Conservation of structure, signaling and pharmacology between two serotonin receptor subtypes from decapod crustaceans, Panulirus interruptus and Procambarus clarkii

Journal of Experimental Biology

Volumn 211, Issue 1, 2008, Pages 92-105

  Spitzer, Nadja ^a,b   Edwards, Donald H ^a   Baro, Deborah J ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b MARSHALL UNIVERSITY   (United States)

Author keywords

Agonist; Amine; Antagonist; Cloning; G protein coupled receptor; Neuromodulation

Indexed keywords

AMINE; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; CRAYFISH; DOG; DOSE RESPONSE; DRUG EFFECT; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PALINURIDAE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

AMINES; AMINO ACID SEQUENCE; ANIMALS; ASTACOIDEA; CELL LINE; CONSERVED SEQUENCE; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PALINURIDAE; RECEPTORS, SEROTONIN, 5-HT1; RECEPTORS, SEROTONIN, 5-HT2; SEQUENCE ANALYSIS, PROTEIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SIGNAL TRANSDUCTION;

ANIMALIA; ARTHROPODA; ASTACOIDEA; CRUSTACEA; INVERTEBRATA; MAMMALIA; PANULIRUS INTERRUPTUS; PROCAMBARUS CLARKII;

EID: 38949190610     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.012450     Document Type: Article

References (60)

