Effect of galantamine on the human α7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity

British Journal of Pharmacology

Volumn 145, Issue 5, 2005, Pages 672-678

  Texidó, Laura ^a   Ros, Esteve ^a   Martín Satué, Mireia ^a   López, Susana ^a   Aleu, Jordi ^a   Marsal, Jordi ^a   Solsona, Carles ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Alzheimer's disease; Miniature endplate potential; Quantal synaptic transmission

Indexed keywords

ALPHA7 NEURONAL NICOTINIC RECEPTOR; CHOLINERGIC RECEPTOR BLOCKING AGENT; GALANTAMINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYNAPSE; CHOLINESTERASE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ELECTRIC ORGAN; FEMALE; MEMBRANE CURRENT; MINIATURE ENDPLATE POTENTIAL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTAL SYNAPTIC TRANSMISSION; RECEPTOR UPREGULATION; SYNAPTIC TRANSMISSION; TORPEDO MARMORATA; XENOPUS LAEVIS;

ANIMALS; CHOLINESTERASE INHIBITORS; FEMALE; GALANTAMINE; HUMANS; MEMBRANE POTENTIALS; NOOTROPIC AGENTS; OOCYTES; PARASYMPATHETIC NERVOUS SYSTEM; PATCH-CLAMP TECHNIQUES; RECEPTORS, NICOTINIC; SYNAPSES; SYNAPTIC TRANSMISSION; TORPEDO; XENOPUS LAEVIS;

EID: 22744458115     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706221     Document Type: Article

References (40)

