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Volumn 131, Issue 2, 2008, Pages 260-270

A wide range of NS3/4A protease catalytic efficiencies in HCV-infected individuals

Author keywords

Catalytic efficiency; Genotype; HCV; NS3 protease

Indexed keywords

ADAPTOR PROTEIN; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; PROTEIN CARDIF; PROTEIN TRIF; PROTEINASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

EID: 38649125211     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2007.10.003     Document Type: Article
Times cited : (17)

References (66)
  • 1
    • 0028929431 scopus 로고
    • To C or not to C: these are the questions
    • Alter H.J. To C or not to C: these are the questions. Blood 85 7 (1995) 1681-1695
    • (1995) Blood , vol.85 , Issue.7 , pp. 1681-1695
    • Alter, H.J.1
  • 2
    • 33744507185 scopus 로고    scopus 로고
    • From structure to function: new insights into hepatitis C virus RNA replication
    • Appel N., Schaller T., Penin F., and Bartenschlager R. From structure to function: new insights into hepatitis C virus RNA replication. J. Biol. Chem. 281 15 (2006) 9833-9836
    • (2006) J. Biol. Chem. , vol.281 , Issue.15 , pp. 9833-9836
    • Appel, N.1    Schaller, T.2    Penin, F.3    Bartenschlager, R.4
  • 4
    • 0028241489 scopus 로고
    • Kinetic and structural-analyses of hepatitis-C virus polyprotein processing
    • Bartenschlager R., Ahlbornlaake L., Mous J., and Jacobsen H. Kinetic and structural-analyses of hepatitis-C virus polyprotein processing. J. Virol. 68 8 (1994) 5045-5055
    • (1994) J. Virol. , vol.68 , Issue.8 , pp. 5045-5055
    • Bartenschlager, R.1    Ahlbornlaake, L.2    Mous, J.3    Jacobsen, H.4
  • 6
    • 15244346528 scopus 로고    scopus 로고
    • Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKK epsilon
    • Breiman A., Grandvaux N., Lin R.T., Ottone C., Akira S., Yoneyama M., Fujita T., Hiscott J., and Meurs E.F. Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKK epsilon. J. Virol. 79 7 (2005) 3969-3978
    • (2005) J. Virol. , vol.79 , Issue.7 , pp. 3969-3978
    • Breiman, A.1    Grandvaux, N.2    Lin, R.T.3    Ottone, C.4    Akira, S.5    Yoneyama, M.6    Fujita, T.7    Hiscott, J.8    Meurs, E.F.9
  • 7
    • 0036384360 scopus 로고    scopus 로고
    • Catalytic efficiency and phenotype of HIV-1 proteases encoding single critical resistance substitutions
    • Cabana M., Fernandez G., Parera M., Clotet B., and Martinez M.A. Catalytic efficiency and phenotype of HIV-1 proteases encoding single critical resistance substitutions. Virology 300 1 (2002) 71-78
    • (2002) Virology , vol.300 , Issue.1 , pp. 71-78
    • Cabana, M.1    Fernandez, G.2    Parera, M.3    Clotet, B.4    Martinez, M.A.5
  • 9
    • 33744828747 scopus 로고    scopus 로고
    • Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms
    • Cheng G., Zhong J., and Chisari F.V. Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. USA 103 22 (2006) 8499-8504
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.22 , pp. 8499-8504
    • Cheng, G.1    Zhong, J.2    Chisari, F.V.3
  • 11
    • 0032422389 scopus 로고    scopus 로고
    • Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein
    • Dimasi N., Pasquo A., Martin F., Di Marco S., Steinkuhler C., Cortese R., and Sollazzo M. Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein. Protein Eng. 11 12 (1998) 1257-1265
    • (1998) Protein Eng. , vol.11 , Issue.12 , pp. 1257-1265
    • Dimasi, N.1    Pasquo, A.2    Martin, F.3    Di Marco, S.4    Steinkuhler, C.5    Cortese, R.6    Sollazzo, M.7
  • 12
    • 0028290579 scopus 로고
    • Both Ns3 and Ns4a are required for proteolytic processing of hepatitis-C virus nonstructural proteins
    • Failla C., Tomei L., and Defrancesco R. Both Ns3 and Ns4a are required for proteolytic processing of hepatitis-C virus nonstructural proteins. J. Virol. 68 6 (1994) 3753-3760
