Hepatocyte transplantation and drug-induced perturbations in liver cell compartments

Hepatology

Volumn 47, Issue 1, 2008, Pages 279-287

  Wu, Yao Ming ^a,b   Joseph, Brigid ^a   Berishvili, Ekaterine ^a,c   Kumaran, Vinay ^a,d   Gupta, Sanjeev ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c TBILISI STATE MEDICAL UNIVERSITY   (Georgia)

^d SIR GANGA RAM HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; DIPEPTIDYL PEPTIDASE IV; HYALURONIC ACID; MONOCROTALINE; PHENYTOIN; RIFAMPICIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG INDUCED DISEASE; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ENGRAFTMENT; ENZYME INDUCTION; HEPATOCYTE TRANSPLANTATION; HISTOCHEMISTRY; LIVER GRAFT; LIVER INJURY; LIVER PARENCHYMA; LIVER SINUSOID; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN VARIANT;

ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; ANTICONVULSANTS; ANTIGENS, CD26; CELL PROLIFERATION; ENDOTHELIAL CELLS; FEMALE; HEPATOCYTES; LIVER; LIVER FUNCTION TESTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCROTALINE; PHENYTOIN; RIFAMPIN; TIME FACTORS; TRANSPLANTS;

EID: 38649108485     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21937     Document Type: Article

References (32)