1. ARAVANIS, A.M., PYLE, J.L. & TSIEN, R.W. (2003). Single synaptic vesicles fusing transiently and successively without loss of identity. Nature, 423, 643-647.
2. AULD, D.S., KORNECOOK, T.J., BASTIANETTO, S. & QUIRION, R. (2002). Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. Prog. Neurobiol., 68, 209-245.
3. BARTUS, R.T., DEAN III, R.L., BEER, B. & LIPPA, A.S. (1982). The cholinergic hypothesis of geriatric memory dysfunction. Science, 217, 408-414.
4. BRAILOIU, E. & MIYAMOTO, M.D. (2000). Inositol trisphosphate and cyclic adenosine diphosphate-ribose increase quantal transmitter release at frog motor nerve terminals: possible involvement of smooth endoplasmic reticulum. Neuroscience, 95, 927-931.
5. BRAILOIU, E., BRAILOIU, G.C., MIYAMOTO, M.D. & DUN, N.J. (2003). The vasoactive peptide urotensin II stimulates spontaneous release from frog motor nerve terminals. Br. J. Pharmacol., 138, 1580-1588.
6. CANTÍ, C., BODAS, E., MARSAL, J. & SOLSONA, C. (1998). Tacrine and physostigmine block nicotinic receptors in Xenopus oocytes injected with Torpedo electroplaque membranes. Eur. J. Pharmacol., 363, 197-202.
7. CANTÍ, C., MARTI, E., MARSAL, J. & SOLSONA, C. (1994). Tacrine-induced increase in the release of spontaneous high quantal content events in Torpedo electric organ. Br. J. Pharmacol., 112, 19-22.
8. COYLE, J.T., PRICE, D.L. & DELONG, M.R. (1983). Alzheimer's disease: a disorder of corticalcholinergic innervation. Science, 219, 1184-1190.
9. DALE, M.C., LIBRETTO, S.E., PATTERSON, C., ANDERSON, J., CHOUDHURY, T., MCCAFFERTY, F., MCWILLIAM, C. & RICHARDSON, M. (2003). Clinical experience of galantamine in dementia: a series of case reports. Curr. Med. Res. Opin., 19, 508-518.
10. DAVIES, P. & MALONEY, A.J. (1976). Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet, 2, 1403.
11. DUMONT, J.N. (1972). Oogenesis in Xenopus laevis (Daudin). I Stages of oocyte development in laboratory maintained animals. J. Morphol., 136, 153-179.
12. DUNANT, Y. & MULLER, D. (1986). Quantal release of acetylcholine evoked by focal depolarization at the Torpedo nerve-electroplaque junction. J. Physiol., 379, 461-478.
13. GANDHI, S.P. & STEVENS, C.F. (2003). Three modes of synaptic vesicular recycling revealed by single-vesicle imaging. Nature, 423, 607-613.
14. GIACOBINI, E. (2003). Cholinergic function and Alzheimer's disease. Int. J. Geriatr. Psychiatry, 18, 1-5.
15. KRALIZ, D. & SINGH, S. (1997). Selective blockade of the delayed rectifier potassium current by tacrine in Drosophila. J. Neurobiol., 32, 1-10.
16. LI, C.Y., WANG, H., XUE, H., CARLIER, P.R., HUI, K.M., PANG, Y.P., LI, Z.W. & HAN, Y.F. (1999). Bis(7)-tacrine, a novel dimeric AChE inhibitor, is a potent GABA(A) receptor antagonist. Neuroreport, 10, 795-800.
17. LÓPEZ, S., BASTIDA, J., VILADOMAT, F. & CODINA, C. (2002). Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus. Phytochem. Anal., 13, 311-315.
18. MAELICKE, A., COBAN, T., STORCH, A., SCHRATTENHOLZ, A., PEREIRA, E.F. & ALBUQUERQUE, E.X. (1997). Allosteric modulation of Torpedo nicotinic acetylcholine receptor ion channel activity by noncompetitive agonists. J. Recept. Signal. Transduct. Res., 17, 11-28.
19. MAELICKE, A., SAMOCHOCKI, M., JOSTOCK, R., FEHRENBACHER, A., LUDWIG, J., ALBUQUERQUE, E.X. & ZERLIN, M. (2001). Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease. Biol. Psychiatry, 49, 279-288.
20. MARSAL, J., TIGYI, G. & MILEDI, R. (1995). Incorporation of acetylcholine receptors and Cl- channels in Xenopus oocytes injected with Torpedo electroplaque membranes. Proc. Natl. Acad. Sci. U.S.A., 92, 5224-5228.
21. MILEDI, R. & WOODWARD, R.M. (1989). Effects of defolliculation on membrane current responses of Xenopus oocytes. J. Physiol., 416, 601-621.
22. MIWA, J.M., IBANEZ-TALLON, I., CRABTREE, G.W., SANCHEZ, R., SALI, A., ROLE, L.W. & HEINTZ, N. (1999). lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron, 23, 105-114.
23. MULLE, C., LENA, C. & CHANGEUX, J.P. (1992). Potentiation of nicotinic receptor response by external calcium in rat central neurons. Neuron, 8, 937-945.
24. MULLER, D. & DUNANT, Y. (1987). Spontaneous quantal and subquantal transmitter release at the Torpedo nerve-electroplaque junction. Neuroscience, 20, 911-921.
25. PAPKE, R.L., THINSCHMIDT, J.S., MOULTON, B.A., MEYER, E.M. & POIRIER, A. (1997). Activation and inhibition of rat neuronal nicotinic receptors by ABT-418. Br. J. Pharmacol., 120, 429-438.
26. PEREIRA, E.F., ALKONDON, M., REINHARDT, S., MAELICKE, A., PENG, X., LINDSTROM, J., WHITING, P. & ALBUQUERQUE, E.X. (1994). Physostigmine and galanthamine: probes for a novel binding site on the alpha 4 beta 2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells. J. Pharmacol. Exp. Ther., 270, 768-778.
27. PEREIRA, E.F., HILMAS, C., SANTOS, M.D., ALKONDON, M., MAELICKE, A. & ALBUQUERQUE, E.X. (2002). Unconventional ligands and modulators of nicotinic receptors. J. Neurobiol., 53, 479-500.
28. PEREIRA, E.F., REINHARDT-MAELICKE, S., SCHRATTENHOLZ, A., MAELICKE, A. & ALBUQUERQUE, E.X. (1993). Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons. J. Pharmacol. Exp. Ther., 265, 1474-1491.
29. ROS, E., ALEU, J., GOMEZ, D.E., ARANDA, I., CANTI, C., PANG, Y.P., MARSAL, J. & SOLSONA, C. (2001a). Effects of bis(7)-tacrine on spontaneous synaptic activity and on the nicotinic ACh receptor of Torpedo electric organ. J. Neurophysiol., 86, 183-189.
30. ROS, E., ALEU, J., GOMEZ, D.E., ARANDA, I., MUNOZ-TORRERO, D., CAMPS, P., BADIA, A., MARSAL, J. & SOLSONA, C. (2001b). The pharmacology of novel acetylcholinesterase inhibitors, (+/-)-huprines Y and X, on the Torpedo electric organ. Eur. J. Pharmacol., 421, 77-84.
31. ROS, E., ALEU, J., MARSAL, J. & SOLSONA, C. (2000). Effects of CI-1002 and CI-1017 on spontaneous synaptic activity and on the nicotinic acetylcholine receptor of Torpedo electric organ. Eur. J. Pharmacol., 390, 7-13.
32. SAMOCHOCKI, M., HOFFLE, A., FEHRENBACHER, A., JOSTOCK, R., LUDWIG, J., CHRISTNER, C., RADINA, M., ZERLIN, M., ULLMER, C., PEREIRA, E.F., LUBBERT, H., ALBUQUERQUE, E.X. & MAELICKE, A. (2003). Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J. Pharmacol. Exp. Ther., 305, 1024-1036.
33. SANTOS, M.D., ALKONDON, M., PEREIRA, E.F., ARACAVA, Y., EISENBERG, H.M., MAELICKE, A. & ALBUQUERQUE, E.X. (2002). The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system. Mol. Pharmacol., 61, 1222-1234.
34. SHARP, B.M., YATSULA, M. & FU, Y. (2004). Effects of galantamine, a nicotinic allosteric potentiating ligand, on nicotine-induced catecholamine release hippocampus and nucleus accumbens of rats. J. Pharmacol. Exp. Ther., 309, 1116-1123.
35. SHAW, K.P., ARACAVA, Y., AKAIKE, A., DALY, J.W., RICKETT, D.L. & ALBUQUERQUE, E.X. (1985). The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex. Mol. Pharmacol., 28, 527-538.
36. THOMSEN, T., KADEN, B., FISCHER, J.P., BICKEL, U., BARZ, H., GUSZTONY, G., CERVOS-NAVARRO, J. & KEWITZ, H. (1991). Inhibition of acetylcholinesterase activity in human brain tissue and erythrocytes by galanthamine, physostigmine and tacrine. Eur. J. Clin. Chem. Clin. Biochem., 29, 487-492.
37. VAN DER KLOOT, W. (1991). The regulation of quantal size. Prog. Neurobiol., 36, 93-130.
38. VERNINO, S., AMADOR, M., LUETJE, C.W., PATRICK, J. & DANI, J.A. (1992). Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron, 8, 127-134.
39. WOODRUFF-PAK, D.S., VOGEL III, R.W. & WENK, G.L. (2001). Galantamine: effect on nicotinic receptor binding, acetylcholinesterase inhibition, and learning. Proc. Natl. Acad. Sci. U.S.A., 98, 2089-2094.
40. ZHANG, L., ZHOU, F. & DANI, J.A. (2004). Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release. Mol. Pharmacol., 66, 538-544.