-
1
-
-
0032562289
-
Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy
-
Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ 1998 Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science 280:574-577
-
(1998)
Science
, vol.280
, pp. 574-577
-
-
Akhter, S.A.1
Luttrell, L.M.2
Rockman, H.A.3
Iaccarino, G.4
Lefkowitz, R.J.5
Koch, W.J.6
-
2
-
-
0037154168
-
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo
-
Antos CL, McKinsey TA, Frey N et al 2002 Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci USA 99:907-912
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 907-912
-
-
Antos, C.L.1
McKinsey, T.A.2
Frey, N.3
-
3
-
-
0003047782
-
Signal transduction of cardiac myocyte hypertrophy
-
Sperelakis N, Kurachi Y, Terzic A, Cohen MV eds, 4th edn, Academic Press, San Diego, p
-
Aoki H, Izumo S 2001 Signal transduction of cardiac myocyte hypertrophy. In: Sperelakis N, Kurachi Y, Terzic A, Cohen MV (eds) Heart physiology and pathology, 4th edn, Academic Press, San Diego, p 1065-1086
-
(2001)
Heart physiology and pathology
, pp. 1065-1086
-
-
Aoki, H.1
Izumo, S.2
-
4
-
-
0030696157
-
Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates
-
Bowman JC, Steinberg SF, Jiang T, Geenen DL, Fishman GI, Buttrick PM 1997 Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates. J Clin Invest 100:2189-2195
-
(1997)
J Clin Invest
, vol.100
, pp. 2189-2195
-
-
Bowman, J.C.1
Steinberg, S.F.2
Jiang, T.3
Geenen, D.L.4
Fishman, G.I.5
Buttrick, P.M.6
-
5
-
-
0038651918
-
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling
-
Braz JC, Bueno OF, Liang Q et al 2003 Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. J Clin Invest 111:1475-1186
-
(2003)
J Clin Invest
, vol.111
, pp. 1475-1186
-
-
Braz, J.C.1
Bueno, O.F.2
Liang, Q.3
-
6
-
-
0034383952
-
The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
-
Bueno OF, De Windt LJ, Tymitz KM et al 2000 The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J 19:6341-6350
-
(2000)
EMBO J
, vol.19
, pp. 6341-6350
-
-
Bueno, O.F.1
De Windt, L.J.2
Tymitz, K.M.3
-
7
-
-
0037007016
-
Impaired cardiac hypertrophic response in Calcineurin Abeta-deficient mice
-
Bueno OF, Wilkins BJ, Tymitz KM et al 2002 Impaired cardiac hypertrophic response in Calcineurin Abeta-deficient mice. Proc Natl Acad Sci USA 99:4586-4591
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4586-4591
-
-
Bueno, O.F.1
Wilkins, B.J.2
Tymitz, K.M.3
-
9
-
-
0032881288
-
AKT/PKB and other D3 phosphoinositideregulated kinases: Kinase activation by phosphoinositide- dependent phosphorylation
-
Chan TO, Rittenhouse SE, Tsichlis PN 1999 AKT/PKB and other D3 phosphoinositideregulated kinases: kinase activation by phosphoinositide- dependent phosphorylation. Annu Rev Biochem 68:965-1014
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 965-1014
-
-
Chan, T.O.1
Rittenhouse, S.E.2
Tsichlis, P.N.3
-
10
-
-
0026349336
-
Regulation of cardiac gene expression during myocardial growth and hypertrophy: Molecular studies of an adaptive physiologic response
-
Chien KR, Knowlton KU, Zhu H, Chien S 1991 Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. Faseb J 5:3037-3046
-
(1991)
Faseb J
, vol.5
, pp. 3037-3046
-
-
Chien, K.R.1
Knowlton, K.U.2
Zhu, H.3
Chien, S.4
-
11
-
-
0027418496
-
Transcriptional regulation during cardiac growth and development
-
