-
1
-
-
0142106351
-
Novel functions and signalling pathways for GDNF
-
Sariola H., and Saarma M. Novel functions and signalling pathways for GDNF. J Cell Sci 116 (2003) 3855-3862
-
(2003)
J Cell Sci
, vol.116
, pp. 3855-3862
-
-
Sariola, H.1
Saarma, M.2
-
2
-
-
0028795044
-
Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain
-
Beck K., Valverde J., Alexi T., Poulsen K., Moffat B., Vandlen R., et al. Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373 (1995) 339-341
-
(1995)
Nature
, vol.373
, pp. 339-341
-
-
Beck, K.1
Valverde, J.2
Alexi, T.3
Poulsen, K.4
Moffat, B.5
Vandlen, R.6
-
3
-
-
0028109526
-
Glial cell line-derived neurotrophic factor reverses toxin- induced injury to midbrain dopaminergic neurons in vivo
-
Hoffer B., Hoffman A., Bowenkamp K., Huettl P., Hudson J., Martin D., et al. Glial cell line-derived neurotrophic factor reverses toxin- induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 182 (1994) 107-111
-
(1994)
Neurosci Lett
, vol.182
, pp. 107-111
-
-
Hoffer, B.1
Hoffman, A.2
Bowenkamp, K.3
Huettl, P.4
Hudson, J.5
Martin, D.6
-
4
-
-
0030774588
-
GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis
-
Kearns C., Cass W., Smoot K., Kryscio R., and Gash D. GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis. J Neurosci 17 (1997) 7111-7118
-
(1997)
J Neurosci
, vol.17
, pp. 7111-7118
-
-
Kearns, C.1
Cass, W.2
Smoot, K.3
Kryscio, R.4
Gash, D.5
-
5
-
-
0031840772
-
Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line- derived neurotrophic factor against 6-hydroxydopamine in vivo
-
Sullivan A., Opacka-Juffry J., and Blunt S. Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line- derived neurotrophic factor against 6-hydroxydopamine in vivo. Eur J Neurosci 10 (1998) 57-63
-
(1998)
Eur J Neurosci
, vol.10
, pp. 57-63
-
-
Sullivan, A.1
Opacka-Juffry, J.2
Blunt, S.3
-
6
-
-
0028834063
-
Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
-
Tomac A., Lindqvist E., Lin L., Ogren S., Young D., Hoffer B., et al. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373 (1995) 335-339
-
(1995)
Nature
, vol.373
, pp. 335-339
-
-
Tomac, A.1
Lindqvist, E.2
Lin, L.3
Ogren, S.4
Young, D.5
Hoffer, B.6
-
7
-
-
0030593912
-
Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats
-
Martin D., Miller G., Cullen T., Fischer N., Dix D., and Russell D. Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats. Eur J Pharmacol 317 (1996) 247-256
-
(1996)
Eur J Pharmacol
, vol.317
, pp. 247-256
-
-
Martin, D.1
Miller, G.2
Cullen, T.3
Fischer, N.4
Dix, D.5
Russell, D.6
-
8
-
-
0029934782
-
Glial cell line-derived neurotrophic factor: the lateral cerebral ventricle as a site of administration for stimulation of the substantia nigra dopamine system in rats
-
Martin D., Miller G., Fischer N., Diz D., Cullen T., and Russell D. Glial cell line-derived neurotrophic factor: the lateral cerebral ventricle as a site of administration for stimulation of the substantia nigra dopamine system in rats. Eur J Neurosci 8 (1996) 1249-1255
-
(1996)
Eur J Neurosci
, vol.8
, pp. 1249-1255
-
-
Martin, D.1
Miller, G.2
Fischer, N.3
Diz, D.4
Cullen, T.5
Russell, D.6
-
9
-
-
17744408450
-
Intracerebroventricular glial cell line-derived neurotrophic factor improves motor function and supports nigrostriatal dopamine neurons in bilaterally 6-hydroxydopamine lesioned rats
-
Bowenkamp K., Lapchak P., Hoffer B., Miller P., and Bickford P. Intracerebroventricular glial cell line-derived neurotrophic factor improves motor function and supports nigrostriatal dopamine neurons in bilaterally 6-hydroxydopamine lesioned rats. Exp Neurol 145 (1997) 104-117
-
(1997)
Exp Neurol
, vol.145
, pp. 104-117
-
-
Bowenkamp, K.1
Lapchak, P.2
Hoffer, B.3
Miller, P.4
Bickford, P.5
-
10
-
-
0033773237
-
Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
-
Kirik D., Rosenblad C., and Bjorklund A. Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor. Eur J Neurosci 12 (2000) 3871-3882
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3871-3882
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
-
11
-
-
0034526219
-
Single or continuous injection of glial cell line-derived neurotrophic factor in the striatum induces recovery of the nigrostriatal dopaminergic system
-
Aoi M., Date I., Tomita S., and Ohmoto T. Single or continuous injection of glial cell line-derived neurotrophic factor in the striatum induces recovery of the nigrostriatal dopaminergic system. Neurol Res. 22 (2000) 832-836
-
(2000)
Neurol Res.
