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Volumn 79, Issue 1, 2008, Pages 47-59

Therapy of cognitive deficits in schizophrenia with acetylcholinesterase inhibitors. A systematic overview;Therapie kognitiver defizite durch AChE-hemmer bei patienten mit schizophrenie. Eine systematische übersicht

Author keywords

Acetylcholinesterase inhibitors; Cholinergic system; Cognitive deficits; Schizophrenia

Indexed keywords

CHOLINESTERASE INHIBITOR; DONEPEZIL; GALANTAMINE; MUSCARINIC RECEPTOR; NEUROLEPTIC AGENT; NICOTINIC RECEPTOR; PHYSOSTIGMINE; RIVASTIGMINE;

EID: 38349170971     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-007-2358-1     Document Type: Review
Times cited : (10)

References (90)
  • 1
    • 0032966073 scopus 로고    scopus 로고
    • Addington J, Addington D (1999) Neurocognitive and social functioning in schizophrenia. Schizophr Bull 25: 173-182
    • (1999) Schizophr Bull , vol.25 , pp. 173
    • Addington1
  • 2
    • 0027380988 scopus 로고
    • Adler LE, Hoffer LD, Wiser A et al. (1993) Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am J Psychiatry 150: 1856-1861
    • (1993) Am J Psychiatry , vol.150 , pp. 1856
    • Adler1
  • 3
    • 7544251500 scopus 로고    scopus 로고
    • Bilder RM, Goldman RS, Robinson D et al. (2000) Neuropsychology of first-episode schizophrenia: initial characterization and clinical correlates. Am J Psychiatry 157: 549-559
    • (2000) Am J Psychiatry , vol.157 , pp. 549
    • Bilder1
  • 4
    • 21544484299 scopus 로고    scopus 로고
    • Bora E, Veznedaroglu B, Kayahan B (2005) The effect of galantamine added to clozapine on cognition of five patients with schizophrenia. Clin Neuropharmacol 28: 139-141
    • (2005) Clin Neuropharmacol , vol.28 , pp. 139
    • Bora1
  • 5
    • 0033832470 scopus 로고    scopus 로고
    • Breese CR, Lee MJ, Adams CE et al. (2000) Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia. Neuropsychopharmacology 23: 351-364
    • (2000) Neuropsychopharmacology , vol.23 , pp. 351
    • Breese1
  • 6
    • 0037209930 scopus 로고    scopus 로고
    • Buchanan RW, Summerfeld A, Tek C, Gold J (2001) An open-labeled trial of adjunctive donepezil for cognitive impairments in patients with schizophrenia. Schizophr Res 59: 29-33
    • (2001) Schizophr Res , vol.59 , pp. 29
    • Buchanan1
  • 7
    • 0037604627 scopus 로고    scopus 로고
    • Bymaster FP, Felder C, Ahmed S, McKinzie D (2002) Muscarinic receptors as a target for drugs treating schizophrenia. Curr Drug Targets CNS Neurol Disord 1: 163-181
    • (2002) Curr Drug Targets CNS Neurol Disord , vol.1 , pp. 163
    • Bymaster1
  • 8
    • 0033935478 scopus 로고    scopus 로고
    • Cannon TD, Bearden CE, Hollister JM et al. (2000) Childhood cognitive functioning in schizophrenia patients and their unaffected siblings: a prospective cohort study. Schizophr Bull 26: 379-393
    • (2000) Schizophr Bull , vol.26 , pp. 379
    • Cannon1
  • 9
    • 0038474159 scopus 로고    scopus 로고
    • Callicott JH, Egan MF, Mattay VS et al. (2003) Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia. Am J Psychiatry 160: 709-719
    • (2003) Am J Psychiatry , vol.160 , pp. 709
    • Callicott1
  • 10
    • 0031708881 scopus 로고    scopus 로고
    • Chen WJ, Liu SK, Chang CJ et al. (1998) Sustained attention deficit and schizotypal personality features in nonpsychotic relatives of schizophrenic patients. Am J Psychiatry 155: 1214-1220
    • (1998) Am J Psychiatry , vol.155 , pp. 1214
    • Chen1
  • 11
    • 0034975130 scopus 로고    scopus 로고