    • (1994) J. Virol. , vol.68 , Issue.6 , pp. 3753-3760
    • Failla, C.1    Tomei, L.2    Defrancesco, R.3
  • 13
    • 33847210305 scopus 로고    scopus 로고
    • Fitness landscape of human immunodeficiency virus type 1 protease quasispecies
    • Fernandez G., Clotet B., and Martinez M.A. Fitness landscape of human immunodeficiency virus type 1 protease quasispecies. J. Virol. 81 5 (2007) 2485-2496
    • (2007) J. Virol. , vol.81 , Issue.5 , pp. 2485-2496
    • Fernandez, G.1    Clotet, B.2    Martinez, M.A.3
  • 14
    • 20144379712 scopus 로고    scopus 로고
    • Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease
    • Ferreon J.C., Ferreon A.C., Li K., and Lemon S.M. Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease. J. Biol. Chem. 280 21 (2005) 20483-20492
    • (2005) J. Biol. Chem. , vol.280 , Issue.21 , pp. 20483-20492
    • Ferreon, J.C.1    Ferreon, A.C.2    Li, K.3    Lemon, S.M.4
  • 15
    • 0037687422 scopus 로고    scopus 로고
    • Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
    • Foy E., Li K., Wang C., Sumpter Jr. R., Ikeda M., Lemon S.M., and Gale Jr. M. Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science 300 5622 (2003) 1145-1148
    • (2003) Science , vol.300 , Issue.5622 , pp. 1145-1148
    • Foy, E.1    Li, K.2    Wang, C.3    Sumpter Jr., R.4    Ikeda, M.5    Lemon, S.M.6    Gale Jr., M.7
  • 16
    • 34247344418 scopus 로고    scopus 로고
    • Genetic and catalytic efficiency structure of an HCV protease quasispecies
    • Franco S., Parera M., Aparicio E., Clotet B., and Martinez M.A. Genetic and catalytic efficiency structure of an HCV protease quasispecies. Hepatology 45 4 (2007) 899-910
    • (2007) Hepatology , vol.45 , Issue.4 , pp. 899-910
    • Franco, S.1    Parera, M.2    Aparicio, E.3    Clotet, B.4    Martinez, M.A.5
  • 17
    • 33846002756 scopus 로고    scopus 로고
    • Complete nucleotide sequence of genotype 4 hepatitis C viruses isolated from patients co-infected with human immunodeficiency virus type 1
    • Franco S., Tural C., Clotet B., and Martinez M.A. Complete nucleotide sequence of genotype 4 hepatitis C viruses isolated from patients co-infected with human immunodeficiency virus type 1. Virus Res. 123 2 (2007) 161-169
    • (2007) Virus Res. , vol.123 , Issue.2 , pp. 161-169
    • Franco, S.1    Tural, C.2    Clotet, B.3    Martinez, M.A.4
  • 18
    • 24344442462 scopus 로고    scopus 로고
    • The therapeutic potential of NS3 protease inhibitors in HCV infection
    • Goudreau N., and Llinas-Brunet M. The therapeutic potential of NS3 protease inhibitors in HCV infection. Expert Opin. Investig. Drugs 14 9 (2005) 1129-1144
    • (2005) Expert Opin. Investig. Drugs , vol.14 , Issue.9 , pp. 1129-1144
    • Goudreau, N.1    Llinas-Brunet, M.2
  • 19
    • 0027163740 scopus 로고
    • Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
    • Hijikata M., Mizushima H., Akagi T., Mori S., Kakiuchi N., Kato N., Tanaka T., Kimura K., and Shimotohno K. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol. 67 8 (1993) 4665-4675
    • (1993) J. Virol. , vol.67 , Issue.8 , pp. 4665-4675
    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7    Kimura, K.8    Shimotohno, K.9
  • 20
    • 0035983243 scopus 로고    scopus 로고
    • Genetic diversity and response to IFN of the NS3 protease gene from clinical strains of the hepatitis C virus
    • Holland-Staley C.A., Kovari L.C., Golenberg E.M., Pobursky K.J., and Mayers D.L. Genetic diversity and response to IFN of the NS3 protease gene from clinical strains of the hepatitis C virus. Arch. Virol. 147 7 (2002) 1385-1406
    • (2002) Arch. Virol. , vol.147 , Issue.7 , pp. 1385-1406
    • Holland-Staley, C.A.1    Kovari, L.C.2    Golenberg, E.M.3    Pobursky, K.J.4    Mayers, D.L.5
  • 21
    • 33747092279 scopus 로고    scopus 로고
    • Recent development of therapeutics for chronic HCV infection
