324-2335. 10.1210/ en.2005-0065 15718270
43. Livak KJ Schmittgen TD Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method Methods 2001, 25:402-408. 10.1006/meth.2001.1262 11846609
44. Fasshauer M Klein J Kralisch S Klier M Lossner U Bluher M Paschke R Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes FEBS Lett 2004, 558:27-32. 10.1016/ S0014-5793(03)01525-4 14759511
45. Lowry OH Roberts NR Wu ML Hixon WS Crawford EJ The quantitative histochemistry of brain. II. Enzyme measurements J Biol Chem 1954, 207:19-37. 13152077
46. Yamauchi M Yamaguchi T Kaji H Sugimoto T Chihara K Involvement of calcium-sensing receptor in osteoblastic differentiation of mouse MC3T3-E1 cells Am J Physiol Endocrinol Metab 2005, 288:E608-616. 10.1152/ ajpendo.00229.2004 15547142
47. Sowa H Kaji H Yamaguchi T Sugimoto T Chihara K Smad3 promotes alkaline phosphatase activity and mineralization of osteoblastic MC3T3-E1 cells J Bone miner Res 2002, 17:1190-1199. 10.1359/jbmr.2002.17.7.1190 12096832