, vol.22
, pp. 832-836
-
-
Aoi, M.1
Date, I.2
Tomita, S.3
Ohmoto, T.4
-
12
-
-
0033948750
-
GDNF induces recovery of the nigrostriatal dopaminergic system in the rat brain following intracerebroventricular or intraparenchymal administration
-
Aoi M., Date I., Tomita S., and Ohmoto T. GDNF induces recovery of the nigrostriatal dopaminergic system in the rat brain following intracerebroventricular or intraparenchymal administration. Acta Neurochir 142 (2000) 805-810
-
(2000)
Acta Neurochir
, vol.142
, pp. 805-810
-
-
Aoi, M.1
Date, I.2
Tomita, S.3
Ohmoto, T.4
-
13
-
-
13344277993
-
Functional recovery in parkinsonian monkeys treated with GDNF
-
Gash D., Zhang Z., Ovadia A., Cass W., Yi A., Simmerman L., et al. Functional recovery in parkinsonian monkeys treated with GDNF. Nature 380 (1996) 252-255
-
(1996)
Nature
, vol.380
, pp. 252-255
-
-
Gash, D.1
Zhang, Z.2
Ovadia, A.3
Cass, W.4
Yi, A.5
Simmerman, L.6
-
14
-
-
0030838127
-
Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys
-
Miyoshi Y., Zhang Z., Ovadia A., Lapchak P., Collins F., Hilt D., et al. Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys. Ann Neurol 42 (1997) 208-214
-
(1997)
Ann Neurol
, vol.42
, pp. 208-214
-
-
Miyoshi, Y.1
Zhang, Z.2
Ovadia, A.3
Lapchak, P.4
Collins, F.5
Hilt, D.6
-
15
-
-
0030967428
-
Dose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys
-
Zhang Z., Miyoshi Y., Lapchak P., Collins F., Hilt D., Lebel C., et al. Dose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys. J Pharmacol Exp Ther 282 (1997) 1396-1401
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 1396-1401
-
-
Zhang, Z.1
Miyoshi, Y.2
Lapchak, P.3
Collins, F.4
Hilt, D.5
Lebel, C.6
-
16
-
-
0033616388
-
GDNF improves dopamine function in the substantia nigra but not the putamen of unilateral MPTP-lesioned rhesus monkeys
-
Gerhardt G., Cass W., Huettl P., Brock S., Zhang Z., and Gash D. GDNF improves dopamine function in the substantia nigra but not the putamen of unilateral MPTP-lesioned rhesus monkeys. Brain Res 817 (1999) 163-171
-
(1999)
Brain Res
, vol.817
, pp. 163-171
-
-
Gerhardt, G.1
Cass, W.2
Huettl, P.3
Brock, S.4
Zhang, Z.5
Gash, D.6
-
17
-
-
0035910367
-
Glial cell line-derived neurotrophic factor concentration dependently improves disability and motor activity in MPTP-treated common marmosets
-
Costa S., Iravani M., Pearce R., and Jenner P. Glial cell line-derived neurotrophic factor concentration dependently improves disability and motor activity in MPTP-treated common marmosets. Eur J Pharmacol 412 (2001) 45-50
-
(2001)
Eur J Pharmacol
, vol.412
, pp. 45-50
-
-
Costa, S.1
Iravani, M.2
Pearce, R.3
Jenner, P.4
-
18
-
-
0036787532
-
Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
-
Grondin R., Zhang Z., Yi A., Cass W., Maswood N., Andersen A., et al. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 125 (2002) 2191-2201
-
(2002)
Brain
, vol.125
, pp. 2191-2201
-
-
Grondin, R.1
Zhang, Z.2
Yi, A.3
Cass, W.4
Maswood, N.5
Andersen, A.6
-
19
-
-
0032850453
-
Clinicopathological findings following intraventricular glial- derived neurotrophic factor treatment in a patient with Parkinson's disease
-
Kordower J., Palfi S., Chen E., Ma S., Sendera T., Cochran E., et al. Clinicopathological findings following intraventricular glial- derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann Neurol 46 (1999) 419-424
-
(1999)
Ann Neurol
, vol.46
, pp. 419-424
-
-
Kordower, J.1
Palfi, S.2
Chen, E.3
Ma, S.4
Sendera, T.5
Cochran, E.6
-
20
-
-
0037435511
-
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
-
Nutt J., Burchiel K., Comella C., Jankovic J., Lang A., Laws Jr. E., et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 60 (2003) 69-73
-
(2003)
Neurology
, vol.60
, pp. 69-73
-
-
Nutt, J.1
Burchiel, K.2
Comella, C.3
Jankovic, J.4
Lang, A.5
Laws Jr., E.6
-
21
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill S., Patel N., Hotton G., O'Sullivan K., McCarter R., Bunnage M., et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 9 (2003) 589-595
-
(2003)
Nat Med
, vol.9
, pp. 589-595
-
-
Gill, S.1
Patel, N.2
Hotton, G.3
O'Sullivan, K.4
McCarter, R.5
Bunnage, M.6
-
22
-
-
13144282676
-
Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study
-
Patel N., Bunnage M., Plaha P., Svendsen C., Heywood P., and Gill S. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann Neurol 57 (2005) 298-302
-
(2005)
Ann Neurol
, vol.57
, pp. 298-302
-
-
Patel, N.1
Bunnage, M.2
Plaha, P.3
Svendsen, C.4
Heywood, P.5
Gill, S.6
-
23
-
-
14844311296
-
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
-
Slevin J., Gerhardt G., Smith C., Gash D., Kryscio R., and Young B. Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 102 (2005) 216-222
-
(2005)
J Neurosurg
, vol.102
, pp. 216-222
-
-
Slevin, J.1
Gerhardt, G.2
Smith, C.3
Gash, D.4
Kryscio, R.5
Young, B.6
-
24
-
-
32544447701
-
GDNF in treatment of Parkinson's disease: response to editorial
-
Lang A., Langston J., Stoessl A., Brodsky M., Brooks D., Dhawan V., et al. GDNF in treatment of Parkinson's disease: response to editorial. Lancet Neurol 5 (2006) 200-202
-
(2006)
Lancet Neurol
, vol.5
, pp. 200-202
-
-
Lang, A.1
Langston, J.2
Stoessl, A.3
Brodsky, M.4
Brooks, D.5
Dhawan, V.6
-
25
-
-
34047220707
-
Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal
-
Slevin J., Gash D., Smith C., Gerhardt G., Kryscio R., Chebrolu H., et al. Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal. J Neurosurg 106 (2007) 614-620
-
(2007)
J Neurosurg
