Genomics of Economically Significant Aspergillus and Fusarium Species

Applied Mycology and Biotechnology

Volumn 4, Issue C, 2004, Pages 249-283

  Yu, Jiujiang ^a   Proctor, Robert H ^a   Brown, Daren W ^e   Abe, Keietsu ^b   Gomi, Katsuya ^b   Machida, Masayuki ^c   Hasegawa, Fumihiko ^b   Nierman, William C ^d   Bhatnagar, Deepak ^a   Cleveland, Thomas E ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b TOHOKU UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d J CRAIG VENTER INSTITUTE   (United States)

^e Institute for Genomic Research ^*

Author keywords

[No Author keywords available]

Indexed keywords

EID: 3843127972     PISSN: 18745334     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1874-5334(04)80013-3     Document Type: Chapter

References (155)

1. Adams T.H., and Yu J.H. Coordinate control of secondary metabolite production and asexual sporulation in Aspergillus nidulans. Curr Opin Microbiol 1 (1998) 674-677
2. Alexander N.J., McCormick S.P., and Hohn T.M. TRI12, a trichothecene efflux pump from Fusarium sporotrichioides: gene isolation and expression in yeast. Mol Gen Genet 261 (1999) 977-984
3. Review. Beffa T., Staib F., Lott F.J., Lyon P.F., Gumowski P., Marfenina O.E., Dunoyer-Geindre S., Georgen F., Roch-Susuki R., Gallaz L., and Latge J.P. Mycological control and surveillance of biological waste and compost. Med Mycol 36 Suppl 1 (1988) 137-145
4. Bennett J.W. Mycotoxigenic fungi in southern crops: interaction of fungal genetics and environmental factors that influence selection of toxin-producing populations. Final Report Cooperative Agreement 58-7B30-3-556 (1987)
5. Bennett J.W. Open letter to fungal researchers. Fungal Genet Biol 21 (1997) 22
6. Bennett J.W. White paper: genomics for filamentous fungi. Fungal Genet Biol 21 (1997) 3-7
7. Bennett J.W., and Arnold J. Genomics for fungi. The Mycota VIII, Biology of the Fungal Cell (2001), Springer-Verlag, Heidelberg, Berlin 267-297
8. Bennett J.W., and Klich M.A. Aspergillus - Biology and Industrial Applications (1992), Butterworth-Heinemann, Stoneham, Massachusetts
9. Berka R.M., Ward M., Wilson L.J., Hayenga K.J., Kodama K.H., Carlomagno L.P., and Thompson S.A. Molecular cloning and deletion of the gene encoding aspergillopepsin A from Aspergillus awamori. Gene 86 (1990) 153-162
10. Betina V. Mycotoxins: Chemical, Biological and Environmental Aspects (1989), Elsevier Publisher, Amsterdam-Oxford-New York, Tokyo
11. Bhatnagar D., Yu J., and Ehrlich K.C. Toxins of filamentous fungi. In: Breitenbach M., Crameri R., and Lehrer S. (Eds). Fungal Allergy and Pathogenicity. Chem Immunol Vol 81 (2002), Karger, Basel 167-206
12. Bhatnagar D., Yu J., and Cleveland T.E. Applying the genomic wrench-New tool for an old problem. Mycopathologia 155 (2002) 159
13. Bhatnagar D., Yu J., and Cleveland T.E. Applying the genomic wrench-New tool for an old problem. Mycopathologia 155 (1902) 159
14. Blackwell B.A., Miller J.D., and Savard M.E. Production of carbon 14-labeled fumonisin in liquid culture. J AOAC Int 77 (1994) 506-511
15. Brandwagt B.F., Mesbah L.A., Takken F.L., Laurent P.L., Kneppers T.J., Hille J., and Nijkamp H.J. A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp. lycopersici toxins and fumonisin Bl. Proc Natl Acad Sci USA 97 (2000) 4961-4966
16. 1 by Fusarium moniliforme. Mycopathologia 124 (1993) 99-104
17. Brody H., and Carbon J. Electrophoretic karyotype of Aspergillus nidulans. Proc Natl Acad Sci USA 86 (1989) 6260-6263
18. Brown D.W., Yu J.-H., Kelkar H.S., Fernandes M., Nesbitt T.C., Keller N.P., Adams T.H., and Leonard T.J. Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans. Proc Natl Acad Sci USA 93 (1996) 1418-1422
19. Brown R.L., Bhatnagar D., Cleveland T.E., and Cary J.W. Recent advances in preharvest prevention of mycotoxin contamination. In: Sinha K.K., and Bhatnagar D. (Eds). Mycotoxins in Agriculture and Food Safety (1998), Marcel Dekker, New York 351-379
20. Brown D.W., McCormick S.P., Alexander N.J., Proctor R.H., and Desjardins A.E. Inactivation of a cytochrome P- 450 is a determinant of trichothecene diversity in Fusarium species. Fungal Genet Biol 36 (2002) 224-233
