-
1
-
-
50449119090
-
Primary pulmonary hypertension: I. Clinical and hemodynamic study
-
Dresdale DT, Shultz M, Michtom RH. Primary pulmonary hypertension: I. Clinical and hemodynamic study. Am J Med. 1951;11:686-705.
-
(1951)
Am J Med
, vol.11
, pp. 686-705
-
-
Dresdale, D.T.1
Shultz, M.2
Michtom, R.H.3
-
2
-
-
0000145994
-
Pulmonary hypertension with special reference to the vasoconstrictive factor
-
Wood P. Pulmonary hypertension with special reference to the vasoconstrictive factor. Br Heart J. 1959;21:557-570.
-
(1959)
Br Heart J
, vol.21
, pp. 557-570
-
-
Wood, P.1
-
3
-
-
0035676884
-
Pulmonary vascular remodeling: A garget for therapeutic intervention in pulmonary hypertension
-
Jeffery TK, Wanstall JC. Pulmonary vascular remodeling: a garget for therapeutic intervention in pulmonary hypertension. Pharmacol Ther. 2001;92:1-20.
-
(2001)
Pharmacol Ther
, vol.92
, pp. 1-20
-
-
Jeffery, T.K.1
Wanstall, J.C.2
-
4
-
-
0002498166
-
Vascular remodeling
-
Frishman AP, ed. Philadelphia: University of Pennsylvania Press
-
Reid L. Vascular remodeling. In: Frishman AP, ed. The Pulmonary Circulation: Normal and Abnormal. Philadelphia: University of Pennsylvania Press; 1990:255-282.
-
(1990)
The Pulmonary Circulation: Normal and Abnormal
, pp. 255-282
-
-
Reid, L.1
-
5
-
-
0002511367
-
Functional basis for the structure of the pulmonary arterial tree
-
JE Bishop, Reeves JT, Laurent GJ, eds. London: Portland Press
-
Reeves JT, Bishop JE, Laurent GI. Functional basis for the structure of the pulmonary arterial tree. In: JE Bishop, Reeves JT, Laurent GJ, eds. Pulmonary Vascular Remodeling. London: Portland Press; 1995:1-19.
-
(1995)
Pulmonary Vascular Remodeling
, pp. 1-19
-
-
Reeves, J.T.1
Bishop, J.E.2
Laurent, G.I.3
-
6
-
-
0036774342
-
Angiogenesis and pulmonary hypertension: A unique process in a unique disease
-
Tuder RM, Voelkel NF. Angiogenesis and pulmonary hypertension: a unique process in a unique disease. Antioxid Redox Signal. 2002;4:833-843.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 833-843
-
-
Tuder, R.M.1
Voelkel, N.F.2
-
7
-
-
0009769490
-
17β-estradiol inhibits proliferation and migration of human vascular smooth muscle cells: Similar effects in cells from postmenopausal females and in males
-
Dai-Do D, Espinosa E, Liu G, et al. 17β-Estradiol inhibits proliferation and migration of human vascular smooth muscle cells: similar effects in cells from postmenopausal females and in males. Cardiovasc Res. 1996;32:980-985.
-
(1996)
Cardiovasc Res
, vol.32
, pp. 980-985
-
-
Dai-Do, D.1
Espinosa, E.2
Liu, G.3
-
8
-
-
0021045664
-
The effects of estradiol on the proliferation of rabbit aortic media tissue culture cells induced by hyperlipemic serum
-
Fisher-Dzoga K, Wissler RW, Vesselinovich D. The effects of estradiol on the proliferation of rabbit aortic media tissue culture cells induced by hyperlipemic serum. Exp Mol Pathol. 1983;39:355-363.
-
(1983)
Exp Mol Pathol
, vol.39
, pp. 355-363
-
-
Fisher-Dzoga, K.1
Wissler, R.W.2
Vesselinovich, D.3
-
9
-
-
0027160084
-
Oestradiol inhibits smooth muscle cell proliferation of pig coronary artery
-
Vargas R, Wroblewski B, Rego A, et al. Oestradiol inhibits smooth muscle cell proliferation of pig coronary artery. Br J Pharmacol. 1993;109:612-617.
-
(1993)
Br J Pharmacol
, vol.109
, pp. 612-617
-
-
Vargas, R.1
Wroblewski, B.2
Rego, A.3
-
12
-
-
0030732109
-
Physiologic concentrations of estradiol attenuates endothelin 1-induced coronary vasoconstriction in vivo
-
Sudhir K, Ko E, Zellner C, et al. Physiologic concentrations of estradiol attenuates endothelin 1-induced coronary vasoconstriction in vivo. Circulation. 1997;96:3626-3632.