1. Tafazoli S, Spehar DD, O'Brien PJ. Oxidative stress mediated idiosyncratic drug toxicity. Drug Metab Rev 2005;37:311-325.
2. Kumaran V, Joseph B, Benten D, Gupta S. Integrin and extracellular matrix interactions regulate engraftment of transplanted hepatocytes in the rat liver. Gastroenterology 2005;129:1643-1653.
3. Wu YM, Joseph B, Gupta S. Immunosuppression using the mTOR inhibition mechanism affects replacement of the rat liver with transplanted cells. HEPATOLOGY 2006;44:410-9.
4. Benten D, Follenzi A, Bhargava KK, Kumaran V, Palestro CJ, Gupta S. Organ-specific targeting of transplanted endothelial cells in intact mice. HEPATOLOGY 2005;42:140-148.
5. Sokhi RP, Rajvanshi P, Gupta S. Transplanted reporter cells help in defining onset of hepatocyte proliferation during the life of F344 rats. Am J Physiol Gastrointest Liver Physiol 2000; 279:G631-G640.
6. Gupta S, Rajvanshi P, Sokhi R, Vaidya S, Irani AN, Gorla GR. Position-specific gene expression in the liver lobule is directed by the microenvironment and not by the previous cell differentiation state. J Biol Chem 1999;274:2157-2165.
7. Malhi H, Gorla GR, Irani AN, Annamaneni P, Gupta S. Cell transplantation after oxidative hepatic preconditioning with radiation and ischemia-reperfusion leads to extensive liver repopulation. Proc Natl Acad Sci U S A 2002;99:13114-13119.
8. Guo D, Fu T, Nelson JA, Superina RA, Soriano HE. Liver repopulation after cell transplantation in mice treated with retrosine and carbon tetrachloride. Transplantation 2002;73:1818-1824.
9. Guha C, Yamanouchi K, Jiang J, Wang X, Roy Chowdhury N, Santana A, et al. Feasibility of hepatocyte transplantation-based therapies for primary hyperoxalurias. Am J Nephrol 2005;25:161-170.
10. Kasahara Y, Kiyatake K, Tatsumi K, Sugito K, Kakusaka I, Yamagata S, et al. Bioactivation of monocrotaline by P-450 3A in rat liver. J Cardiovasc Pharmacol 1997;30:124-129.
11. DeLeve LD, Ito Y, Bethea NW, McCuskey MK, Wang X, McCuskey RS. Embolization by sinusoidal lining cells obstructs the microcirculation in rat sinusoidal obstruction syndrome. Am J Physiol Gastrointest Liver Physiol 2003;284:G1045-G1052.
12. Tofovic SP, Salah EM, Mady HH, Jackson EK, Melhem MF. Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats. J Cardiovasc Pharmacol 2005;46:430-437.
13. Shimada H, Furuno H, Hirai K, Koyama J, Ariyama J, Simamura E. Paraquat detoxicative system in the mouse liver postmitochondrial fraction. Arch Biochem Biophys 2002;402:149-157.
14. Bhuller Y, Jeng W, Wells PG. Variable in vivo embryoprotective role for ataxia-telangiectasia-mutated against constitutive and phenytoin-enhanced oxidative stress in Atm knockout mice. Toxicol Sci 2006;93:146-155.
15. Chowdhury A, Santra A, Bhattacharjee K, Ghatak S, Saha DR, Dhali GK. Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice. J Hepatol 2006;45:117-126.
16. Wang YP, Yan J, Beger RD, Fu PP, Chou MW. Metabolic activation of the tumorigenic pyrrolidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo. Cancer Lett 2005;226:27-35.
17. Guieu R, Fenouillet E, Devaux C, Fajloun Z, Carrega L, Sabatier JM, et al. CD26 modulates nociception in mice via its dipeptidyl-peptidase IV activity. Behav Brain Res 2006;166:230-235.
18. Rajvanshi P, Kerr A, Bhargava KK, Burk RD, Gupta S. Efficacy and safety of repeated hepatocyte transplantation for significant liver repopulation in rodents. Gastroenterology 1996;111:1092-1102.
19. Deaciuc IV, Bagby GJ, Lang CH, Spitzer JJ. Hyaluronic acid uptake by the isolated, perfused rat liver: An index of hepatic sinusoidal endothelial cell function. HEPATOLOGY 1992;17:262-272.
20. Kim KS, Joseph B, Inada M, Gupta S. Regulation of hepatocyte engraftment and proliferation after cytotoxic drug-induced perturbation of the rat liver. Transplantation 2005;80:653-659.
21. McKenzie R, Fried MW, Sallie R, Conjeevaram H, Di Bisceglie AM, Park Y, et al. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med 1995;333:1099-105.
22. Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov 2005;4:489-499.
23. Gordon GJ, Coleman WB, Grisham JW. Temporal analysis of hepatocyte differentiation by small hepatocyte-like progenitor cells during liver regeneration in retrorsine-exposed rats. Am J Pathol 2000;157:771-786.
24. Gupta S, Rajvanshi P, Aragona E, Yerneni PR, Lee C-D, Burk RD. Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion. Am J Physiol 1999;276:G629-G638.
25. Sokol RJ, Straka MS, Dahl R, Devereaux MW, Yerushalmi B, Gumpricht E, et al. Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatr Res 2001;49:519-531.
26. De Vree JM, Ottenhoff R, Bosma PJ, Smith AJ, Aten J, Oude Elferink RP. Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis. Gastroenterology 2000;119:1720-1730.
27. Raza M, al-Shabanah OA, al-Bekairi AM, Qureshi S. Pathomorphological changes in mouse liver and kidney during prolonged valproate administration. Int J Tissue React 2000;12:15-22
28. Oren R, Dabeva MD, Karnezis AN, Petkov PM, Rosencrantz R, Sandhu JP, et al. Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes. HEPATOLOGY 1999;30:903-913.
29. Malik R, Mellor N, Selden C, Hodgson H. Triiodothyronine enhances the regenerative capacity of the liver following partial hepatectomy. HEPATOLOGY 2003;37:79-86.
30. Joseph B, Malhi H, Bhargava KK, Palestro CJ, McCuskey RS, et al. Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver. Gastroenterology 2002;123:1677-1685.
31. Benten D, Kumaran V, Joseph B, Gupta S. Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment. HEPATOLOGY 2005;42:1072-1081.
32. Oren R, Dabeva MD, Petkov PM, Hurston E, Laconi E, Shafritz DA. Restoration of serum albumin levels in nagase analbuminemic rats by hepatocyte transplantation. HEPATOLOGY 1999;29:75-81.