Persistent induction of the chemokine receptor CXCR4 by TGF-β1 on synovial T cells contributes to their accumulation within the rheumatoid synovium

Journal of Immunology

Volumn 165, Issue 6, 2000, Pages 3423-3429

  Buckley, C D ^a   Amft, N ^a   Bradfield, P F ^a   Pilling, D ^a   Ross, E ^a   Arenzana Seisdedos, F ^a   Amara, A ^a   Curnow, S J ^a   Lord, J M ^a   Scheel Toellner, D ^a   Salmon, M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; FIBRONECTIN; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; ISOPROTEIN; LIGAND; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVIUM; T LYMPHOCYTE;

EID: 0034665323     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.6.3423     Document Type: Article

References (38)

1. Science medicine and the future: Treatment of rheumatoid arthritis
2. The role of T-lymphocytes in rheumatoid arthritis
3. Subpopulations of primed T helper cells in rheumatoid arthritis
4. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis
5. Inhibition of T cell apoptosis in the rheumatoid synovium
6. Interferon-β mediates stromal cell rescue of T cells from apoptosis
7. 1 integrins in chronic inflammatory diseases
8. High avidity state of leukocyte function-associated antigen-1 on rheumatoid synovial fluid T lymphocytes
9. Lymphocyte homing and homeostasis
10. Multistep navigation and the combinatorial control of leukocyte chemotaxis
11. Chemokines and leukocyte traffic
12. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
13. Chemokines and cell migration in secondary lymphoid organs
14. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions
15. + T lymphocytes into inflamed joints of rheumatoid arthritis
16. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
17. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow environment
18. A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: Their functions in development, haematopoiesis and HIV infection
19. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
20. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
21. Stromal cell-derived factor 1 (SDF-1) and antenatal human B cell lymphopoiesis: Expression of SDF-1 by mesothelial cells and biliary ductal plate epithelial cells
22. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
23. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
24. IL-4 induces functional cell surface expression of CXCR4 on human T cells
25. HIV co-receptor downregulation as antiviral principle: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to the inhibition of HIV replication
26. Transforming growth factor-β and cellular immune responses in synovial fluids
27. Active and latent forms of transforming growth factor β activity in synovial effusions
28. Use of a differential subtraction method to identify genes that characterize the phenotype of cultured rheumatoid arthritis synoviocytes
29. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
30. Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1α
31. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells
32. Regulation of immune responses by TGF-β
33. Joint inflammation and cartilage destruction may occur uncoupled
34. Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor β
35. + cells on vascular endothelium under flow
36. Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin
37. Expression and regulation of β7 integrins on mouse lymphocytes: Relevance to the mucosal immune system
38. 7 and its ligand E-cadherin in the synovium of patients with rheumatoid arthritis