-
(1997)
Circulation
, vol.96
, pp. 3626-3632
-
-
Sudhir, K.1
Ko, E.2
Zellner, C.3
-
13
-
-
0027165908
-
Protection by oestradiol against the development of cardiovascular changes associated with monocrotaline pulmonary hypertension in rats
-
Farhat MY, Chen MF, Bhatti T, et al. Protection by oestradiol against the development of cardiovascular changes associated with monocrotaline pulmonary hypertension in rats. Br J Pharm. 1993;110:719-723.
-
(1993)
Br J Pharm
, vol.110
, pp. 719-723
-
-
Farhat, M.Y.1
Chen, M.F.2
Bhatti, T.3
-
14
-
-
0034094778
-
Estradiol improves pulmonary hemodynamics and vascular remodeling in perinatal pulmonary hypertension
-
Parker TA, Ivy DD, Galan HL, et al. Estradiol improves pulmonary hemodynamics and vascular remodeling in perinatal pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2000;278:L374-L381.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.278
-
-
Parker, T.A.1
Ivy, D.D.2
Galan, H.L.3
-
16
-
-
0035015033
-
Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression
-
Resta TC, Knaggy NL, Walker BR. Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression. Am J Physiol Lung Cell Mol Physiol. 2001;280:L88-L97.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.280
-
-
Resta, T.C.1
Knaggy, N.L.2
Walker, B.R.3
-
17
-
-
2342667629
-
Primary pulmonary hypertension: An overview of epidemiology and pathogenesis
-
Ghamra ZW, Dweik RA. Primary pulmonary hypertension: an overview of epidemiology and pathogenesis. Cleve Clin J Med. 2003;70: S2-S8.
-
(2003)
Cleve Clin J Med
, vol.70
-
-
Ghamra, Z.W.1
Dweik, R.A.2
-
19
-
-
0031847271
-
An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats
-
Liu D, Bachmann KA. An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats. J Pharmacol Exp Ther. 1998;286:561-568.
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 561-568
-
-
Liu, D.1
Bachmann, K.A.2
-
21
-
-
0020603477
-
Metabolic clearance rates of catechol estrogens in rats
-
Ball P, Emons G, Kayser H, et al. Metabolic clearance rates of catechol estrogens in rats. Endocrinology. 1983;113:1781-1783.
-
(1983)
Endocrinology
, vol.113
, pp. 1781-1783
-
-
Ball, P.1
Emons, G.2
Kayser, H.3
-
22
-
-
0037320432
-
2-Methoxyestardiol, a promising anticancer drug
-
Lakham NJ, Sarkar MA, Venitz J, et al. 2-Methoxyestardiol, a promising anticancer drug. Pharmacotherapy. 2003;23:165-172.
-
(2003)
Pharmacotherapy
, vol.23
, pp. 165-172
-
-
Lakham, N.J.1
Sarkar, M.A.2
Venitz, J.3
-
23
-
-
0036645421
-
2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors alpha and beta
-
LaVallee TM, Zhan XH, Herbstritt CJ, et al. 2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors alpha and beta. Cancer Res. 2002;62:3691-3697.
-
(2002)
Cancer Res
, vol.62
, pp. 3691-3697
-
-
Lavallee, T.M.1
Zhan, X.H.2
Herbstritt, C.J.3
-
24
-
-
0024373582
-
The cytotoxic effects of estradiol-17 beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and Hela Cells
-
Seegers JC, Aveling MO, Van Aswegen CH, et al. The cytotoxic effects of estradiol-17 beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and Hela Cells. J Steroid Biochem. 1989;32:797-809.
-
(1989)
J Steroid Biochem
, vol.32
, pp. 797-809
-
-
Seegers, J.C.1
Aveling, M.O.2
Van Aswegen, C.H.3
-
25
-
-
0028901425
-
Anti-proliferative effect of 2-methoxyestradiol on cultured smooth muscle cells from rabbit aorta
-
Nishigaki I, Sasaguri Y, Yagi K. Anti-proliferative effect of 2-methoxyestradiol on cultured smooth muscle cells from rabbit aorta. Atherosclerosis. 1995;113:167-170.
-
(1995)
Atherosclerosis
, vol.113
, pp. 167-170
-
-
Nishigaki, I.1
Sasaguri, Y.2
Yagi, K.3
-
26
-
-
0031606441
-
17β-estradiol, its metabolites and progesterone inhibit cardiac fibroblast growth
-
Dubey RK, Gillespie DG, Jackson EK, et al. 17β-estradiol, its metabolites and progesterone inhibit cardiac fibroblast growth. Hypertension. 1998;31:522-528.
