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Volumn , Issue , 2006, Pages 415-419

Structure-Function Strategies to Improve the Pharmacological Value of Animal Toxins

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EID: 38549150808     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012369442-3/50062-3     Document Type: Chapter
Times cited : (4)

References (24)
  • 1
    • 0033544906 scopus 로고    scopus 로고
    • Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity
    • Alessandri-Haber N, Lecoq A, Gasparini S, Grangier-Macmath G, Jacquet G, Harvey AL, et al. Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity. J Biol Chem 1999, 274:35653-35661.
    • (1999) J Biol Chem , vol.274 , pp. 35653-35661
    • Alessandri-Haber, N.1    Lecoq, A.2    Gasparini, S.3    Grangier-Macmath, G.4    Jacquet, G.5    Harvey, A.L.6
  • 2
    • 20144366005 scopus 로고    scopus 로고
    • Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases
    • Beeton C, Pennington MW, Wulff H, Singh S, Nugent D, Crossley G, et al. Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases. Mol Pharmacol 2005, 67:1369-1381.
    • (2005) Mol Pharmacol , vol.67 , pp. 1369-1381
    • Beeton, C.1    Pennington, M.W.2    Wulff, H.3    Singh, S.4    Nugent, D.5    Crossley, G.6
  • 3
    • 0030783712 scopus 로고    scopus 로고
    • Solution structure of maurotoxin, a scorpion toxin from scorpio maurus, with high affinity for voltagegated potassium channels
    • Blanc E, Sabatier JM, Kharrat R, Meunier S, El Ayeb M, Van Rietschoten J, et al. Solution structure of maurotoxin, a scorpion toxin from scorpio maurus, with high affinity for voltagegated potassium channels. Proteins 1997, 29:321-333.
    • (1997) Proteins , vol.29 , pp. 321-333
    • Blanc, E.1    Sabatier, J.M.2    Kharrat, R.3    Meunier, S.4    El Ayeb, M.5    Van Rietschoten, J.6
  • 4
    • 6544276937 scopus 로고    scopus 로고
    • On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures
    • Dauplais M, Lecoq A, Song J, Cotton J, Jamin N, Gilquin B, et al. On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J Biol Chem 1997, 272:4302-4309.
    • (1997) J Biol Chem , vol.272 , pp. 4302-4309
    • Dauplais, M.1    Lecoq, A.2    Song, J.3    Cotton, J.4    Jamin, N.5    Gilquin, B.6
  • 5
    • 0347915528 scopus 로고    scopus 로고
    • Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-Implications for immunological studies
    • de Haan EC, Wauben MH, Wagenaar-Hilbers JP, Grosfeld-Stulemeyer MC, Rijkers DT, Moret EE, et al. Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-Implications for immunological studies. Mol Immunol 2004, 40:943-948.
    • (2004) Mol Immunol , vol.40 , pp. 943-948
    • de Haan, E.C.1    Wauben, M.H.2    Wagenaar-Hilbers, J.P.3    Grosfeld-Stulemeyer, M.C.4    Rijkers, D.T.5    Moret, E.E.6
  • 7
    • 20144388051 scopus 로고    scopus 로고
    • Transduction of the scorption toxin maurocalcine into cells-Evidence that the toxin crosses the plasma membrane
    • Estève E, Mabrouk K, Dupuis A, Smida-Rezgui S, Altafaj X, Grunwald D, et al. Transduction of the scorption toxin maurocalcine into cells-Evidence that the toxin crosses the plasma membrane. J Biol Chem 2005, 280:12833-12839.
    • (2005) J Biol Chem , vol.280 , pp. 12833-12839
    • Estève, E.1    Mabrouk, K.2    Dupuis, A.3    Smida-Rezgui, S.4    Altafaj, X.5    Grunwald, D.6
  • 8
    • 0034607464 scopus 로고    scopus 로고
    • 1H NMR structure, and activity of a three-disulfide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins
    • 1H NMR structure, and activity of a three-disulfide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins. J Biol Chem 2000, 275:13605-13612.
    • (2000) J Biol Chem , vol.275 , pp. 13605-13612
    • Fajloun, Z.1    Ferrat, G.2    Carlier, E.3    Fathallah, M.4    Lecomte, C.5    Sandoz, G.6
  • 9
    • 0034672022 scopus 로고    scopus 로고
    • Maurotoxin Versus Pi1/HsTx1 toxins: Toward new insights in the understanding of their distinct disulfide bridge patterns
    • Fajloun Z, Mosbah A, Carlier E, Mansuelle P, Sandoz G, Fathallah M, et al. Maurotoxin Versus Pi1/HsTx1 toxins: Toward new insights in the understanding of their distinct disulfide bridge patterns. J Biol Chem 2000, 275:39394-39402.
    • (2000) J Biol Chem , vol.275 , pp. 39394-39402