    • Huang Z., Murray M.G., and Secrist III J.A. Recent development of therapeutics for chronic HCV infection. Antiviral Res. 71 2-3 (2006) 351-362
    • (2006) Antiviral Res. , vol.71 , Issue.2-3 , pp. 351-362
    • Huang, Z.1    Murray, M.G.2    Secrist III, J.A.3
  • 22
    • 34249845169 scopus 로고    scopus 로고
    • Functional and therapeutic analysis of hepatitis C virus NS3{middle dot}4A protease control of antiviral immune defense
    • Johnson C.L., Owen D.M., and Gale Jr. M. Functional and therapeutic analysis of hepatitis C virus NS3{middle dot}4A protease control of antiviral immune defense. J. Biol. Chem. 282 14 (2007) 10792-10803
    • (2007) J. Biol. Chem. , vol.282 , Issue.14 , pp. 10792-10803
    • Johnson, C.L.1    Owen, D.M.2    Gale Jr., M.3
  • 27
    • 0029074519 scopus 로고
    • A central region in the hepatitis-C virus Ns4a protein allows formation of an active Ns3-Ns4a serine proteinase complex in vivo and in vitro
    • Lin C., Thomson J.A., and Rice C.M. A central region in the hepatitis-C virus Ns4a protein allows formation of an active Ns3-Ns4a serine proteinase complex in vivo and in vitro. J. Virol. 69 7 (1995) 4373-4380
    • (1995) J. Virol. , vol.69 , Issue.7 , pp. 4373-4380
    • Lin, C.1    Thomson, J.A.2    Rice, C.M.3
  • 28
    • 33646446894 scopus 로고    scopus 로고
    • VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells
    • Lin K., Perni R.B., Kwong A.D., and Lin C. VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells. Antimicrob. Agents Chemother. 50 5 (2006) 1813-1822
    • (2006) Antimicrob. Agents Chemother. , vol.50 , Issue.5 , pp. 1813-1822
    • Lin, K.1    Perni, R.B.2    Kwong, A.D.3    Lin, C.4
  • 31
    • 0035157218 scopus 로고    scopus 로고
    • Mutations in hepatitis C virus RNAs conferring cell culture adaptation
    • Lohmann V., Korner F., Dobierzewska A., and Bartenschlager R. Mutations in hepatitis C virus RNAs conferring cell culture adaptation. J. Virol. 75 3 (2001) 1437-1449
    • (2001) J. Virol. , vol.75 , Issue.3 , pp. 1437-1449
    • Lohmann, V.1    Korner, F.2    Dobierzewska, A.3    Bartenschlager, R.4
  • 32
    • 0345188811 scopus 로고    scopus 로고
    • Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
    • Lohmann V., Korner F., Koch J., Herian U., Theilmann L., and Bartenschlager R. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285 5424 (1999) 110-113
    • (1999) Science , vol.285 , Issue.5424 , pp. 110-113
    • Lohmann, V.1    Korner, F.2    Koch, J.3    Herian, U.4    Theilmann, L.5    Bartenschlager, R.6
  • 34
    • 33747452685 scopus 로고    scopus 로고
    • Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
    • Lorenz I.C., Marcotrigiano J., Dentzer T.G., and Rice C.M. Structure of the catalytic domain of the hepatitis C virus NS2-3 protease. Nature 442 7104 (2006) 831-835
    • (2006) Nature , vol.442 , Issue.7104 , pp. 831-835
    • Lorenz, I.C.1    Marcotrigiano, J.2    Dentzer, T.G.3    Rice, C.M.4
  • 37
    • 0034007774 scopus 로고    scopus 로고
    • A bacteriophage lambda-based genetic screen for characterization of the activity and phenotype of the human immunodeficiency virus type 1 protease
    • Martinez M.A., Cabana M., Parera M., Gutierrez A., Este J.A., and Clotet B. A bacteriophage lambda-based genetic screen for characterization of the activity and phenotype of the human immunodeficiency virus type 1 protease. Antimicrob. Agents Chemother. 44 5 (2000) 1132-1139
    • (2000) Antimicrob. Agents Chemother. , vol.44 , Issue.5 , pp. 1132-1139
    • Martinez, M.A.1    Cabana, M.2    Parera, M.3    Gutierrez, A.4    Este, J.A.5    Clotet, B.6
  • 38
    • 0038673317 scopus 로고    scopus 로고
    • Genetic screen for monitoring hepatitis C virus NS3 serine protease activity
    • Martinez M.A., and Clotet B. Genetic screen for monitoring hepatitis C virus NS3 serine protease activity. Antimicrob. Agents Chemother. 47 5 (2003) 1760-1765
    • (2003) Antimicrob. Agents Chemother. , vol.47 , Issue.5 , pp. 1760-1765