    • Crook JM, Tomaskovic-Crook E, Copolov DL, Dean B (2001) Decreased muscarinic receptor binding in prefrontal cortex from subjects with schizophrenia: A study of Brodmann's areas 8,9,10 and 46 and the effects of neuroleptic drug treatment. Am J Psychiatry 158: 918-925
    • (2001) Am J Psychiatry , vol.158 , pp. 918
    • Crook1
  • 12
    • 0033980910 scopus 로고    scopus 로고
    • Cummings JL (2000) Cholinesterase inhibitors: A new class of psychotropic compounds. Am J Psychiatry 157: 4-15
    • (2000) Am J Psychiatry , vol.157 , pp. 4
    • Cummings1
  • 13
    • 0018147740 scopus 로고
    • Davis KL, Mohs RC, Tinklenberg JR et al. (1978) Physostigmine: improvement of long-term memory processes in normal humans. Science 201: 272-274
    • (1978) Science , vol.201 , pp. 272
    • Davis1
  • 14
    • 23844528477 scopus 로고    scopus 로고
    • Deutsch SI, Rosse RB, Schwartz BL et al. (2005) Therapeutic implications of a selective alpha7 nicotinic receptor abnormality in schizophrenia. Isr J Psychiatry Relat Sci 42: 33-44
    • (2005) Isr J Psychiatry Relat Sci , vol.42 , pp. 33
    • Deutsch1
  • 15
    • 33748138102 scopus 로고    scopus 로고
    • Dickerson B (2006) Functional magnetic resonance imaging of cholinergic modulation in mild cognitive impairment. Curr Opin Psychiatry 19: 229-306
    • (2006) Curr Opin Psychiatry , vol.19 , pp. 229
    • Dickerson1
  • 16
    • 0141669337 scopus 로고    scopus 로고
    • Eberhard J, Riley F, Levander S (2003) Premorbid IQ and schizophrenia. Increasing cognitive reduction by episodes. Eur Arch Psychiatry Clin Neurosci 253: 84-88
    • (2003) Eur Arch Psychiatry Clin Neurosci , vol.253 , pp. 84
    • Eberhard1
  • 17
    • 0034351614 scopus 로고    scopus 로고
    • Freedman R, Adams CE, Leonard S (2000) The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. J Chem Neuroanat 20: 299-306
    • (2000) J Chem Neuroanat , vol.20 , pp. 299
    • Freedman1
  • 18
    • 0029085870 scopus 로고
    • Freedman R, Hall M, Adler LE, Leonard S (1995) Evidence in post-mortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry 38: 22-33
    • (1995) Biol Psychiatry , vol.38 , pp. 22
    • Freedman1
  • 19
    • 27144510114 scopus 로고    scopus 로고
    • Freudenreich O, Herz L, Deckersbach T et al. (2005) Added donepezil for stable schizophrenia: a double-blind pacebo-controlled trial. Psychopharmacology 181: 358-363
    • (2005) Psychopharmacology , vol.181 , pp. 358
    • Freudenreich1
  • 20
    • 3142746642 scopus 로고    scopus 로고
    • Friedman JI (2004) Cholinergic targets for cognitive enhancement in schizophrenia: focus on cholinesterase inhibitors and muscarinic agonists. Psychopharmacology 174: 45-53
    • (2004) Psychopharmacology , vol.174 , pp. 45
    • Friedman1
  • 21
    • 0036501411 scopus 로고    scopus 로고
    • Friedman JI, Adler DN, Howanitz E et al. (2002) A double blind placebo controlled trial of donepezil adjunctive treatment to risperidone for the cognitive impairment of schizophrenia. Biol Psychiatry 51: 349-357
    • (2002) Biol Psychiatry , vol.51 , pp. 349
    • Friedman1
  • 22
    • 0034704207 scopus 로고    scopus 로고
    • Furey ML, Pietrini P, Haxby JV (2000) Cholinergic enhancement and increased selectivity of perceptual processing during working memory. Science 290: 2315-2319
    • (2000) Science , vol.290 , pp. 2315
    • Furey1
  • 23
    • 0028080244 scopus 로고
    • Grimm U, Moser U, Mutschler E, Lambrecht G (1994) Muscarinic receptors: focus on presynaptic mechanisms and recently developed novel agonists and antagonists. Pharmazie 49: 711-726
    • (1994) Pharmazie , vol.49 , pp. 711
    • Grimm1
  • 24
    • 0032860930 scopus 로고    scopus 로고
    • Gold S, Arndt S, Nopoulos P et al. (1999) Longitudinal study of cognitive function in first-episode and recent-onset schizophrenia. Am J Psychiatry 156: 1342-1348