, vol.106
, pp. 614-620
-
-
Slevin, J.1
Gash, D.2
Smith, C.3
Gerhardt, G.4
Kryscio, R.5
Chebrolu, H.6
-
26
-
-
0028917168
-
Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and parkinsonian symptoms
-
Lindner M., Winn S., Baetge E., Hammang J., Gentile F., Doherty E., et al. Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and parkinsonian symptoms. Exp Neurol 132 (1995) 62-76
-
(1995)
Exp Neurol
, vol.132
, pp. 62-76
-
-
Lindner, M.1
Winn, S.2
Baetge, E.3
Hammang, J.4
Gentile, F.5
Doherty, E.6
-
27
-
-
0034874180
-
Grafting of encapsulated genetically modified cells secreting GDNF into the striatum of parkinsonian model rats
-
Date I., Shingo T., Yoshida H., Fujiwara K., Kobayashi K., Takeuchi A., et al. Grafting of encapsulated genetically modified cells secreting GDNF into the striatum of parkinsonian model rats. Cell Transplant 10 (2001) 397-401
-
(2001)
Cell Transplant
, vol.10
, pp. 397-401
-
-
Date, I.1
Shingo, T.2
Yoshida, H.3
Fujiwara, K.4
Kobayashi, K.5
Takeuchi, A.6
-
28
-
-
0037106156
-
Neuroprotective and restorative effects of intrastriatal grafting of encapsulated GDNF- producing cells in a rat model of Parkinson's disease
-
Shingo T., Date I., Yoshida H., and Ohmoto T. Neuroprotective and restorative effects of intrastriatal grafting of encapsulated GDNF- producing cells in a rat model of Parkinson's disease. J Neurosci Res 69 (2002) 946-954
-
(2002)
J Neurosci Res
, vol.69
, pp. 946-954
-
-
Shingo, T.1
Date, I.2
Yoshida, H.3
Ohmoto, T.4
-
29
-
-
13844280470
-
Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease
-
Yasuhara T., Shingo T., Muraoka K., Kobayashi K., Takeuchi A., Yano A., et al. Early transplantation of an encapsulated glial cell line-derived neurotrophic factor-producing cell demonstrating strong neuroprotective effects in a rat model of Parkinson disease. J Neurosurg 102 (2005) 80-89
-
(2005)
J Neurosurg
, vol.102
, pp. 80-89
-
-
Yasuhara, T.1
Shingo, T.2
Muraoka, K.3
Kobayashi, K.4
Takeuchi, A.5
Yano, A.6
-
30
-
-
15044349743
-
Long-term restoration of nigrostriatal system function by implanting GDNF genetically modified fibroblasts in a rat model of Parkinson's disease
-
Duan D., Yang H., Zhang J., Zhang J., and Xu Q. Long-term restoration of nigrostriatal system function by implanting GDNF genetically modified fibroblasts in a rat model of Parkinson's disease. Exp Brain Res 161 (2005) 316-324
-
(2005)
Exp Brain Res
, vol.161
, pp. 316-324
-
-
Duan, D.1
Yang, H.2
Zhang, J.3
Zhang, J.4
Xu, Q.5
-
31
-
-
29144536727
-
Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease
-
Ericson C., Georgievska B., and Lundberg C. Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease. Eur J Neurosci 22 (2005) 2755-2764
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2755-2764
-
-
Ericson, C.1
Georgievska, B.2
Lundberg, C.3
-
32
-
-
0036144928
-
Ex vivo and in vitro studies of transgene expression in rat astrocytes transduced with lentiviral vectors
-
Ericson C., Wictorin K., and Lundberg C. Ex vivo and in vitro studies of transgene expression in rat astrocytes transduced with lentiviral vectors. Exp Neurol 173 (2002) 22-30
-
(2002)
Exp Neurol
, vol.173
, pp. 22-30
-
-
Ericson, C.1
Wictorin, K.2
Lundberg, C.3
-
33
-
-
0035887595
-
Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease
-
Akerud P., Canals J., Snyder E., and Arenas E. Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. J Neurosci 21 (2001) 8108-8118
-
(2001)
J Neurosci
, vol.21
, pp. 8108-8118
-
-
Akerud, P.1
Canals, J.2
Snyder, E.3
Arenas, E.4
-
34
-
-
33645140627
-
Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates
-
Behrstock S., Ebert A., McHugh J., Vosberg S., Moore J., Schneider B., et al. Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Ther 13 (2006) 379-388
-
(2006)
Gene Ther
, vol.13
, pp. 379-388
-
-
Behrstock, S.1
Ebert, A.2
McHugh, J.3
Vosberg, S.4
Moore, J.5
Schneider, B.6
-
35
-
-
33845258753
-
Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease
-
Yasuhara T., Matsukawa N., Hara K., Yu G., Xu L., Maki M., et al. Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. J Neurosci 26 (2006) 12497-12511
-
(2006)
J Neurosci
, vol.26
, pp. 12497-12511
-
-
Yasuhara, T.1
Matsukawa, N.2
Hara, K.3
Yu, G.4
Xu, L.5
Maki, M.6
-
36
-
-
15244343198
-
Transplantation of fetal kidney cells: neuroprotection and neuroregeneration
-
Chiang Y., Borlongan C., Zhou F., Hoffer B., and Wang Y. Transplantation of fetal kidney cells: neuroprotection and neuroregeneration. Cell Transplant 14 (2005) 1-9
-
(2005)
Cell Transplant
, vol.14
, pp. 1-9
-
-
Chiang, Y.1
Borlongan, C.2
Zhou, F.3
Hoffer, B.4
Wang, Y.5
-
37
-
-
0034895752
-
Protection of nigral neurons by GDNF-engineered marrow cell transplantation
-
Park K., Eglitis M., and Mouradian M. Protection of nigral neurons by GDNF-engineered marrow cell transplantation. Neurosci Res 40 (2001) 315-323
-
(2001)
Neurosci Res
, vol.40
, pp. 315-323
-
-
Park, K.1
Eglitis, M.2
Mouradian, M.3
-
38
-
-
0035894875
-
Functional regeneration in a rat Parkinson's model after intrastriatal grafts of glial cell line-derived neurotrophic factor and transforming growth factor beta1-expressing extra- adrenal chromaffin cells of the Zuckerkandl's organ
-
Espejo E., Gonzalez-Albo M., Moraes J., El Banoua F., Flores J., and Caraballo I. Functional regeneration in a rat Parkinson's model after intrastriatal grafts of glial cell line-derived neurotrophic factor and transforming growth factor beta1-expressing extra- adrenal chromaffin cells of the Zuckerkandl's organ. J Neurosci 21 (2001) 9888-9895