21. Brown DW, Proctor RH, Dyer RB, and Plattner RD (2003) Unpublished observations.
22. Busby Jr. W.F., and Wogan G.N. Aflatoxins. In: Shank R.C. (Ed). Mycotoxins and N-nitrosocompounds: Environmental Risks Vol 2 (1981), CRC Press, Boca Raton 3-45
23. 1 and AAL toxins. J Agric Food Chem 46 (1998) 4734-4743
24. Casadevall A., and Pirofski L.-A. Host-pathogen interactions: Redefining the basic concepts of virulence and pathogenicity. Infect Immun 67 (1999) 3703-3713
25. Chang J.M., Oyaizu H., and Sugiyama J. Phylogenetic relationship among eleven selected species of Aspergillus and associated teleomorphic genera estimated from 18S ribosomal RNA partial sequences. J Gen Appl Microbiol 37 (1991) 289-308
26. Chang P.K., Skory C.D., and Linz J.E. Cloning of a gene associated with aflatoxin Bl biosynthesis in Aspergillus parasiticus. Curr Genet 21 (1992) 231-233
27. Chang P.-K., Cary J.W., Bhatnagar D., Cleveland T.E., Bennett J.W., Linz J.E., Woloshuk C.P., and Payne G.A. Cloning of the Aspergillus parasiticus apa-2 gene associated with the regulation of aflatoxin biosynthesis. Appl Environ Microbiol 59 (1993) 3273-3279
28. 1 . Mol Gen Genet 248 (1995) 270-277
29. Chang P.-K., Ehrlich K.C., Yu J., Bhatnagar D., and Cleveland T.E. Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA binding protein, relieves nitrate inhibition of aflatoxin biosynthesis. Appl Environ Microbiol 61 (1995) 2372-2377
30. Chang P.-K., Yu J., Bhatnagar D., and Cleveland T.E. Repressor-AFLR interaction modulates aflatoxin biosynthesis in Aspergillus parasiticus. Mycopathologia 147 (1999) 105-112
31. Chang P.-K., Yu J., Bhatnagar D., and Cleveland T.E. The carboxy-terminal portion of the aflatoxin pathway regulatory protein AFLR of Aspergillus parasiticusactivates GALl:lacZ gene expression in Saccharomyces cerevisiae. Appl Environ Microbiol 65 (1999) 2058-2512
32. Chang P.-K., and Yu J. Characterization of a partial duplication of the aflatoxin gene cluster in Aspergillus parasiticus ATCC 56775. Appl Microbiol Biotechnol 58 (2002) 632-636
33. Chigira Y., Abe K., Gomi K., and Nakajima T. chsZ, a gene for a novel class of chitin synthase from Aspergillus oryzae. Curr Genet 41 (2002) 261-267
34. Chu F.S. Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures. Mutat Res 259 (1991) 291-306
35. Cleveland T.E., Cary J.W., Brown R.L., Bhatnagar D., Yu J., Chang P.K., Chlan C.A., and Rajasekaran K. Use of biotechnology to eliminate aflatoxin in preharvest crops. Bull Inst Compr Agr Sci Kinki Univ 5 (1997) 75-90
36. Cole R.J., and Cox E.H. Handbook of Toxic Fungal Metabolites (1987), Academic Press, New York
37. 1 . Cancer Res 47 (1987) 1913-1917
38. Dasbach E.J., Davies G.M., and Teutsch S.M. Burden of aspergillosis-related hospitalizations in the United States. Clin Infect Dis 31 (2000) 1524-1528
39. de G.M., Bundock P., Hooykaas P.J., and Beijersbergen A.G. Agrobacterium tumefaciens-mediated transformation of filamentous fungi. Nat Biotechnol 16 (1998) 839-842
40. De N.M., Rombouts F., and Notermans S. Fusarium molds and their mycotoxins. J Food Saf 16 (1996) 15-58