    • (1999) Am J Psychiatry , vol.156 , pp. 1342
    • Gold1
  • 25
    • 2942683373 scopus 로고    scopus 로고
    • Harris JG, Kongs S, Allensworth D et al. (2004) Effects of nicotine on cognitive defizits in schizophrenia. Neuropsychopharmacology 29: 1378-1385
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1378
    • Harris1
  • 26
    • 0035140610 scopus 로고    scopus 로고
    • Harvey PD, Keefe RS (2001) Studies of cognitive change in ptients with schizophrenia following novel antipsychotic treatment. Am J Psychiatry 158: 176-184
    • (2001) Am J Psychiatry , vol.158 , pp. 176
    • Harvey1
  • 27
    • 0031903740 scopus 로고    scopus 로고
    • Heinrichs RW, Zakzanis KK (1998) Neurocognitive deficits in schizophrenia: A quantitative review of the evidence. Neuropsychology 12: 426-445
    • (1998) Neuropsychology , vol.12 , pp. 426
    • Heinrichs1
  • 28
    • 33748165141 scopus 로고    scopus 로고
    • Heydebrand G (2006) Cognitive deficits in the families of patients with schizophrenia. Curr Opin Psychiatry 19: 227-281
    • (2006) Curr Opin Psychiatry , vol.19 , pp. 227
    • Heydebrand1
  • 29
    • 0026735244 scopus 로고
    • Hoff AL, Riordan H, O'Donnell DW et al. (1992) Neuropsychological functioning of first-episode schizophreniform patients. Am J Psychiatry 149: 898-903
    • (1992) Am J Psychiatry , vol.149 , pp. 898
    • Hoff1
  • 30
    • 0032858515 scopus 로고    scopus 로고
    • Hoff AL, Sakuma M, Wieneke M et al. (1999) Longitudinal neuropsychological follow-up study of patients with first-episode schizophrenia. Am J Psychiatry 156: 1336-1341
    • (1999) Am J Psychiatry , vol.156 , pp. 1336
    • Hoff1
  • 31
    • 0242367566 scopus 로고    scopus 로고
    • Hogg RC, Raggenbass M, Bertrand D (2003) Nicotinic acetylcholine receptors: from structure to brain function. Rev Physiol Biochem Pharmacol 147: 1-46
    • (2003) Rev Physiol Biochem Pharmacol , vol.147 , pp. 1
    • Hogg1
  • 32
    • 0022507410 scopus 로고
    • Hughes JR, Hatsukami KD, Mitchell JE et al. (1986) Prevalence of smoking among psychiatric outpatients. Am J Psychiatry 152: 993-997
    • (1986) Am J Psychiatry , vol.152 , pp. 993
    • Hughes1
  • 33
    • 0031978625 scopus 로고    scopus 로고
    • Hutton SB, Puri BK, Duncon LJ et al. (1998) Executive function in first-episoed schizophrenia. Psychol Med 28: 463-473
    • (1998) Psychol Med , vol.28 , pp. 463
    • Hutton1
  • 34
    • 0034934938 scopus 로고    scopus 로고
    • Hyde TM, Crook JM (2001) Cholinergic systems and schizophrenia: primary pathology or epiphenoma? J Chem Neuroanat 22: 53-63
    • (2001) J Chem Neuroanat , vol.22 , pp. 53
    • Hyde1
  • 35
    • 0036176263 scopus 로고    scopus 로고
    • Ichikawa J, Dai J, O'Laughlin A et al. (2002) Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum. Neuropsychopharmacology 26: 325-339
    • (2002) Neuropsychopharmacology , vol.26 , pp. 325
    • Ichikawa1
  • 36
    • 9644278029 scopus 로고    scopus 로고
    • Jann MW (2004) Implications for atypical antipsychotics in the treatment of schizophrenia: neurocognition effects and a neuroprotective hypothesis. Pharmacotherapy 24: 1759-1783
    • (2004) Pharmacotherapy , vol.24 , pp. 1759
    • Jann1
  • 37
    • 0030445548 scopus 로고    scopus 로고
    • Karson CN, Mrak RE, Husain MM, Griffin WS (1996) Decreased mesopontine choline acetyltransferase levels in schizophrenia. Correlations with cognitive functions. Mol Chem Neuropathol 29: 181-191
    • (1996) Mol Chem Neuropathol , vol.29 , pp. 181
    • Karson1
  • 38
    • 0033021909 scopus 로고    scopus 로고