-
(2001)
J Neurosci
, vol.21
, pp. 9888-9895
-
-
Espejo, E.1
Gonzalez-Albo, M.2
Moraes, J.3
El Banoua, F.4
Flores, J.5
Caraballo, I.6
-
39
-
-
34548151842
-
Cell-replacement and gene- therapy strategies for Parkinson's and Alzheimer's disease
-
Korecka J., Verhaagen J., and Hol E. Cell-replacement and gene- therapy strategies for Parkinson's and Alzheimer's disease. Regen Med 2 (2007) 425-446
-
(2007)
Regen Med
, vol.2
, pp. 425-446
-
-
Korecka, J.1
Verhaagen, J.2
Hol, E.3
-
40
-
-
33750470830
-
Cell therapy for Parkinson's disease: only young onset patients allowed?. Reflections about the results of recent clinical trials with cell therapy and the progression of Parkinson's disease
-
Linazasoro G. Cell therapy for Parkinson's disease: only young onset patients allowed?. Reflections about the results of recent clinical trials with cell therapy and the progression of Parkinson's disease. Cell Transplant 15 (2006) 463-473
-
(2006)
Cell Transplant
, vol.15
, pp. 463-473
-
-
Linazasoro, G.1
-
41
-
-
0030795798
-
Intrastriatal injection of an adenoviral vector expressing glial- cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
-
Bilang-Bleuel A., Revah F., Colin P., Locquet I., Robert J., Mallet J., et al. Intrastriatal injection of an adenoviral vector expressing glial- cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc Natl Acad Sci USA 94 (1997) 8818-8823
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8818-8823
-
-
Bilang-Bleuel, A.1
Revah, F.2
Colin, P.3
Locquet, I.4
Robert, J.5
Mallet, J.6
-
42
-
-
0031019795
-
Dopaminergic neurons protected from degeneration by GDNF gene therapy
-
Choi-Lundberg D., Lin Q., Chang Y., Chiang Y., Hay C., Mohajeri H., et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 275 (1997) 838-841
-
(1997)
Science
, vol.275
, pp. 838-841
-
-
Choi-Lundberg, D.1
Lin, Q.2
Chang, Y.3
Chiang, Y.4
Hay, C.5
Mohajeri, H.6
-
43
-
-
0031577599
-
Adenovirus-mediated transduction with human glial cell line-derived neurotrophic factor gene prevents 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-induced dopamine depletion in striatum of mouse brain
-
Kojima H., Abiru Y., Sakajiri K., Watabe K., Ohishi N., Takamori M., et al. Adenovirus-mediated transduction with human glial cell line-derived neurotrophic factor gene prevents 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-induced dopamine depletion in striatum of mouse brain. Biochem Biophys Res Com. 238 (1997) 569-573
-
(1997)
Biochem Biophys Res Com.
, vol.238
, pp. 569-573
-
-
Kojima, H.1
Abiru, Y.2
Sakajiri, K.3
Watabe, K.4
Ohishi, N.5
Takamori, M.6
-
44
-
-
0031589698
-
Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease
-
Lapchak P., Araujo D., Hilt D., Sheng J., and Jiao S. Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease. Brain Res 777 (1997) 153-160
-
(1997)
Brain Res
, vol.777
, pp. 153-160
-
-
Lapchak, P.1
Araujo, D.2
Hilt, D.3
Sheng, J.4
Jiao, S.5
-
45
-
-
0031456051
-
Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line- derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats
-
Mandel R., Spratt S., Snyder R., and Leff S. Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line- derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc Natl Acad Sci USA 94 (1997) 14083-14088
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14083-14088
-
-
Mandel, R.1
Spratt, S.2
Snyder, R.3
Leff, S.4
-
46
-
-
0034659835
-
Long-term rAAV- mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
-
Kirik D., Rosenblad C., Bjorklund A., and Mandel R. Long-term rAAV- mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system. J Neurosci 20 (2000) 4686-4700
-
(2000)
J Neurosci
, vol.20
, pp. 4686-4700
-
-
Kirik, D.1
Rosenblad, C.2
Bjorklund, A.3
Mandel, R.4
-
47
-
-
0035998720
-
Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion
-
McGrath J., Lintz E., Hoffer B., Gerhardt G., Quintero E., and Granholm A. Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion. Cell Transplant 11 (2002) 215-227
-
(2002)
Cell Transplant
, vol.11
, pp. 215-227
-
-
McGrath, J.1
Lintz, E.2
Hoffer, B.3
Gerhardt, G.4
Quintero, E.5
Granholm, A.6
-
48
-
-
85047698430
-
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease
-
Wang L., Muramatsu S., Lu Y., Ikeguchi K., Fujimoto K., Okada T., et al. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease. Gene Ther 9 (2002) 381-389
-
(2002)
Gene Ther
, vol.9
, pp. 381-389
-
-
Wang, L.1
Muramatsu, S.2
Lu, Y.3
Ikeguchi, K.4
Fujimoto, K.5
Okada, T.6
-
49
-
-
4644350860
-
HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity
-
Monville C., Torres E., Thomas E., Scarpini C., Muhith J., Lewis J., et al. HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity. Brain Res 1024 (2004) 1-15
-
(2004)
Brain Res
, vol.1024
, pp. 1-15
-
-
Monville, C.1
Torres, E.2
Thomas, E.3
Scarpini, C.4
Muhith, J.5
Lewis, J.6
-
50
-
-
0343517507
-
Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF
-
Bensadoun J., Deglon N., Tseng J., Ridet J., Zurn A., and Aebischer P. Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF. Exp Neurol 164 (2000) 15-24
-
(2000)
Exp Neurol
, vol.164
, pp. 15-24
-
-
Bensadoun, J.1
Deglon, N.2
Tseng, J.3
Ridet, J.4
Zurn, A.5
Aebischer, P.6
-
51
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower J., Emborg M., Bloch J., Ma S., Chu Y., Leventhal L., et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290 (2000) 767-773