1. Angers, A., Storozhuk, M. V., Duchaine, T., Castellucci, V. F. and DesGroseillers, L. (1998). Cloning and functional expression of an Aplysia 5HT receptor negatively coupled to adenylate cyclase. J. Neurosci. 18, 5586-5593.
2. Ausubel, A., Brent, R., Kinston, R., Moore, D., Seidman, J., Smith, J. A. and Struhl, K. (1990). Current Protocols in Molecular Biology. New York: Greene Publishing Associates and Wiley Interscience.
3. Ballesteros, J. A. and Weinstein, H. (1995). Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein coupled receptors. Methods Neurosci. 25, 366-428.
4. Barbas, D., Zappulla, J. P., Angers, S., Bouvier, M., Castellucci, V. F. and DesGroseillers, L. (2002). Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica. J. Neurochem. 80, 335-345.
5. Barbas, D., DesGroseillers, L., Castellucci, V. F., Carew, T. J. and Marinesco, S. (2003). Multiple serotonergic mechanisms contributing to sensitization in Aplysia: evidence of diverse serotonin receptor subtypes. Learn. Mem. 10, 373-386.
6. Bard, J. A., Zgombick, J., Adham, N., Vaysse, P., Branchek, T. A. and Weinshank, R. L. (1993). Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase. J. Biol. Chem. 268, 23422-23426.
7. Baro, D. J., Cole, C. L., Zarrin, A. R., Hughes, S. and Harris-Warrick, R. M. (1994). Shab gene expression in identified neurons of the pyloric network in the lobster stomatogastric ganglion. Recept. Channels 2, 193-205.
8. Berg, K. A., Harvey, J. A., Spampinato, U. and Clarke, W. P. (2005). Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors. Trends Pharmacol. Sci. 26, 625-630.
9. Bicker, G. (1999). Biogenic amines in the brain of the honeybee: cellular distribution, development, and behavioral functions. Microsc. Res. Tech. 44, 166-178.
10. Blenau, W. and Baumann, A. (2001). Molecular and pharmacological properties of insect biogenic amine receptors: lessons from Drosophila melanogaster and Apis mellifera. Arch. Insect Biochem. Physiol. 48, 13-38.
11. Chen, A., Holmes, S. P. and Pietrantonio, P. V. (2004). Molecular cloning and functional expression of a serotonin receptor from the Southern cattle tick, Boophilus microplus (Acari: Ixodidae). Insect Mol. Biol. 13, 45-54.
12. Clark, M. C. and Baro, D. J. (2007). Arthropod D2 receptors positively couple with cAMP through the Gi/o protein family. Comp. Biochem. Physiol. 146B, 9-19.
13. Clark, M. C., Dever, T. E., Dever, J. J., Xu, P., Rehder, V., Sosa, M. A. and Baro, D. J. (2004). Arthropod 5-HT2 receptors: a neurohormonal receptor in decapod crustaceans that displays agonist independent activity resulting from an evolutionary alteration to the DRY motif. J. Neurosci. 24, 3421-3435.
14. Clements, J. D. (1996). Transmitter timecourse in the synaptic cleft: its role in central synaptic function. Trends Neurosci. 19, 163-171.
15. Colas, J. F., Launay, J. M., Kellerman, O., Rosay, P. and Maroteaux, L. (1995). Drosophila 5-HT2 serotonin receptor: Coexpression with fushi-tarazu during segmentation. Proc. Natl. Acad. Sci. USA 92, 5441-5445.
16. Cosi, C. and Koek, W. (2000). The putative "silent" 5-HT (1A) receptor antagonist, WAY 100635, has inverse agonist properties at cloned human 5-HT (1A) receptors. Eur. J. Pharmacol. 401, 9-15.
17. Edwards, D. H. and Kravitz, E. A. (1997). Serotonin, social status and aggression. Curr. Opin. Neurobiol. 7, 812-819.
18. Edwards, D. H., Heitler, W. J. and Krasne, F. B. (1999). Fifty years of a command neuron: the neurobiology of escape behaviour in the crayfish. Trends Neurosci. 22, 153-161.
19. Flamm, R. E. and Harris-Warrick, R. M. (1986). Aminergic modulation in lobster stomatogastric ganglion. II. Target neurons of dopamine, octopamine, and serotonin within the pyloric circuit. J. Neurophysiol. 55, 866-881.
20. Frerking, M. and Wilson, M. (1996). Saturation of postsynaptic receptors at central synapses? Curr. Opin. Neurobiol. 6, 395-403.
21. Friedman, J., Babu, B. and Clark, R. B. (2002). Beta (2)-adrenergic receptor lacking the cyclic AMP-dependent protein kinase consensus sites fully activates extracellular signal-regulated kinase 1/2 in human embryonic kidney 293 cells: lack of evidence for G (s)/G (i) switching. Mol. Pharmacol. 62, 1094-1102.
22. Gerhardt, C. C. and van Heerikhuizen, H. (1997). Functional characteristics of heterologously expressed 5-HT receptors. Eur. J. Pharmacol. 334, 1-23.
23. Gerhardt, C. C., Leysen, J. E., Planta, R. J., Vreugdenhil, E. and van Heerikhuizen, H. (1996). Functional characterization of a 5-HT2 receptor cDNA cloned from Lymnaea stagnalis. Eur. J. Pharmacol. 311, 249-258.
24. Gether, U. (2000). Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr. Rev. 21, 90-113.
25. Hamdan, F. F., Ungrin, M. D., Abramovitz, M. and Ribeiro, P. (1999). Characterization of a novel serotonin receptor from Caenorhabditis elegans: cloning and expression of two splice variants. J. Neurochem. 72, 1372-1383.
26. Hobson, R. J., Geng, J., Gray, A. D. and Komuniecki, R. W. (2003). SER-7b, a constitutively active Galphas coupled 5-HT7-like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron. J. Neurochem. 87, 22-29.
27. Hooper, S. L. and DiCaprio, R. A. (2004). Crustacean motor pattern generator networks. Neurosignals 13, 50-69.
28. Hoyer, D., Hannon, J. P. and Martin, G. R. (2002). Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol. Biochem. Behav. 71, 533-554.
29. Huber, R., Smith, K., Delago, A., Isaksson, K. and Kravitz, E. A. (1997). Serotonin and aggressive motivation in crustaceans: altering the decision to retreat. Proc. Natl. Acad. Sci. USA 94, 5939-5942.
30. Johnston, C. A. and Watts, V. J. (2003). Sensitization of adenylate cyclase: a general mechanism of neuroadaptation to persistent activation of Galpha (i/o)-coupled receptors? Life Sci. 73, 2913-2925.
31. Kandel, E. R. and Schwartz, J. H. (1982). Molecular biology of learning: modulation of transmitter release. Science 218, 433-443.