41. Debets F., Swart K., Hockstra R.F., and Bos C.J. Genetic maps of eight linkage groups of Aspergillus niger based on mitotic mapping. Curr Genet 23 (1993) 47-53
42. Denning D.W. Therapeutic outcome of invasive aspergillosis. Clin Infect Dis 23 (1996) 608-615
43. Denning D.W. Invasive aspergillosis. Clin Infect Dis 26 (1998) 781-805
44. Desjardins A.E., and Proctor R.H. Biochemistry and genetics ofFusarium toxins. In: Summerell B., Leslie J.F., Backhouse D., Bryden W.L., and Burgess L.W. (Eds). Fusarium: Paul E. Nelson Symposium. St Paul: APS Press (1999)
45. Desjardins A.E., Hohn T.M., and McCormick S.P. Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance. Microbiol Rev 57 (1993) 595-604
46. Desjardins A.E., Proctor R.H., Bai G., McCormick S.P., Shaner G., Buechley G., and Hohn T.M. Reduced virulence of trichothecene-nonproducing mutants of Gibberella zeae in wheat field tests. Mol Plant-Microbe Interact 9 (1996) 775-781
47. Dujon B. The yeast genome project: what did we learn?. Trends Genet 12 (1996) 263-270
48. Dunn-Coleman N., and Prade R. Toward a global filamentous fungus genome sequencing effort. Nature Biotech 16 (1998) 5
49. Eaton D.L., and Groopman J.D. The Toxicology of Aflatoxins-Human Health. Veterinary and Agricultural Significance (1994), Academic Press, New York
50. Ehrlich K.C., Montalbano B.G., Bhatnagar D., and Cleveland T.E. Alteration of different domains in AFLR affects aflatoxin pathway metabolism in Aspergillus parasiticus transformants. Fungal Genet Biol 23 (1998) 279-287
51. Ehrlich K.C., Cary J.W., and Montalbano B.G. Characterization of the promoter for the gene encoding the aflatoxin biosynthetic pathway regulatory protein AFLR. Biochim Biophys Acta 1444 (1999) 412-417
52. Ehrlich K.C., Montalbano B.G., and Cary J.W. Binding of the C6-zinc cluster protein, AFLR, to the promoters of aflatoxin pathway biosynthesis genes in Aspergillus parasiticus. Gene 230 (1999) 249-257
53. Fernandes M., Keller N.P., and Adams T.H. Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis. Mol Microbiol 28 (1998) 1355-1365
54. Flaherty J.E., and Payne G.A. Overexpression of aflR leads to upregulation of pathway gene expression and increased aflatoxin production in Aspergillus flavus. Appl Environ Microbiol 63 (1997) 3995-4000
55. Foutz K.R., Woloshuk C.P., and Payne G.A. Cloning and assignment of linkage group loci to a karyotypic map of the filamentous fungus Aspergillus flavus. Mycologia 87 (1995) 787-794
56. Frisvad J.C., and Samson R.A. New producers of aflatoxin. In: Samson R.A., and Pitt J.I. (Eds). Interaction of molecular and morphological approaches to Aspergillus and Penicillium taxonomy (1999), Harwood, Reading
57. Galvano F., Galofaro V., and Galvano G. Occurrence and stability of aflatoxin MI in milk and milk products: A worldwide review. J Food Protect 59 (1996) 1079-1090
58. Gems D., and JohnstonelL C.A. An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. Gene 98 (1991) 61-67
59. nd 2 ed. (1996), Stockton Press, New York
