Tobacco smoking inhibits expression of proinflammatory cytokines and activation of IL-1R-associated kinase, p38, and NF-κB in alveolar macrophages stimulated with TLR2 and TLR4 agonists

Journal of Immunology

Volumn 179, Issue 9, 2007, Pages 6097-6106

  Chen, Haiyan ^a   Cowan, Mark J ^a   Hasday, Jeffrey D ^a   Vogel, Stefanie N ^a   Medvedev, Andrei E ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN MD 2; RANTES; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MONOCYTE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOKING; ADULT; CELL CULTURE; DRUG POTENTIATION; GENE EXPRESSION REGULATION; METABOLISM; MIDDLE AGED;

ADULT; ANTIGENS, CD14; CELLS, CULTURED; CYTOKINES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LYMPHOCYTE ANTIGEN 96; MACROPHAGES; MIDDLE AGED; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SMOKING; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 38449089993     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.9.6097     Document Type: Article

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