메뉴 건너뛰기




Volumn 253, Issue 2, 1999, Pages 533-540

Activated Rac1 selectively up-regulates the expression of integrin α6β4 and induces cell adhesion and membrane ruffles of nonadherent colon cancer Colo201 cells

Author keywords

Cdc42; Cell adhesion; Human colon cancer cells; Integrin 6 4; Rac1

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CELL CYCLE PROTEIN; COLLAGEN; ENZYME INHIBITOR; FIBRONECTIN; GUANOSINE TRIPHOSPHATASE; INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

EID: 0033572701     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1999.4720     Document Type: Article
Times cited : (15)

References (33)
  • 1
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes R. O. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell. 69:1992;11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 2
    • 0343002567 scopus 로고    scopus 로고
    • Common principles in cell adhesion
    • Ruoslahti E., Obrink B. Common principles in cell adhesion. Exp. Cell Res. 159:1996;263-273.
    • (1996) Exp. Cell Res. , vol.159 , pp. 263-273
    • Ruoslahti, E.1    Obrink, B.2
  • 3
    • 0032030656 scopus 로고    scopus 로고
    • Integrins and GTPases in tumour cell growth, motility and invasion
    • Keely P., Parise L., Juliano R. Integrins and GTPases in tumour cell growth, motility and invasion. Trends Cell Biol. 8:1998;101-106.
    • (1998) Trends Cell Biol. , vol.8 , pp. 101-106
    • Keely, P.1    Parise, L.2    Juliano, R.3
  • 5
    • 0031459917 scopus 로고    scopus 로고
    • Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
    • Keely P. J., Westwick J. K., Whitehead I. P., Der C. J., Parise L. V. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature. 390:1997;632-636.
    • (1997) Nature , vol.390 , pp. 632-636
    • Keely, P.J.1    Westwick, J.K.2    Whitehead, I.P.3    Der, C.J.4    Parise, L.V.5
  • 6
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes C. D., Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell. 81:1995;53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 7
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley A. J., Paterson H. F., Johnston C. F., Diekmann D., Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell. 70:1992;401-410.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.F.3    Diekmann, D.4    Hall, A.5
  • 8
    • 0029562867 scopus 로고
    • The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases
    • Hotchin N. A., Hall A. The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases. J. Cell Biol. 131:1995;1857-1865.
    • (1995) J. Cell Biol. , vol.131 , pp. 1857-1865
    • Hotchin, N.A.1    Hall, A.2
  • 9
    • 0030940218 scopus 로고    scopus 로고
    • Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages
    • Allen W. E., Jones G. E., Pollard J. W., Ridley A. J. Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J. Cell Sci. 110:1997;707-720.
    • (1997) J. Cell Sci. , vol.110 , pp. 707-720
    • Allen, W.E.1    Jones, G.E.2    Pollard, J.W.3    Ridley, A.J.4
  • 10
    • 0030059222 scopus 로고    scopus 로고
    • Role of Rho in chemoattractant-activated leukocyte adhesion through integrins
    • Laudanna C., Campbell J. J., Butcher E. C. Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science. 271:1996;981-983.
    • (1996) Science , vol.271 , pp. 981-983
    • Laudanna, C.1    Campbell, J.J.2    Butcher, E.C.3
  • 11
  • 13
    • 0031456065 scopus 로고    scopus 로고
    • Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion
    • Shaw L. M., Rabinovitz I., Wang H. H.-F., Toker A., Mercurio A. M. Activation of phosphoinositide 3-OH kinase by the α6β4 integrin promotes carcinoma invasion. Cell. 26:1997;949-960.
    • (1997) Cell , vol.26 , pp. 949-960
    • Shaw, L.M.1    Rabinovitz, I.2    Wang, H.H.-F.3    Toker, A.4    Mercurio, A.M.5
  • 14
    • 0000602007 scopus 로고    scopus 로고
    • Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation
    • Nakagawa K., Sogo S., Hioki K., Tokunaga R., Taketani S. Acquisition of cell adhesion and induction of focal adhesion kinase of human colon cancer Colo 201 cells by retinoic acid-induced differentiation. Differentiation. 62:1998;249-257.
    • (1998) Differentiation , vol.62 , pp. 249-257
    • Nakagawa, K.1    Sogo, S.2    Hioki, K.3    Tokunaga, R.4    Taketani, S.5
  • 15
    • 0032426222 scopus 로고    scopus 로고
    • Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A
    • Mohri T., Kameshita I., Suzuki S., Hioki K., Tokunaga R., Takatani S. Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. Cell Struct. Funct. 23:1998;255-264.
    • (1998) Cell Struct. Funct. , vol.23 , pp. 255-264
    • Mohri, T.1    Kameshita, I.2    Suzuki, S.3    Hioki, K.4    Tokunaga, R.5    Takatani, S.6
  • 18
    • 0032553305 scopus 로고    scopus 로고
    • Molecular characterization of a newly identified heme-binding protein induced during differentiation of murine erythroleukemia cells
    • Taketani S., Adachi Y., Kohno H., Ikehara S., Tokunaga R., Ishii T. Molecular characterization of a newly identified heme-binding protein induced during differentiation of murine erythroleukemia cells. J. Biol. Chem. 273:1998;31388-31394.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31388-31394
    • Taketani, S.1    Adachi, Y.2    Kohno, H.3    Ikehara, S.4    Tokunaga, R.5    Ishii, T.6