    • Martinez, M.A.1    Clotet, B.2
  • 39
    • 27144440476 scopus 로고    scopus 로고
    • Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
    • Meylan E., Curran J., Hofmann K., Moradpour D., Binder M., Bartenschlager R., and Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437 7062 (2005) 1167-1172
    • (2005) Nature , vol.437 , Issue.7062 , pp. 1167-1172
    • Meylan, E.1    Curran, J.2    Hofmann, K.3    Moradpour, D.4    Binder, M.5    Bartenschlager, R.6    Tschopp, J.7
  • 41
    • 10044247531 scopus 로고    scopus 로고
    • Genetic screen for monitoring severe acute respiratory syndrome coronavirus 3C-like protease
    • Parera M., Clotet B., and Martinez M.A. Genetic screen for monitoring severe acute respiratory syndrome coronavirus 3C-like protease. J. Virol. 78 24 (2004) 14057-14061
    • (2004) J. Virol. , vol.78 , Issue.24 , pp. 14057-14061
    • Parera, M.1    Clotet, B.2    Martinez, M.A.3
  • 42
    • 33846829804 scopus 로고    scopus 로고
    • HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions
    • Parera M., Fernandez G., Clotet B., and Martinez M.A. HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions. Mol. Biol. Evol. 24 2 (2007) 382-387
    • (2007) Mol. Biol. Evol. , vol.24 , Issue.2 , pp. 382-387
    • Parera, M.1    Fernandez, G.2    Clotet, B.3    Martinez, M.A.4
  • 43
    • 30644457351 scopus 로고    scopus 로고
    • Hepatitis C virus population dynamics during infection
    • Pawlotsky J.M. Hepatitis C virus population dynamics during infection. Curr. Top. Microbiol. Immunol. 299 (2006) 261-284
    • (2006) Curr. Top. Microbiol. Immunol. , vol.299 , pp. 261-284
    • Pawlotsky, J.M.1
  • 46
    • 29744468807 scopus 로고    scopus 로고
    • Effect of bottlenecking on evolution of the nonstructural protein 3 gene of hepatitis C virus during sexually transmitted acute resolving infection
    • Quer J., Esteban J.I., Cos J., Sauleda S., Ocana L., Martell M., Otero T., Cubero M., Palou E., Murillo P., Esteban R., and Guardia J. Effect of bottlenecking on evolution of the nonstructural protein 3 gene of hepatitis C virus during sexually transmitted acute resolving infection. J. Virol. 79 24 (2005) 15131-15141
    • (2005) J. Virol. , vol.79 , Issue.24 , pp. 15131-15141
    • Quer, J.1    Esteban, J.I.2    Cos, J.3    Sauleda, S.4    Ocana, L.5    Martell, M.6    Otero, T.7    Cubero, M.8    Palou, E.9    Murillo, P.10    Esteban, R.11    Guardia, J.12
  • 47
    • 0029059334 scopus 로고
    • Hepatitis C virus-encoded NS2-3 protease: cleavage-site mutagenesis and requirements for bimolecular cleavage
    • Reed K.E., Grakoui A., and Rice C.M. Hepatitis C virus-encoded NS2-3 protease: cleavage-site mutagenesis and requirements for bimolecular cleavage. J. Virol. 69 7 (1995) 4127-4136
    • (1995) J. Virol. , vol.69 , Issue.7 , pp. 4127-4136
    • Reed, K.E.1    Grakoui, A.2    Rice, C.M.3
  • 51
    • 27744536474 scopus 로고    scopus 로고
    • Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection
    • Sarrazin C., Mihm U., Herrmann E., Welsch C., Albrecht M., Sarrazin U., Traver S., Lengauer T., and Zeuzem S. Clinical significance of in vitro replication-enhancing mutations of the hepatitis C virus (HCV) replicon in patients with chronic HCV infection. J. Infect. Dis. 192 10 (2005) 1710-1719
    • (2005) J. Infect. Dis. , vol.192 , Issue.10 , pp. 1710-1719
    • Sarrazin, C.1    Mihm, U.2    Herrmann, E.3    Welsch, C.4    Albrecht, M.5    Sarrazin, U.6    Traver, S.7    Lengauer, T.8    Zeuzem, S.9
  • 54
    • 34548183744 scopus 로고    scopus 로고
    • Studying hepatitis C-making the best out of a bad virus
    • (Epub ahead of print)
    • Tellinghuisen T.L., Evans M.J., von Hahn T., You S., and Rice C.M. Studying hepatitis C-making the best out of a bad virus. J. Virol. 23 May (2007) (Epub ahead of print)
    • (2007) J. Virol. , vol.23 , Issue.May