Chien KR, Zhu H, Knowlton KU et al 1993 Transcriptional regulation during cardiac growth and development. Annu Rev Physiol 55:77-95
-
(1993)
Annu Rev Physiol
, vol.55
, pp. 77-95
-
-
Chien, K.R.1
Zhu, H.2
Knowlton, K.U.3
-
12
-
-
0028788935
-
The 70 kDa S6 kinase: Regulation of a kinase with multiple roles in mitogenic signalling
-
Chou MM, Blenis J 1995 The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Curr Opin Cell Biol 7:806-814
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 806-814
-
-
Chou, M.M.1
Blenis, J.2
-
13
-
-
0032694866
-
Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases
-
Choukroun G, Hajjar R, Fry S et al 1999 Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases. J Clin Invest 104:391-398
-
(1999)
J Clin Invest
, vol.104
, pp. 391-398
-
-
Choukroun, G.1
Hajjar, R.2
Fry, S.3
-
14
-
-
0031041979
-
Report of the national heart, lung, and blood institute special emphasis panel on heart failure research
-
Cohn JN, Bristow MR, Chien KR et al 1997 Report of the national heart, lung, and blood institute special emphasis panel on heart failure research. Circulation 95:766-770
-
(1997)
Circulation
, vol.95
, pp. 766-770
-
-
Cohn, J.N.1
Bristow, M.R.2
Chien, K.R.3
-
15
-
-
0037125980
-
Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice
-
Condorelli G, Drusco A, Stassi G et al 2002 Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci USA 99:12333-12338
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12333-12338
-
-
Condorelli, G.1
Drusco, A.2
Stassi, G.3
-
16
-
-
0033179153
-
Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease
-
Cook SA, Sugden PH, Clerk A 1999 Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease. J Mol Cell Cardiol 31:1429-1434
-
(1999)
J Mol Cell Cardiol
, vol.31
, pp. 1429-1434
-
-
Cook, S.A.1
Sugden, P.H.2
Clerk, A.3
-
17
-
-
0037151101
-
Transcriptional effects of chronic Akt activation in the heart
-
Cook SA, Matsui T, Li L, Rosenzweig A 2002 Transcriptional effects of chronic Akt activation in the heart. J Biol Chem 277:22528-22533
-
(2002)
J Biol Chem
, vol.277
, pp. 22528-22533
-
-
Cook, S.A.1
Matsui, T.2
Li, L.3
Rosenzweig, A.4
-
18
-
-
0023161154
-
Cardiocyte adaptation to chronically altered load
-
Cooper Gt 1987 Cardiocyte adaptation to chronically altered load. Annu Rev Physiol 49:501-518
-
(1987)
Annu Rev Physiol
, vol.49
, pp. 501-518
-
-
Cooper, G.1
-
19
-
-
0030610854
-
Transgenic Galphaq overexpression induces cardiac contractile failure in mice
-
D'Angelo DD, Sakata Y, Lorenz JN et al 1997 Transgenic Galphaq overexpression induces cardiac contractile failure in mice. Proc Natl Acad Sci USA 94:8121-8126
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8121-8126
-
-
D'Angelo, D.D.1
Sakata, Y.2
Lorenz, J.N.3
-
20
-
-
0033228631
-
Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice
-
Delaughter MC, Taffet GE, Fiorotto ML, Entman ML, Schwartz RJ 1999 Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice. Faseb J 13:1923-1929
-
(1999)
Faseb J
, vol.13
, pp. 1923-1929
-
-
Delaughter, M.C.1
Taffet, G.E.2
Fiorotto, M.L.3
Entman, M.L.4
Schwartz, R.J.5
-
21
-
-
0033987656
-
Therapeutic options in minimizing left ventricular hypertrophy
-
Devereux RB 2000 Therapeutic options in minimizing left ventricular hypertrophy. Am Heart J 139(1 Pt 2):S9-14
-
(2000)
Am Heart J
, vol.139
, Issue.1 PART 2
-
-