    • Keefe SE, Silva SG, Perkins DO, Lieberman JA (1999) The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: a review an meta-analysis. Schizophr Bull 25: 201-222
    • (1999) Schizophr Bull , vol.25 , pp. 201
    • Keefe1
  • 39
    • 29144532017 scopus 로고    scopus 로고
    • Keefe RS, Young CA, Rock SL et al. HGGN Study Group (2006) One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia. Schizophr Res 81: 1-15
    • (2006) Schizophr Res , vol.81 , pp. 1
    • Keefe1
  • 40
    • 2942565924 scopus 로고    scopus 로고
    • Keefe SE, Seidman LJ, Christensen BK et al. (2004) Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: A randomized double-blind trial of Olanzapine versus low doses of Haloperidol. Am J Psychiatry 161: 985-995
    • (2004) Am J Psychiatry , vol.161 , pp. 985
    • Keefe1
  • 41
    • 3242813609 scopus 로고    scopus 로고
    • Keri S, Janka Z (2004) Critical evaluation of cognitive dysfunctions as endophenotypes of schizophrenia. Acta Psychiatr Scand 110: 83-91
    • (2004) Acta Psychiatr Scand , vol.110 , pp. 83
    • Keri1
  • 42
    • 0035281005 scopus 로고    scopus 로고
    • Kirrane RM, Mitropoulou V, Nunn M et al. (2001) Physostigmine and cognition in schizotypal personality disorder. Schizophr Res 48: 1-5
    • (2001) Schizophr Res , vol.48 , pp. 1
    • Kirrane1
  • 43
    • 0038690569 scopus 로고    scopus 로고
    • Kitawaga H, Takenouchi T, Azuma R et al. (2003) Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers. Neuropsychopharmacology 28: 542-551
    • (2003) Neuropsychopharmacology , vol.28 , pp. 542
    • Kitawaga1
  • 44
    • 13444271974 scopus 로고    scopus 로고
    • Kivircik Akdede BB, Alptekin K, Kitis A et al. (2004) Effects of quetiapine on cognitive functions in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 29: 233-238
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 233
    • Kivircik1
  • 45
    • 9244231114 scopus 로고    scopus 로고
    • Lenzi A, Tuscano D (2004) Do Acetylcholinesterase inhibitors have a role in improving cognitive impairment in patients with schizophrenia? Int J Pharm Med 18: 139-148
    • (2004) Int J Pharm Med , vol.18 , pp. 139
    • Lenzi1
  • 46
    • 0344306578 scopus 로고    scopus 로고
    • Lenzi A, Maltini E, Poggi E et al. (2003) Effects of rivastigmine on cognitive function and quality of life in patients with schizophrenia. Clin Neuropharmacol 6: 317-321
    • (2003) Clin Neuropharmacol , vol.6 , pp. 317
    • Lenzi1
  • 47
    • 0036890828 scopus 로고    scopus 로고
    • Levin ED (2002) Nicotinic receptor subtypes and cognitive function. J Neurobiol 53: 633-640
    • (2002) J Neurobiol , vol.53 , pp. 633
    • Levin1
  • 48
    • 32844461888 scopus 로고    scopus 로고
    • Levin ED, McClernon FJ, Rezvani AH (2006) Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization. Psychopharmacology 184: 523-539
    • (2006) Psychopharmacology , vol.184 , pp. 523
    • Levin1
  • 49
    • 9544223172 scopus 로고    scopus 로고
    • Lewin JS, Friedman L, Wu D et al. (1996) Cortical localization of human sustained attention: detection with functional MR using a visual vigilance paradigm. J Comput Assist Tomogr 20: 695-701
    • (1996) J Comput Assist Tomogr , vol.20 , pp. 695
    • Lewin1
  • 50
    • 0027431913 scopus 로고
    • Malhotra AK, Litman RE, Pickar D (1993) Adverse effects of antipsychotic drugs. Drug Saf 9: 429-436
    • (1993) Drug Saf , vol.9 , pp. 429
    • Malhotra1
  • 51
    • 32844456907 scopus 로고    scopus 로고
    • Mansvelder HD, Aerde KI van, Couey JJ, Brussaard AB (2006) Nicotinic modulation of neural networks: from receptors to cognition. Psychopharmacology 184: 292-305