-
(1998)
Hypertension
, vol.31
, pp. 522-528
-
-
Dubey, R.K.1
Gillespie, D.G.2
Jackson, E.K.3
-
27
-
-
0034638620
-
Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms
-
Dubey RK, Gillespie DG, Zacharia LC, et al. Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms. Biochem Biophys Res Commun. 2000;278:27-33.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 27-33
-
-
Dubey, R.K.1
Gillespie, D.G.2
Zacharia, L.C.3
-
28
-
-
0035095739
-
Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism
-
Dubey RK, Jackson EK, Keller PJ, et al. Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism. Hypertension. 2001;37:640-644.
-
(2001)
Hypertension
, vol.37
, pp. 640-644
-
-
Dubey, R.K.1
Jackson, E.K.2
Keller, P.J.3
-
29
-
-
0033588490
-
Effects of estradiol metabolites on prostacyclin synthesis in human endothelial cell cultures
-
Seeger H, Mueck AO, Lippert TH. Effects of estradiol metabolites on prostacyclin synthesis in human endothelial cell cultures. Life Sci. 1999;65:167-170.
-
(1999)
Life Sci
, vol.65
, pp. 167-170
-
-
Seeger, H.1
Mueck, A.O.2
Lippert, T.H.3
-
30
-
-
0032499891
-
2-Methoxyestradiol, an endogenous metabolite of estrogen, enhances apoptosis and beta-galactosidase expression in vascular endothelial cells
-
Tsukamoto A, Kaneko Y, Yoshida T, et al. 2-Methoxyestradiol, an endogenous metabolite of estrogen, enhances apoptosis and beta-galactosidase expression in vascular endothelial cells. Biochem Biophys Res Commun. 1998;248:9-12.
-
(1998)
Biochem Biophys Res Commun
, vol.248
, pp. 9-12
-
-
Tsukamoto, A.1
Kaneko, Y.2
Yoshida, T.3
-
31
-
-
0036245561
-
Janus face of vascular endothelial growth factor: The obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension
-
Voelkel NF, Cool C, Taraceviene-Stewart L, et al. Janus face of vascular endothelial growth factor: the obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Crit Care Med. 2002;30:S251-S256.
-
(2002)
Crit Care Med
, vol.30
-
-
Voelkel, N.F.1
Cool, C.2
Taraceviene-Stewart, L.3
-
32
-
-
0035192862
-
2-Hydroxyestradiol attenuates the development of obesity, metabolic syndrome, and vascular and renal dysfunction in obese ZSF1 rats
-
Tofovic SP, Dubey RK, Jackson EK.2-Hydroxyestradiol attenuates the development of obesity, metabolic syndrome, and vascular and renal dysfunction in obese ZSF1 rats. J Pharmacol Exp Ther. 2001;299:973-977.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 973-977
-
-
Tofovic, S.P.1
Dubey, R.K.2
Jackson, E.K.3
-
33
-
-
0036839384
-
2-Hydroxyestradiol attenuates renal disease in chronic puromycin aminonucleoside nephropathy
-
Tofovic SP, Dubey R, Salah EM, et al. 2-Hydroxyestradiol attenuates renal disease in chronic puromycin aminonucleoside nephropathy. J Am Soc Nephrol. 2002;13:2737-2747.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2737-2747
-
-
Tofovic, S.P.1
Dubey, R.2
Salah, E.M.3
-
34
-
-
21444459241
-
Estradiol metabolites attenuate renal injury induced by chronic nitric oxide synthase inhibition
-
Tofovic SP, Salah EM, Dubey RK, et al. Estradiol metabolites attenuate renal injury induced by chronic nitric oxide synthase inhibition. J Cardiovasc Pharmacol. 2005;46:25-35.
-
(2005)
J Cardiovasc Pharmacol
, vol.46
, pp. 25-35
-
-
Tofovic, S.P.1
Salah, E.M.2
Dubey, R.K.3
-
35
-
-
2442703499
-
Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic angiotensin II administration
-
Tofovic SP, Maddy H, Jackson EK. Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic angiotensin II administration [abstract]. Hypertension. 2003;42:414.
-
(2003)
Hypertension
, vol.42
, pp. 414
-
-
Tofovic, S.P.1
Maddy, H.2
Jackson, E.K.3
-
36
-
-
21444451455
-
2-Methoxyestradiol attenuates hypertension and cardiac and vascular remodeling in constricted aorta rat model
-
Tofovic SP, Jackson EK, Mady H.2-Methoxyestradiol attenuates hypertension and cardiac and vascular remodeling in constricted aorta rat model [abstract]. J Am Soc Nephrol. 2003;14:620A.
-
(2003)
J Am Soc Nephrol
, vol.14
-
-
Tofovic, S.P.1
Jackson, E.K.2
Mady, H.3
-
37
-
-
0034126770
-
Complete reversal of fatal pulmonary hypertension in rat by a serine elastase inhibitor
-
Cowan KN, Heilbut A, Humpl T, et al. Complete reversal of fatal pulmonary hypertension in rat by a serine elastase inhibitor. Nat Med. 2000;6:698-701.