Devereux, R.B.1
-
22
-
-
0038380271
-
Phenotyping hypertrophy: Eschew obfuscation
-
Dorn GW 2nd, Robbins J, Sugden PH 2003 Phenotyping hypertrophy: eschew obfuscation. Circ Res 92:1171-1175
-
(2003)
Circ Res
, vol.92
, pp. 1171-1175
-
-
Dorn 2nd, G.W.1
Robbins, J.2
Sugden, P.H.3
-
23
-
-
0028799490
-
Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure
-
Duerr RL, Huang S, Miraliakbar HR, Clark R, Chien KR, Ross J Jr 1995 Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure. J Clin Invest 95:619-627
-
(1995)
J Clin Invest
, vol.95
, pp. 619-627
-
-
Duerr, R.L.1
Huang, S.2
Miraliakbar, H.R.3
Clark, R.4
Chien, K.R.5
Ross Jr, J.6
-
24
-
-
0030828913
-
Impact of different sports and training on cardiac structure and function
-
Fagard RH 1997 Impact of different sports and training on cardiac structure and function. Cardiol Clin 15:397-412
-
(1997)
Cardiol Clin
, vol.15
, pp. 397-412
-
-
Fagard, R.H.1
-
25
-
-
0000155566
-
Cardiac hypertrophy: Morphological aspects
-
Zak R ed, Raven Press, New York, p
-
Ferrans VJ 1984 Cardiac hypertrophy: Morphological aspects. In: Zak R (ed) Growth of the heart in health and disease. Raven Press, New York, p 187-239
-
(1984)
Growth of the heart in health and disease
, pp. 187-239
-
-
Ferrans, V.J.1
-
26
-
-
0037267631
-
Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth
-
Fiorotto ML, Schwartz RJ, Delaughter MC 2003 Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth. Faseb J 17:59-60
-
(2003)
Faseb J
, vol.17
, pp. 59-60
-
-
Fiorotto, M.L.1
Schwartz, R.J.2
Delaughter, M.C.3
-
27
-
-
0004214478
-
-
Froelicher VF, Myers JN eds, W.B. Saunders Company, Philadelphia
-
Froelicher VF, Myers JN 2000 In: Froelicher VF, Myers JN (eds) Exercise and the heart. W.B. Saunders Company, Philadelphia
-
(2000)
Exercise and the heart
-
-
Froelicher, V.F.1
Myers, J.N.2
-
28
-
-
0029780935
-
Angiotensin receptor 1 blockade does not prevent physiological cardiac hypertrophy in the adult rat
-
Geenen DL, Malhotra A, Buttrick PM 1996 Angiotensin receptor 1 blockade does not prevent physiological cardiac hypertrophy in the adult rat. J Appl Physiol 81:816-821
-
(1996)
J Appl Physiol
, vol.81
, pp. 816-821
-
-
Geenen, D.L.1
Malhotra, A.2
Buttrick, P.M.3
-
29
-
-
0344011683
-
Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy
-
Hahn HS, Marreez Y, Odley A et al 2003 Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy. Circ Res 93:1111-1119
-
(2003)
Circ Res
, vol.93
, pp. 1111-1119
-
-
Hahn, H.S.1
Marreez, Y.2
Odley, A.3
-
30
-
-
0034768818
-
Echocardiographic differentiation of pathological and physiological left ventricular hypertrophy
-
Hildick-Smith DJ, Shapiro LM 2001 Echocardiographic differentiation of pathological and physiological left ventricular hypertrophy. Heart 85:615-619
-
(2001)
Heart
, vol.85
, pp. 615-619
-
-
Hildick-Smith, D.J.1
Shapiro, L.M.2
-
31
-
-
0038814317
-
Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A
-
Holtwick R, van Eickels M, Skryabin BV et al 2003 Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A. J Clin Invest 111:1399-1407
-
(2003)
J Clin Invest
, vol.111
, pp. 1399-1407
-
-
Holtwick, R.1
van Eickels, M.2
Skryabin, B.V.3
-
32
-
-
0033954454
-
Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes
-
Horio T, Nishikimi T, Yoshihara F, Matsuo H, Takishita S, Kangawa K 2000 Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes. Hypertension 35(1 Pt 1):19-24