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.1
Emborg, M.2
Bloch, J.3
Ma, S.4
Chu, Y.5
Leventhal, L.6
-
52
-
-
0037096359
-
Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration
-
Palfi S., Leventhal L., Chu Y., Ma S., Emborg M., Bakay R., et al. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration. J Neurosci 22 (2002) 4942-4954
-
(2002)
J Neurosci
, vol.22
, pp. 4942-4954
-
-
Palfi, S.1
Leventhal, L.2
Chu, Y.3
Ma, S.4
Emborg, M.5
Bakay, R.6
-
53
-
-
0037148074
-
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector
-
Georgievska B., Kirik D., Rosenblad C., Lundberg C., and Bjorklund A. Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector. Neuroreport 13 (2002) 75-82
-
(2002)
Neuroreport
, vol.13
, pp. 75-82
-
-
Georgievska, B.1
Kirik, D.2
Rosenblad, C.3
Lundberg, C.4
Bjorklund, A.5
-
54
-
-
28744446884
-
Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
-
Dowd E., Monville C., Torres E., Wong L., Azzouz M., Mazarakis N., et al. Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model. Eur J Neurosci 22 (2005) 2587-2595
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2587-2595
-
-
Dowd, E.1
Monville, C.2
Torres, E.3
Wong, L.4
Azzouz, M.5
Mazarakis, N.6
-
55
-
-
34547838170
-
The first steps towards gene therapy for Parkinson's disease
-
Svendsen C. The first steps towards gene therapy for Parkinson's disease. Lancet Neurol 6 (2007) 754-756
-
(2007)
Lancet Neurol
, vol.6
, pp. 754-756
-
-
Svendsen, C.1
-
56
-
-
0029827559
-
Neurturin, a relative of glial-cell-line-derived neurotrophic factor
-
Kotzbauer P., Lampe P., Heuckeroth R., Golden J., Creedon D., Johnson Jr. E., et al. Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 384 (1996) 467-470
-
(1996)
Nature
, vol.384
, pp. 467-470
-
-
Kotzbauer, P.1
Lampe, P.2
Heuckeroth, R.3
Golden, J.4
Creedon, D.5
Johnson Jr., E.6
-
57
-
-
0030917158
-
Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons
-
Creedon D., Tansey M., Baloh R., Osborne P., Lampe P., Fahrner T., et al. Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proc Natl Acad Sci USA 94 (1997) 7018-7023
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7018-7023
-
-
Creedon, D.1
Tansey, M.2
Baloh, R.3
Osborne, P.4
Lampe, P.5
Fahrner, T.6
-
58
-
-
0032125462
-
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons
-
Horger B., Nishimura M., Armanini M., Wang L., Poulsen K., Rosenblad C., et al. Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons. J Neurosci 18 (1998) 4929-4937
-
(1998)
J Neurosci
, vol.18
, pp. 4929-4937
-
-
Horger, B.1
Nishimura, M.2
Armanini, M.3
Wang, L.4
Poulsen, K.5
Rosenblad, C.6
-
59
-
-
0032939002
-
Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle
-
Rosenblad C., Kirik D., Devaux B., Moffat B., Phillips H., and Bjorklund A. Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the lateral ventricle. Eur J Neurosci 11 (1999) 1554-1566
-
(1999)
Eur J Neurosci
, vol.11
, pp. 1554-1566
-
-
Rosenblad, C.1
Kirik, D.2
Devaux, B.3
Moffat, B.4
Phillips, H.5
Bjorklund, A.6
-
60
-
-
0033038785
-
Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons
-
Akerud P., Alberch J., Eketjall S., Wagner J., and Arenas E. Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. J Neurochem 73 (1999) 70-78
-
(1999)
J Neurochem
, vol.73
, pp. 70-78
-
-
Akerud, P.1
Alberch, J.2
Eketjall, S.3
Wagner, J.4
Arenas, E.5
-
61
-
-
0037199818
-
Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease
-
Oiwa Y., Yoshimura R., Nakai K., and Itakura T. Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease. Brain Res 947 (2002) 271-283
-
(2002)
Brain Res
, vol.947
, pp. 271-283
-
-
Oiwa, Y.1
Yoshimura, R.2
Nakai, K.3
Itakura, T.4
-
62
-
-
33847254416
-
Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson's disease
-
Liu W., Lu G., Li B., and Chen S. Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson's disease. Parkinsonism Relat Disord 13 (2007) 77-88
-
(2007)
Parkinsonism Relat Disord
, vol.13
, pp. 77-88
-
-
Liu, W.1
Lu, G.2
Li, B.3
Chen, S.4
-
63
-
-
33947127571
-
Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease
-
Ye M., Wang X., Zhang Y., Lu G., Liang L., Xu J., et al. Transplantation of bone marrow stromal cells containing the neurturin gene in rat model of Parkinson's disease. Brain Res 1142 (2007) 206-216
-
(2007)
Brain Res
, vol.1142
, pp. 206-216
-
-
Ye, M.1
Wang, X.2
Zhang, Y.3
Lu, G.4
Liang, L.5
Xu, J.6
-
64
-
-
23644452944
-
Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct
-
Fjord-Larsen L., Johansen J., Kusk P., Tornoe J., Gronborg M., Rosenblad C., et al. Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct. Exp Neurol 195 (2005) 49-60
-
(2005)
Exp Neurol
, vol.195
, pp. 49-60
-
-
Fjord-Larsen, L.1
Johansen, J.2
Kusk, P.3
Tornoe, J.4
Gronborg, M.5
Rosenblad, C.6
-
65
-
-
33846011117
-
Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease
-
Gasmi M., Herzog C., Brandon E., Cunningham J., Ramirez G., Ketchum E., et al. Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease. Mol Ther 15 (2007) 62-68
-
(2007)
Mol Ther
, vol.15
, pp. 62-68
-
-
Gasmi, M.1
Herzog, C.2
Brandon, E.3
Cunningham, J.4
Ramirez, G.5
Ketchum, E.6
-
66
-
-
33845993229
-
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
-
Kordower J., Herzog C., Dass B., Bakay R., Stansell III J., Gasmi M., et al. Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 60 (2006) 706-715
-
(2006)
Ann Neurol
, vol.60
, pp. 706-715
-
-
Kordower, J.1
Herzog, C.2
Dass, B.3
Bakay, R.4
Stansell III, J.5