60. Goffeau A., Barrell B.G., Bussey H., Davis R.W., Dujon B., Feldmann H., Galibert F., Hoheisel J.D., Jacq C., Johnston M., Louis E.J., Mewes H.W., Murakami Y., Philippsen P., Tettelin H., and Oliver S.G. Life with 6000 genes. Science 274 5287 (1996) 546
61. Review. Goffeau A., Barrell B.G., Bussey H., Davis R.W., Dujon B., Feldmann H., Galibert F., Hoheisel J.D., Jacq C., Johnston M., Louis E.J., Mewes H.W., Murakami Y., Philippsen P., Tettelin H., and Oliver S.G. Life with 6000 genes. Science 274 5287 (1996) 563-567
62. Suppl. Goffeau A., Aert R., Agostini-Carbone M.L., Ahmed A., Aigle M., Alberghina L., Albermann K., Albers M., et al. The yeast genome directory. Nature 387 6632 (1997) 5
63. Goffeau A., Park J., Paulsen I.T., Jonniaux J.L., Dinh T., Mordant P., and Saier Jr. M.H. Multidrug-resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames with the major facilitator superfamily. Yeast 13 (1997) 43-54
64. Goldblatt L.A. Aflatoxin-Scientific Background, Control and Implications (1969), Acaderitic Press, New York
65. Gomi K., Iimura Y., and Hara S. Integrative transformation of Aspergillus oryzae with a plasmid containing the Aspergillus nidulans argB gene. Agric Biol Chem 51 (1987) 2549-2555
66. Gomi K., Kitamoto K., and Kumagai C. Transformation of the industrial strain of Aspergillus oryzae with the homologous amdS gene as a dominant selectable marker. J Ferment Technol 74 (1992) 389-391
67. Goto T., Wicklow D.T., and Ito Y. Aflatoxin and cyclopiazonic acid production by sclerotium-producing Aspergillus tamarii strain. Appl Environ Microbiol 62 (1996) 4036-4038
68. Gross C., Kelleher M., Vyer V.R., Brown P.O., and Winge D.R. Identification of copper regulation of Saccharomyces cerevisiae by DNA microarrays. J Biol Chem 275 (2000) 32310-32316
69. Hagiwara H., Kunihiro S., Nakajima K., Sano M., Masaki H., Yamamoto M., Pak J.W., Zhang Y., Takase K., Kuwabara I., Maruyama I.N., and Machida M. Affinity selection of DNA-binding proteins from yeast genomic DNA libraries by improved lambda phage display vector. J Biochem (Tokyo) 132 (2002) 975-982
70. Hall A.J., and Wild C.P. Epidemiology of aflatoxin-related disease. In: Eaton D.L., and Groopman J.D. (Eds). The Toxicology of Aflatoxins: Human Health, Veterinary, and Agricultural Significance (1994), Academic Press, San Diego 233-258
71. Hall L.A., and Denning D.W. Oxygen requirements of Aspergillus species. J Med Microbiol 41 (1994) 311-315
72. Harris L.J., Desjardins A.E., Plattner R.D., Nicholson P., Butler G., Young J.C., Weston G., Proctor R.H., and Hohn T.M. Possible role of trichothecene mycotoxins in virulence of Fusarium graminearum on maize. Plant Dis 83 (1999) 954-960
73. Hata Y., Kitamoto K., Gomi K., Kumagai C., and Tamura G. Functional elements of the promoter region of the Aspergillus oryzae glaA gene encoding glucoamylase. Curr Genet 22 (1992) 85-91
74. Hatamoto O, Matsushima K, Takahashi O, Umitsuki G, and Abe K (1999a) Modification of genome target site of multinucleated cell,targeting vector used thereof and modified multinucleated cell. In patent #: JP19990228915.