-
(2000)
Hypertension
, vol.35
, Issue.1 PART 1
, pp. 19-24
-
-
Horio, T.1
Nishikimi, T.2
Yoshihara, F.3
Matsuo, H.4
Takishita, S.5
Kangawa, K.6
-
33
-
-
0029976804
-
Postnatal growth of the heart and its blood vessels
-
Hudlicka O, Brown MD 1996 Postnatal growth of the heart and its blood vessels. J Vasc Res 33:266-287
-
(1996)
J Vasc Res
, vol.33
, pp. 266-287
-
-
Hudlicka, O.1
Brown, M.D.2
-
34
-
-
0033592754
-
Signaling pathways for cardiac hypertrophy and failure
-
Hunter JJ, Chien KR 1999 Signaling pathways for cardiac hypertrophy and failure. N Engl J Med 341:1276-1283
-
(1999)
N Engl J Med
, vol.341
, pp. 1276-1283
-
-
Hunter, J.J.1
Chien, K.R.2
-
35
-
-
0035665581
-
Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat
-
Iemitsu M, Miyauchi T, Maeda S et al 2001 Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat. Am J Physiol Regul Integr Comp Physiol 281:R2029-2036
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.281
-
-
Iemitsu, M.1
Miyauchi, T.2
Maeda, S.3
-
36
-
-
0041932511
-
Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator
-
Inagaki K, Hahn HS, Dorn GW 2nd, Mochly-Rosen D 2003 Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator. Circulation 108:869-875
-
(2003)
Circulation
, vol.108
, pp. 869-875
-
-
Inagaki, K.1
Hahn, H.S.2
Dorn 2nd, G.W.3
Mochly-Rosen, D.4
-
37
-
-
0023713203
-
Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload
-
Izumo S, Nadal-Ginard B, Mahdavi V 1988 Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci USA 85:339-343
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 339-343
-
-
Izumo, S.1
Nadal-Ginard, B.2
Mahdavi, V.3
-
38
-
-
0028067369
-
Cardiac adaptations to chronic exercise in mice
-
Kaplan ML, Cheslow Y, Vikstrom K et al 1994 Cardiac adaptations to chronic exercise in mice. Am J Physiol 267(3 Pt 2):H1167-1173
-
(1994)
Am J Physiol
, vol.267
, Issue.3 PART 2
-
-
Kaplan, M.L.1
Cheslow, Y.2
Vikstrom, K.3
-
39
-
-
0035956914
-
A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy
-
Kishimoto I, Rossi K, Garbers DL 2001 A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy. Proc Natl Acad Sci USA 98:2703-2706
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2703-2706
-
-
Kishimoto, I.1
Rossi, K.2
Garbers, D.L.3
-
40
-
-
0034017485
-
Exercise and mechanical loading increase periosteal bone formation and whole bone strength in C57BL/6J mice but not in C3H/Hej mice
-
Kodama Y, Umemura Y, Nagasawa S et al 2000 Exercise and mechanical loading increase periosteal bone formation and whole bone strength in C57BL/6J mice but not in C3H/Hej mice. Calcif Tissue Int 66:298-306
-
(2000)
Calcif Tissue Int
, vol.66
, pp. 298-306
-
-
Kodama, Y.1
Umemura, Y.2
Nagasawa, S.3
-
41
-
-
0032947177
-
Serum levels of total and free IGF-I and IGFBP-3 are increased and maintained in long-term training
-
Koziris LP, Hickson RC, Chatterton RT Jr et al 1999 Serum levels of total and free IGF-I and IGFBP-3 are increased and maintained in long-term training. J Appl Physiol 86:1436-1442
-
(1999)
J Appl Physiol
, vol.86
, pp. 1436-1442
-
-
Koziris, L.P.1
Hickson, R.C.2
Chatterton Jr, R.T.3
-
42
-
-
10544232615
-
Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency
-
Lembo G, Rockman HA, Hunter JJ et al 1996 Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency. J Clin Invest 98:2648-2655