    • (2006) Psychopharmacology , vol.184 , pp. 292
    • Mansvelder1
  • 52
    • 3142761435 scopus 로고    scopus 로고
    • Martin LF, Kem WR, Freedman R (2004) Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia. Psychopharmacology 174: 54-64
    • (2004) Psychopharmacology , vol.174 , pp. 54
    • Martin1
  • 53
    • 4944260901 scopus 로고    scopus 로고
    • Medalia A, Lim RW (2004) Self-awareness of cognitive functioning in schizophrenia. Schizophr Res 71: 331-338
    • (2004) Schizophr Res , vol.71 , pp. 331
    • Medalia1
  • 54
    • 8644257717 scopus 로고    scopus 로고
    • Mendelsohn E, Rosenthal M, Bohiri Y et al. (2004) Rivastigmine augmentation in the management of chronic schizophrenia with comorbid dementia: an open-labeled study investigating effects on cognition, behaviour and activities of daily living. Int Clin Psychopharmacol 19: 319-324
    • (2004) Int Clin Psychopharmacol , vol.19 , pp. 319
    • Mendelsohn1
  • 55
    • 0032977410 scopus 로고    scopus 로고
    • Meltzer HY, McGurk SR (1999) The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr Bull 25: 233-255
    • (1999) Schizophr Bull , vol.25 , pp. 233
    • Meltzer1
  • 56
    • 2342475885 scopus 로고    scopus 로고
    • Mishara AL, Goldberg TE (2004) A meta-analysis and critical review of the effects of conventional neuroleptic treatment on cognition in schizophrenia: opening a closed book. Biol Psychiatry 55: 1013-1022
    • (2004) Biol Psychiatry , vol.55 , pp. 1013
    • Mishara1
  • 57
    • 0032811224 scopus 로고    scopus 로고
    • Mohamed S, Paulsen JS, O'Leary D et al. (1999) Generalized cognitive deficits in schizophrenia: a study of first-episode patients. Arch Gen Psychiatry 56: 749-754
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 749
    • Mohamed1
  • 58
    • 33845333413 scopus 로고    scopus 로고
    • Morrison G, O'Carroll R, McCreadie R (2006) Long-term course of cognitive impairment in schizophrenia. Br J Psychiatry 189: 556-557
    • (2006) Br J Psychiatry , vol.189 , pp. 556
    • Morrison1
  • 59
    • 0042591639 scopus 로고    scopus 로고
    • Nahas Z, George MS, Horner MD et al. (2003) Augmenting atypical antipsychotics with a cognitive enhancer (donepezil) improves regional brain activity in schizophrenia patients: a pilot double-blind placebo controlled BOLD fMRI study. Neurocase 9: 274-282
    • (2003) Neurocase , vol.9 , pp. 274
    • Nahas1
  • 60
    • 25444500137 scopus 로고    scopus 로고
    • Peuskens J, Demily C, Thibaut F (2005) Treatment of cognitive dysfunction in schizophrenia. Clin Ther 27: 25-37
    • (2005) Clin Ther , vol.27 , pp. 25
    • Peuskens1
  • 61
    • 0031846540 scopus 로고    scopus 로고
    • Powchik P, Davidson M, Haroutunian V et al. (1998) Postmortem studies in schizophrenia. Schizophr Bull 24: 325-341
    • (1998) Schizophr Bull , vol.24 , pp. 325
    • Powchik1
  • 62
    • 0034720816 scopus 로고    scopus 로고
    • Raskind MA, Perskind ER, Wessel T, Yuan W (2000) Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Neurology 54: 2261-2268
    • (2000) Neurology , vol.54 , pp. 2261
    • Raskind1
  • 63
    • 8844245878 scopus 로고    scopus 로고
    • Reyes JF, Preskorn SH, Khan A et al. (2004) Concurrent administration of donepezil HCI and risperidone in patients with schizophrenia: assessment of pharmacokinetic changes and safety following multiple oral doses. Br J Clin Pharmacol 58: 50-57
    • (2004) Br J Clin Pharmacol , vol.58 , pp. 50
    • Reyes1
  • 64
    • 0035251680 scopus 로고    scopus 로고
    • Rezvani AH, Levin ED (2001) Cognitive effects of nicotine. Biol Psychiatry 49: 258-267
    • (2001) Biol Psychiatry , vol.49 , pp. 258
    • Rezvani1