Gasmi, M.6
-
67
-
-
34447572589
-
Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys
-
Herzog C., Dass B., Holden J., Stansell III J., Gasmi M., Tuszynski M., et al. Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys. Mov Disord 22 (2007) 1124-1132
-
(2007)
Mov Disord
, vol.22
, pp. 1124-1132
-
-
Herzog, C.1
Dass, B.2
Holden, J.3
Stansell III, J.4
Gasmi, M.5
Tuszynski, M.6
-
68
-
-
34250336916
-
AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE- 120 for Parkinson's disease
-
Gasmi M., Brandon E., Herzog C., Wilson A., Bishop K., Hofer E., et al. AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE- 120 for Parkinson's disease. Neurobiol Dis 27 (2007) 67-76
-
(2007)
Neurobiol Dis
, vol.27
, pp. 67-76
-
-
Gasmi, M.1
Brandon, E.2
Herzog, C.3
Wilson, A.4
Bishop, K.5
Hofer, E.6
-
69
-
-
34447130809
-
Second chance
-
Check E. Second chance. Nat Med 13 (2007) 770-771
-
(2007)
Nat Med
, vol.13
, pp. 770-771
-
-
Check, E.1
-
70
-
-
0029082799
-
Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons
-
Lein P., Johnson M., Guo X., Rueger D., and Higgins D. Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons. Neuron 15 (1995) 597-605
-
(1995)
Neuron
, vol.15
, pp. 597-605
-
-
Lein, P.1
Johnson, M.2
Guo, X.3
Rueger, D.4
Higgins, D.5
-
71
-
-
0035044683
-
Bone morphogenetic proteins (BMP6 and BMP7) enhance the protective effect of neurotrophins on cultured septal cholinergic neurons during hypoglycemia
-
Nonner D., Barrett E., Kaplan P., and Barrett J. Bone morphogenetic proteins (BMP6 and BMP7) enhance the protective effect of neurotrophins on cultured septal cholinergic neurons during hypoglycemia. J Neurochem 77 (2001) 691-699
-
(2001)
J Neurochem
, vol.77
, pp. 691-699
-
-
Nonner, D.1
Barrett, E.2
Kaplan, P.3
Barrett, J.4
-
72
-
-
0036894545
-
Glia induce dendritic growth in cultured sympathetic neurons by modulating the balance between bone morphogenetic proteins (BMPs) and BMP antagonists
-
Lein P., Beck H., Chandrasekaran V., Gallagher P., Chen H., Lin Y., et al. Glia induce dendritic growth in cultured sympathetic neurons by modulating the balance between bone morphogenetic proteins (BMPs) and BMP antagonists. J Neurosci 22 (2002) 10377-10387
-
(2002)
J Neurosci
, vol.22
, pp. 10377-10387
-
-
Lein, P.1
Beck, H.2
Chandrasekaran, V.3
Gallagher, P.4
Chen, H.5
Lin, Y.6
-
73
-
-
34948900289
-
Dual effect of adenovirus-mediated transfer of BMP7 in mixed neuron-glial cultures: Neuroprotection and cellular differentiation
-
Tsai M., Weng C., Shyue S., Liou D., Chen C., Chiu C., et al. Dual effect of adenovirus-mediated transfer of BMP7 in mixed neuron-glial cultures: Neuroprotection and cellular differentiation. J Neurosci Res 85 (2007) 2950-2959
-
(2007)
J Neurosci Res
, vol.85
, pp. 2950-2959
-
-
Tsai, M.1
Weng, C.2
Shyue, S.3
Liou, D.4
Chen, C.5
Chiu, C.6
-
74
-
-
0030875989
-
Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells
-
Jordan J., Bottner M., Schluesener H., Unsicker K., and Krieglstein K. Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. Eur J Neurosci 9 (1997) 1699-1709
-
(1997)
Eur J Neurosci
, vol.9
, pp. 1699-1709
-
-
Jordan, J.1
Bottner, M.2
Schluesener, H.3
Unsicker, K.4
Krieglstein, K.5
-
75
-
-
0344443258
-
Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals
-
Chen H., Lein P., Wang J., Gash D., Hoffer B., and Chiang Y. Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals. Brain Res 994 (2003) 81-90
-
(2003)
Brain Res
, vol.994
, pp. 81-90
-
-
Chen, H.1
Lein, P.2
Wang, J.3
Gash, D.4
Hoffer, B.5
Chiang, Y.6
-
76
-
-
0029831732
-
Expression of serine/threonine kinase receptors including the bone morphogenetic factor type II receptor in the developing and adult rat brain
-
Soderstrom S., Bengtsson H., and Ebendal T. Expression of serine/threonine kinase receptors including the bone morphogenetic factor type II receptor in the developing and adult rat brain. Cell Tissue Res 286 (1996) 269-279
-
(1996)
Cell Tissue Res
, vol.286
, pp. 269-279
-
-
Soderstrom, S.1
Bengtsson, H.2
Ebendal, T.3
-
77
-
-
4444279516
-
Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson's disease
-
Harvey B., Mark A., Chou J., Chen G., Hoffer B., and Wang Y. Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson's disease. Brain Res 1022 (2004) 88-95
-
(2004)
Brain Res
, vol.1022
, pp. 88-95
-
-
Harvey, B.1
Mark, A.2
Chou, J.3
Chen, G.4
Hoffer, B.5
Wang, Y.6
-
78
-
-
0033159598
-
Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites
-
Cook S. Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites. Orthopedics 22 (1999) 669-671
-
(1999)
Orthopedics
, vol.22
, pp. 669-671
-
-
Cook, S.1
-
79
-
-
0035222452
-
Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions
-
Friedlaender G., Perry C., Cole J., Cook S., Cierny G., Muschler G., et al. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am 83-A Suppl 1 (2001) S151-S158
-
(2001)
J Bone Joint Surg Am
, vol.83 -A
, Issue.SUPPL. 1
-
-
Friedlaender, G.1
Perry, C.2
Cole, J.3
Cook, S.4
Cierny, G.5
Muschler, G.6
-
80
-
-
29444440588
-
Comparison of OP-1 Putty (rhBMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis: a minimum 2-year follow-up pilot study
-
Vaccaro A., Anderson D., Patel T., Fischgrund J., Truumees E., Herkowitz H., et al. Comparison of OP-1 Putty (rhBMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis: a minimum 2-year follow-up pilot study. Spine 30 (2005) 2709-2716
-
(2005)
Spine
, vol.30
, pp. 2709-2716
-
-
Vaccaro, A.1
Anderson, D.2
Patel, T.3