75. Hatamoto O., Sekine H., Nakano E., and Abe K. Cloning and expression of a cDNA encoding the laccase from Schizophyllum commune. Biosci Biotechnol Biochem 63 (1999) 58-64
76. Howard P.C., Eppley R.M., Stack M.E., Warbritton A., Voss K.A., Lorentzen R.J., Kovach R.M., and Bucci T.J. Fumonisin Blcarcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. Environ Health Perspect 109 S2 (2001) 277-282
77. Huang X., and Madan A. CAP3: A DNA sequence assembly program. Genome Res 9 (1999) 868-877
78. Iimura Y., Gomi K., Uzu H., and Hara S. Transformation of Aspergillus oryzae through plasmid-mediated complementation of the methionine-auxotrophic mutation. Agric Biol Chem 51 (1987) 323-328
79. Keller N.P., Cleveland T.E., and Bhatnagar D. Variable electrophoretic karyotypes of members of Aspergillus section Flavi. Curr Genet 21 (1992) 371-375
80. Keller N.P., and Hohn T.M. Metabolic pathway gene clusters in filamentous fungi. Fungal Genet Biol 21 (1997) 17-29
81. Kimura M., Matsumoto G., Shingu Y., Yoneyama K., and Yamaguchi I. The mystery of the trichothecene 3-O-acetyltransferase gene. Analysis of the region around Tri101 andcharacterization of its homologue from Fusarium sporotrichioides. FEBS Lett 435 (1998) 163-168
82. Kitamoto K., Kimura K., Gomi K., and Kumagai C. Electrophoretic karyotype and gene assignment to chromosomes of Aspergillus oryzae. Biosci Biotechnol Biochem 58 (1994) 1467-1470
83. Klich M.A., Mullaney E.J., Daly C.B., and Cary J.W. Molecular and physiological aspects of aflatoxin and sterigmatocystin biosynthesis by Aspergillus tamarii and A. ochraceoroseus. Appl Microbiol Biotechnol 53 (2000) 605-609
84. Kubodera T., Yamashita N., and Nishimura A. Pyrithiamine resistance gene (ptrA) of Aspergillus oryzae: cloning, characterization and application as a dominant selectable marker for transformation. Biosci Biotechnol Biochem 64 (2000) 1416-1421
85. Lancaster M.D., Jenkins F.P., and Philip J.M. Toxicity associated with certain samples of groundnuts. Nature 192 (1961) 1095-1096
86. Latgé J.P. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev 12 (1999) 310-350
87. Lee T., Han Y.-K., Kim K.-H., Yun S.-H., and Lee Y.-W. Tri13 and Tri7 determine deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae. Appl Environ Microbiol 68 (2002) 2148-2154
88. Machida M. Progress of Aspergillus genomics. In: Laskin A.I., Bennett J.W., and Gadd G.M. (Eds). Advances in Applied Microbiology 51 (2002), Academic Press, New York 81-106
89. Maertens J., Raad I., Sable C.A., Ngai A., Berman R., Patterson T.F., Denning D.W., and Walsh T. Multicenter, non-comparative study to evaluate safety and efficacy of caspofimgin (CAS) in adults with invasiveaspergillosis refractory or intolerant to amphotericin B, AMB lipid formulations or azoles. Interscience Conference on Antimicrobial Agents and Chemotherapy (2000)
90. Marahiel M.A., Stachelhaus T., and Mootz H.D. Modular peptide synthetases involved in nonribosomal peptide synthesis. Chem Rev 97 (1997) 2651-2673
91. Marasas W. Discovery and occurrence of the fumonisins:a historical perspective. Environ Health Perspect 109 S2 (2001) 239-243
92. McCormick S.P., and Alexander N.J. Fusarium Tri8 encodes a trichothecene C-3 esterase. Appl Environ Microbiol 68 (2002) 2959-2964
93. McCormick S.P., Alexander N.J., Trapp S.E., and Hohn T.M. Disruption of TRI101, the gene encoding trichothecene 3-O-acetyltransferase, from Fusarium sporotrichioides. Appl Environ Microbiol 65 (1999) 5252-5256
94. Meyers D.M., Obrian G., Du W.L., Bhatnagar D., and Payne G.A. Characterization of aflJ, a gene required for conversion of pathway intermediates to aflatoxin. Appl Environ Microbiol 64 (1998) 3713-3717