-
(1996)
J Clin Invest
, vol.98
, pp. 2648-2655
-
-
Lembo, G.1
Rockman, H.A.2
Hunter, J.J.3
-
43
-
-
0025280867
-
Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
-
Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP 1990 Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322:1561-1566
-
(1990)
N Engl J Med
, vol.322
, pp. 1561-1566
-
-
Levy, D.1
Garrison, R.J.2
Savage, D.D.3
Kannel, W.B.4
Castelli, W.P.5
-
44
-
-
0344924887
-
Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: Dichotomy between cultured myocytes and animal models
-
Liang Q, Molkentin JD 2003 Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: dichotomy between cultured myocytes and animal models. J Mol Cell Cardiol 35:1385-1394
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1385-1394
-
-
Liang, Q.1
Molkentin, J.D.2
-
45
-
-
0141642015
-
c-Jun N-terminal kinases ( JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling
-
Liang Q, Bueno OF, Wilkins BJ, Kuan CY, Xia Y, Molkentin JD 2003 c-Jun N-terminal kinases ( JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling. EMBO J 22:5079-5089
-
(2003)
EMBO J
, vol.22
, pp. 5079-5089
-
-
Liang, Q.1
Bueno, O.F.2
Wilkins, B.J.3
Kuan, C.Y.4
Xia, Y.5
Molkentin, J.D.6
-
46
-
-
27144536566
-
Class IA Phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy
-
Luo J, McMullen JR, Sobkiw CL et al 2005 Class IA Phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy. Mol Cell Biol 25:9491-9502
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9491-9502
-
-
Luo, J.1
McMullen, J.R.2
Sobkiw, C.L.3
-
47
-
-
0033860692
-
Genetic dissection of cardiac growth control pathways
-
MacLellan WR, Schneider MD 2000 Genetic dissection of cardiac growth control pathways. Annu Rev Physiol 62:289-319
-
(2000)
Annu Rev Physiol
, vol.62
, pp. 289-319
-
-
MacLellan, W.R.1
Schneider, M.D.2
-
48
-
-
0037151104
-
Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart
-
Matsui T, Li L, Wu JC et al 2002 Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem 277:22896-22901
-
(2002)
J Biol Chem
, vol.277
, pp. 22896-22901
-
-
Matsui, T.1
Li, L.2
Wu, J.C.3
-
49
-
-
0142027759
-
Phosphoinositide 3-kinase(p110?) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
-
McMullen JR, Shioi T, Zhang L et al 2003 Phosphoinositide 3-kinase(p110?) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci USA 100:12355-12360
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12355-12360
-
-
McMullen, J.R.1
Shioi, T.2
Zhang, L.3
-
50
-
-
10744223902
-
The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110?) pathway
-
McMullen JR, Shioi T, Huang WY et al 2004a The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110?) pathway. J Biol Chem 279:4782-4793
-
(2004)
J Biol Chem
, vol.279
, pp. 4782-4793
-
-
McMullen, J.R.1
Shioi, T.2
Huang, W.Y.3
-
51
-
-
3042608187
-
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload
-
McMullen JR, Sherwood MC, Tarnavski O et al 2004b Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload. Circulation 109:3050-3055
-
(2004)
Circulation
, vol.109
, pp. 3050-3055
-
-
McMullen, J.R.1
Sherwood, M.C.2
Tarnavski, O.3
-
52
-
-
3042707485
-
Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy
-
McMullen JR, Shioi T, Zhang L et al 2004c Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy. Mol Cell Biol 24:6231-6240