  • 65
    • 0034713327 scopus 로고    scopus 로고
    • Riley EM, McGovern D, Mockler D et al. (2000) Neuropsychological functioning in first-episode psychosis - evidence of specific deficits. Schizophr Res 43: 47-55
    • (2000) Schizophr Res , vol.43 , pp. 47
    • Riley1
  • 66
    • 3242678172 scopus 로고    scopus 로고
    • Ripoll N, Bronnec M, Bourin M (2004) Nicotinic receptors and schizophrenia. Curr Med Res Opin 20: 1057-1074
    • (2004) Curr Med Res Opin , vol.20 , pp. 1057
    • Ripoll1
  • 67
    • 0032507788 scopus 로고    scopus 로고
    • Rogers SL, Doody RS, Mohs RC, Friedhoff LT, Donepezil Study Group (1998) Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Arch Intern Med 158: 1021-1031
    • (1998) Arch Intern Med , vol.158 , pp. 1021
    • Rogers1
  • 68
    • 0033998977 scopus 로고    scopus 로고
    • Rogers SL, Doody RS, Pratt RD et al. (2000) Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: final analysis of US multicenter open-label study. Eur Neuropsychopharmacol 10: 195-203
    • (2000) Eur Neuropsychopharmacol , vol.10 , pp. 195
    • Rogers1
  • 69
    • 0036709356 scopus 로고    scopus 로고
    • Rosse BR, Deutsch SI (2002) Adjuvant Galantamine administration improves negative symptoms in a patient with treatment-refractory schizophrenia. Clin Neuropharmacol 25: 272-275
    • (2002) Clin Neuropharmacol , vol.25 , pp. 272
    • Rosse1
  • 70
    • 17744375473 scopus 로고    scopus 로고
    • Sacco KA, Termine A, Seyal A et al. (2005) Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: involvement of nicotinic receptor mechanisms. Arch Gen Psychiatry 62: 649-659
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 649
    • Sacco1
  • 71
    • 10744232323 scopus 로고    scopus 로고
    • Samochicki M, Höffle A, Fehrenbacher A et al. (2003) Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J Pharmacol Exp Ther 305: 1024-1036
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 1024
    • Samochicki1
  • 72
    • 0036232874 scopus 로고    scopus 로고
    • Santos MD, Alkondon M, Pereira EFR et al. (2002) The nicotinic allosteric potentiating ligand Galantamine facilitates synaptic transmission in the mammalian central nervous system. Mol Pharmacol 61: 1222-1234
    • (2002) Mol Pharmacol , vol.61 , pp. 1222
    • Santos1
  • 73
    • 33748751285 scopus 로고    scopus 로고
    • Schubert MH, Keith AY, Hicks PB (2006) Galantamine improves cognition in schizophrenic patients stabilized on Risperidone. Biol Psychiatry 60: 530-533
    • (2006) Biol Psychiatry , vol.60 , pp. 530
    • Schubert1
  • 74
    • 0027102729 scopus 로고
    • Schwartz JT, Brotman AW (1992) A clinical guide to antipsychotic drugs. Drugs 44: 981-992
    • (1992) Drugs , vol.44 , pp. 981
    • Schwartz1
  • 75
    • 0028144551 scopus 로고
    • Saykin AJ, Shtasel DL, Gur RE et al. (1994) Neuropsychological deficits in neuroleptic naïve patients with first-episode schizophrenia. Arch Gen Psychiatry 51: 124-131
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 124
    • Saykin1
  • 76
    • 33745378627 scopus 로고    scopus 로고
    • Sharma T, Reed C, Aasen I, Kumari V (2006) Cognitive effects of adjunctive 24-weeks Rivastigmine treatment to antipsychotics in schizophrenia: A randomized, placebo-controlled, double-blind investigation. Schizophr Res 85: 73-83
    • (2006) Schizophr Res , vol.85 , pp. 73
    • Sharma1
  • 77
    • 12344272531 scopus 로고    scopus 로고
    • Sing A, Potter A, Newhouse P (2004) Nicotinic acetylcholine receptor system and neuropsychiatric disorders. Drugs 7: 1096-1103
    • (2004) Drugs , vol.7 , pp. 1096
    • Sing1
  • 78
    • 0036711193 scopus 로고    scopus 로고