32. Katz, P. S. and Tazaki, K. (1992). Comparative and evolutionary aspects of the crustacean stomatogastric system. In Dynamic Biological Networks: The Stomatogastric Nervous System (ed. R. M. Harris-Warrick, E. Marder, A. I. Selverston and M. Moulins), pp. 221-261. Cambridge, MA: MIT.
33. Kravitz, E. A. (2000). Serotonin and aggression: insights gained from a lobster model system and speculations on the role of amine neurons in a complex behavior. J. Comp. Physiol. A 186, 221-238.
34. Kristiansen, K. (2004). Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function. Pharmacol. Ther. 103, 21-80.
35. Kristiansen, K., Kroeze, W. K., Willins, D. L., Gelber, E. I., Savage, J. E., Glennon, R. A. and Roth, B. L. (2000). A highly conserved aspartic acid (Asp-155) anchors the terminal amine moiety of tryptamines and is involved in membrane targeting of the 5-HT (2A) serotonin receptor but does not participate in activation via a "salt-bridge disruption" mechanism. J. Pharmacol. Exp. Ther. 293, 735-746.
36. Kroeze, W. K., Kristiansen, K. and Roth, B. L. (2002). Molecular biology of serotonin receptors structure and function at the molecular level. Curr. Top. Med. Chem. 2, 507-528.
37. Lanctot, P. M., Leclerc, P. C., Escher, E., Guillemette, G. and Leduc, R. (2006). Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor. Biochem. Biophys. Res. Commun. 340, 395-402.
38. Lee, C. Y., Yau, S. M., Liau, C. S. and Huang, W. J. (2000). Serotonergic regulation of blood glucose levels in the crayfish, Procambarus clarkii: site of action and receptor characterization. J. Exp. Zool. 286, 596-605.
39. Li, X. C., Giot, J. F., Kuhl, D., Hen, R. and Kandel, E. R. (1995). Cloning and characterization of two related serotonergic receptors from the brain and the reproductive system of Aplysia that activate phospholipase C. J. Neurosci. 15, 7585-7591.
40. Liu, Y. F., Ghahremani, M. H., Rasenick, M. M., Jakobs, K. H. and Albert, P. R. (1999). Stimulation of cAMP synthesis by Gi-coupled receptors upon ablation of distinct Galphai protein expression. Gi subtype specificity of the 5-HT1A receptor. J. Biol. Chem. 274, 16444-16450.
41. May, L. T., Avlani, V. A., Sexton, P. M. and Christopoulos, A. (2004). Allosteric modulation of G protein-coupled receptors. Curr. Pharm. Des. 10, 2003-2013.
42. Olde, B. and McCombie, W. R. (1997). Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans. J. Mol. Neurosci. 8, 53-62.
43. Roth, B. L., Shoham, M., Choudhary, M. S. and Khan, N. (1997). Identification of conserved aromatic residues essential for agonist binding and second messenger production at 5-hydroxytryptamine2A receptors. Mol. Pharmacol. 52, 259-266.
44. Saudou, F., Boschert, U., Amlaiky, N., Plassat, J. L. and Hen, R. (1992). A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. EMBO J. 11, 7-17.
45. Shapiro, D. A., Kristiansen, K., Weiner, D. M., Kroeze, W. K. and Roth, B. L. (2002). Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6. J. Biol. Chem. 277, 11441-11449.
46. Silberstein, S. D. (1998). Methysergide. Cephalalgia 18, 421-435.
47. Sosa, M. A., Spitzer, N., Edwards, D. H. and Baro, D. J. (2004). A crustacean serotonin receptor: cloning and distribution in the thoracic ganglia of crayfish and freshwater prawn. J. Comp. Neurol. 473, 526-537.
48. Spitzer, N., Antonsen, B. L. and Edwards, D. H. (2005). Immunocytochemical mapping and quantification of expression of a putative type 1 serotonin receptor in the crayfish nervous system. J. Comp. Neurol. 484, 261-282.
49. Sprouse, J., Reynolds, L., Li, X., Braselton, J. and Schmidt, A. (2004). 8-OH-DPAT as a 5-HT7 agonist: phase shifts of the circadian biological clock through increases in cAMP production. Neuropharmacology 46, 52-62.
50. Strader, C. D., Fong, T. M., Graziano, M. P. and Tota, M. R. (1995). The family of G-protein-coupled receptors. FASEB J. 9, 745-754.
51. Strawn, J. R., Neckameyer, W. S. and Cooper, R. L. (2000). The effects of 5-HT on sensory, central and motor neurons driving the abdominal superficial flexor muscles in the crayfish. Comp. Biochem. Physiol. 127B, 533-550.
52. Sugamori, K. S., Sunahara, R. K., Guan, H. C., Bulloch, A. G. M., Tensen, C. P., Seeman, P., Niznik, H. B. and Van Tol, H. H. M. (1993). Serotonin receptor cDNA cloned from Lymnaea stagnalis. Proc. Natl. Acad. Sci. USA 90, 11-15.
53. Teshiba, T., Shamsian, A., Yashar, B., Yeh, S. R., Edwards, D. H. and Krasne, F. B. (2001). Dual and opposing modulatory effects of serotonin on crayfish lateral giant escape command neurons. J. Neurosci. 21, 4523-4529.
54. Tierney, A. J. (2001). Structure and function of invertebrate 5-HT receptors: a review. Comp. Biochem. Physiol. 128A, 791-804.
55. Tierney, A. J. and Mangiamele, L. A. (2001). Effects of serotonin and serotonin analogs on posture and agonistic behavior in crayfish. J. Comp. Physiol. A 187, 757-767.
56. Tierney, A. J., Greenlaw, M. A., Dams-O'Connor, K., Aig, S. D. and Perna, A. M. (2004). Behavioral effects of serotonin and serotonin agonists in two crayfish species, Procambarus clarkii and Orconectes rusticus. Comp. Biochem. Physiol. 139A, 495-502.
57. Witz, P., Amlaiky, N., Plassat, J. L., Maroteaux, L., Borrelli, E. and Hen, R. (1990). Cloning and characterization of a Drosophila serotonin receptor that activates adenylate cyclase. Proc. Natl. Acad. Sci. USA 87, 8940-8944.
58. Yeh, S. R., Fricke, R. A. and Edwards, D. H. (1996). The effect of social experience on serotonergic modulation of the escape circuit of crayfish. Science 271, 366-369.
59. Yeh, S.-R., Musolf, B. E. and Edwards, D. H. (1997). Neuronal adaptations to changes in the social dominance status of crayfish. J. Neurosci. 17, 697-708.
60. Zhang, B. and Harris-Warrick, R. M. (1994). Multiple receptors mediate the modulatory effects of serotonergic neurons in a small neural network. J. Exp. Biol. 190, 55-77.