-
(2000)
Nat Med
, vol.6
, pp. 698-701
-
-
Cowan, K.N.1
Heilbut, A.2
Humpl, T.3
-
38
-
-
0024245337
-
Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension
-
Rosenberg H, Rabinovitch M. Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension. Am J Physiol. 1988;255: H1484-H1491.
-
(1988)
Am J Physiol
, vol.255
-
-
Rabinovitch, H.1
Rabinovitch, M.2
-
39
-
-
0027062783
-
Mechanisms of pathology of monocrotaline toxicity
-
Wilson DW, Segal HJ, Pan LC, et al. Mechanisms of pathology of monocrotaline toxicity. Crit Rev Toxicol. 1992;22:307-325.
-
(1992)
Crit Rev Toxicol
, vol.22
, pp. 307-325
-
-
Wilson, D.W.1
Segal, H.J.2
Pan, L.C.3
-
40
-
-
0025663083
-
Formation, metabolism, and physiological importance of catecholestrogens
-
Ball P, Knuppen R. Formation, metabolism, and physiological importance of catecholestrogens. Am J Obstet Gynecol. 1990;163:2163-2170.
-
(1990)
Am J Obstet Gynecol
, vol.163
, pp. 2163-2170
-
-
Ball, P.1
Knuppen, R.2
-
42
-
-
26044475423
-
2-Methoxyestradiol mediates protective effects of estradiol in monocrotaline-induced pulmonary hypertension
-
Tofovic SP, Jackson EK, Zhang X.2-Methoxyestradiol mediates protective effects of estradiol in monocrotaline-induced pulmonary hypertension [abstract]. Circulation. 2004;110(suppl III):III-18.
-
(2004)
Circulation
, vol.110
, Issue.SUPPL. III
-
-
Tofovic, S.P.1
Jackson, E.K.2
Zhang, X.3
-
43
-
-
0032126807
-
Pulmonary hypertension and inflammation
-
Tuder RM, Voelkel NF. Pulmonary hypertension and inflammation. J Lab Clin Med. 1998;132:16-24.
-
(1998)
J Lab Clin Med
, vol.132
, pp. 16-24
-
-
Tuder, R.M.1
Voelkel, N.F.2
-
44
-
-
0034769436
-
Proliferating cell nuclear antigen (PCNA): Ringmaster of the genome
-
Paunesku T, Mittal S, Protic M, et al. Proliferating cell nuclear antigen (PCNA): ringmaster of the genome. Int J Radiat Biol. 2001;77:1007-1021.
-
(2001)
Int J Radiat Biol
, vol.77
, pp. 1007-1021
-
-
Paunesku, T.1
Mittal, S.2
Protic, M.3
-
45
-
-
0030949341
-
2-Methopxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: Possible role for stress-activated protein kinase signaling pathway and Fas expression
-
Yue T-I, Wang X, Louden CS, et al. 2-Methopxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: Possible role for stress-activated protein kinase signaling pathway and Fas expression. Mol Pharmacol. 1997;51:951-962.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 951-962
-
-
Yue, T.-I.1
Wang, X.2
Louden, C.S.3
-
46
-
-
0037382060
-
Novel 2-methoxyestradiol analogues with antitumor activity
-
Tinley TL, Leal RM, Randall-Hlubek DA, et al. Novel 2-methoxyestradiol analogues with antitumor activity. Cancer Res. 2003;63:1538-1549.
-
(2003)
Cancer Res
, vol.63
, pp. 1538-1549
-
-
Tinley, T.L.1
Leal, R.M.2
Randall-Hlubek, D.A.3
-
47
-
-
0034993154
-
The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors
-
Schumacher G, Neuhaus P. The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors. J Cancer Res Clin Oncol. 2001;127:405-410.
-
(2001)
J Cancer Res Clin Oncol
, vol.127
, pp. 405-410
-
-
Schumacher, G.1
Neuhaus, P.2
-
48
-
-
0034683065
-
The effects of A-ring and D-ring metabolites of estradiol on the proliferation of vascular endothelial cells
-
Lippert C, Seeger H, Mueck AO, et al. The effects of A-ring and D-ring metabolites of estradiol on the proliferation of vascular endothelial cells. Life Sci. 2000;67:1653-1658.
-
(2000)
Life Sci
, vol.67
, pp. 1653-1658
-
-
Lippert, C.1
Seeger, H.2
Mueck, A.O.3
-
49
-
-
0035130107
-
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
-
Taraseviciene-Stewart L, Kasahara Y, Alger L, et al. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J. 2001;15:427-438.
-
(2001)
FASEB J
, vol.15
, pp. 427-438
-
-
Taraseviciene-Stewart, L.1
Kasahara, Y.2
Alger, L.3
|