    • Smith RC, Singh A, Infante M et al. (2002) Effects of cigarette smoking and nicotine nasal spray on psychiatric symptoms and cognition in schizophrenia. Neuropsychopharmacology 27: 479-497
    • (2002) Neuropsychopharmacology , vol.27 , pp. 479
    • Smith1
  • 79
    • 13444283738 scopus 로고    scopus 로고
    • Stip E, Chouinard S, Boulay LJ (2005) On the trail of a cognitive enhancer for the treatment of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 29: 219-232
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 219
    • Stip1
  • 80
    • 28744457842 scopus 로고    scopus 로고
    • Stip E, Sepehry AA, Prouteau A et al. (2005) Cognitive discernible factors between schizophrenia and schizoaffective disorder. Brain Cogn 59: 292-295
    • (2005) Brain Cogn , vol.59 , pp. 292
    • Stip1
  • 81
    • 38349160257 scopus 로고    scopus 로고
    • Stirling J, White C, Lewis S et al. (2003) Neurocognitive function and outcome in first-episode schizophrenia: a 10-year follow up of an epidemiological cohort-sectional analysis. Psychiatry Res 121: 219-227
    • (2003) Psychiatry Res , vol.121 , pp. 219
    • Stirling1
  • 82
    • 0037262337 scopus 로고    scopus 로고
    • Stryjer R, Strous RD, Bar F et al. (2003) Beneficial effect of donepezil augmentation for the management of comorbid schizophrenia and dementia. Clin Neuropharmacol 26: 12-17
    • (2003) Clin Neuropharmacol , vol.26 , pp. 12
    • Stryjer1
  • 83
    • 0028007038 scopus 로고
    • Sullivan EV, Shear PK, Zipursky RB et al. (1994) A deficit profile of executive, memory and motor functions in schizophrenia. Biol Psychiatry 36: 641-653
    • (1994) Biol Psychiatry , vol.36 , pp. 641
    • Sullivan1
  • 84
    • 0026025726 scopus 로고
    • Tandon R, Shipley JE, Greden JG et al. (1991) Muscarinic cholinergic hyperactivity in schizophrenia: relationship to positive and negative symptoms. Schizophr Res 4: 23-30
    • (1991) Schizophr Res , vol.4 , pp. 23
    • Tandon1
  • 85
    • 0036886986 scopus 로고    scopus 로고
    • Tandon R (2002) Safety and tolerability: how do newer generation.,atypical" antipsychotics compare? Psychiatr Q 73: 297-311
    • (2002) Psychiatr Q , vol.73 , pp. 297
    • Tandon1
  • 86
    • 22744458115 scopus 로고    scopus 로고
    • Texido L, Ros E, Martin-Satue M et al. (2005) Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity. Br J Pharmacol 145: 672-678
    • (2005) Br J Pharmacol , vol.145 , pp. 672
    • Texido1
  • 87
    • 17544402307 scopus 로고    scopus 로고
    • Tugal Ö, Yazici KM, Yagcioglu AEA, Gögüs A (2004) A double-blind, placebo-controlled, cross-over trial of adjunctive donepezil for cognitive impairment in schizophrenia. Int J Neuropsychopharmacol 7: 117-123
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 117
    • Tugal1
  • 88
    • 0036790920 scopus 로고    scopus 로고
    • Turetsky B, Moberg PJ, Mozley LH et al. (2002) Memory-delineated subtypes of schizophrenia: Relationship to clinical, neuroanatomical and neurophysiological measures. Neuropsychology 16: 481-490
    • (2002) Neuropsychology , vol.16 , pp. 481
    • Turetsky1
  • 89
    • 33646584502 scopus 로고    scopus 로고
    • Üneri Ö, Tural Ü, Cakin Memik N (2006) Smoking and schizophrenia: Where is the biological connection? Turk J Psychiatry 17: 1-10
    • (2006) Turk J Psychiatry , vol.17 , pp. 1
    • Üneri1
  • 90
    • 0036959214 scopus 로고    scopus 로고
    • Woodruff-Pak DS, Lander C, Geerts H (2002) Nicotinic cholinergic modulation: galantamine as a prototype. CNS Drug Rev 8: 405-426
    • (2002) CNS Drug Rev , vol.8 , pp. 405
    • Woodruff-Pak1


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