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6231-6240
-
-
McMullen, J.R.1
Shioi, T.2
Zhang, L.3
-
53
-
-
0037133571
-
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq
-
Minamino T, Yujiri T, Terada N et al 2002 MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. Proc Natl Acad Sci USA 99:3866-3871
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3866-3871
-
-
Minamino, T.1
Yujiri, T.2
Terada, N.3
-
54
-
-
0037651250
-
A friend within the heart: Natriuretic peptide receptor signaling
-
Molkentin JD 2003 A friend within the heart: natriuretic peptide receptor signaling. J Clin Invest 111:1275-1277
-
(2003)
J Clin Invest
, vol.111
, pp. 1275-1277
-
-
Molkentin, J.D.1
-
55
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
Molkentin JD, Lu JR, Antos CL et al 1998 A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93:215-228
-
(1998)
Cell
, vol.93
, pp. 215-228
-
-
Molkentin, J.D.1
Lu, J.R.2
Antos, C.L.3
-
56
-
-
0035941414
-
Increased cardiac sympathetic activity and insulin-like growth factor-I formation are associated with physiological hypertrophy in athletes
-
Neri Serneri GG, Boddi M, Modesti PA et al 2001a Increased cardiac sympathetic activity and insulin-like growth factor-I formation are associated with physiological hypertrophy in athletes. Circ Res 89:977-982
-
(2001)
Circ Res
, vol.89
, pp. 977-982
-
-
Neri Serneri, G.G.1
Boddi, M.2
Modesti, P.A.3
-
57
-
-
0034969427
-
Activation of cardiac renin-angiotensin system in unstable angina
-
Neri Serneri GG, Boddi M, Poggesi L et al 2001b Activation of cardiac renin-angiotensin system in unstable angina. J Am Coll Cardiol 38:49-55
-
(2001)
J Am Coll Cardiol
, vol.38
, pp. 49-55
-
-
Neri Serneri, G.G.1
Boddi, M.2
Poggesi, L.3
-
58
-
-
0034705270
-
Calcineurin signaling and muscle remodeling
-
Olson EN, Williams RS 2000 Calcineurin signaling and muscle remodeling. Cell 101:689-692
-
(2000)
Cell
, vol.101
, pp. 689-692
-
-
Olson, E.N.1
Williams, R.S.2
-
59
-
-
0029084044
-
Favorable left ventricular remodeling following large myocardial infarction by exercise training. Effect on ventricular morphology and gene expression
-
Orenstein TL, Parker TG, Butany JW et al 1995 Favorable left ventricular remodeling following large myocardial infarction by exercise training. Effect on ventricular morphology and gene expression. J Clin Invest 96:858-866
-
(1995)
J Clin Invest
, vol.96
, pp. 858-866
-
-
Orenstein, T.L.1
Parker, T.G.2
Butany, J.W.3
-
60
-
-
9444269796
-
Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice
-
Reiss K, Cheng W, Ferber A et al 1996a Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc Natl Acad Sci USA 93:8630-8635
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8630-8635
-
-
Reiss, K.1
Cheng, W.2
Ferber, A.3
-
61
-
-
0030449503
-
Phosphatidylserine directs differential phosphorylation of actin and glyceraldehyde-3-phosphate dehydrogenase by protein kinase C: Possible implications for regulation of actin polymerization
-
Reiss N, Oplatka A, Hermon J, Naor Z 1996b Phosphatidylserine directs differential phosphorylation of actin and glyceraldehyde-3-phosphate dehydrogenase by protein kinase C: possible implications for regulation of actin polymerization. Biochem Mol Biol Int 40:1191-1200
-
(1996)
Biochem Mol Biol Int
, vol.40
, pp. 1191-1200
-
-
Reiss, N.1