Fischgrund, J.4
Truumees, E.5
Herkowitz, H.6
-
81
-
-
33645290271
-
Osteogenic protein-1 (BMP-7) accelerates healing of scaphoid non-union with proximal pole sclerosis
-
Bilic R., Simic P., Jelic M., Stern-Padovan R., Dodig D., van Meerdervoort H., et al. Osteogenic protein-1 (BMP-7) accelerates healing of scaphoid non-union with proximal pole sclerosis. Int Orthop 30 (2006) 128-134
-
(2006)
Int Orthop
, vol.30
, pp. 128-134
-
-
Bilic, R.1
Simic, P.2
Jelic, M.3
Stern-Padovan, R.4
Dodig, D.5
van Meerdervoort, H.6
-
82
-
-
33646573974
-
A prospective randomized study of posterolateral lumbar fusion using osteogenic protein-1 (OP-1) versus local autograft with ceramic bone substitute: emphasis of surgical exploration and histologic assessment
-
Kanayama M., Hashimoto T., Shigenobu K., Yamane S., Bauer T., and Togawa D. A prospective randomized study of posterolateral lumbar fusion using osteogenic protein-1 (OP-1) versus local autograft with ceramic bone substitute: emphasis of surgical exploration and histologic assessment. Spine 31 (2006) 1067-1074
-
(2006)
Spine
, vol.31
, pp. 1067-1074
-
-
Kanayama, M.1
Hashimoto, T.2
Shigenobu, K.3
Yamane, S.4
Bauer, T.5
Togawa, D.6
-
83
-
-
34548804505
-
Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer
-
Buijs J., Henriquez N., van Overveld P., van der Horst G., Que I., Schwaninger R., et al. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res 67 (2007) 8742-8751
-
(2007)
Cancer Res
, vol.67
, pp. 8742-8751
-
-
Buijs, J.1
Henriquez, N.2
van Overveld, P.3
van der Horst, G.4
Que, I.5
Schwaninger, R.6
-
84
-
-
33947229511
-
RhBMP-7 accelerates the healing in distal tibial fractures treated by external fixation
-
Ristiniemi J., Flinkkila T., Hyvonen P., Lakovaara M., Pakarinen H., and Jalovaara P. RhBMP-7 accelerates the healing in distal tibial fractures treated by external fixation. J Bone Joint Surg 89 (2007) 265-272
-
(2007)
J Bone Joint Surg
, vol.89
, pp. 265-272
-
-
Ristiniemi, J.1
Flinkkila, T.2
Hyvonen, P.3
Lakovaara, M.4
Pakarinen, H.5
Jalovaara, P.6
-
85
-
-
27744503046
-
Clinical applications of BMP-7: the UK perspective
-
Giannoudis P., and Tzioupis C. Clinical applications of BMP-7: the UK perspective. Injury 36 Suppl 3 (2005) S47-S50
-
(2005)
Injury
, vol.36
, Issue.SUPPL. 3
-
-
Giannoudis, P.1
Tzioupis, C.2
-
86
-
-
0024451643
-
Molecular cloning and expression of brain- derived neurotrophic factor
-
Leibrock J., Lottspeich F., Hohn A., Hofer M., Hengerer B., Masiakowski P., et al. Molecular cloning and expression of brain- derived neurotrophic factor. Nature 341 (1989) 149-152
-
(1989)
Nature
, vol.341
, pp. 149-152
-
-
Leibrock, J.1
Lottspeich, F.2
Hohn, A.3
Hofer, M.4
Hengerer, B.5
Masiakowski, P.6
-
87
-
-
20144370557
-
Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease
-
Liu Q., Walther D., Drgon T., Polesskaya O., Lesnick T., Strain K., et al. Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. Am J Med Genet B Neuropsychiatr Genet 134 (2005) 93-103
-
(2005)
Am J Med Genet B Neuropsychiatr Genet
, vol.134
, pp. 93-103
-
-
Liu, Q.1
Walther, D.2
Drgon, T.3
Polesskaya, O.4
Lesnick, T.5
Strain, K.6
-
88
-
-
0035075348
-
BDNF enhances retinal ganglion cell survival in cats with optic nerve damage
-
Chen H., and Weber A. BDNF enhances retinal ganglion cell survival in cats with optic nerve damage. Invest Ophthalmol Vis Sci 42 (2001) 966-974
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 966-974
-
-
Chen, H.1
Weber, A.2
-
89
-
-
30744439794
-
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
-
Coull J., Beggs S., Boudreau D., Boivin D., Tsuda M., Inoue K., et al. BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature 438 (2005) 1017-1021
-
(2005)
Nature
, vol.438
, pp. 1017-1021
-
-
Coull, J.1
Beggs, S.2
Boudreau, D.3
Boivin, D.4
Tsuda, M.5
Inoue, K.6
-
90
-
-
17244377058
-
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor
-
Li Y., Jia Y., Cui K., Li N., Zheng Z., Wang Y., et al. Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature 434 (2005) 894-898
-
(2005)
Nature
, vol.434
, pp. 894-898
-
-
Li, Y.1
Jia, Y.2
Cui, K.3
Li, N.4
Zheng, Z.5
Wang, Y.6
-
91
-
-
34248155631
-
The role of neurotrophins in axonal growth, guidance, and regeneration
-
Lykissas M., Batistatou A., Charalabopoulos K., and Beris A. The role of neurotrophins in axonal growth, guidance, and regeneration. Curr Neurovasc Res 4 (2007) 143-151
-
(2007)
Curr Neurovasc Res
, vol.4
, pp. 143-151
-
-
Lykissas, M.1
Batistatou, A.2
Charalabopoulos, K.3
Beris, A.4
-
92
-
-
0035799569
-
BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization
-
Guillin O., Diaz J., Carroll P., Griffon N., Schwartz J., and Sokoloff P. BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization. Nature 411 (2001) 86-89
-
(2001)
Nature
, vol.411
, pp. 86-89
-
-
Guillin, O.1
Diaz, J.2
Carroll, P.3
Griffon, N.4
Schwartz, J.5
Sokoloff, P.6
-
93
-
-
0033597983
-
Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease
-
Mogi M., Togari A., Kondo T., Mizuno Y., Komure O., Kuno S., et al. Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci Lett 270 (1999) 45-48
-
(1999)
Neurosci Lett
, vol.270
, pp. 45-48
-
-
Mogi, M.1
Togari, A.2
Kondo, T.3
Mizuno, Y.4
Komure, O.5
Kuno, S.6
-
94
-
-
0033602009
-
Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra
-
Parain K., Murer M., Yan Q., Faucheux B., Agid Y., Hirsch E., et al. Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra. Neuroreport 10 (1999) 557-561
-
(1999)