  • 19
    • 0032572557 scopus 로고    scopus 로고
    • Integrin-mediated signals regulated by members of the rho family of GTPases
    • Clark E. A., King W. G., Brugge J. S., Symons M., Hynes R. O. Integrin-mediated signals regulated by members of the rho family of GTPases. J. Cell Biol. 142:1998;573-586.
    • (1998) J. Cell Biol. , vol.142 , pp. 573-586
    • Clark, E.A.1    King, W.G.2    Brugge, J.S.3    Symons, M.4    Hynes, R.O.5
  • 20
    • 0031844821 scopus 로고    scopus 로고
    • Activation of Rac and Cdc42 by integrins mediates cell spreading
    • Price L. S., Leng J., Schwartz M. A., Bokoch G. M. Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol. Biol. Cell. 9:1998;1863-1871.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1863-1871
    • Price, L.S.1    Leng, J.2    Schwartz, M.A.3    Bokoch, G.M.4
  • 21
    • 0031806711 scopus 로고    scopus 로고
    • Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes
    • D'Souza-Schorey C., Boettner B., van Aelst L. Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes. Mol. Cell. Biol. 18:1998;3936-3942.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3936-3942
    • D'Souza-Schorey, C.1    Boettner, B.2    Van Aelst, L.3
  • 22
    • 0030684003 scopus 로고    scopus 로고
    • Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes
    • Cox D., Chang P., Zhang Q., Reddy P. G., Bokoch G. M., Greenberg S. Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes. J. Exp. Med. 186:1997;1487-1494.
    • (1997) J. Exp. Med. , vol.186 , pp. 1487-1494
    • Cox, D.1    Chang, P.2    Zhang, Q.3    Reddy, P.G.4    Bokoch, G.M.5    Greenberg, S.6
  • 23
    • 0029789678 scopus 로고    scopus 로고
    • The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton
    • Leung T., Chen X. Q., Manser E., Lim L. The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton. Mol. Cell. Biol. 16:1996;5313-5327.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5313-5327
    • Leung, T.1    Chen, X.Q.2    Manser, E.3    Lim, L.4
  • 24
    • 0025864486 scopus 로고
    • Expression and endocytosis of integrin VLA receptors for collagen, fibronectin and laminin by normal human keratinocytes
    • Le Varlet B., Staquet M. J., Dezutler-Dambayant C., Gaucherand M., Schmitt D. Expression and endocytosis of integrin VLA receptors for collagen, fibronectin and laminin by normal human keratinocytes. J. Dermatol. Sci. 2:1991;287-299.
    • (1991) J. Dermatol. Sci. , vol.2 , pp. 287-299
    • Le Varlet, B.1    Staquet, M.J.2    Dezutler-Dambayant, C.3    Gaucherand, M.4    Schmitt, D.5
  • 25
    • 0030587460 scopus 로고    scopus 로고
    • The beta 4 integrin subunit is expressed in mouse fibroblasts and modulated by transforming growth factor β1
    • Scardigli R., Soddu S., Falcioni R., Crescenzi M., Cimino L., Sacchi A. The beta 4 integrin subunit is expressed in mouse fibroblasts and modulated by transforming growth factor β1. Exp. Cell Res. 227:1996;223-229.
    • (1996) Exp. Cell Res. , vol.227 , pp. 223-229
    • Scardigli, R.1    Soddu, S.2    Falcioni, R.3    Crescenzi, M.4    Cimino, L.5    Sacchi, A.6
  • 27
    • 0029661897 scopus 로고    scopus 로고
    • A function for the integrin α6β4 in the invasive properties of colorectal carcinoma cells
    • Chao C., Lotz M. M., Clarke A. C., Mercurio A. M. A function for the integrin α6β4 in the invasive properties of colorectal carcinoma cells. Cancer Res. 56:1996;4811-4819.
    • (1996) Cancer Res. , vol.56 , pp. 4811-4819
    • Chao, C.1    Lotz, M.M.2    Clarke, A.C.3    Mercurio, A.M.4
  • 28
    • 0029946652 scopus 로고    scopus 로고
    • Regulation of leukocyte integrin function: Affinity vs. avidity
    • Stewart M., Hogg N. Regulation of leukocyte integrin function: Affinity vs. avidity. J. Cell. Biochem. 61:1996;554-561.
    • (1996) J. Cell. Biochem. , vol.61 , pp. 554-561
    • Stewart, M.1    Hogg, N.2
  • 29
    • 0030872850 scopus 로고    scopus 로고
    • Adhesive interactions in the immune system
    • Brown E. J. Adhesive interactions in the immune system. Trends Cell Biol. 7:1997;289-295.
    • (1997) Trends Cell Biol. , vol.7 , pp. 289-295
    • Brown, E.J.1
  • 30
    • 0026658606 scopus 로고
    • Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells
    • Pignatelli M., Liu D., Nasin M. N., Stamp V. H., Hirano S., Takeichi M. Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. Br. J. Cancer. 66:1992;629-634.
    • (1992) Br. J. Cancer , vol.66 , pp. 629-634
    • Pignatelli, M.1    Liu, D.2    Nasin, M.N.3    Stamp, V.H.4    Hirano, S.5    Takeichi, M.6
  • 31
    • 0031283128 scopus 로고    scopus 로고
    • The integrin α6β4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures
    • Rabinobitz I., Mercurio A. M. The integrin α6β4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J. Cell Biol. 139:1997;1873-1884.
    • (1997) J. Cell Biol. , vol.139 , pp. 1873-1884
    • Rabinobitz, I.1    Mercurio, A.M.2
  • 32
    • 0029666420 scopus 로고    scopus 로고
    • Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival
    • Dowling J., Yu O. C., Fuchs E. Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J. Cell Biol. 134:1996;559-572.
    • (1996) J. Cell Biol. , vol.134 , pp. 559-572
    • Dowling, J.1    Yu, O.C.2    Fuchs, E.3
  • 33


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.