Oplatka, A.2
Hermon, J.3
Naor, Z.4
-
62
-
-
0031907281
-
Pathological versus physiological left ventricular hypertrophy: A review
-
Richey PA, Brown SP 1998 Pathological versus physiological left ventricular hypertrophy: a review. J Sports Sci 16:129-141
-
(1998)
J Sports Sci
, vol.16
, pp. 129-141
-
-
Richey, P.A.1
Brown, S.P.2
-
64
-
-
0035853110
-
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
-
Rothermel BA, McKinsey TA, Vega RB et al 2001 Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proc Natl Acad Sci USA 98:3328-3333
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3328-3333
-
-
Rothermel, B.A.1
McKinsey, T.A.2
Vega, R.B.3
-
65
-
-
0036074371
-
The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy
-
Sadoshima J, Montagne O, Wang Q et al 2002 The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy. J Clin Invest 110:271-279
-
(2002)
J Clin Invest
, vol.110
, pp. 271-279
-
-
Sadoshima, J.1
Montagne, O.2
Wang, Q.3
-
67
-
-
0022550803
-
Chronic swimming reverses cardiac dysfunction and myosin abnormalities in hypertensive rats
-
Schaible TF, Malhotra A, Ciambrone GJ, Scheuer J 1986 Chronic swimming reverses cardiac dysfunction and myosin abnormalities in hypertensive rats. J Appl Physiol 60:1435-1441
-
(1986)
J Appl Physiol
, vol.60
, pp. 1435-1441
-
-
Schaible, T.F.1
Malhotra, A.2
Ciambrone, G.J.3
Scheuer, J.4
-
68
-
-
0020353614
-
Physiologic cardiac hypertrophy corrects contractile protein abnormalities associated with pathologic hypertrophy in rats
-
Scheuer J, Malhotra A, Hirsch C, Capasso J, Schaible TF 1982 Physiologic cardiac hypertrophy corrects contractile protein abnormalities associated with pathologic hypertrophy in rats. J Clin Invest 70:1300-1305
-
(1982)
J Clin Invest
, vol.70
, pp. 1300-1305
-
-
Scheuer, J.1
Malhotra, A.2
Hirsch, C.3
Capasso, J.4
Schaible, T.F.5
-
69
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
-
Shioi T, Kang PM, Douglas PS et al 2000 The conserved phosphoinositide 3-kinase pathway determines heart size in mice. Embo J 19:2537-2548
-
(2000)
Embo J
, vol.19
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
-
70
-
-
0036200937
-
Akt/protein kinase B promotes organ growth in transgenic mice
-
Shioi T, McMullen JR, Kang PM et al 2002 Akt/protein kinase B promotes organ growth in transgenic mice. Mol Cell Biol 22:2799-2809
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2799-2809
-
-
Shioi, T.1
McMullen, J.R.2
Kang, P.M.3
-
71
-
-
0037382861
-
Rapamycin attenuates load-induced cardiac hypertrophy in mice
-
Shioi T, McMullen JR, Tarnavski O et al 2003 Rapamycin attenuates load-induced cardiac hypertrophy in mice. Circulation 107:1664-1670
-
(2003)
Circulation
, vol.107
, pp. 1664-1670
-
-
Shioi, T.1
McMullen, J.R.2
Tarnavski, O.3
-
72
-
-
1842830427
-
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes
-
Shiraishi I, Melendez J, Ahn Y et al 2004 Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res 884-891
-
(2004)
Circ Res
, pp. 884-891
-
-
Shiraishi, I.1
Melendez, J.2
Ahn, Y.3
-
73
-
-
0031669940
-
A cellular mechanisms of cardiac hypertrophy
-
Sugden PH, Clerk 1998 A cellular mechanisms of cardiac hypertrophy. J Mol Med 76:725-746
-
(1998)
J Mol Med
, vol.76
, pp. 725-746
-
-
Sugden, P.H.1
Clerk2
-
74
-
-
0034705485
-
Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy
-