    • Tellinghuisen, T.L.1    Evans, M.J.2    von Hahn, T.3    You, S.4    Rice, C.M.5
  • 55
    • 33748603755 scopus 로고    scopus 로고
    • Hepatitis C virus NS3-4A protease inhibitors: countering viral subversion in vitro and showing promise in the clinic
    • Thomson J.A., and Perni R.B. Hepatitis C virus NS3-4A protease inhibitors: countering viral subversion in vitro and showing promise in the clinic. Curr. Opin. Drug Discov. Dev. 9 5 (2006) 606-617
    • (2006) Curr. Opin. Drug Discov. Dev. , vol.9 , Issue.5 , pp. 606-617
    • Thomson, J.A.1    Perni, R.B.2
  • 56
    • 0027176287 scopus 로고
    • NS3 is a serine protease required for processing of hepatitis C virus polyprotein
    • Tomei L., Failla C., Santolini E., De Francesco R., and La Monica N. NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J. Virol. 67 7 (1993) 4017-4026
    • (1993) J. Virol. , vol.67 , Issue.7 , pp. 4017-4026
    • Tomei, L.1    Failla, C.2    Santolini, E.3    De Francesco, R.4    La Monica, N.5
  • 57
    • 0029940111 scopus 로고    scopus 로고
    • A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease
    • Tomei L., Failla C., Vitale R.L., Bianchi E., and De Francesco R. A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease. J. Gen. Virol. 77 Pt 5 (1996) 1065-1070
    • (1996) J. Gen. Virol. , vol.77 , Issue.PART 5 , pp. 1065-1070
    • Tomei, L.1    Failla, C.2    Vitale, R.L.3    Bianchi, E.4    De Francesco, R.5
  • 58
    • 33646036163 scopus 로고    scopus 로고
    • Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034
    • Tong X., Chase R., Skelton A., Chen T., Wright-Minogue J., and Malcolm B.A. Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034. Antiviral Res. 70 2 (2006) 28-38
    • (2006) Antiviral Res. , vol.70 , Issue.2 , pp. 28-38
    • Tong, X.1    Chase, R.2    Skelton, A.3    Chen, T.4    Wright-Minogue, J.5    Malcolm, B.A.6
  • 59
    • 13144290646 scopus 로고    scopus 로고
    • Genetic heterogeneity of the NS3 protease gene in hepatitis C virus genotype 1 from untreated infected patients
    • Vallet S., Gouriou S., Nousbaum J.B., Legrand-Quillien M.C., Goudeau A., and Picard B. Genetic heterogeneity of the NS3 protease gene in hepatitis C virus genotype 1 from untreated infected patients. J. Med. Virol. 75 4 (2005) 528-537
    • (2005) J. Med. Virol. , vol.75 , Issue.4 , pp. 528-537
    • Vallet, S.1    Gouriou, S.2    Nousbaum, J.B.3    Legrand-Quillien, M.C.4    Goudeau, A.5    Picard, B.6
  • 61
    • 33645785349 scopus 로고    scopus 로고
    • Hepatitis C virus protease gene diversity in patients coinfected with human immunodeficiency virus
    • Winters M.A., Welles S.L., and Holodniy M. Hepatitis C virus protease gene diversity in patients coinfected with human immunodeficiency virus. J. Virol. 80 8 (2006) 4196-4199
    • (2006) J. Virol. , vol.80 , Issue.8 , pp. 4196-4199
    • Winters, M.A.1    Welles, S.L.2    Holodniy, M.3
  • 62
    • 33846521154 scopus 로고    scopus 로고
    • Viral determinants of resistance to treatment in patients with hepatitis C
    • Wohnsland A., Hofmann W.P., and Sarrazin C. Viral determinants of resistance to treatment in patients with hepatitis C. Clin. Microbiol. Rev. 20 1 (2007) 23-38
    • (2007) Clin. Microbiol. Rev. , vol.20 , Issue.1 , pp. 23-38
    • Wohnsland, A.1    Hofmann, W.P.2    Sarrazin, C.3
  • 63
    • 0034012630 scopus 로고    scopus 로고
    • Cross-genotypic interaction between hepatitis C virus NS3 protease domains and NS4A cofactors
    • Wright-Minogue J., Yao N., Zhang R., Butkiewicz N.J., Baroudy B.M., Lau J.Y., and Hong Z. Cross-genotypic interaction between hepatitis C virus NS3 protease domains and NS4A cofactors. J. Hepatol. 32 3 (2000) 497-504
    • (2000) J. Hepatol. , vol.32 , Issue.3 , pp. 497-504
    • Wright-Minogue, J.1    Yao, N.2    Zhang, R.3    Butkiewicz, N.J.4    Baroudy, B.M.5    Lau, J.Y.6    Hong, Z.7
  • 66


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