95. Minto R.E., and Townsend C.A. Enzymology and molecular biology of aflatoxin biosynthesis. Chem Rev 97 (1997) 2537-2555
96. Moore C.B., Sayers N., Mosquero J., Slaven J., and Denning D.W. Antifungal drug resistance in Aspergillus. J Infection 41 (2000) 203-220
97. Moss M.O. Mycotoxins of Aspergillus and other filamentous fungi. Soc. Appl Bacteriol Symp Ser 18 (1989) 69S-87S
98. Munkvold G.P., and Desjardins A.E. Fumonisins in maize: can we reduce their occurrence?. Plant Dis 81 (1997) 556-565
99. Nakajima K., Kunihiro S., Sano M., Zhang Y., Eto S., Chang Y.C., Suzuki T., Jigami Y., and Machida M. Comprehensive cloning and expression analysis of glycolytic genes from the filamentous fungus, Aspergillus oryzae. Curr Genet 37 (2000) 322-327
100. Nelson P.E., Desjardins A.E., and Plattner R.D. Fumonisins, mycotoxins produced by Fusarium species: biology, chemistry, and significance. Annu Rev Phytopathol 31 (1993) 233-252
101. Ng T.T.C., Robson G.D., and Denning D.W. Hydrocortisone-enhanced growth of Aspergillus spp: implications for pathogenesis. Microbiol 140 (1994) 2475-2480
102. O'Brian G.R., and Payne G.A. Identification of differentially expressed genes during aflatoxin biosynthesis in Aspergillus flavus. Proceedings of the 21st Fungal Genetics Conference. Asilomar, California (abs) (2001)
103. Pasamontes L., Haiker M., Wyss M., Tessier M., and van L.A. Gene cloning, purification, and characterization of a heat-stable phytase from the fungus Aspergillus fumigatus. Appl Environ Microbiol 63 (1997) 1696-1700
104. Payne G.A., Nystrom G.J., Bhatnagar D., Cleveland T.E., and Woloshuk C.P. Cloning of the afl-2 gene involved in aflatoxin biosynthesis from Aspergillus flavus. Appl Environ Microbiol 59 (1993) 156-162
105. Payne G.A. Process of contamination by aflatoxin-producing fungi and their impacts on crops. In: Sinha K.K., and Bhatnagar D. (Eds). Mycotoxins in Agriculture and Food Safety (1998), Marcel Dekker, New York 279-306
106. Payne G.A., and Brown M.P. Genetics and physiology of aflatoxin biosynthesis. Annu Rev Phytopathol 36 (1998) 329-362
107. rd Fumonisin Elimination and 15th Aflatoxin Elimination Workshops. San Antonio, Texas (abs) (2002)
108. Pitt J.I., Samson R.A., and Frisvad J.C. List of accepted species and their synonyms in the family Trichocomaceae. In: Samson R.A., and Pitt J.I. (Eds). Integration of modern taxonomic methods for Penicillium and Aspergillus classification (2000), Harwood Publishers, Amsterdam 9-49
109. Ponikau J.U., Sherris D.A., Kern E.B., Homburger H.A., Frigas E., Gaffey T.A., and Roberts G.D. The diagnosis and incidence of allergic fungal sinusitis. Mayo Clin Proc 74 (1999) 877-884
110. Pontecorvo G., Roper J.A., Hemmons L.M., Macdonald K.D., and Bufton A. The genetics of Aspergillus nidulans. Adv Genet 5 (1952) 141-238
111. Proctor R.H., Hohn T.M., McCormick S.P., and Desjardins A.E. TR16 encodes an unusual zinc finger protein involved in regulation of trichothecene biosynthesis in Fusarium sporotrichioides. Appl Environ Microbiol 61 (1995) 1923-1930
112. Proctor R.H., Desjardins A.E., Plattner R.D., and Hohn T.M. A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fukiuroi mating population A. Fungal Genet Biol 27 (1999) 100-112
113. Proctor R.H., Brown D.W., Plattner R.D., and Desjardins A.E. Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis. Fungal Genet Biol 38 (2003) 237-249
114. Pusateri A.E., and Kenison D.C. Measurement of zeranol in plasma from three blood vessels in steers implanted with zeranol. J Anim Sci 71 (1993) 415-419
115. Rankin N.E. Disseminated aspergillosis and moniliasis associated with agranulocytosis and antibiotic therapy. Br Med J 25 (1953) 918-919