Takeishi Y, Ping P, Bolli R, Kirkpatrick DL, Hoit BD, Walsh RA 2000 Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy. Circ Res 86:1218-1223
-
(2000)
Circ Res
, vol.86
, pp. 1218-1223
-
-
Takeishi, Y.1
Ping, P.2
Bolli, R.3
Kirkpatrick, D.L.4
Hoit, B.D.5
Walsh, R.A.6
-
75
-
-
0031854870
-
Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice
-
Tanaka N, Ryoke T, Hongo M et al 1998 Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice. Am J Physiol 275(2 Pt 2):H393-399
-
(1998)
Am J Physiol
, vol.275
, Issue.2 PART 2
-
-
Tanaka, N.1
Ryoke, T.2
Hongo, M.3
-
76
-
-
1542319162
-
Mouse cardiac surgery: Comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies
-
Tarnavski O, McMullen JR, Schinke M, Nie Q, Kong S, Izumo S 2004 Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies. Physiol Genomics 16:349-360
-
(2004)
Physiol Genomics
, vol.16
, pp. 349-360
-
-
Tarnavski, O.1
McMullen, J.R.2
Schinke, M.3
Nie, Q.4
Kong, S.5
Izumo, S.6
-
77
-
-
0030707562
-
TOR signalling and control of cell growth
-
Thomas G, Hall MN 1997 TOR signalling and control of cell growth. Curr Opin Cell Biol 9:782-787
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 782-787
-
-
Thomas, G.1
Hall, M.N.2
-
78
-
-
0030992837
-
Signalling through the lipid products of phosphoinositide-3-OH kinase
-
Toker A, Cantley LC 1997 Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387:673-676
-
(1997)
Nature
, vol.387
, pp. 673-676
-
-
Toker, A.1
Cantley, L.C.2
-
80
-
-
0030875166
-
Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy
-
Wakasaki H, Koya D, Schoen FJ et al 1997 Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy. Proc Natl Acad Sci USA 94:9320-9325
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9320-9325
-
-
Wakasaki, H.1
Koya, D.2
Schoen, F.J.3
-
81
-
-
0025770664
-
Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system
-
Weber KT, Brilla CG 1991 Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 83:1849-1865
-
(1991)
Circulation
, vol.83
, pp. 1849-1865
-
-
Weber, K.T.1
Brilla, C.G.2
-
82
-
-
85047680324
-
Myocardial fibrosis: Functional significance and regulatory factors
-
Weber KT, Brilla CG, Janicki JS 1993 Myocardial fibrosis: functional significance and regulatory factors. Cardiovasc Res 27:341-348
-
(1993)
Cardiovasc Res
, vol.27
, pp. 341-348
-
-
Weber, K.T.1
Brilla, C.G.2
Janicki, J.S.3
-
83
-
-
0035166852
-
Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes
-
Wettschureck N, Rutten H, Zywietz A et al 2001 Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes. Nat Med 7:1236-1240
-
(2001)
Nat Med
, vol.7
, pp. 1236-1240
-
-
Wettschureck, N.1
Rutten, H.2
Zywietz, A.3
-
84
-
-
0347320747
-
Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
-
Wilkins BJ, Dai YS, Bueno OF et al 2004 Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 94:110-118
-
(2004)
Circ Res
, vol.94
, pp. 110-118
-
-
Wilkins, B.J.1
Dai, Y.S.2
Bueno, O.F.3
-
85
-
-
0028158743
-
Effect of growth hormone administration and treadmill exercise on serum and skeletal IGF-I in rats
-
Yeh JK, Aloia JF, Chen M, Ling N, Koo HC, Millard WJ 1994 Effect of growth hormone administration and treadmill exercise on serum and skeletal IGF-I in rats. Am J Physiol 266(1 Pt 1):E129-135
-
(1994)
Am J Physiol
, vol.266
, Issue.1 PART 1
-
-
Yeh, J.K.1
Aloia, J.F.2
Chen, M.3
Ling, N.4
Koo, H.C.5
Millard, W.J.6
|