Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine

Nature

Volumn 418, Issue 6899, 2002, Pages 774-778

  Lindskog, Maria ^a   Svenningsson, Per ^b   Pozzi, Laura ^a,c,d   Kim, Yong ^b   Flenberg, Allen A ^b   Bibb, James A ^b,c,d   Fredholm, Bertil B ^a   Nairn, Angus C ^b   Greengard, Paul ^b   Fisone, Gilberto ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ROCKEFELLER UNIVERSITY   (United States)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVERAGES; CATALYSIS; ENZYME INHIBITION; PHYSIOLOGY; PROTEINS;

PHOSPHORYLATION;

FOOD PRODUCTS;

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE; ADENOSINE A2A RECEPTOR; CAFFEINE; CYCLIC AMP; CYCLIN DEPENDENT KINASE 5; DOPAMINE; PHOSPHOPROTEIN; PHOSPHOPROTEIN DARPP 32;

COFFEE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DEPHOSPHORYLATION; GENE DELETION; KNOCKOUT MOUSE; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

ADENOSINE; ANIMALS; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEOSTRIATUM; NERVE TISSUE PROTEINS; NEURONS; PHENETHYLAMINES; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTHREONINE; PYRIMIDINES; RECEPTORS, PURINERGIC P1; TRIAZOLES;

ANIMALIA;

EID: 0037102209     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00817     Document Type: Article

References (25)

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