116. Ruiter-Jacobs Y.M., Broekhuijsen M., Unkles S.E., Campbell E., Kinghorn J.R., Contreras R., Pouwels P.H., and van d.H.C. A gene transfer system based on the homologous pyrG gene and efficient expression of bacterial genes in Aspergillus oryzae. Curr Genet 16 (1989) 159-163
117. Sano M., Ohyama A., Takase K., Yamamoto M., and Machida M. Electrophoretic mobility shift scanning using an automated infrared DNA sequencer. Biotechniques 31 (2001) 1056-1058
118. Sano M., Ohyama A., Takase K., Yamamoto M., and Machida M. Electrophoretic mobility shift scanning using an automated infrared DNA sequencer. Biotechniques 31 (2001) 1060, 1062
119. Seo J.-A., Proctor R.H., and Plattner R.D. Characterization of four clustered and coregulated genes associated with fumonisin biosynthesis in Fusarium verticillioides. Fungal Genet Biol 34 (2001) 155-165
120. Sharma R.P., and Kim Y.-W. In: Sharma R.P., and Salunkhe D.K. (Eds). Mycotoxins and Phytoalexins (1991), CRC Press, Boca Raton 339-359
121. Sharma R.P., and Salunkhe D.K. Mycotoxin and Phytoalexins in Human and Animal Health (1991), CRC Press, Boca Raton
122. Shim W.-B., and Woloshuk C.P. Regulation of fumonisin Bl biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1. Appl Environ Microbiol 67 (2001) 1607-1612
123. Skory C.D., Chang P.-K., Cary J., and Linz J.E. Isolation and characterization of a gene from Aspergillus parasiticus associated with the conversion of versicolorin A to sterigmatocystin in aflatoxin biosynthesis. Appl Environ Microbiol 58 (1992) 3527-3537
124. Soares M.B., Bonaldo M.F., Jelene P., Su L., Lawton L., and Efstratiadis A. Construction and characterization of a normalized cDNA library. Proc Natl Acad Sci USA 91 (1994) 9228-9232
125. Squire R.A. Ranking animal carcinogens: a proposed regulatory approach. Science 214 (1989) 887-891
126. Stevens D.A., Schwartz H.J., Lee J.Y., Moskovitz B.L., Jerome D.C., Catanzaro A., Bamberger D.M., Weinmann A.J., Tuazon C.U., Judson M.A., Platts-Mills T.A., and DeGraff Jr. A.C. A randomized trial of itraconazole in allergic bronchopulmonary aspergillosis. N Engl J Med 342 (2000) 756-762
127. Tag A.G., Garifullina G.F., Peplow A.W., Ake Jr. C., Phillips T.D., Hohn T.M., and Beremand M.N. A novel regulatory gene, Tri10, controls trichothecene toxin production and gene expression. Appl Environ Microbiol 67 (2001) 5294-5302
128. Tailor M.J., and Richardson T. Applications of microbial enzymes in food systems and in biotechnology. Adv Appl Microbiol 25 (1979) 7-35
129. Timberlake W.E. Molecular genetics of Aspergillus development. Annu Rev Genet 24 (1990) 5-36
130. Townsend C.A. Progress towards a biosynthetic rationale of the aflatoxin pathway. Pure Appl Chem 58 (1997) 227-238
131. Tudzynski B. Biosynthesis of gibberellins in Gibberellafujikuroi: biomolecular aspects. Appl Microbiol Biotechnol 52 (2002) 298-310
132. Unkles S.E., Campbell E., Ruiter-Jacobs Y.M., Broekhuijsen M., Macro J.A., Carrez D., Contreras R., van d.H.C., and Kinghorn J.R. The development of a homologous transformation system for Aspergillus oryzae based on the nitrate assimilation pathway:A convenient and general selection system for filamentous fungal transformation. Mol Gen Genet 218 (1989) 99-104
133. Ushijima S., and Nakadai T. Breeding by protoplast fusion of koji mold Aspergillus sojae. Agric Biol Chem 51 (1987) 1051-1057
134. Ushijima S., Nakadai T., and Uchida K. Breeding of new koji-molds through interspecific hybridization between Aspergillus oryzae and Aspergillus sojae by protoplast fusion. Agric Biol Chem 54 (1990) 1667-1676
135. Van E.H. Current situation on regulations for mycotoxins: Overview of tolerances and status of standard methods of sampling and analysis. Food Addit Contam 6 (1989) 134-188