    • Fajloun, Z.1    Mosbah, A.2    Carlier, E.3    Mansuelle, P.4    Sandoz, G.5    Fathallah, M.6
  • 10
    • 17144413324 scopus 로고    scopus 로고
    • Immunology of scorption toxins and perspectives for generation of antivenom vaccines
    • Gazarian KG, Gazarian T, Hernández R, Possani LD Immunology of scorption toxins and perspectives for generation of antivenom vaccines. Vaccine 2005, 23:3357-3368.
    • (2005) Vaccine , vol.23 , pp. 3357-3368
    • Gazarian, K.G.1    Gazarian, T.2    Hernández, R.3    Possani, L.D.4
  • 11
    • 0037020077 scopus 로고    scopus 로고
    • Structure of the BgK-Kv1.1 complex based on distance restrains identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers
    • Gilquin B, Racape J, Wrisch A, Visan V, Lecoq A, Grissmer S, et al. Structure of the BgK-Kv1.1 complex based on distance restrains identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers. J Biol Chem 2002, 277:37406-37413.
    • (2002) J Biol Chem , vol.277 , pp. 37406-37413
    • Gilquin, B.1    Racape, J.2    Wrisch, A.3    Visan, V.4    Lecoq, A.5    Grissmer, S.6
  • 12
    • 21044438453 scopus 로고    scopus 로고
    • Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth
    • Huang CC, Stricher F, Martin L, Decker JM, Majeed S, Barthe P, et al. Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Structure 2005, 13:755-768.
    • (2005) Structure , vol.13 , pp. 755-768
    • Huang, C.C.1    Stricher, F.2    Martin, L.3    Decker, J.M.4    Majeed, S.5    Barthe, P.6
  • 14
    • 14844304314 scopus 로고    scopus 로고
    • Effective tumor targeting: strategies for the delivery of armed antibodies
    • MacDonald GC, Glover N Effective tumor targeting: strategies for the delivery of armed antibodies. Curr Opin Drug Discov Devel 2005, 8:177-183.
    • (2005) Curr Opin Drug Discov Devel , vol.8 , pp. 177-183
    • MacDonald, G.C.1    Glover, N.2
  • 15
    • 23044500282 scopus 로고    scopus 로고
    • Increasing the molecular contacts between maurotoxin and Kvl.2 channel augments ligand affinity
    • M'Barek S, Chagot B, Andreotti N, Visan V, Mansuelle P, Grissmer S, et al. Increasing the molecular contacts between maurotoxin and Kvl.2 channel augments ligand affinity. Proteins 2005, 60:401-411.
    • (2005) Proteins , vol.60 , pp. 401-411
    • M'Barek, S.1    Chagot, B.2    Andreotti, N.3    Visan, V.4    Mansuelle, P.5    Grissmer, S.6
  • 18
    • 14044270108 scopus 로고    scopus 로고
    • Contribution of the functional dyad of animal toxins acting on voltage-gated Kv1-type channels
    • Mouhat S, De Waard M, Sabatier JM Contribution of the functional dyad of animal toxins acting on voltage-gated Kv1-type channels. J Pep Sci 2005, 11:65-68.
    • (2005) J Pep Sci , vol.11 , pp. 65-68
    • Mouhat, S.1    De Waard, M.2    Sabatier, J.M.3
  • 19
    • 11244306404 scopus 로고    scopus 로고
    • Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
    • Regaya I, Beeton C, Ferrat G, Andreotti N, Darbon H, De Waard M, et al. Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins. J Biol Chem 2004, 279:55690-55696.
    • (2004) J Biol Chem , vol.279 , pp. 55690-55696
    • Regaya, I.1    Beeton, C.2    Ferrat, G.3    Andreotti, N.4    Darbon, H.5    De Waard, M.6
  • 22
    • 0003621201 scopus 로고    scopus 로고
    • Chemical synthesis and characterization of small proteins: example of scorption toxins
    • Birkhaüser Verlag, Basel, Switzerland, H. Rochat, M.F. Martin-Eauclaire (Eds.)
    • Sabatier JM Chemical synthesis and characterization of small proteins: example of scorption toxins. Animal toxins 2000, 196-216. Birkhaüser Verlag, Basel, Switzerland. H. Rochat, M.F. Martin-Eauclaire (Eds.).
    • (2000) Animal toxins , pp. 196-216
    • Sabatier, J.M.1
  • 24
    • 0031081412 scopus 로고    scopus 로고
    • In vivo protection against Androctonus australis hector scorption toxin and venom by immunization with a synthetic anlog of toxin II
    • Zenouaki I, Kharrat R, Sabatier JM, Devaux C, Karoui H, Van Reitschoten J, et al. In vivo protection against Androctonus australis hector scorption toxin and venom by immunization with a synthetic anlog of toxin II. Vaccine 1997, 15.
    • (1997) Vaccine , vol.15
    • Zenouaki, I.1    Kharrat, R.2    Sabatier, J.M.3    Devaux, C.4    Karoui, H.5    Van Reitschoten, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.