Neuroreport
, vol.10
, pp. 557-561
-
-
Parain, K.1
Murer, M.2
Yan, Q.3
Faucheux, B.4
Agid, Y.5
Hirsch, E.6
-
95
-
-
33745000075
-
Repeated L-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease
-
Zhang X., Andren P., and Svenningsson P. Repeated L-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease. Brain Res 1095 (2006) 207-210
-
(2006)
Brain Res
, vol.1095
, pp. 207-210
-
-
Zhang, X.1
Andren, P.2
Svenningsson, P.3
-
96
-
-
0029134980
-
Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease
-
Yoshimoto Y., Lin Q., Collier T., Frim D., Breakefield X., and Bohn M. Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson's disease. Brain Res 691 (1995) 25-36
-
(1995)
Brain Res
, vol.691
, pp. 25-36
-
-
Yoshimoto, Y.1
Lin, Q.2
Collier, T.3
Frim, D.4
Breakefield, X.5
Bohn, M.6
-
97
-
-
0029610630
-
Intrastriatal implantation of fibroblasts genetically engineered to produce brain- derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease
-
Levivier M., Przedborski S., Bencsics C., and Kang U. Intrastriatal implantation of fibroblasts genetically engineered to produce brain- derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. J Neurosci 15 (1995) 7810-7820
-
(1995)
J Neurosci
, vol.15
, pp. 7810-7820
-
-
Levivier, M.1
Przedborski, S.2
Bencsics, C.3
Kang, U.4
-
98
-
-
0028276809
-
Implanted fibroblasts genetically engineered to produce brain- derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat
-
Frim D., Uhler T., Galpern W., Beal M., Breakefield X., and Isacson O. Implanted fibroblasts genetically engineered to produce brain- derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc Natl Acad Sci USA 91 (1994) 5104-5108
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5104-5108
-
-
Frim, D.1
Uhler, T.2
Galpern, W.3
Beal, M.4
Breakefield, X.5
Isacson, O.6
-
99
-
-
0029978443
-
Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration
-
Galpern W., Frim D., Tatter S., Altar C., Beal M., and Isacson O. Cell-mediated delivery of brain-derived neurotrophic factor enhances dopamine levels in an MPP+ rat model of substantia nigra degeneration. Cell Transplant 5 (1996) 225-232
-
(1996)
Cell Transplant
, vol.5
, pp. 225-232
-
-
Galpern, W.1
Frim, D.2
Tatter, S.3
Altar, C.4
Beal, M.5
Isacson, O.6
-
100
-
-
0032704605
-
Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer
-
Klein R., Lewis M., Muzyczka N., and Meyer E. Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer. Brain Res 847 (1999) 314-320
-
(1999)
Brain Res
, vol.847
, pp. 314-320
-
-
Klein, R.1
Lewis, M.2
Muzyczka, N.3
Meyer, E.4
-
101
-
-
23644437308
-
Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease
-
Sun M., Kong L., Wang X., Lu X., Gao Q., and Geller A. Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. Brain Res 1052 (2005) 119-129
-
(2005)
Brain Res
, vol.1052
, pp. 119-129
-
-
Sun, M.1
Kong, L.2
Wang, X.3
Lu, X.4
Gao, Q.5
Geller, A.6
-
102
-
-
0027532456
-
BDNF and trkB mRNA expression in the rat hippocampus following entorhinal cortex lesions
-
Lapchak P., Araujo D., and Hefti F. BDNF and trkB mRNA expression in the rat hippocampus following entorhinal cortex lesions. Neuroreport 4 (1993) 191-194
-
(1993)
Neuroreport
, vol.4
, pp. 191-194
-
-
Lapchak, P.1
Araujo, D.2
Hefti, F.3
-
103
-
-
0033997315
-
Identification of potential compounds promoting BDNF production in nigral dopaminergic neurons: clinical implication in Parkinson's disease
-
Chun H., Son J., and Son J. Identification of potential compounds promoting BDNF production in nigral dopaminergic neurons: clinical implication in Parkinson's disease. Neuroreport 11 (2000) 511-514
-
(2000)
Neuroreport
, vol.11
, pp. 511-514
-
-
Chun, H.1
Son, J.2
Son, J.3
-
104
-
-
6944242126
-
Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members
-
Weinreb O., Bar-Am O., Amit T., Chillag-Talmor O., and Youdim M. Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members. FASEB J 18 (2004) 1471-1473
-
(2004)
FASEB J
, vol.18
, pp. 1471-1473
-
-
Weinreb, O.1
Bar-Am, O.2
Amit, T.3
Chillag-Talmor, O.4
Youdim, M.5
-
105
-
-
33751078859
-
Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism
-
Sagi Y., Mandel S., Amit T., and Youdim M. Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism. Neurobiol Dis 25 (2007) 35-44
-
(2007)
Neurobiol Dis
, vol.25
, pp. 35-44
-
-
Sagi, Y.1
Mandel, S.2
Amit, T.3
Youdim, M.4
-
106
-
-
0037942718
-
MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons
-
Petrova P., Raibekas A., Pevsner J., Vigo N., Anafi M., Moore M., et al. MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci 20 (2003) 173-188
-
(2003)
J Mol Neurosci
, vol.20
, pp. 173-188
-
-
Petrova, P.1
Raibekas, A.2
Pevsner, J.3
Vigo, N.4
Anafi, M.5
Moore, M.6
-
107
-
-
33644509266
-
Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release
-
Zhou C., Xiao C., Commissiong J., Krnjevic K., and Ye J. Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release. Neuroreport 17 (2006) 293-297
-
(2006)
Neuroreport
, vol.17
, pp. 293-297
-
-
Zhou, C.1
Xiao, C.2
Commissiong, J.3
Krnjevic, K.4
Ye, J.5
-
108
-
-
34447132381
-
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
-
Lindholm P., Voutilainen M., Lauren J., Peranen J., Leppanen V., Andressoo J., et al. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature 448 (2007) 73-77
-
(2007)
Nature
, vol.448
, pp. 73-77
-
-
Lindholm, P.1
Voutilainen, M.2
Lauren, J.3
Peranen, J.4
Leppanen, V.5
Andressoo, J.6
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