136. th European Conference on Fungal Genetics. Pisa, Italy (2002)
137. Verdoes J.C., Calil M.R., Punt P.J., Debets F., Swart K., Stouthamer A.H., and van d.H.C. The complete karyotype of Aspergillus niger: the use of introduced electrophoretic mobility variation of chromosomes for gene assignment studies. Mol Gen Genet 244 (1994) 75-80
138. Wang E., Norred W.P., Bacon C.W., Riley R.T., and Merrill Jr. A.H. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J Biol Chem 266 (1991) 14486-14490
139. Woloshuk C.P., Foutz K.R., Brewer J.F., Bhatnagar D., Cleveland T.E., and Payne G.A. Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis. Appl Environ Microbiol 60 (1994) 2408-2414
140. Wu T.S., and Linz J.E. Recombinational inactivation of the gene encoding nitrate reductase in Aspergillus parasiticus. Appl Environ Microbiol 59 (1993) 2998-3002
141. Yabe K., Matsushima K., Koyama T., and Hamasaki T. Purification and characterization of O-methyltransferase I involved in conversion of demethylsterigmatocystin tosterigmatocystin and of dihydrodemethylsterigmatocystin to dihydrosterigmatocystin during aflatoxin biosynthesis. Appl Environ Microbiol 64 (1998) 166-171
142. Yu J., Cary J.W., Bhatnagar D., Cleveland T.E., Keller N.P., and Chu F.S. Cloning and characterization of a cDNA from Aspergillus parasiticus encoding an O-methyltransferase involved in aflatoxin biosynthesis. Appl Environ Microbiol 59 (1993) 3564-3571
143. Yu J., Chang P.-K., Cary J.W., Wright M., Bhatnagar D., Cleveland T.E., Payne G.A., and Linz J.E. Comparative mapping of aflatoxin pathway gene clusters in Aspergillus parasiticus and Aspergillus flavus. Appl Environ Microbiol 61 6 (1995) 2365-2371
144. Yu J., Chang P.-K., Payne G.A., Cary J.W., Bhatnagar D., and Cleveland T.E. Comparison of the omtA genes encoding O-methyltransferases involved in aflatoxin biosynthesis from Aspergillus parasiticus and A. flavus. Gene 163 (1995) 121-125
145. Yu J., Chang P.-K., Cary J.W., Bhatnagar D., and Cleveland T.E. avnA, a gene encoding a cytochrome P-450 monooxygenase is involved in the conversion of averantin to averufin in aflatoxin biosynthesis in Aspergillus parasiticus. Appl Environ Microbiol 63 (1997) 1349-1356
146. 2 biosynthesis. Appl Environ Microbiol 64 (1998) 4834-4841
147. nd ed. (2003), Marcel Dekker, New York
148. Yu J., Chang P.-K., Bhatnagar D., and Cleveland T.E. Genes encoding cytochrome P450 and monooxigenase enzymes define one end of the aflatoxin pathway gene cluster in Aspergillus parasiticus. Appl Microbiol Biotechnol 53 (2000) 583-590
149. Yu J., Woloshuk C.P., Bhatnagar D., and Cleveland T.E. Cloning and characterization of avfA and omtB genes involved in aflatoxin biosynthesis in three Aspergillus species. Gene 248 (2000) 157-167
150. (Special Issue). Yu J., Bhatnagar D., and Cleveland T.E. Aspergillus flavus genomics for elimination of aflatoxin contamination. Mycopathologia 155 (2002) 10
151. (Special Issue). Yu J., Bhatnagar D., Cleveland T.E., and Nierman W.C. Aspergillus flavus EST technology and its applications for eliminating aflatoxin contamination. Mycopathologia 155 (2002) 6
152. th Aflatoxin Elimination Workshops. San Antonio, Texas. (Abs) (2002)
153. Yu J., Bhatnagar D., and Ehrlich K.C. Aflatoxin Biosynthesis. Rev Iberoam Microl (RIAM), Spain 19 (2002) 191-200
154. Yu J.-H., Butchko R.A., Fernandes M., Keller N.P., Leonard T.J., and Adams T.H. Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus. Curr Genet 29 (1996) 549-555
155. Zhang Y., Pak J.W., Maruyama I.N., and Machida M. Affinity selection of DNA-binding proteins displayed on bacteriophage lambda. J Biochem 127 (2000) 1057-1063